IL164904A0 - Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-Ä(2-methyl-1H-imidazol-1-YL)methylÜ-4H-carbazol-4-one - Google Patents

Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-Ä(2-methyl-1H-imidazol-1-YL)methylÜ-4H-carbazol-4-one

Info

Publication number
IL164904A0
IL164904A0 IL16490404A IL16490404A IL164904A0 IL 164904 A0 IL164904 A0 IL 164904A0 IL 16490404 A IL16490404 A IL 16490404A IL 16490404 A IL16490404 A IL 16490404A IL 164904 A0 IL164904 A0 IL 164904A0
Authority
IL
Israel
Prior art keywords
methyl
preparing
methylü
carbazol
imidazol
Prior art date
Application number
IL16490404A
Other languages
English (en)
Original Assignee
Biogal Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Pharmaceutical Co Ltd filed Critical Biogal Pharmaceutical Co Ltd
Publication of IL164904A0 publication Critical patent/IL164904A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D521/00—Heterocyclic compounds containing unspecified hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IL16490404A 2002-04-29 2004-10-28 Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-Ä(2-methyl-1H-imidazol-1-YL)methylÜ-4H-carbazol-4-one IL164904A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37632302P 2002-04-29 2002-04-29
PCT/US2003/013221 WO2003093281A1 (fr) 2002-04-29 2003-04-29 Methode de preparation de 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1h-imidazol-1-yl)methyl]-4h-carbazol-4-one

Publications (1)

Publication Number Publication Date
IL164904A0 true IL164904A0 (en) 2005-12-18

Family

ID=29401332

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16490404A IL164904A0 (en) 2002-04-29 2004-10-28 Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-Ä(2-methyl-1H-imidazol-1-YL)methylÜ-4H-carbazol-4-one

Country Status (19)

Country Link
US (2) US7098345B2 (fr)
EP (1) EP1499623B1 (fr)
JP (1) JP2005529142A (fr)
KR (1) KR20040104654A (fr)
CN (1) CN1665823A (fr)
AT (1) ATE364611T1 (fr)
AU (1) AU2003223764A1 (fr)
CA (1) CA2483566A1 (fr)
DE (1) DE60314400T2 (fr)
DK (1) DK1499623T3 (fr)
ES (1) ES2288606T3 (fr)
HR (1) HRP20041070A2 (fr)
IL (1) IL164904A0 (fr)
MX (1) MXPA04010846A (fr)
NO (1) NO20045192L (fr)
PL (1) PL373191A1 (fr)
PT (1) PT1499623E (fr)
WO (1) WO2003093281A1 (fr)
ZA (1) ZA200408934B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002230935A1 (en) * 2000-10-30 2002-05-15 Teva Pharmaceutical Industries Ltd. Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation
US20050131045A1 (en) * 2002-04-30 2005-06-16 Judith Aronhime Novel crystal forms of ondansetron, processes for their preparation, pharmaceutical, compositions containing the novel forms and methods for treating nausea using them
EP1465887A1 (fr) * 2002-04-30 2004-10-13 Teva Gyogyszergyar Reszvenytarsasag Nouvelles formes cristallines d'ondansetron, procedes de preparation correspondant, compositions pharmaceutiques contenant ces nouvelles formes et procedes de traitement de la nausee au moyen des ces nouvelles formes
US7696356B2 (en) * 2004-08-17 2010-04-13 Taro Pharmaceutical Industries Limited Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom
EP1828141A4 (fr) * 2004-10-26 2009-04-01 Ipca Lab Ltd Procede monotope de preparation de l'agent antiemetique 1,2,3,9-tetrahydro-9-methyl-3[(2-methyl-1h-imidazole-1-yl)methyl]-4h-carbazol-4-one

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502508A1 (de) 1984-01-25 1985-08-14 Glaxo Group Ltd., London Heterocyclische verbindungen
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
DE3689974T2 (de) 1985-03-14 1994-11-03 Beecham Group Plc Arzneimittel zur Behandlung von Emesis.
GB8518741D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518742D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518745D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
US4859662A (en) 1986-11-28 1989-08-22 Glaxo Group Limited Tetrahydro-imidazolylmethylcarbazolones and analogs thereof for treating 5-HT function disturbances
GB8630071D0 (en) 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5344658A (en) 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
GB8914804D0 (en) 1989-06-28 1989-08-16 Glaxo Group Ltd Process
WO1993000074A1 (fr) 1991-06-26 1993-01-07 Sepracor, Inc. Methodes et compositions pour le traitement des vomissements, de la nausee et d'autres troubles faisant appel a l'ondansetron optiquement pur r(+)
CA2106642C (fr) 1992-10-14 2005-08-16 Peter Bod Derives de carbazolone et procede d'obtention
GB9423588D0 (en) 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423511D0 (en) 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
CN1045437C (zh) 1994-12-29 1999-10-06 中国科学院上海有机化学研究所 恩丹西酮及其生理盐的合成
AU2002230935A1 (en) 2000-10-30 2002-05-15 Teva Pharmaceutical Industries Ltd. Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation
EP1207160A1 (fr) 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Procédé de préparation de la 1,2,3,9-tétrahydro-9-méthyl-3-((2-méthyl-1H-imidazol-1-yl)-méthyl)-4H-carbazol-4-one
MXPA03006215A (es) 2001-01-11 2005-02-17 Teva Pharma Un proceso mejorado para preparar clorhidrato de ondansetron dihidratado puro.
WO2003090730A1 (fr) 2002-04-25 2003-11-06 Generics [Uk] Limited Nouvelles formes cristallines de celecoxib et d'autres composes
EP1465887A1 (fr) 2002-04-30 2004-10-13 Teva Gyogyszergyar Reszvenytarsasag Nouvelles formes cristallines d'ondansetron, procedes de preparation correspondant, compositions pharmaceutiques contenant ces nouvelles formes et procedes de traitement de la nausee au moyen des ces nouvelles formes

Also Published As

Publication number Publication date
DE60314400D1 (de) 2007-07-26
EP1499623A1 (fr) 2005-01-26
ATE364611T1 (de) 2007-07-15
CN1665823A (zh) 2005-09-07
PT1499623E (pt) 2007-08-10
PL373191A1 (en) 2005-08-22
WO2003093281A1 (fr) 2003-11-13
US20060252942A1 (en) 2006-11-09
JP2005529142A (ja) 2005-09-29
DK1499623T3 (da) 2007-10-08
HRP20041070A2 (en) 2005-02-28
CA2483566A1 (fr) 2003-11-13
AU2003223764A1 (en) 2003-11-17
EP1499623B1 (fr) 2007-06-13
US20050020655A1 (en) 2005-01-27
US7098345B2 (en) 2006-08-29
KR20040104654A (ko) 2004-12-10
DE60314400T2 (de) 2008-02-07
NO20045192L (no) 2005-01-28
MXPA04010846A (es) 2005-01-25
ES2288606T3 (es) 2008-01-16
ZA200408934B (en) 2006-07-26

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