IL165989A0 - Process for producing a virus-inactivated thrombinpreparation - Google Patents

Process for producing a virus-inactivated thrombinpreparation

Info

Publication number
IL165989A0
IL165989A0 IL16598903A IL16598903A IL165989A0 IL 165989 A0 IL165989 A0 IL 165989A0 IL 16598903 A IL16598903 A IL 16598903A IL 16598903 A IL16598903 A IL 16598903A IL 165989 A0 IL165989 A0 IL 165989A0
Authority
IL
Israel
Prior art keywords
virus
thrombinpreparation
inactivated
producing
processes
Prior art date
Application number
IL16598903A
Other languages
English (en)
Original Assignee
Nat Blood Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Blood Authority filed Critical Nat Blood Authority
Publication of IL165989A0 publication Critical patent/IL165989A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6429Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088Liquid substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21005Thrombin (3.4.21.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL16598903A 2002-07-10 2003-07-07 Process for producing a virus-inactivated thrombinpreparation IL165989A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216002.6A GB0216002D0 (en) 2002-07-10 2002-07-10 Process and composition
PCT/GB2003/002942 WO2004007707A1 (en) 2002-07-10 2003-07-07 Process for producing a virus-inactivated thrombin preparation

Publications (1)

Publication Number Publication Date
IL165989A0 true IL165989A0 (en) 2006-01-15

Family

ID=9940204

Family Applications (3)

Application Number Title Priority Date Filing Date
IL16598903A IL165989A0 (en) 2002-07-10 2003-07-07 Process for producing a virus-inactivated thrombinpreparation
IL165989A IL165989A (en) 2002-07-10 2004-12-26 Process for producing a virus-inactivated thrombin preparation
IL201146A IL201146A (en) 2002-07-10 2009-09-23 A process for preparing a thrombin preparation in which the viruses have been taken out of action

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL165989A IL165989A (en) 2002-07-10 2004-12-26 Process for producing a virus-inactivated thrombin preparation
IL201146A IL201146A (en) 2002-07-10 2009-09-23 A process for preparing a thrombin preparation in which the viruses have been taken out of action

Country Status (19)

Country Link
US (1) US8435779B2 (xx)
EP (1) EP1520018B1 (xx)
JP (1) JP4445386B2 (xx)
AT (1) ATE354648T1 (xx)
AU (1) AU2003244858B2 (xx)
BR (1) BRPI0312522B8 (xx)
CA (1) CA2491718C (xx)
CY (1) CY1107632T1 (xx)
DE (1) DE60311990T2 (xx)
EC (1) ECSP055586A (xx)
ES (1) ES2282644T3 (xx)
GB (1) GB0216002D0 (xx)
IL (3) IL165989A0 (xx)
MX (1) MXPA05000393A (xx)
NO (1) NO20050090L (xx)
NZ (1) NZ537502A (xx)
PL (1) PL208219B1 (xx)
PT (1) PT1520018E (xx)
WO (1) WO2004007707A1 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2572327A1 (en) * 2004-06-29 2006-02-02 Reliance Life Sciences Pvt. Ltd. Process for the preparation of virus-safe biological fluids
EP1685852A1 (en) * 2005-02-01 2006-08-02 Fondation pour la Recherche Diagnostique Set of disposable bags for viral inactivation of biological fluids
US20060270015A1 (en) * 2005-05-26 2006-11-30 Dan Pawlak Thrombin purification
US20070148151A1 (en) 2005-07-29 2007-06-28 Martin Frink Processes for the manufacture and use of pancreatin
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
PL2027263T3 (pl) * 2006-05-22 2013-01-31 Abbott Laboratories Gmbh Sposób separacji i określenia wiremii w próbce pankreatyny
US7774628B2 (en) * 2006-05-25 2010-08-10 Foundry Networks, Inc. Enabling/disabling power-over-ethernet software subsystem in response to power supply status
KR20100134078A (ko) * 2008-04-16 2010-12-22 잇빤 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 트롬빈 고정화 생체 흡수성 시트 제제의 제조방법
JP5442310B2 (ja) * 2009-04-23 2014-03-12 旭化成メディカル株式会社 トロンビン溶液の調製方法
US8945895B2 (en) * 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
AU2015252061A1 (en) * 2009-07-31 2015-11-19 Baxalta GmbH Method for Purifying Recombinant ADAMTS13 and Other Proteins and Compositions Thereof
SE1050124A1 (sv) * 2010-02-08 2011-08-09 Linkoping Biocontrols Ab Stabil lösning
CN102357259A (zh) * 2011-07-28 2012-02-22 王珊珊 一种生物蛋白海绵及其制备方法
JP6297029B2 (ja) * 2012-05-31 2018-03-20 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ 多様な官能基を有する粒子による免疫グロブリンg調製物のクロマトグラフィー精製
US9932388B2 (en) 2014-11-13 2018-04-03 Hemarus Therapeutics Limited Chromatographic process for producing high purity fibrinogen and thrombin
CN113754757A (zh) * 2021-07-01 2021-12-07 华兰生物工程股份有限公司 一种人纤维蛋白原的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336631A1 (de) * 1983-10-08 1985-04-18 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von plasma oder von konzentraten der blutgerinnungsfaktoren ii, vii, ix und x
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
IE73210B1 (en) * 1990-01-24 1997-05-07 Warner Lambert Co Process for the production of thrombin and high purity thrombin preparation thereby obtained
EP0443724B1 (en) * 1990-02-20 1999-03-17 Baxter International Inc. Viral-safe purified human thrombin
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.
AT398079B (de) * 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
DE4137996A1 (de) * 1991-11-19 1993-05-27 Behringwerke Ag Verfahren zur herstellung eines virussicheren thrombinkonzentrates
AT397390B (de) * 1992-04-06 1994-03-25 Immuno Ag Verfahren zur spaltung von proteinen
GB9503750D0 (en) * 1995-02-24 1995-04-12 Common Services Agency Thrombin preparation
AT500670A1 (de) * 1999-05-19 2006-02-15 Bio & Bio Licensing Sa Arzneimittel zur lokalen anwendung
US6245548B1 (en) * 2000-03-09 2001-06-12 American National Red Cross Activation of pure prothrombin to thrombin with about 30% to about 40% sodium citrate
DE10012732A1 (de) * 2000-03-18 2001-09-20 Aventis Behring Gmbh Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung
IL136552A (en) 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
US20030133829A1 (en) * 2001-12-21 2003-07-17 Baxter Healthcare Corporation Process for inactivating pathogens in a biological material

Also Published As

Publication number Publication date
DE60311990T2 (de) 2007-11-08
BR0312522A (pt) 2005-04-19
IL165989A (en) 2010-11-30
DE60311990D1 (de) 2007-04-05
GB0216002D0 (en) 2002-08-21
NZ537502A (en) 2007-12-21
WO2004007707A1 (en) 2004-01-22
IL201146A (en) 2011-05-31
BRPI0312522B1 (pt) 2019-01-02
EP1520018A1 (en) 2005-04-06
PT1520018E (pt) 2007-04-30
BRPI0312522B8 (pt) 2021-05-25
AU2003244858A1 (en) 2004-02-02
US20060134769A1 (en) 2006-06-22
CA2491718C (en) 2013-10-22
ATE354648T1 (de) 2007-03-15
CA2491718A1 (en) 2004-01-22
US8435779B2 (en) 2013-05-07
AU2003244858B2 (en) 2008-01-31
ES2282644T3 (es) 2007-10-16
MXPA05000393A (es) 2005-07-22
JP2005532073A (ja) 2005-10-27
EP1520018B1 (en) 2007-02-21
NO20050090L (no) 2005-04-08
JP4445386B2 (ja) 2010-04-07
PL374747A1 (en) 2005-10-31
ECSP055586A (es) 2005-07-06
PL208219B1 (pl) 2011-03-31
CY1107632T1 (el) 2013-04-18

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