ATE309349T1 - Chemokinrezeptor 88c sowie dessen antikörper - Google Patents

Chemokinrezeptor 88c sowie dessen antikörper

Info

Publication number
ATE309349T1
ATE309349T1 AT96945669T AT96945669T ATE309349T1 AT E309349 T1 ATE309349 T1 AT E309349T1 AT 96945669 T AT96945669 T AT 96945669T AT 96945669 T AT96945669 T AT 96945669T AT E309349 T1 ATE309349 T1 AT E309349T1
Authority
AT
Austria
Prior art keywords
chemokine receptors
antibodies
modulators
ligands
chemokine receptor
Prior art date
Application number
AT96945669T
Other languages
English (en)
Inventor
Patrick W Gray
Vicki L Schweickart
Carol J Raport
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24302427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE309349(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE309349T1 publication Critical patent/ATE309349T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • AIDS & HIV (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96945669T 1995-12-20 1996-12-20 Chemokinrezeptor 88c sowie dessen antikörper ATE309349T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/575,967 US6265184B1 (en) 1995-12-20 1995-12-20 Polynucleotides encoding chemokine receptor 88C
US08/661,393 US6268477B1 (en) 1995-12-20 1996-06-07 Chemokine receptor 88-C
PCT/US1996/020759 WO1997022698A2 (en) 1995-12-20 1996-12-20 Chemokine receptors 88-2b[ckr-3] and 88c and their antibodies

Publications (1)

Publication Number Publication Date
ATE309349T1 true ATE309349T1 (de) 2005-11-15

Family

ID=24302427

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07013395T ATE458052T1 (de) 1995-12-20 1996-12-20 Verfahren zu chemokinrezeptor 88c
AT96945669T ATE309349T1 (de) 1995-12-20 1996-12-20 Chemokinrezeptor 88c sowie dessen antikörper

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT07013395T ATE458052T1 (de) 1995-12-20 1996-12-20 Verfahren zu chemokinrezeptor 88c

Country Status (17)

Country Link
US (7) US6265184B1 (de)
EP (3) EP1870465B1 (de)
JP (4) JP3288384B2 (de)
CN (2) CN1827646A (de)
AT (2) ATE458052T1 (de)
AU (1) AU730463B2 (de)
BR (1) BR9607300A (de)
CA (1) CA2213331C (de)
CZ (1) CZ261097A3 (de)
DE (2) DE69635406T3 (de)
DK (2) DK0811063T3 (de)
ES (2) ES2341371T3 (de)
HU (1) HUP9801127A3 (de)
NO (2) NO973800L (de)
PL (2) PL192294B1 (de)
SK (1) SK112897A3 (de)
WO (1) WO1997022698A2 (de)

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US20040151719A1 (en) * 1995-06-06 2004-08-05 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
US6025154A (en) * 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
ES2325042T3 (es) * 1995-06-07 2009-08-24 Progenics Pharmaceuticals, Inc. Anticuerpo monoclonal para inhibir la fusion de membrana mediada por glicoproteina de la envoltura de vih-1.
US7018627B1 (en) 1995-06-07 2006-03-28 Icos Corporation Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances, and uses thereof
US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
US7118859B2 (en) * 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
WO1997028258A1 (en) * 1996-01-30 1997-08-07 The National Institutes Of Health Cells expressing both human cd4 and cxcr4
DE69739366D1 (de) 1996-03-01 2009-05-28 Euroscreen Sa Aktive und inactive CC-Chemokinrezeptoren und Nukleinsäuremoleküle, die für diesen Rezeptor kodieren
US6344545B1 (en) * 1996-06-14 2002-02-05 Progenics Pharmaceuticals, Inc. Method for preventing HIV-1 infection of CD4+ cells
US7858298B1 (en) 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
EP0915969A4 (de) 1996-04-02 2002-04-17 Progenics Pharm Inc Unterdrückung der infektion von cd4+ zellen durch hiv
AU2813297A (en) * 1996-04-26 1997-11-19 Incyte Pharmaceuticals, Inc. Mammalian mixed lymphocyte receptors, chemokine receptors {mmlr-ccr}
EP1012190A4 (de) * 1996-04-26 2004-04-28 Merck & Co Inc Eotaxinrezeptor aus Eosinophilen
US6271347B1 (en) * 1996-04-26 2001-08-07 Merck & Co., Inc. Eosinophil eotaxin receptor
US5939320A (en) * 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
US6258527B1 (en) 1996-05-20 2001-07-10 The Aaron Diamond Aids Research Center Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
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US6057102A (en) * 1996-08-08 2000-05-02 The Aaron Diamond Aids Research Center HIV coreceptor mutants
US6388055B1 (en) 1996-10-03 2002-05-14 Smithkline Beecham Corporation Mouse CC-CKR5 receptor polypeptide
US6528625B1 (en) 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same
US6153431A (en) * 1997-05-30 2000-11-28 Fond Mondiale Rech & Prev Sida Human immunodeficiency virus co-receptor variants associated with resistance to virus infection
US6465237B1 (en) * 1997-07-01 2002-10-15 Millennium Pharmaceuticals, Inc. Cloning and characterization of a human adenylyl cyclase
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6204024B1 (en) * 1997-09-12 2001-03-20 Akzo Nobel N.V. CCR5 RNA transcription based amplification assay
US6287805B1 (en) 1998-03-20 2001-09-11 Millennium Pharmaceuticals, Inc. Nucleic acid molecules of the protein-coupled heptahelical receptor superfamily and uses therefor
CA2235420A1 (en) 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
US20080015348A1 (en) * 1998-12-16 2008-01-17 Progenics Pharmaceuticals, Inc. Nucleic acids encoding polypeptides of anti-CCR5 antibodies
US20040228869A1 (en) * 1998-12-16 2004-11-18 Progenics Pharmaceuticals, Inc. Synergistic inhibition of HIV-1 fusion and attachment, compositions and antibodies thereto
EP2386565A3 (de) 1999-01-12 2013-11-20 Cambridge Enterprise Ltd. Verbindungen und Verfahren zur Hemmung oder Verstärkung einer Entzündungsreaktion
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
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US6692922B2 (en) 2000-08-15 2004-02-17 The Board Of Trustees Of The Leland Stanford Junior University Method for identifying agents which modulate chemokine “MEC”-induced functions of CCR3
US7138119B2 (en) * 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7175988B2 (en) * 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
US7060273B2 (en) * 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US20030104496A1 (en) * 2001-11-30 2003-06-05 Cytokinetics, Inc. Novel motor protein of P. falciparum and methods for its use
US7393934B2 (en) * 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
US20050069549A1 (en) 2002-01-14 2005-03-31 William Herman Targeted ligands
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US7122185B2 (en) * 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
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ES2450929T3 (es) 2004-10-29 2014-03-25 Topigen Pharmaceuticals Inc. Oligonucleótidos antisentido para tratar la alergia y la proliferación de las células neoplásicas
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US5939320A (en) 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
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Also Published As

Publication number Publication date
JP3288384B2 (ja) 2002-06-04
CZ261097A3 (cs) 1998-06-17
US6268477B1 (en) 2001-07-31
JP2001264324A (ja) 2001-09-26
EP0811063A2 (de) 1997-12-10
DK0811063T3 (da) 2006-04-10
EP0811063B1 (de) 2005-11-09
CN1827646A (zh) 2006-09-06
HUP9801127A2 (hu) 1998-08-28
ES2255716T5 (es) 2014-03-21
EP1870465A2 (de) 2007-12-26
ES2255716T3 (es) 2006-07-01
PL192294B1 (pl) 2006-09-29
NO20052202D0 (no) 2005-05-04
EP1870465A3 (de) 2008-04-23
AU730463B2 (en) 2001-03-08
DE69635406D1 (de) 2005-12-15
NO973800D0 (no) 1997-08-19
US20040230037A1 (en) 2004-11-18
NO973800L (no) 1997-10-20
EP0811063B9 (de) 2014-04-23
CN1222617C (zh) 2005-10-12
HUP9801127A3 (en) 2000-12-28
DE69635406T2 (de) 2006-08-03
DE69638128D1 (de) 2010-04-01
ES2341371T3 (es) 2010-06-18
JP2001029089A (ja) 2001-02-06
US20020150888A1 (en) 2002-10-17
EP1642975A3 (de) 2006-04-12
NO20052202L (no) 1997-10-20
ATE458052T1 (de) 2010-03-15
AU1689297A (en) 1997-07-14
WO1997022698A2 (en) 1997-06-26
CA2213331C (en) 2011-09-27
JP2009065976A (ja) 2009-04-02
EP1642975A2 (de) 2006-04-05
CN1183805A (zh) 1998-06-03
MX9706316A (es) 1997-11-29
CA2213331A1 (en) 1997-06-26
PL192071B1 (pl) 2006-08-31
PL321937A1 (en) 1998-01-05
US7662548B2 (en) 2010-02-16
DE69635406T3 (de) 2014-04-24
DK1870465T3 (da) 2010-05-17
BR9607300A (pt) 1997-11-25
NO327506B1 (no) 2009-07-27
US6797811B1 (en) 2004-09-28
US20050260565A1 (en) 2005-11-24
US20080032336A1 (en) 2008-02-07
EP0811063B2 (de) 2013-12-04
EP1870465B1 (de) 2010-02-17
WO1997022698A3 (en) 1997-09-12
SK112897A3 (en) 1998-07-08
US6265184B1 (en) 2001-07-24
JPH11503028A (ja) 1999-03-23

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