IL164247A0 - Method for preparing combretastatins - Google Patents

Method for preparing combretastatins

Info

Publication number
IL164247A0
IL164247A0 IL16424703A IL16424703A IL164247A0 IL 164247 A0 IL164247 A0 IL 164247A0 IL 16424703 A IL16424703 A IL 16424703A IL 16424703 A IL16424703 A IL 16424703A IL 164247 A0 IL164247 A0 IL 164247A0
Authority
IL
Israel
Prior art keywords
combretastatins
preparing
preparing combretastatins
Prior art date
Application number
IL16424703A
Other languages
English (en)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of IL164247A0 publication Critical patent/IL164247A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
    • C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
IL16424703A 2002-04-11 2003-04-09 Method for preparing combretastatins IL164247A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0204499A FR2838437B1 (fr) 2002-04-11 2002-04-11 Procedes de preparation de combretastatines
PCT/FR2003/001117 WO2003084919A2 (fr) 2002-04-11 2003-04-09 Procedes de preparation de combretastatines

Publications (1)

Publication Number Publication Date
IL164247A0 true IL164247A0 (en) 2005-12-18

Family

ID=28459732

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16424703A IL164247A0 (en) 2002-04-11 2003-04-09 Method for preparing combretastatins

Country Status (28)

Country Link
EP (3) EP1497255A2 (xx)
JP (1) JP4299677B2 (xx)
KR (1) KR101018983B1 (xx)
CN (1) CN1291970C (xx)
AR (2) AR039198A1 (xx)
AU (1) AU2003260026B2 (xx)
BR (1) BR0309087A (xx)
CA (1) CA2481742C (xx)
CR (1) CR7481A (xx)
EA (1) EA007965B1 (xx)
EC (1) ECSP045348A (xx)
FR (1) FR2838437B1 (xx)
HK (1) HK1075651A1 (xx)
HR (1) HRP20040935A2 (xx)
IL (1) IL164247A0 (xx)
MA (1) MA26407A1 (xx)
ME (1) MEP91508A (xx)
MX (1) MXPA04009112A (xx)
NO (2) NO329701B1 (xx)
NZ (1) NZ535318A (xx)
OA (1) OA12804A (xx)
PL (3) PL214129B1 (xx)
RS (3) RS52331B (xx)
TN (1) TNSN04201A1 (xx)
TW (1) TWI262179B (xx)
UA (1) UA76079C2 (xx)
WO (1) WO2003084919A2 (xx)
ZA (1) ZA200407417B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7235688B1 (en) 2004-11-04 2007-06-26 University Of Notre Dame Du Lac Process for preparing histone deacetylase inhibitors and intermediates thereof
FR2928148B1 (fr) * 2008-02-28 2013-01-18 Sanofi Aventis Procede de preparation de combretastatine
FR2939665B1 (fr) 2008-12-12 2011-10-07 Sanofi Aventis Combinaison antitumorale associant l'ave8062a et le docetaxel
FR2945210B1 (fr) 2009-05-07 2011-07-01 Sanofi Aventis Combinaison antitumorale comprenant l'ave8062 et le sorafenib
FR2953518B1 (fr) 2009-12-03 2012-01-20 Sanofi Aventis Procede de preparation d'un derive de combretastatine
EP2397135A1 (en) 2010-06-18 2011-12-21 Sanofi An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
EP2481404A1 (en) 2010-11-15 2012-08-01 Sanofi An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
KR20130088753A (ko) 2010-06-18 2013-08-08 사노피 옴브라불린, 탁산 유도체 및 백금 유도체를 포함하는 항종양 조합물
EP2407161A1 (en) 2010-07-13 2012-01-18 Sanofi An antitumoral combination comprising ombrabulin and bevacizumab
FR2968557A1 (fr) 2010-12-09 2012-06-15 Sanofi Aventis Combinaison antitumorale comprenant un derive de la famille des combretastatines et le cetuximab
FR2978662A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cisplatine, associee a la radiotherapie
FR2978663A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cetuximab, associee a la radiotherapie
CN103012248B (zh) * 2013-01-11 2014-11-05 浙江大德药业集团有限公司 氨基康普立停衍生物的合成及其作为口服抗肿瘤药物的应用
EP3184095A1 (en) 2013-05-23 2017-06-28 IP Gesellschaft für Management mbH Administration units comprising polymorph 1 of 2-(2-methylamino-pyrimidin-4-yl]-1h-indole-5-carboxylic acid [(s)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide
EP4079327A1 (en) 2021-04-22 2022-10-26 Centaurus Polytherapeutics Payloads for drug-conjugates and their use for treating cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996237A (en) 1987-01-06 1991-02-26 Arizona Board Of Regents Combretastatin A-4
UA18265A (uk) * 1988-02-24 1997-12-25 Ф.Хоффманн-Ля Рош Аг Спосіб одержаhhя похідhих стильбеhу
NZ232897A (en) * 1989-04-03 1992-12-23 Squibb & Sons Inc Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogues, preparation and pharmaceutical compositions thereof
US5731353A (en) * 1993-09-08 1998-03-24 Ajinomoto Co., Inc. Stilbene derivatives and pharmaceutical compositions containing them
TW325458B (en) * 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
CA2187214C (en) * 1994-04-06 2002-03-12 Hiroyoshi Hidaka Aminostilbazole derivative and medicine
TW334418B (en) * 1995-03-07 1998-06-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions
JP4551514B2 (ja) * 1999-07-23 2010-09-29 住友化学株式会社 不飽和炭化水素残基置換アニリン類の製造方法
GB9918912D0 (en) 1999-08-12 1999-10-13 Angiogene Pharm Ltd New stilbenes with vascular damaging activity

Also Published As

Publication number Publication date
CN1291970C (zh) 2006-12-27
CR7481A (es) 2008-11-25
CA2481742A1 (fr) 2003-10-16
JP2005522478A (ja) 2005-07-28
RS20110562A2 (xx) 2012-10-31
JP4299677B2 (ja) 2009-07-22
AR039198A1 (es) 2005-02-09
FR2838437B1 (fr) 2004-06-04
EP2354118A1 (fr) 2011-08-10
PL214129B1 (pl) 2013-06-28
RS52331B (en) 2012-12-31
AR082581A2 (es) 2012-12-19
PL213708B1 (pl) 2013-04-30
KR101018983B1 (ko) 2011-03-07
ZA200407417B (en) 2006-04-26
CN1646476A (zh) 2005-07-27
HK1075651A1 (en) 2005-12-23
AU2003260026B2 (en) 2008-01-03
WO2003084919A2 (fr) 2003-10-16
TWI262179B (en) 2006-09-21
MA26407A1 (fr) 2004-12-01
ECSP045348A (es) 2004-11-26
AU2003260026A1 (en) 2003-10-20
TW200401762A (en) 2004-02-01
NO331372B1 (no) 2011-12-12
NO20101215L (no) 2004-01-07
PL371629A1 (en) 2005-06-27
PL394821A1 (pl) 2011-09-12
HRP20040935A2 (en) 2005-10-31
CA2481742C (fr) 2012-06-19
RS86504A (xx) 2007-02-05
BR0309087A (pt) 2005-02-09
NO329701B1 (no) 2010-12-06
MXPA04009112A (es) 2004-12-07
EP1497255A2 (fr) 2005-01-19
NO20044814L (no) 2004-01-07
MEP91508A (en) 2011-12-20
RS20110561A3 (xx) 2013-10-31
WO2003084919A3 (fr) 2004-04-08
FR2838437A1 (fr) 2003-10-17
TNSN04201A1 (fr) 2007-03-12
EA200401350A1 (ru) 2005-02-24
KR20040108717A (ko) 2004-12-24
NZ535318A (en) 2007-02-23
EA007965B1 (ru) 2007-02-27
RS20110562A3 (xx) 2013-12-31
PL394820A1 (pl) 2011-09-12
EP2348012A1 (fr) 2011-07-27
PL213967B1 (pl) 2013-05-31
RS20110561A2 (xx) 2012-10-31
UA76079C2 (en) 2006-06-15
OA12804A (fr) 2006-07-11

Similar Documents

Publication Publication Date Title
HK1075651A1 (en) Method for preparing combretastatins
GB0208104D0 (en) Method
GB0203306D0 (en) Method
AU2003250196A8 (en) Method for preparing oligonucleotides
GB0211975D0 (en) Method
AU2003258070A8 (en) Electrodionization method
GB0214209D0 (en) Method
EP1732394A4 (en) DEHYDRATION-GRIDING PROCESS
GB0205509D0 (en) Method
GB0213261D0 (en) Method
GB0209296D0 (en) Method
AU2003253813A8 (en) Method for colpoplasty
AU2003222342A8 (en) Method for preparing $g(v)-bromoalkylcarboxylic compounds
EP1556396A4 (en) METHOD OF PRODUCING 2-DESOXY-L-RIBOSE
AM1402A2 (en) Hardtack preparing method
GB0208383D0 (en) Method
GB0200865D0 (en) Method
AU2002367923A8 (en) Method for preparing 2-alkoxyphenoxyethanamines from 2-alkoxyphenoxyethylacetamides
GB0207266D0 (en) Method
GB0326529D0 (en) Positioning method
GB0205469D0 (en) Method
GB0211923D0 (en) Method
GB0205864D0 (en) Method
GB0204114D0 (en) Method
GB0221569D0 (en) Method

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees