IL155644A0 - Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation - Google Patents

Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation

Info

Publication number
IL155644A0
IL155644A0 IL15564401A IL15564401A IL155644A0 IL 155644 A0 IL155644 A0 IL 155644A0 IL 15564401 A IL15564401 A IL 15564401A IL 15564401 A IL15564401 A IL 15564401A IL 155644 A0 IL155644 A0 IL 155644A0
Authority
IL
Israel
Prior art keywords
processes
preparation
novel crystal
ondansetron hydrochloride
solvate forms
Prior art date
Application number
IL15564401A
Other languages
English (en)
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL155644A0 publication Critical patent/IL155644A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
IL15564401A 2000-10-30 2001-10-30 Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation IL155644A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24428300P 2000-10-30 2000-10-30
US25381900P 2000-11-29 2000-11-29
US26553901P 2001-01-31 2001-01-31
PCT/US2001/048720 WO2002036558A2 (en) 2000-10-30 2001-10-30 Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation

Publications (1)

Publication Number Publication Date
IL155644A0 true IL155644A0 (en) 2003-11-23

Family

ID=27399743

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15564401A IL155644A0 (en) 2000-10-30 2001-10-30 Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation

Country Status (20)

Country Link
US (1) US20020107275A1 (de)
EP (1) EP1339707A2 (de)
JP (1) JP2004525083A (de)
KR (1) KR20030042038A (de)
CN (1) CN1498216A (de)
AU (1) AU2002230935A1 (de)
CA (1) CA2426026A1 (de)
CZ (1) CZ20031397A3 (de)
DE (1) DE01991193T1 (de)
ES (1) ES2204358T1 (de)
HR (1) HRP20030432A2 (de)
HU (1) HUP0401239A2 (de)
IL (1) IL155644A0 (de)
IS (1) IS6797A (de)
MX (1) MXPA03003761A (de)
NO (1) NO20031928L (de)
PL (1) PL366150A1 (de)
SK (1) SK6182003A3 (de)
WO (1) WO2002036558A2 (de)
YU (1) YU32003A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL156835A0 (en) * 2001-01-11 2004-02-08 Teva Pharma An improved process for preparing pure ondansetron hydrochloride dihydrate
US7098345B2 (en) 2002-04-29 2006-08-29 TEVA Gyógyszergyár Zárkörüen Müködö Részvénytársaság Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
EP1828141A4 (de) * 2004-10-26 2009-04-01 Ipca Lab Ltd Eintopfverfahren zur herstellung des antiemetikums 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl)-1h-imidazol-1-yl)methyl]-4h-carbazol-4-on
US20070190145A1 (en) * 2006-01-27 2007-08-16 Eurand, Inc. Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids
KR20140088230A (ko) * 2006-01-27 2014-07-09 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물과 유기산을 포함하는 약물 전달 시스템
EP2099298A4 (de) * 2006-12-07 2010-01-06 Helsinn Healthcare Sa Kristalline und amorphe formen von palonosetron-hydrochlorid
US8133506B2 (en) 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
CN102190594A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
TWI665190B (zh) 2013-11-15 2019-07-11 阿克比治療有限公司 ｛［５－（３－氯苯基）－３－羥基吡啶－２－羰基］胺基｝乙酸之固體型式，其組合物及用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
DE3689974T2 (de) * 1985-03-14 1994-11-03 Beecham Group Plc Arzneimittel zur Behandlung von Emesis.
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5344658A (en) * 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
JPH06508836A (ja) * 1991-06-26 1994-10-06 セプラコア，インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する嘔吐、吐き気および他の障害の治療のための方法および組成物
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
CN1045437C (zh) * 1994-12-29 1999-10-06 中国科学院上海有机化学研究所 恩丹西酮及其生理盐的合成
EP1207160A1 (de) * 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Verfahren zur Herstellung von 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one
US7098345B2 (en) * 2002-04-29 2006-08-29 TEVA Gyógyszergyár Zárkörüen Müködö Részvénytársaság Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one
DE20320528U1 (de) * 2002-04-30 2004-09-16 Teva Pharmaceuticals Usa, Inc. Neue Kristallformen von Ondansetron und Arzneimittel, welche die neuen Formen enthalten

Also Published As

Publication number Publication date
HUP0401239A2 (hu) 2004-12-28
HRP20030432A2 (en) 2004-06-30
CN1498216A (zh) 2004-05-19
AU2002230935A1 (en) 2002-05-15
WO2002036558A3 (en) 2003-02-06
US20020107275A1 (en) 2002-08-08
NO20031928D0 (no) 2003-04-29
WO2002036558A2 (en) 2002-05-10
PL366150A1 (en) 2005-01-24
IS6797A (is) 2003-04-29
YU32003A (sh) 2006-05-25
ES2204358T1 (es) 2004-05-01
NO20031928L (no) 2003-06-27
DE01991193T1 (de) 2004-07-08
JP2004525083A (ja) 2004-08-19
CZ20031397A3 (cs) 2003-11-12
EP1339707A2 (de) 2003-09-03
MXPA03003761A (es) 2003-07-28
CA2426026A1 (en) 2002-05-10
SK6182003A3 (en) 2004-03-02
KR20030042038A (ko) 2003-05-27

Similar Documents

Publication Publication Date Title
HK1086263A1 (en) Crystal form of lercanidipine hydrochloride for use as an antihypertensive agent
KR100908796B9 (ko) 아세트산아닐리드 유도체의 α형 또는 β형 결정
EP1383743A4 (de) Duale inhibitoren von pde 7 und pde 4
EP1193333A4 (de) Verfahren zur herstellung von silizium-einkristallen und silizium-einkristall
IL160721A0 (en) Crystalline forms of valacyclovir hydrochloride
IL155644A0 (en) Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation
PL373845A1 (en) Crystal forms of olanzapine and processes for their preparation
NO20042810L (no) Venflaxine-hydroklorid-monohydrat og fremgangsmater for fremstilling derav
AU2002337843A8 (en) Processes for the preparation of substituted isoxazoles and 2-isoxazolines
IL153916A0 (en) Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride obtained from said solvates
PL355426A1 (en) Process for the preparation of secondary and tertiary amines
HUP0001558A3 (en) Process for the preparation of pirlindole hydrochloride
GB0115103D0 (en) Apparatus for and methods of preparing sperm
EP1694242A4 (de) Pharmazeutische formulierungen von campothecinen und herstellungsverfahren
AU2002213477A1 (en) Process for preparation of n-substituted 2-sulfanylimidazoles
HUP0302144A3 (en) Process of preparation of aliphatic amines
IL157243A0 (en) Preparation of n-methylparoxetine and related intermediate compounds
IL149807A0 (en) Process for the preparation of secondary and tertiary amines
AU2002348942A8 (en) Process for the preparation of tofisopam and new intermediates
HUP0203901A3 (en) Process for the preparation of secondary and tertiary amines
TWI319389B (en) Process for preparing succinonitrile and use of succinonitirile
PL332676A1 (en) Method of obtaining benzidamine hydrochloride
PL348216A1 (en) Method of obtaining n-(triarylmethyl)-1-amino-2-hydroxyalkanes
AU2002248268A8 (en) Crystal modification of olanzapine
PL339715A1 (en) Method of obtaining n-(triarylmethyl)-3-alkylthiopropanimines