IL158062A0 - Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) - Google Patents
Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)Info
- Publication number
- IL158062A0 IL158062A0 IL15806202A IL15806202A IL158062A0 IL 158062 A0 IL158062 A0 IL 158062A0 IL 15806202 A IL15806202 A IL 15806202A IL 15806202 A IL15806202 A IL 15806202A IL 158062 A0 IL158062 A0 IL 158062A0
- Authority
- IL
- Israel
- Prior art keywords
- crf
- antagonists
- releasing factor
- corticotropin releasing
- fused pyrimidines
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
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- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0465—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0110567A GB0110567D0 (en) | 2001-04-30 | 2001-04-30 | Chemical compounds |
GB0110570A GB0110570D0 (en) | 2001-04-30 | 2001-04-30 | Chemical compounds |
GB0110569A GB0110569D0 (en) | 2001-04-30 | 2001-04-30 | Chemical compounds |
GB0117420A GB0117420D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
GB0117401A GB0117401D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
GB0117399A GB0117399D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
GB0203201A GB0203201D0 (en) | 2002-02-11 | 2002-02-11 | Chemical compounds |
GB0206834A GB0206834D0 (en) | 2002-03-22 | 2002-03-22 | Chemical compounds |
PCT/GB2002/002029 WO2002088095A1 (en) | 2001-04-30 | 2002-04-30 | Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) |
Publications (1)
Publication Number | Publication Date |
---|---|
IL158062A0 true IL158062A0 (en) | 2004-03-28 |
Family
ID=27571152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15806202A IL158062A0 (en) | 2001-04-30 | 2002-04-30 | Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) |
Country Status (19)
Country | Link |
---|---|
US (1) | US7279474B2 (no) |
EP (1) | EP1383747B1 (no) |
JP (1) | JP2004528349A (no) |
KR (1) | KR20040015206A (no) |
CN (1) | CN1649848A (no) |
AR (1) | AR033295A1 (no) |
AT (1) | ATE386727T1 (no) |
AU (1) | AU2002253357B2 (no) |
BR (1) | BR0209267A (no) |
CA (1) | CA2446514A1 (no) |
CZ (1) | CZ20032946A3 (no) |
DE (1) | DE60225127T2 (no) |
ES (1) | ES2301633T3 (no) |
HU (1) | HUP0304054A2 (no) |
IL (1) | IL158062A0 (no) |
MX (1) | MXPA03009938A (no) |
NO (1) | NO20034836L (no) |
PL (1) | PL366934A1 (no) |
WO (1) | WO2002088095A1 (no) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2307750T3 (es) * | 2001-06-12 | 2008-12-01 | Glaxo Group Limited | Antagonistas del factor de liberacion de corticotropina. |
GB0117396D0 (en) * | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
JP2006515334A (ja) * | 2003-01-16 | 2006-05-25 | エスビー ファームコ プエルト リコ インコーポレーテッド | CRF受容体アンタゴニストとしてのヘテロアリール置換ピロロ[2,3−b]ピリジン誘導体 |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
GB0308208D0 (en) * | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
MXPA05011710A (es) * | 2003-05-05 | 2006-01-23 | Hoffmann La Roche | Derivados de pirimidina con actividad de crf. |
WO2005013997A1 (en) | 2003-08-12 | 2005-02-17 | F. Hoffmann-La Roche Ag | Spiro-substituted tetrahydroquinazolines as corticotropin releasing factor (cfr) antagonists |
JP2007501821A (ja) * | 2003-08-12 | 2007-02-01 | エフ.ホフマン−ラ ロシュ アーゲー | Cfrアンタゴニストとしてのテトラヒドロキナゾリン誘導体 |
NZ547990A (en) * | 2003-12-22 | 2010-04-30 | Smithkline Beecham Cork Ltd | CRF receptor antagonists and methods relating thereto |
JP2007517793A (ja) * | 2004-01-06 | 2007-07-05 | 大正製薬株式会社 | 環状アミノ基によって置換されたチエノピリミジン及びチエノピリジン誘導体 |
RU2006135120A (ru) * | 2004-03-05 | 2008-04-10 | Тайсо Фармасьютикал Ко. | Производные пирролопиримидина |
EP1752457B1 (en) | 2004-06-02 | 2014-03-19 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
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2002
- 2002-04-30 EP EP02722478A patent/EP1383747B1/en not_active Expired - Lifetime
- 2002-04-30 PL PL02366934A patent/PL366934A1/xx not_active Application Discontinuation
- 2002-04-30 DE DE60225127T patent/DE60225127T2/de not_active Expired - Fee Related
- 2002-04-30 IL IL15806202A patent/IL158062A0/xx unknown
- 2002-04-30 CA CA002446514A patent/CA2446514A1/en not_active Abandoned
- 2002-04-30 CZ CZ20032946A patent/CZ20032946A3/cs unknown
- 2002-04-30 KR KR10-2003-7014160A patent/KR20040015206A/ko not_active Application Discontinuation
- 2002-04-30 AT AT02722478T patent/ATE386727T1/de not_active IP Right Cessation
- 2002-04-30 AU AU2002253357A patent/AU2002253357B2/en not_active Ceased
- 2002-04-30 HU HU0304054A patent/HUP0304054A2/hu unknown
- 2002-04-30 AR ARP020101597A patent/AR033295A1/es unknown
- 2002-04-30 CN CNA028107462A patent/CN1649848A/zh active Pending
- 2002-04-30 ES ES02722478T patent/ES2301633T3/es not_active Expired - Lifetime
- 2002-04-30 BR BR0209267-0A patent/BR0209267A/pt not_active IP Right Cessation
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- 2002-04-30 WO PCT/GB2002/002029 patent/WO2002088095A1/en active IP Right Grant
- 2002-04-30 JP JP2002585397A patent/JP2004528349A/ja active Pending
- 2002-04-30 MX MXPA03009938A patent/MXPA03009938A/es active IP Right Grant
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AR033295A1 (es) | 2003-12-10 |
NO20034836D0 (no) | 2003-10-29 |
ATE386727T1 (de) | 2008-03-15 |
JP2004528349A (ja) | 2004-09-16 |
CN1649848A (zh) | 2005-08-03 |
NO20034836L (no) | 2003-10-29 |
US7279474B2 (en) | 2007-10-09 |
KR20040015206A (ko) | 2004-02-18 |
DE60225127D1 (en) | 2008-04-03 |
ES2301633T3 (es) | 2008-07-01 |
PL366934A1 (en) | 2005-02-07 |
DE60225127T2 (de) | 2009-02-19 |
US20040176400A1 (en) | 2004-09-09 |
CZ20032946A3 (en) | 2004-05-12 |
WO2002088095A1 (en) | 2002-11-07 |
EP1383747B1 (en) | 2008-02-20 |
CA2446514A1 (en) | 2002-11-07 |
EP1383747A1 (en) | 2004-01-28 |
HUP0304054A2 (hu) | 2004-04-28 |
AU2002253357B2 (en) | 2006-08-24 |
BR0209267A (pt) | 2004-06-15 |
MXPA03009938A (es) | 2005-09-07 |
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