IL163599A0 - Host cells having improved cell survival properties and methods to generate such cells - Google Patents

Host cells having improved cell survival properties and methods to generate such cells

Info

Publication number
IL163599A0
IL163599A0 IL16359903A IL16359903A IL163599A0 IL 163599 A0 IL163599 A0 IL 163599A0 IL 16359903 A IL16359903 A IL 16359903A IL 16359903 A IL16359903 A IL 16359903A IL 163599 A0 IL163599 A0 IL 163599A0
Authority
IL
Israel
Prior art keywords
cells
generate
methods
cell survival
improved cell
Prior art date
Application number
IL16359903A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL163599A0 publication Critical patent/IL163599A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/48—Regulators of apoptosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL16359903A 2002-03-28 2003-03-25 Host cells having improved cell survival properties and methods to generate such cells IL163599A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02007144A EP1348758A1 (fr) 2002-03-28 2002-03-28 Cellules hôtes ayant des propriétés de survie améliorées et procédé pour produire ces cellules
PCT/EP2003/003063 WO2003083093A1 (fr) 2002-03-28 2003-03-25 Cellules hotes presentant des proprietes de survie cellulaire ameliorees, et procede de production de telles cellules

Publications (1)

Publication Number Publication Date
IL163599A0 true IL163599A0 (en) 2005-12-18

Family

ID=27798823

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16359903A IL163599A0 (en) 2002-03-28 2003-03-25 Host cells having improved cell survival properties and methods to generate such cells

Country Status (19)

Country Link
EP (2) EP1348758A1 (fr)
JP (1) JP2005521406A (fr)
KR (1) KR101080626B1 (fr)
CN (1) CN1646683A (fr)
AR (1) AR039185A1 (fr)
AT (1) ATE459705T1 (fr)
AU (1) AU2003222777A1 (fr)
BR (1) BR0308810A (fr)
CA (1) CA2480684C (fr)
DE (1) DE60331529D1 (fr)
DK (1) DK1490482T3 (fr)
ES (1) ES2339760T3 (fr)
IL (1) IL163599A0 (fr)
MX (1) MXPA04009336A (fr)
NZ (1) NZ536077A (fr)
PE (1) PE20040166A1 (fr)
TW (2) TWI332991B (fr)
UY (1) UY27739A1 (fr)
WO (1) WO2003083093A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040044433A (ko) 2001-07-10 2004-05-28 아이덱 파마슈티칼즈 코포레이션 세포자멸사 과정의 저해 및 세포 기능의 개선
KR100454016B1 (ko) * 2002-01-05 2004-10-26 한국과학기술원 항예정사 유전자로 형질전환되고 ｄｈｆｒ 유전자가결핍된 신규한 ｃｈｏ 세포주, 그의 제조 방법 및 상기형질전환된 ｃｈｏ 숙주 세포를 이용한 목적단백질의 생산방법
EP1563073A4 (fr) * 2002-06-26 2007-09-19 Biogen Idec Inc Procedes de production de proteine et cellules modifiees pour utilisation dans ces procedes
WO2004062554A2 (fr) * 2003-01-08 2004-07-29 Nsgene A/S Augmentation de la production et de la survie neuronale
ATE465245T1 (de) * 2003-10-24 2010-05-15 Chemo Sero Therapeut Res Inst Neue rekombinante tierzellen mit hoher proteinproduktion, verfahren zur konstruktion davon sowie verfahren zur massenproduktion von protein unter verwendung davon
US7537930B2 (en) 2004-07-23 2009-05-26 Immunomedics, Inc. Mammalian cell lines for increasing longevity and protein yield from a cell culture
US7608425B2 (en) 2004-07-23 2009-10-27 Immunomedics, Inc. Methods for protein expression in mammalian cells in serum-free medium
US7531327B2 (en) * 2004-07-23 2009-05-12 Immunomedics, Inc. Methods and compositions for increasing longevity and protein yield from a cell culture
EP1953222A1 (fr) * 2007-01-24 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Amélioration de la croissance de céllules
US20110281301A1 (en) * 2007-11-13 2011-11-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg The secretory capacity in host cells
UA106047C2 (uk) * 2008-06-13 2014-07-25 Сентокор Орто Байотек Інк. Спосіб отримання високої щільності життєздатних клітин в культурі клітин ссавців
AR072832A1 (es) 2008-07-23 2010-09-22 Boehringer Ingelheim Pharma LINEAS DE CELULAS HOSPEDANTES DE PRODUCCION MEJORADA QUE CONTIENEN CONSTRUCCIONES DE VECTORES QUE COMPRENDEN UN CASETE DE EXPRESIoN DE DHFR (ENZIMA DIHIDROFOLATO REDUCTASA).
AU2012321088B8 (en) * 2011-12-02 2016-12-15 Fate Therapeutics, Inc. Enhanced stem cell composition
CN104673754B (zh) * 2015-02-14 2018-03-02 百泰生物药业有限公司 重组骨髓瘤细胞克隆的筛选方法及由此获得的抗体分子
JP7214962B2 (ja) * 2018-01-17 2023-01-31 東ソー株式会社 アルカリホスファターゼ高発現動物細胞

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143291A (en) * 1995-05-04 2000-11-07 Us Navy Methods for modulating T cell survival by modulating bcl-XL protein level
WO2000075291A2 (fr) * 1999-06-08 2000-12-14 Novartis Ag EXPRESSION FORCEE DE BCL-xL

Also Published As

Publication number Publication date
PE20040166A1 (es) 2004-05-20
UY27739A1 (es) 2003-10-31
AR039185A1 (es) 2005-02-09
BR0308810A (pt) 2005-06-28
TW201000633A (en) 2010-01-01
EP1490482A1 (fr) 2004-12-29
CA2480684A1 (fr) 2003-10-09
CA2480684C (fr) 2011-01-25
DK1490482T3 (da) 2010-07-05
CN1646683A (zh) 2005-07-27
EP1348758A1 (fr) 2003-10-01
ES2339760T3 (es) 2010-05-25
MXPA04009336A (es) 2005-01-25
EP1490482B1 (fr) 2010-03-03
TWI332990B (en) 2010-11-11
NZ536077A (en) 2006-04-28
ATE459705T1 (de) 2010-03-15
AU2003222777A1 (en) 2003-10-13
WO2003083093A1 (fr) 2003-10-09
TWI332991B (en) 2010-11-11
DE60331529D1 (de) 2010-04-15
JP2005521406A (ja) 2005-07-21
TW200307044A (en) 2003-12-01
KR101080626B1 (ko) 2011-11-08
KR20040099373A (ko) 2004-11-26

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