IL158486A0 - Nociceptin analogs - Google Patents

Nociceptin analogs

Info

Publication number
IL158486A0
IL158486A0 IL15848602A IL15848602A IL158486A0 IL 158486 A0 IL158486 A0 IL 158486A0 IL 15848602 A IL15848602 A IL 15848602A IL 15848602 A IL15848602 A IL 15848602A IL 158486 A0 IL158486 A0 IL 158486A0
Authority
IL
Israel
Prior art keywords
nociceptin
analogs
nociceptin analogs
Prior art date
Application number
IL15848602A
Other languages
English (en)
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of IL158486A0 publication Critical patent/IL158486A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL15848602A 2001-04-18 2002-04-18 Nociceptin analogs IL158486A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28467401P 2001-04-18 2001-04-18
US28467601P 2001-04-18 2001-04-18
PCT/US2002/012356 WO2002085291A2 (en) 2001-04-18 2002-04-18 Nociceptin analogs

Publications (1)

Publication Number Publication Date
IL158486A0 true IL158486A0 (en) 2004-05-12

Family

ID=26962736

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15848602A IL158486A0 (en) 2001-04-18 2002-04-18 Nociceptin analogs
IL158486A IL158486A (en) 2001-04-18 2003-10-19 Nociceptin analogs

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL158486A IL158486A (en) 2001-04-18 2003-10-19 Nociceptin analogs

Country Status (14)

Country Link
US (3) US6861421B2 (ko)
EP (2) EP1379252A4 (ko)
JP (2) JP4380992B2 (ko)
KR (3) KR100855204B1 (ko)
CN (1) CN100441182C (ko)
AU (2) AU2002303406B2 (ko)
BR (1) BR0209128A (ko)
CA (1) CA2444108C (ko)
HK (1) HK1070573A1 (ko)
HU (1) HUP0402510A3 (ko)
IL (2) IL158486A0 (ko)
MX (1) MXPA03009602A (ko)
RU (1) RU2268883C2 (ko)
WO (1) WO2002085291A2 (ko)

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WO2003075929A1 (en) * 2002-03-13 2003-09-18 Janssen Pharmaceutica N.V. Inhibitors of histone deacetylase
PT1491212E (pt) 2002-03-29 2012-11-16 Mitsubishi Tanabe Pharma Corp Medicamento para distúrbios de sono
CL2007003590A1 (es) * 2006-12-12 2008-02-29 Wyeth Corp Compuestos derivados de aril sulfamida; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en prevencion y tratamiento de sintomas vasomotrices, disfuncion sexual, transtornos gastrointestinales, transt
WO2008073958A2 (en) 2006-12-12 2008-06-19 Wyeth Substituted benzothiadiazinedioxide derivatives and methods of their use
DE602008002690D1 (de) * 2007-01-16 2010-11-04 Purdue Pharma Lp Heterozyklische substituierte piperidine als orl-1-liganden
RU2488585C2 (ru) * 2007-08-31 2013-07-27 Пэдью Фарма Л.П. Замещенные пиперидиновые соединения хиноксалинового типа и их применение
AR072578A1 (es) 2008-07-21 2010-09-08 Purdue Pharma Lp Compuestos de piperidina puenteada tipo quinoxalina sustituida y los usos de los mismos
JP5872585B2 (ja) * 2010-12-22 2016-03-01 パーデュー、ファーマ、リミテッド、パートナーシップ リン置換キノキサリンタイプピペリジン化合物とその使用
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014102589A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
CA2896871A1 (en) * 2012-12-31 2014-07-03 Kerry L. Spear Heterocyclic compounds and methods of use thereof
AR107358A1 (es) 2016-01-13 2018-04-25 Gruenenthal Gmbh Derivados de 3-(carboximetil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano
DK3402783T3 (da) 2016-01-13 2020-05-04 Gruenenthal Gmbh 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decan-derivater
ES2797904T3 (es) 2016-01-13 2020-12-04 Gruenenthal Gmbh Derivados de 3-((hetero)aril)alquil-8-amino-2-oxo-1,3-diazaespiro-[4.5]-decano
RS60307B1 (sr) 2016-01-13 2020-07-31 Gruenenthal Gmbh Derivati 3-((hetero-)aril)-8-amino-2-okso-1,3-diaza-spiro-[4.5]-dekana
RS60855B1 (sr) 2016-01-13 2020-10-30 Gruenenthal Gmbh Derivati 8-amino-2-okso-1,3-diaza-spiro-[4.5]-dekana

Family Cites Families (39)

* Cited by examiner, † Cited by third party
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US3318900A (en) 1964-05-06 1967-05-09 Janssen Pharmaceutica Nv Derivatives of benzimidazolinyl piperidine
US3325499A (en) 1964-11-02 1967-06-13 Mcneilab Inc 1-(1-hydrocarbyl-4-piperdyl)-2-indolinone
DE2609645A1 (de) 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE3066434D1 (en) * 1979-11-21 1984-03-08 Kyowa Hakko Kogyo Kk Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them
US4344945A (en) * 1980-03-10 1982-08-17 Kyowa Hakko Kogyo Co., Ltd. Piperidine derivatives
US4329353A (en) 1980-10-22 1982-05-11 Janssen Pharmaceutica, N.V. 1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
US4410528A (en) 1980-05-16 1983-10-18 Kyowa Hakko Kogyo Co., Ltd. Hypotensive piperidine derivatives
JPS5759889A (en) * 1980-09-30 1982-04-10 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS58180481A (ja) 1982-04-15 1983-10-21 Kyowa Hakko Kogyo Co Ltd 新規なピペリジン誘導体
JPS60120872A (ja) * 1983-12-01 1985-06-28 Kyowa Hakko Kogyo Co Ltd 新規なヘテロ環状化合物及び強心剤
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WO1995019773A1 (en) * 1992-10-07 1995-07-27 Merck & Co., Inc. Carbostyril oxytocin receptor antagonists
CA2166975C (en) * 1993-07-16 2005-04-05 Mark G. Bock Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists
WO1995028397A1 (en) * 1994-04-14 1995-10-26 Merck & Co., Inc. Alpha1c adrenergic receptor antagonists
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US5767118A (en) * 1994-10-26 1998-06-16 Merck & Co., Inc. 4-Heterocyclic peperidines promote release of growth hormone
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US6166209A (en) 1997-12-11 2000-12-26 Hoffmann-La Roche Inc. Piperidine derivatives
IL137149A0 (en) 1998-01-19 2001-07-24 Pfizer 4-(2-keto-1-benzimidazolinyl) piperidine compounds as orl1-receptor agonists
RU2202344C2 (ru) 1998-03-26 2003-04-20 Джапан Тобакко Инк. Антагонисты ноцицептина, производные амида, аналгетик, способ инициирования антагонистического действия к ноцицептину, способ лечения боли, фармацевтические композиции
AU3809999A (en) 1998-05-18 1999-12-06 Novo Nordisk A/S Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
ID29137A (id) 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
MA26659A1 (fr) 1998-08-06 2004-12-20 Pfizer Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
JP2001044213A (ja) * 1999-07-30 2001-02-16 Hitachi Cable Ltd ヘテロバイポーラトランジスタ用エピタキシャルウエハ
SE9904652D0 (sv) * 1999-12-17 1999-12-17 Astra Pharma Prod Novel Compounds
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RU2317988C2 (ru) * 2000-08-14 2008-02-27 Орто-Макнейл Фармасьютикал, Инк. Замещенные пиразолы, фармацевтическая композиция на их основе, применение фармацевтической композиции и способ ингибирования активности катепсина s
JP2004531456A (ja) * 2000-09-06 2004-10-14 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 置換ピラゾールを用いてアレルギーを治療する方法
JP2007009500A (ja) * 2005-06-30 2007-01-18 Nissei Ltd パズル循環式駐車設備の運転方法

Also Published As

Publication number Publication date
RU2003133454A (ru) 2005-05-27
KR100722207B1 (ko) 2007-05-29
US20050148580A1 (en) 2005-07-07
CA2444108A1 (en) 2002-10-31
CA2444108C (en) 2012-07-24
EP1997818A3 (en) 2009-04-08
KR100855204B1 (ko) 2008-09-01
KR20030096326A (ko) 2003-12-24
JP2005506302A (ja) 2005-03-03
KR20060129103A (ko) 2006-12-14
HUP0402510A3 (en) 2012-08-28
WO2002085291A2 (en) 2002-10-31
IL158486A (en) 2010-11-30
KR20050118315A (ko) 2005-12-16
US6861421B2 (en) 2005-03-01
US7563809B2 (en) 2009-07-21
EP1379252A4 (en) 2005-11-02
KR100729242B1 (ko) 2007-06-15
EP1997818A2 (en) 2008-12-03
AU2006202794A1 (en) 2006-07-20
BR0209128A (pt) 2005-11-01
CN1568188A (zh) 2005-01-19
JP2009280603A (ja) 2009-12-03
HK1070573A1 (en) 2005-06-24
US20030013874A1 (en) 2003-01-16
CN100441182C (zh) 2008-12-10
EP1379252A2 (en) 2004-01-14
AU2002303406B2 (en) 2006-03-30
HUP0402510A2 (hu) 2005-04-28
JP4380992B2 (ja) 2009-12-09
RU2268883C2 (ru) 2006-01-27
US20090253727A1 (en) 2009-10-08
WO2002085291A3 (en) 2003-02-20
MXPA03009602A (es) 2004-04-02

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