IL159998A0 - Autologous t-cell vaccines materials and methods - Google Patents
Autologous t-cell vaccines materials and methodsInfo
- Publication number
- IL159998A0 IL159998A0 IL15999802A IL15999802A IL159998A0 IL 159998 A0 IL159998 A0 IL 159998A0 IL 15999802 A IL15999802 A IL 15999802A IL 15999802 A IL15999802 A IL 15999802A IL 159998 A0 IL159998 A0 IL 159998A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- autologous
- cell vaccines
- vaccines materials
- materials
- Prior art date
Links
- 229940030156 cell vaccine Drugs 0.000 title abstract 3
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/22—Immunosuppressive or immunotolerising
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/414—Nervous system antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/952,532 US7658926B2 (en) | 2001-09-14 | 2001-09-14 | Autologous T-cell vaccines materials and methods |
| PCT/US2002/028874 WO2003024393A2 (en) | 2001-09-14 | 2002-09-12 | Autologous t-cell vaccines materials and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL159998A0 true IL159998A0 (en) | 2004-06-20 |
Family
ID=25492995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15999802A IL159998A0 (en) | 2001-09-14 | 2002-09-12 | Autologous t-cell vaccines materials and methods |
| IL196900A IL196900A (en) | 2001-09-14 | 2009-02-04 | Autologous T cell vaccine compositions |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL196900A IL196900A (en) | 2001-09-14 | 2009-02-04 | Autologous T cell vaccine compositions |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7658926B2 (pl) |
| EP (3) | EP2335720B1 (pl) |
| JP (5) | JP2005502721A (pl) |
| KR (1) | KR20040066787A (pl) |
| CN (2) | CN101229370B (pl) |
| AT (1) | ATE395076T1 (pl) |
| AU (1) | AU2002339914B2 (pl) |
| BR (1) | BR0212504A (pl) |
| CA (1) | CA2459969C (pl) |
| DE (1) | DE60226612D1 (pl) |
| DK (2) | DK2335720T3 (pl) |
| ES (2) | ES2306792T3 (pl) |
| HU (1) | HUP0401519A3 (pl) |
| IL (2) | IL159998A0 (pl) |
| MX (1) | MXPA04001862A (pl) |
| NZ (1) | NZ530762A (pl) |
| PL (1) | PL210442B1 (pl) |
| PT (2) | PT2335720E (pl) |
| RU (1) | RU2302257C2 (pl) |
| WO (1) | WO2003024393A2 (pl) |
| ZA (1) | ZA200401502B (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020009448A1 (en) * | 1997-09-19 | 2002-01-24 | Leslie P. Weiner | T-cell vaccination for the treatment of multiple sclerosis |
| US7658926B2 (en) | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
| US7744893B2 (en) * | 2002-06-05 | 2010-06-29 | Baylor College Of Medicine | T cell receptor CDR3 sequences associated with multiple sclerosis and compositions comprising same |
| PL214283B1 (pl) * | 2002-08-08 | 2013-07-31 | Baylor College Medicine | Sposób izolacji komórek T, sposób wytwarzania autologicznej szczepionki komórek T, autologiczna szczepionka komórek T, zastosowanie autologicznej szczepionki komórek T |
| EP1583823A4 (en) * | 2002-12-31 | 2006-02-22 | Baylor College Medicine | ISOLATION AND IDENTIFICATION OF CROSS-REACTIVE T CELLS |
| BRPI0415519A (pt) * | 2003-10-17 | 2006-12-26 | Baylor College Medicine | método para aumento das respostas de célula t citotóxica cd8+ e para tratamento de esclerose múltipla |
| WO2007131210A2 (en) * | 2006-05-05 | 2007-11-15 | Opexa Therapeutics | T-cell vaccine |
| RU2339385C1 (ru) * | 2007-04-02 | 2008-11-27 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Способ лечения ревматоидного артрита |
| ES2552678T3 (es) | 2008-06-30 | 2015-12-01 | Universitätsklinikum Heidelberg | Células sanguíneas inmunosupresoras y métodos de producir las mismas |
| RU2393218C1 (ru) * | 2009-01-30 | 2010-06-27 | Федеральное государственное учреждение "Центральный научно-исследовательский институт травматологии и ортопедии имени Н.Н. Приорова Росмедтехнологий" | Среда для выращивания культуры аутологичных лимфоцитов |
| WO2016037123A2 (en) * | 2014-09-05 | 2016-03-10 | Opexa Therapeutics, Inc. | Compositions and methods for treating b cell mediated autoimmune disorders |
| CN109125717B (zh) * | 2017-09-08 | 2022-02-22 | 江苏苏博生物医学股份有限公司 | 一种治疗慢性病的自体全细胞疫苗配方及其制备方法 |
| US20210061875A1 (en) | 2017-12-29 | 2021-03-04 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Compositions and methods for treating autoimmune disease |
Family Cites Families (65)
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|---|---|---|---|---|
| JPS5852225A (ja) | 1981-09-22 | 1983-03-28 | Mitsui Pharmaceut Inc | 脱髄疾患治療剤 |
| US5766920A (en) | 1982-08-11 | 1998-06-16 | Cellcor, Inc. | Ex vivo activation of immune cells |
| US4550086A (en) | 1983-02-16 | 1985-10-29 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies that recognize human T cells |
| IL69686A (en) | 1983-09-11 | 1988-03-31 | Yeda Res & Dev | Compositions containing cell membrane proteins and process for their preparation |
| US4608365A (en) | 1984-03-30 | 1986-08-26 | University Of Southern California | Treatment of neurologic functions |
| US4677061A (en) | 1984-10-19 | 1987-06-30 | Genetic Systems Corporation | T-cell lymphocyte subset monitoring of immunologic disease |
| US4898856A (en) | 1984-10-29 | 1990-02-06 | Chaovanee Aroonsakul | Method for treating central nervous system diseases |
| US4897389A (en) | 1984-10-29 | 1990-01-30 | Chaovanee Aroonsakul | Treating central nervous system diseases |
| US4902680A (en) | 1984-10-29 | 1990-02-20 | Chaovanee Aroonsakul | Treating central nervous system diseases |
| US4898857A (en) | 1984-10-29 | 1990-02-06 | Chaovanee Aroonsakul | Treating control nervous system diseases |
| CA1296622C (en) | 1986-08-12 | 1992-03-03 | Jeffrey E. Anderson | Method and apparatus for automated assessment of the immunoregulatory status of the mononuclear leukocyte immune system |
| US5849298A (en) | 1987-06-24 | 1998-12-15 | Autoimmune Inc. | Treatment of multiple sclerosis by oral administration of bovine myelin |
| US5039660A (en) | 1988-03-02 | 1991-08-13 | Endocon, Inc. | Partially fused peptide pellet |
| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5612035A (en) * | 1989-03-21 | 1997-03-18 | The Immune Response Corporation | Vaccination against diseases resulting from pathogenic responses by specific T cell populations |
| US6007815A (en) | 1989-03-21 | 1999-12-28 | The Immune Response Corporation | Anti-idiotype vaccination against diseases resulting from pathogenic responses by specific T cell populations |
| US6221352B1 (en) | 1989-03-21 | 2001-04-24 | The Immune Response Corporation | Method of preventing the proliferation of Vβ14 or Vβ17-Expressing T cells |
| US5861164A (en) | 1989-03-21 | 1999-01-19 | The Immune Response Corporation | Vaccination against diseases resulting from pathogenic responses by specific T cell populations |
| US5837246A (en) | 1989-03-21 | 1998-11-17 | The Immune Response Corporation | Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations |
| US6207645B1 (en) | 1989-03-21 | 2001-03-27 | The Immune Response Corporation | Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations |
| US5614192A (en) | 1989-07-19 | 1997-03-25 | Connective Therapeutics, Inc. | T cell receptor peptides as therapeutics for immune-related disease |
| US5776459A (en) | 1989-07-19 | 1998-07-07 | Connetics Corporation | TCR V beta 5 peptides |
| US5298396A (en) | 1989-11-15 | 1994-03-29 | National Jewish Center For Immunology And Respiratory Medicine | Method for identifying T cells disease involved in autoimmune disease |
| IL165071A (en) | 1990-03-30 | 2008-06-05 | Autoimmune Inc | A peptide with the ability to stimulate a subset of T cells from multiple sclerosis patients |
| AU8407091A (en) | 1990-07-06 | 1992-02-04 | Allergene, Inc. | Mouse/human heterohybrid cell line el41 and methods for the production of human monoclonal antibodies |
| US5668117A (en) | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| US5211952A (en) | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
| US6083503A (en) | 1991-08-28 | 2000-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Interleukin-2 stimulated T lymphocyte cell death for the treatment of autoimmune diseases, allergic responses, and graft rejection |
| US5480895A (en) | 1991-09-27 | 1996-01-02 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Method of producing antibodies to a restricted population of T lymphocytes, antibodies produced therefrom and methods of use thereof |
| US5298386A (en) * | 1992-06-09 | 1994-03-29 | Eastman Kodak Company | In-line solvent incorporation for amorphous particle dispersions |
| US5545716A (en) | 1992-09-08 | 1996-08-13 | University Of Florida | Superantigen agonist and antagonist peptides |
| EP0688223A4 (en) | 1993-03-12 | 1998-05-13 | Cellcor Inc | -i (IN VITRO) 'ASSAY' FOR MEASURING THE DEGREE OF ACTIVATION OF IMMUNE CELLS |
| US5494899A (en) | 1993-04-07 | 1996-02-27 | Oklahoma Medical Research Foundation | Selective regulation of B lymphocyte precursors by hormones |
| WO1994026876A1 (en) | 1993-05-14 | 1994-11-24 | Dr. L. Willems-Instituut | Human t cell monoclone, process for its production and its use, diagnostic of infectious diseases, autoimmune diseases, t-cell mediated allergies and cancer |
| IL110787A0 (en) | 1993-08-27 | 1994-11-11 | Sandoz Ag | Biodegradable polymer, its preparation and pharmaceutical composition containing it |
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| US6096314A (en) | 1994-10-07 | 2000-08-01 | Yeda Research And Development Co. Ltd. | Peptides and pharmaceutical compositions comprising them |
| FR2727117A1 (fr) | 1994-11-18 | 1996-05-24 | Geffard Michel | Utilisation de conjugues de la polylysine pour la preparation de medicaments utiles dans le traitement des maladies neurodegeneratives et des affections degeneratives a caractere autoimmun |
| AU721898B2 (en) | 1994-11-18 | 2000-07-20 | Board Of Trustees Of The Leland Stanford Junior University | Methods for treatment of multiple sclerosis using peptide analogues at position 91 of human myelin basic protein |
| US6218166B1 (en) | 1994-12-09 | 2001-04-17 | John Wayne Cancer Institute | Adjuvant incorporation into antigen carrying cells: compositions and methods |
| US5874531A (en) | 1995-03-07 | 1999-02-23 | President And Fellows Of Harvard College | Identification of self and non-self antigens implicated autoimmune disease |
| US5869057A (en) | 1995-06-07 | 1999-02-09 | Rock; Edwin P. | Recombinant vaccines to break self-tolerance |
| SE9502921D0 (sv) | 1995-08-23 | 1995-08-23 | Astra Ab | New compounds |
| US5739307A (en) | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
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| US6130087A (en) | 1996-10-07 | 2000-10-10 | Fordham University | Methods for generating cytotoxic T cells in vitro |
| CN1237909A (zh) | 1996-10-11 | 1999-12-08 | 加利福尼亚大学董事会 | 联合使用肿瘤细胞与混合淋巴细胞的癌症免疫治疗 |
| US6054292A (en) | 1997-07-18 | 2000-04-25 | Incyte Pharmaceuticals, Inc. | T-cell receptor protein |
| US20020009448A1 (en) | 1997-09-19 | 2002-01-24 | Leslie P. Weiner | T-cell vaccination for the treatment of multiple sclerosis |
| US20020072493A1 (en) | 1998-05-19 | 2002-06-13 | Yeda Research And Development Co. Ltd. | Activated T cells, nervous system-specific antigens and their uses |
| WO2000014116A1 (en) | 1998-09-04 | 2000-03-16 | Baylor College Of Medicine | T cell peptides as therapeutics for immune-related disease |
| US6303314B1 (en) | 1999-02-23 | 2001-10-16 | Baylor College Of Medicine | T-cell receptor Vβ-Dβ-Jβ sequence and methods for its detection |
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| KR20030086983A (ko) | 2000-08-22 | 2003-11-12 | 베일러 칼리지 오브 메디신 | 티 세포 리셉터 브이 베타 - 디 베타 - 제이 베타 서열과그것을 검출하는 방법 |
| US7658926B2 (en) | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
| EP1444330A1 (en) | 2001-11-07 | 2004-08-11 | Kirin Beer Kabushiki Kaisha | Expansion of t cells in vitro and expanded t cell populations |
| DE10224223A1 (de) * | 2002-05-31 | 2003-12-11 | Mann & Hummel Filter | Filterelement, insbesondere zur Flüssigkeitsfilterung aus einem Gasstrom |
-
2001
- 2001-09-14 US US09/952,532 patent/US7658926B2/en not_active Expired - Fee Related
-
2002
- 2002-09-12 AU AU2002339914A patent/AU2002339914B2/en not_active Ceased
- 2002-09-12 RU RU2004103626/15A patent/RU2302257C2/ru not_active IP Right Cessation
- 2002-09-12 CN CN200710146971.7A patent/CN101229370B/zh not_active Expired - Fee Related
- 2002-09-12 MX MXPA04001862A patent/MXPA04001862A/es active IP Right Grant
- 2002-09-12 EP EP10178920A patent/EP2335720B1/en not_active Expired - Lifetime
- 2002-09-12 DE DE60226612T patent/DE60226612D1/de not_active Expired - Lifetime
- 2002-09-12 AT AT02778249T patent/ATE395076T1/de active
- 2002-09-12 HU HU0401519A patent/HUP0401519A3/hu unknown
- 2002-09-12 JP JP2003528491A patent/JP2005502721A/ja not_active Withdrawn
- 2002-09-12 PL PL367306A patent/PL210442B1/pl unknown
- 2002-09-12 DK DK10178920.4T patent/DK2335720T3/da active
- 2002-09-12 WO PCT/US2002/028874 patent/WO2003024393A2/en not_active Ceased
- 2002-09-12 DK DK02778249T patent/DK1416956T3/da active
- 2002-09-12 EP EP08004597.4A patent/EP1946767B1/en not_active Expired - Lifetime
- 2002-09-12 NZ NZ530762A patent/NZ530762A/en not_active IP Right Cessation
- 2002-09-12 EP EP02778249A patent/EP1416956B1/en not_active Expired - Lifetime
- 2002-09-12 ES ES02778249T patent/ES2306792T3/es not_active Expired - Lifetime
- 2002-09-12 PT PT101789204T patent/PT2335720E/pt unknown
- 2002-09-12 PT PT02778249T patent/PT1416956E/pt unknown
- 2002-09-12 BR BR0212504-8A patent/BR0212504A/pt not_active IP Right Cessation
- 2002-09-12 CA CA2459969A patent/CA2459969C/en not_active Expired - Fee Related
- 2002-09-12 CN CNB028176723A patent/CN100346824C/zh not_active Expired - Fee Related
- 2002-09-12 ES ES10178920T patent/ES2418529T3/es not_active Expired - Lifetime
- 2002-09-12 IL IL15999802A patent/IL159998A0/xx not_active IP Right Cessation
- 2002-09-12 KR KR10-2004-7002735A patent/KR20040066787A/ko not_active Ceased
-
2004
- 2004-02-24 ZA ZA2004/01502A patent/ZA200401502B/en unknown
-
2005
- 2005-02-17 US US11/060,848 patent/US20050186192A1/en not_active Abandoned
-
2007
- 2007-06-28 JP JP2007171303A patent/JP4889581B2/ja not_active Expired - Fee Related
-
2009
- 2009-02-04 IL IL196900A patent/IL196900A/en not_active IP Right Cessation
-
2011
- 2011-05-27 JP JP2011119771A patent/JP2011168618A/ja active Pending
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2014
- 2014-10-20 JP JP2014213513A patent/JP2015017129A/ja active Pending
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2016
- 2016-07-07 JP JP2016134760A patent/JP2016188238A/ja not_active Withdrawn
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