IL158316A0 - Therapeutic and diagnostic uses of antibody specificity profiles - Google Patents

Therapeutic and diagnostic uses of antibody specificity profiles

Info

Publication number
IL158316A0
IL158316A0 IL15831602A IL15831602A IL158316A0 IL 158316 A0 IL158316 A0 IL 158316A0 IL 15831602 A IL15831602 A IL 15831602A IL 15831602 A IL15831602 A IL 15831602A IL 158316 A0 IL158316 A0 IL 158316A0
Authority
IL
Israel
Prior art keywords
therapeutic
antibody specificity
diagnostic uses
specificity profiles
profiles
Prior art date
Application number
IL15831602A
Other languages
English (en)
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of IL158316A0 publication Critical patent/IL158316A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Rehabilitation Therapy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
IL15831602A 2001-04-10 2002-04-10 Therapeutic and diagnostic uses of antibody specificity profiles IL158316A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28309001P 2001-04-10 2001-04-10
PCT/US2002/011356 WO2002084249A2 (en) 2001-04-10 2002-04-10 Therapeutic and diagnostic uses of antibody specificity profiles

Publications (1)

Publication Number Publication Date
IL158316A0 true IL158316A0 (en) 2004-05-12

Family

ID=23084463

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15831602A IL158316A0 (en) 2001-04-10 2002-04-10 Therapeutic and diagnostic uses of antibody specificity profiles

Country Status (8)

Country Link
US (2) US7785819B2 (https=)
EP (3) EP2302387A1 (https=)
JP (2) JP4594588B2 (https=)
CN (1) CN100405062C (https=)
AU (1) AU2002256168B2 (https=)
CA (1) CA2443777A1 (https=)
IL (1) IL158316A0 (https=)
WO (1) WO2002084249A2 (https=)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391550B1 (en) 1996-09-19 2002-05-21 Affymetrix, Inc. Identification of molecular sequence signatures and methods involving the same
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
US6994966B2 (en) 2000-02-17 2006-02-07 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
IL137460A0 (en) * 2000-07-24 2001-07-24 Yeda Res & Dev Identifying antigen clusters for monitoring a global state of an immune system
US20060275851A1 (en) * 2000-07-26 2006-12-07 Emmert-Buck Michael R Layered peptide/antigen arrays - for high-throughput antibody screening of clinical samples
US20020155618A1 (en) * 2001-01-17 2002-10-24 O'hagan David Methods of analyzing and sorting one or more analytes
DE10127572A1 (de) * 2001-05-30 2002-12-05 Pathoarray Gmbh Werkzeuge zur Diagnostik, molekularen Definition und Therapieentwicklung chronischer entzündlicher Gelenkerkrankungen
US7863004B2 (en) * 2001-12-04 2011-01-04 Wayne State University Neoepitope detection of disease using protein arrays
US20090149335A1 (en) * 2002-02-22 2009-06-11 Biolife Solutions Inc. Method and use of microarray technology and proteogenomic analysis to predict efficacy of human and xenographic cell, tissue and organ transplant
US20030232396A1 (en) * 2002-02-22 2003-12-18 Biolife Solutions, Inc. Method and use of protein microarray technology and proteomic analysis to determine efficacy of human and xenographic cell, tissue and organ transplant
CN1164948C (zh) * 2002-06-06 2004-09-01 成都夸常科技有限公司 一种基于抗原抗体反应的试剂盒
JP4269064B2 (ja) * 2003-02-26 2009-05-27 国立大学法人 千葉大学 重症筋無力症の検査方法及びそのための検査薬
DE10332848B4 (de) * 2003-07-18 2012-10-11 Henkel Ag & Co. Kgaa Mikroarrays immobilisierter Biomoleküle, deren Herstellung und Verwendung
MXPA06002134A (es) * 2003-08-29 2006-05-31 Genentech Inc Terapia de trastornos oculares.
TWI242644B (en) * 2003-12-03 2005-11-01 Ind Tech Res Inst Method for screening autoantigen
CA2555199A1 (en) * 2004-02-04 2005-08-18 Yokohama City University Peptidylarginine deiminase 4 inhibitor
EP1564556A1 (de) 2004-02-17 2005-08-17 DST Diagnostic Science & Technology GmbH Verfahren und Vorrichtung zur Bestimmung mehrerer Analyten mit simultaner interner Kontrolle
WO2005114203A2 (en) * 2004-05-20 2005-12-01 The Regents Of The University Of California Dominant b cell epitopes and methods of making and using thereof
US7799556B2 (en) * 2004-06-17 2010-09-21 George Dacai Liu System and method for antigen structure-independent detection of antigens captured on antibody arrays
US20060263837A1 (en) * 2004-06-17 2006-11-23 Liu George D Immunoassay system and method for detection of antigens
CA2513317A1 (en) * 2004-07-06 2006-01-06 Kuhnil Pharmaceutical Co., Ltd. Composition for the diagnosis of retinal vascular disease comprising aldolase and method for diagnosis using it
US20060269963A1 (en) * 2004-07-08 2006-11-30 Yang-Je Cho Composition for the diagnosis of retinal vascular disease comprising aldolase and method for diagnosis using it
CN101160524A (zh) * 2005-02-24 2008-04-09 西米尼斯公司 用于生物样品分类的组合物和方法
WO2006124644A2 (en) * 2005-05-12 2006-11-23 Board Of Regents, The University Of Texas System Protein and antibody profiling using small molecule microarrays
US20060286548A1 (en) * 2005-06-16 2006-12-21 Gregory Liposky Method of making recombinant human antibodies for use in biosensor technology
US8252775B2 (en) * 2005-07-21 2012-08-28 The Board Of Trustees Of The Leland Stanford Junior University Method of treating multiple sclerosis with phosphocholine containing lipids
AU2006287336A1 (en) * 2005-09-09 2007-03-15 The University Of Chicago Methods and compositions for diagnosis and immunotherapy of pollen allergy
JP4283812B2 (ja) * 2006-01-06 2009-06-24 財団法人工業技術研究院 重症筋無力症の診断方法およびそのキット
US7868139B2 (en) * 2006-01-24 2011-01-11 Uab Research Foundation Compositions and methods for the identification and treatment of immune-mediated inflammatory diseases
WO2007123976A2 (en) * 2006-04-18 2007-11-01 The Board Of Trustees Of The Leland Stanford Junior University Antibody profiling for determination of patient responsiveness
EP2015852A2 (en) * 2006-04-28 2009-01-21 Lane Ekberg Pivoting footwear systems and, configurable traction systems
GB0609119D0 (en) 2006-05-09 2006-06-21 Univ Birmingham Histones
US20080103057A1 (en) * 2006-08-23 2008-05-01 Utz Paul J Method for multi-color fab labeling of antibodies in a complex sample
WO2008111281A1 (ja) * 2007-03-12 2008-09-18 The University Of Tokushima アレルギー疾患の判定方法
ES2307421B1 (es) * 2007-04-30 2009-09-28 Consejo Superiorde Investigaciones Cientificas (Csic) Polipeptido quimerico fibrina-filagrina citruinado capaz de detectar los anticuerpos generados en la artritis reumatoide.
EP2158326B1 (en) * 2007-06-21 2012-06-20 The Board of Trustees of The Leland Stanford Junior University Biomarkers for rheumatoid arthritis
WO2009020058A1 (ja) * 2007-08-03 2009-02-12 Keio University 脱髄病変へのドラッグデリバリーシステム及び脱髄病変の生化学的マーカー
EP2353004B1 (en) 2008-11-12 2018-01-03 Yeda Research and Development Co. Ltd. Diagnosis of multiple sclerosis
EP2435827A1 (en) * 2009-05-29 2012-04-04 The Board of Regents of The University of Texas System Peptoid ligands for isolation and treatment of autoimmune t-cells
CA2764153C (en) * 2009-06-02 2021-07-27 The Board Of Regents Of The University Of Texas System Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
EP2461818B1 (en) 2009-08-03 2018-10-17 Incube Labs, Llc Swallowable capsule and method for stimulating incretin production within the intestinal tract
US9140701B2 (en) * 2009-08-18 2015-09-22 The Board Of Trustees Of The Leland Stanford Junior University Fibrinogen immune complexes to diagnose and guide therapy in rheumatoid arthritis
AU2010303304A1 (en) * 2009-10-08 2012-05-17 President And Fellows Of Harvard College Methods and compositions for amelioration of autoimmune disease using fusion proteins of anti-dendritic cell receptor antibody to peptide sequences
US8759259B2 (en) * 2009-10-16 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for producing cyclic peptoid libraries
US8759284B2 (en) 2009-12-24 2014-06-24 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
WO2011085081A2 (en) * 2010-01-08 2011-07-14 Bayhill Therapeutics, Inc. Methods of selecting ms patients for antigen specific therapy
US20110243993A1 (en) * 2010-03-29 2011-10-06 Broo Kerstin S Method for diagnosing and creating immunogenic tolerance in contact allergy and other epithelial immunotoxicological ailments
JP2011209224A (ja) * 2010-03-30 2011-10-20 Fujita Gakuen 抗原検索法及び抗体検出法
US20130310266A1 (en) * 2010-09-03 2013-11-21 Immport Therapeutics, Inc. Methods and Compositions For The Diagnosis And Treatment Of Cancer and Autoimmune Disorders
US8809269B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9402806B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8846040B2 (en) 2010-12-23 2014-09-30 Rani Therapeutics, Llc Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9629799B2 (en) 2010-12-23 2017-04-25 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8969293B2 (en) 2010-12-23 2015-03-03 Rani Therapeutics, Llc Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8980822B2 (en) 2010-12-23 2015-03-17 Rani Therapeutics, Llc Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9284367B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9861683B2 (en) 2010-12-23 2018-01-09 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9402807B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9283179B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10639272B2 (en) 2010-12-23 2020-05-05 Rani Therapeutics, Llc Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device
US9946836B2 (en) 2011-01-31 2018-04-17 Robert Bosch Gmbh Biomarker monitoring device and method
JP5565784B2 (ja) * 2011-04-22 2014-08-06 国立大学法人京都大学 関節リウマチの新規遺伝因子としてのミエリン塩基性蛋白の利用
WO2013077864A1 (en) 2011-11-22 2013-05-30 Robert Bosch Gmbh Method for self-referenced confidence test
US8852873B2 (en) 2012-04-13 2014-10-07 Diabetomics, Llc Maternal biomarkers for gestational diabetes
US20160025744A1 (en) * 2013-03-14 2016-01-28 The Board Of Trustees Of The Leland Stanford Junior University Plasmonic substrate for multiplex assessment of type 1 diabetes
US10545144B2 (en) 2013-12-31 2020-01-28 Yeda Research And Development Co., Ltd. Diagnosis of systemic lupus erythematosus using oligonucleotides antigens
EP3265814B1 (en) 2015-03-01 2020-11-18 Immunarray Ltd. Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens
US10564152B2 (en) * 2015-09-01 2020-02-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method and device for detecting antigen-specific antibodies in a biological fluid sample by using neodymium magnets
US10261076B2 (en) 2015-10-02 2019-04-16 The Board Of Trustees Of The Leland Stanford Junior University Method for detecting small molecule analytes using magnetoresistant sensors
WO2017223117A1 (en) 2016-06-20 2017-12-28 Healthtell Inc. Methods for diagnosis and treatment of autoimmune diseases
AU2017281039A1 (en) 2016-06-20 2019-01-24 Healthtell Inc. Methods for differential diagnosis of autoimmune diseases
JP6816876B2 (ja) * 2016-11-11 2021-01-20 国立大学法人富山大学 Ｒｏ５２／ＴＲＩＭ２１タンパク質に対する自己抗体が認識するエピトープおよびその利用
AU2017357818A1 (en) 2016-11-11 2019-05-30 HealthTell, Inc. Methods for identifying candidate biomarkers
KR20200031613A (ko) * 2017-06-19 2020-03-24 헬스텔 인크. 감별 진단을 위한 면역서명
US20200191785A1 (en) * 2018-12-18 2020-06-18 Euroimmun Medizinische Labordiagnostika Ag Method for Diagnosing Autoimmune Gastritis
DE202020006093U1 (de) * 2019-05-06 2025-04-09 The Regents Of The University Of California Nicht-HLA-Marker der Transplantatabstoßung
WO2021158533A1 (en) * 2020-02-06 2021-08-12 Arizona Board Of Regents On Behalf Of Arizona State University Transformational immune diagnostics
JP2024064128A (ja) * 2022-10-27 2024-05-14 チューニングフォーク・バイオ・インク 抗原探索方法及び抗原探索システム

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136160A (en) * 1977-08-17 1979-01-23 Cohen Steven R Specific assay for active demyelinization
DE3269567D1 (en) 1981-04-29 1986-04-10 Ciba Geigy Ag New devices and kits for immunological analysis
US4865970A (en) * 1986-02-28 1989-09-12 Hoffmann-La Roche Inc. Method of detecting ribosomal protein antibodies in systemic lupus erythematosus
US4880750A (en) * 1987-07-09 1989-11-14 Miragen, Inc. Individual-specific antibody identification methods
NL8703107A (nl) * 1987-12-22 1989-07-17 Nederlanden Staat Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten.
US6207645B1 (en) * 1989-03-21 2001-03-27 The Immune Response Corporation Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations
US6897287B1 (en) 1990-01-31 2005-05-24 Oklahoma Medical Research Foundation Ro/SSA peptide reagents for diagnosis of autoantibodies
EP0514458A1 (en) 1990-01-31 1992-11-25 The Board of Regents for the University of Oklahoma Assays and treatments for autoimmune diseases
US5674978A (en) * 1990-09-21 1997-10-07 The Regents Of The University Of California Peptides derived from glutamic acid decarboxylase
US5656272A (en) * 1991-03-18 1997-08-12 New York University Medical Center Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
US5674692A (en) * 1991-09-06 1997-10-07 Baekkeskov; Steinunn Methods for diabetes susceptibility assessment in asymptomatic patients
US6252040B1 (en) * 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US5578496A (en) * 1991-12-19 1996-11-26 Board Of Regents, Baylor College Of Medicine Detection of autoantibodies associated with the disease myasthenia gravis
DK0640101T3 (da) 1992-04-13 2000-05-15 Oklahoma Med Res Found Fremgangsmåder og reagenser til diagnosticering af autoantistoffer
US5200318A (en) 1992-05-13 1993-04-06 Miles Inc. Diagnosis of IDDM with a panel of immunoreagents
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
UA48150C2 (uk) * 1994-11-02 2002-08-15 Ай-Сі-Ен Фармасьютикалз Похідні амінокислот або аміноспиртів, олігонуклеотид
US5637545A (en) * 1994-12-21 1997-06-10 Uop Metallo manganese oxides
US6232088B1 (en) * 1995-02-08 2001-05-15 Phairson Medical, Inc. Treatment and prevention of immune rejection reactions
US5747035A (en) * 1995-04-14 1998-05-05 Genentech, Inc. Polypeptides with increased half-life for use in treating disorders involving the LFA-1 receptor
WO1997007211A1 (en) * 1995-08-11 1997-02-27 THE GOVERNMENT OF THE UNITED STATES, represented by THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES Materials and methods for detection and treatment of insulin-dependent diabetes
WO1997014028A2 (en) 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
EP0874901A2 (en) * 1995-12-20 1998-11-04 Institute of Molecular and Cell Biology Diagnostic reagents relating to diabetes
AU1989097A (en) * 1996-03-06 1997-09-22 University Of Washington Diabetes mellitus 37 kd autoantigen protein-tyrosine phosphatase
ATE233102T1 (de) * 1996-05-15 2003-03-15 Altarex Inc Verfahren und zusammensetzung zur umgestaltung multi-epitopischer antigene um die immunantwort einzuleiten
US5750356A (en) * 1996-05-31 1998-05-12 Anergen, Inc. Method for monitoring T cell reactivity
DE69724974T2 (de) * 1996-07-15 2004-05-19 Fujisawa Pharmaceutical Co., Ltd. Funktionelle natriumchloridzusammensetzungen
US6183988B1 (en) * 1996-10-02 2001-02-06 The General Hospital Corporation Leukocyte-specific protein and gene, and methods of use thereof
US6544523B1 (en) * 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
US6022697A (en) * 1996-11-29 2000-02-08 The Regents Of The University Of California Methods for the diagnosis and treatment of insulin-dependent diabetes mellitus
US5763158A (en) * 1997-02-06 1998-06-09 The United States Of America As Represented By The Secretary Of The Army Detection of multiple antigens or antibodies
CA2319828A1 (en) 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
US6770460B1 (en) * 1998-01-29 2004-08-03 Wallac Oy Fusion protein and its use in an immunoassay for the simultaneous detection of autoantibodies related to insulin-dependent diabetes mellitus
US6287874B1 (en) * 1998-02-02 2001-09-11 Signature Bioscience, Inc. Methods for analyzing protein binding events
CN1231761C (zh) 1998-12-23 2005-12-14 梅德塞克股份有限公司 一种检测装置及鉴定分子的方法
IL130586A0 (en) * 1999-06-21 2000-06-01 Yeda Res & Dev IL6RIL6 chimera for the treatment of demyelinating diseases
US6995237B1 (en) * 1999-10-27 2006-02-07 Cel-Sci Corporation Preparation and composition of peptides useful for treatment of autoimmune and transplant related graft versus host conditions
CN1274085A (zh) * 2000-04-13 2000-11-22 陈学银 一种蛋白芯片及其制备方法并用其筛选单克隆抗体
US20030054414A1 (en) * 2001-09-17 2003-03-20 George Jackowski Diagnosis and treatment of early pre-type-1 diabetes utilizing glial fibrillary acidic protein

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JP4594588B2 (ja) 2010-12-08
AU2002256168B2 (en) 2007-09-20
CN1602425A (zh) 2005-03-30
EP2302391A1 (en) 2011-03-30
WO2002084249A3 (en) 2003-07-03
EP1386155A2 (en) 2004-02-04
JP2010190898A (ja) 2010-09-02
US20100330110A1 (en) 2010-12-30
CN100405062C (zh) 2008-07-23
EP1386155A4 (en) 2006-05-10
JP2004534213A (ja) 2004-11-11
EP2302387A1 (en) 2011-03-30
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US20030003516A1 (en) 2003-01-02
US7785819B2 (en) 2010-08-31

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