HK1070573A1 - Nociceptin compounds - Google Patents

Nociceptin compounds

Info

Publication number
HK1070573A1
HK1070573A1 HK05103227.4A HK05103227A HK1070573A1 HK 1070573 A1 HK1070573 A1 HK 1070573A1 HK 05103227 A HK05103227 A HK 05103227A HK 1070573 A1 HK1070573 A1 HK 1070573A1
Authority
HK
Hong Kong
Prior art keywords
nociceptin
compounds
nociceptin compounds
Prior art date
Application number
HK05103227.4A
Other languages
English (en)
Inventor
Richard R Goehring
Zhengming Chen
Donald Kyle
Sam Victory
Parviz Gharagozloo
John Whitehead
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of HK1070573A1 publication Critical patent/HK1070573A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK05103227.4A 2001-04-18 2005-04-15 Nociceptin compounds HK1070573A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28467601P 2001-04-18 2001-04-18
US28467401P 2001-04-18 2001-04-18
PCT/US2002/012356 WO2002085291A2 (en) 2001-04-18 2002-04-18 Nociceptin analogs

Publications (1)

Publication Number Publication Date
HK1070573A1 true HK1070573A1 (en) 2005-06-24

Family

ID=26962736

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103227.4A HK1070573A1 (en) 2001-04-18 2005-04-15 Nociceptin compounds

Country Status (14)

Country Link
US (3) US6861421B2 (xx)
EP (2) EP1379252A4 (xx)
JP (2) JP4380992B2 (xx)
KR (3) KR100855204B1 (xx)
CN (1) CN100441182C (xx)
AU (2) AU2002303406B2 (xx)
BR (1) BR0209128A (xx)
CA (1) CA2444108C (xx)
HK (1) HK1070573A1 (xx)
HU (1) HUP0402510A3 (xx)
IL (2) IL158486A0 (xx)
MX (1) MXPA03009602A (xx)
RU (1) RU2268883C2 (xx)
WO (1) WO2002085291A2 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212089B1 (pl) * 2002-03-13 2012-08-31 Janssen Pharmaceutica Nv Związki heterocykliczne jako inhibitory deacetylazy histonowej, kompozycja farmaceutyczna je zawierająca, ich zastosowanie, sposób wytwarzania, sposób wykrywania lub identyfikacji HDAC oraz kompozycja
DK1491212T3 (da) 2002-03-29 2012-10-29 Mitsubishi Tanabe Pharma Corp Middel til behandling af søvnforstyrrelser
CL2007003590A1 (es) * 2006-12-12 2008-02-29 Wyeth Corp Compuestos derivados de aril sulfamida; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en prevencion y tratamiento de sintomas vasomotrices, disfuncion sexual, transtornos gastrointestinales, transt
US7718652B2 (en) 2006-12-12 2010-05-18 Wyeth Llc Substituted benzothiadiazinedioxide derivatives and methods of their use
SI2076506T1 (sl) * 2007-01-16 2011-01-31 Purdue Pharma Lp Heterociklično substituirani piperidini kot ORL-1 ligandi
EP3101018B1 (en) * 2007-08-31 2019-03-06 Purdue Pharma L.P. Substituted-quinoxaline-type-piperidine compounds and the uses thereof
EP2324013B3 (en) 2008-07-21 2014-10-22 Purdue Pharma LP Substituted-quinoxaline-type bridged-piperidine compounds and the uses thereof
US9598447B2 (en) 2010-12-22 2017-03-21 Purdue Pharma L.P. Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
WO2014102590A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
EP2938341B1 (en) * 2012-12-31 2018-09-05 Sunovion Pharmaceuticals Inc. Heterocyclic compounds and methods of use thereof
BR112018014302B1 (pt) 2016-01-13 2023-10-17 Grünenthal GmbH Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano
EA034898B1 (ru) 2016-01-13 2020-04-03 Грюненталь Гмбх Производные 8-амино-2-оксо-1,3-диазаспиро[4,5]декана
AU2017206908B2 (en) 2016-01-13 2020-07-09 Grünenthal GmbH 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
MX2018008644A (es) 2016-01-13 2018-11-19 Gruenenthal Gmbh Derivados de 3-((hetero)aril)-alquil-8-amino-2-oxo-1,3-diaza-espir o-[4.5]-decano.
TWI640514B (zh) 2016-01-13 2018-11-11 歌林達有限公司 ３－（羧甲基）－８－胺基－２－側氧基－１，３－二氮－螺－［４．５］－癸烷衍生物

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161645A (en) 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
US3318900A (en) 1964-05-06 1967-05-09 Janssen Pharmaceutica Nv Derivatives of benzimidazolinyl piperidine
US3325499A (en) 1964-11-02 1967-06-13 Mcneilab Inc 1-(1-hydrocarbyl-4-piperdyl)-2-indolinone
DE2609645A1 (de) 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
EP0029707B1 (en) * 1979-11-21 1984-02-01 Kyowa Hakko Kogyo Co., Ltd Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them
US4344945A (en) * 1980-03-10 1982-08-17 Kyowa Hakko Kogyo Co., Ltd. Piperidine derivatives
US4329353A (en) 1980-10-22 1982-05-11 Janssen Pharmaceutica, N.V. 1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
US4410528A (en) 1980-05-16 1983-10-18 Kyowa Hakko Kogyo Co., Ltd. Hypotensive piperidine derivatives
JPS5759889A (en) * 1980-09-30 1982-04-10 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS58180481A (ja) 1982-04-15 1983-10-21 Kyowa Hakko Kogyo Co Ltd 新規なピペリジン誘導体
JPS60120872A (ja) * 1983-12-01 1985-06-28 Kyowa Hakko Kogyo Co Ltd 新規なヘテロ環状化合物及び強心剤
DE69009785T2 (de) * 1989-02-10 1994-11-03 Otsuka Pharma Co Ltd Carbostyrilderivate.
WO1995019773A1 (en) * 1992-10-07 1995-07-27 Merck & Co., Inc. Carbostyril oxytocin receptor antagonists
CA2166975C (en) * 1993-07-16 2005-04-05 Mark G. Bock Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists
CA2187767A1 (en) * 1994-04-14 1995-10-26 Joel R. Huff Alpha1c adrenergic receptor antagonists
FR2722190B1 (fr) 1994-07-05 1996-10-04 Sanofi Sa Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
US5767118A (en) * 1994-10-26 1998-06-16 Merck & Co., Inc. 4-Heterocyclic peperidines promote release of growth hormone
US5574044A (en) 1994-10-27 1996-11-12 Merck & Co., Inc. Muscarine antagonists
ES2247604T3 (es) 1995-06-12 2006-03-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de ciclooxigenasa-2 y un inhibidor de 5-lipoxigenasa.
DE69621469T2 (de) 1995-09-13 2002-12-12 Kyowa Hakko Kogyo Co., Ltd. Phenylpiperidin-derivate
WO1997040035A1 (en) 1996-04-19 1997-10-30 Neurosearch A/S 1-(4-piperidyl)-benzimidazoles having neurotrophic activity
US6063796A (en) * 1997-04-04 2000-05-16 Merck & Co., Inc. Somatostatin agonists
WO1998054168A1 (fr) 1997-05-30 1998-12-03 Banyu Pharmaceutical Co., Ltd. Derives de 2-0xoimidazole
JPH10330377A (ja) 1997-06-02 1998-12-15 Kyowa Hakko Kogyo Co Ltd ピペリジン誘導体
US6166037A (en) 1997-08-28 2000-12-26 Merck & Co., Inc. Pyrrolidine and piperidine modulators of chemokine receptor activity
SI0921125T1 (en) 1997-12-05 2002-04-30 F. Hoffmann-La Roche Ag 1,3,8-Triazaspiro(4,5)decan-4-on derivatives
US6166209A (en) 1997-12-11 2000-12-26 Hoffmann-La Roche Inc. Piperidine derivatives
PT1049689E (pt) 1998-01-19 2002-09-30 Pfizer Compostos de 4-(2-ceto-1-benzimidazolinil)piperidina como agonistas do receptor orl1
US6410561B1 (en) 1998-03-26 2002-06-25 Japan Tobacco Inc. Amide derivatives and nociceptin antagonists
EP1080091A1 (en) 1998-05-18 2001-03-07 Novo Nordisk A/S Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
ID29137A (id) 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
MA26659A1 (fr) 1998-08-06 2004-12-20 Pfizer Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
JP2001044213A (ja) * 1999-07-30 2001-02-16 Hitachi Cable Ltd ヘテロバイポーラトランジスタ用エピタキシャルウエハ
SE9904652D0 (sv) * 1999-12-17 1999-12-17 Astra Pharma Prod Novel Compounds
ATE302184T1 (de) 2000-02-18 2005-09-15 Meiji Seika Kaisha Phenoxyalkylaminderivate als agonisten des opioid-delta rezeptors
ES2261463T3 (es) * 2000-08-14 2006-11-16 Ortho-Mcneil Pharmaceutical, Inc. Pirazoles sustituidos.
AU8870601A (en) 2000-09-06 2002-03-22 Ortho Mcneil Pharm Inc A method for treating allergies using substituted pyrazoles
JP2007009500A (ja) * 2005-06-30 2007-01-18 Nissei Ltd パズル循環式駐車設備の運転方法

Also Published As

Publication number Publication date
AU2006202794A1 (en) 2006-07-20
EP1379252A2 (en) 2004-01-14
KR20030096326A (ko) 2003-12-24
WO2002085291A2 (en) 2002-10-31
BR0209128A (pt) 2005-11-01
CN1568188A (zh) 2005-01-19
JP2009280603A (ja) 2009-12-03
IL158486A (en) 2010-11-30
JP2005506302A (ja) 2005-03-03
HUP0402510A3 (en) 2012-08-28
EP1997818A2 (en) 2008-12-03
US20050148580A1 (en) 2005-07-07
KR20050118315A (ko) 2005-12-16
JP4380992B2 (ja) 2009-12-09
KR20060129103A (ko) 2006-12-14
AU2002303406B2 (en) 2006-03-30
CA2444108C (en) 2012-07-24
RU2003133454A (ru) 2005-05-27
KR100729242B1 (ko) 2007-06-15
HUP0402510A2 (hu) 2005-04-28
RU2268883C2 (ru) 2006-01-27
EP1379252A4 (en) 2005-11-02
MXPA03009602A (es) 2004-04-02
KR100722207B1 (ko) 2007-05-29
KR100855204B1 (ko) 2008-09-01
US20090253727A1 (en) 2009-10-08
EP1997818A3 (en) 2009-04-08
CN100441182C (zh) 2008-12-10
US7563809B2 (en) 2009-07-21
US6861421B2 (en) 2005-03-01
WO2002085291A3 (en) 2003-02-20
CA2444108A1 (en) 2002-10-31
IL158486A0 (en) 2004-05-12
US20030013874A1 (en) 2003-01-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140418