IL155154A0 - Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating - Google Patents

Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating

Info

Publication number
IL155154A0
IL155154A0 IL15515401A IL15515401A IL155154A0 IL 155154 A0 IL155154 A0 IL 155154A0 IL 15515401 A IL15515401 A IL 15515401A IL 15515401 A IL15515401 A IL 15515401A IL 155154 A0 IL155154 A0 IL 155154A0
Authority
IL
Israel
Prior art keywords
mutagenizing
substantial portion
whole cell
optionally repeating
cell engineering
Prior art date
Application number
IL15515401A
Other languages
English (en)
Original Assignee
Diversa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/677,584 external-priority patent/US7033781B1/en
Priority claimed from PCT/US2001/019367 external-priority patent/WO2001096551A2/fr
Application filed by Diversa Corp filed Critical Diversa Corp
Priority claimed from PCT/US2001/031004 external-priority patent/WO2002029032A2/fr
Publication of IL155154A0 publication Critical patent/IL155154A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Ecology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
IL15515401A 2000-09-30 2001-10-01 Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating IL155154A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/677,584 US7033781B1 (en) 1999-09-29 2000-09-30 Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating
US27970201P 2001-03-28 2001-03-28
PCT/US2001/019367 WO2001096551A2 (fr) 2000-06-14 2001-06-14 Ingenierie cellulaire complete par mutagenese d'une partie substantielle d'un genome de depart, par combinaison de mutations et eventuellement repetition
PCT/US2001/031004 WO2002029032A2 (fr) 2000-09-30 2001-10-01 Manipulation de cellule entiere par mutagenese d'une partie substantielle d'un genome de depart, par combinaison de mutations et eventuellement par repetition

Publications (1)

Publication Number Publication Date
IL155154A0 true IL155154A0 (en) 2003-10-31

Family

ID=32599643

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15515401A IL155154A0 (en) 2000-09-30 2001-10-01 Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating

Country Status (7)

Country Link
US (1) US20050124010A1 (fr)
EP (1) EP1415160A2 (fr)
JP (1) JP2004536553A (fr)
AU (1) AU2002211402A1 (fr)
CA (1) CA2424178A1 (fr)
DE (1) DE01979431T1 (fr)
IL (1) IL155154A0 (fr)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100391884B1 (en) * 2002-07-04 2003-09-06 Amicogen Co Ltd Random codon based mutagenesis using transposon
MXPA05008857A (es) * 2003-02-18 2006-03-09 Metabolic Explorer Sa Procedimiento de preparacion de microorganismos evolucionados que permite la creacion o la modificacion de vias metabolicas.
JP2007534320A (ja) * 2004-02-27 2007-11-29 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ ポリヌクレオチド合成法
US7685737B2 (en) 2004-07-19 2010-03-30 Earthrenew, Inc. Process and system for drying and heat treating materials
US7024800B2 (en) 2004-07-19 2006-04-11 Earthrenew, Inc. Process and system for drying and heat treating materials
US20070042397A1 (en) * 2005-03-03 2007-02-22 International Business Machines Corporation Techniques for linking non-coding and gene-coding deoxyribonucleic acid sequences and applications thereof
DE102005018273B4 (de) * 2005-04-20 2007-11-15 Bruker Daltonik Gmbh Rückgesteuerte Tandem-Massenspektrometrie
WO2007005053A1 (fr) * 2005-06-30 2007-01-11 Codon Devices, Inc. Procédés d'assemblage hiérarchique pour l'ingénierie des génomes
US20070026012A1 (en) * 2005-08-01 2007-02-01 Cornell Research Foundation, Inc. Compositions and methods for monitoring and altering protein folding and solubility
WO2007024877A2 (fr) * 2005-08-22 2007-03-01 Cornell Research Foundation, Inc. Compositions et methodes permettant d'analyser des interactions de proteines
US7707206B2 (en) * 2005-09-21 2010-04-27 Praxeon, Inc. Document processing
US8682619B2 (en) * 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8734823B2 (en) * 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US20110172826A1 (en) * 2005-12-14 2011-07-14 Amodei Dario G Device including altered microorganisms, and methods and systems of use
US20110182859A1 (en) * 2010-01-22 2011-07-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with microorganisms
US7610692B2 (en) 2006-01-18 2009-11-03 Earthrenew, Inc. Systems for prevention of HAP emissions and for efficient drying/dehydration processes
US20080126263A1 (en) * 2006-03-07 2008-05-29 George Sugihara Transferable by-catch quotas
DK2024504T4 (da) 2006-05-26 2023-02-27 Amyris Inc Fremstilling af isoprenoider
JP4630940B2 (ja) * 2006-05-26 2011-02-09 アムイリス ビオテクフノロジエス，インコーポレイテッド 燃料成分、燃料組成物、並びにこれらの製造方法、及び使用方法。
AP2724A (en) 2006-07-21 2013-08-31 Xyleco Inc Conversion systems for biomass
JP5445131B2 (ja) * 2006-12-22 2014-03-19 富士レビオ株式会社 バイオセンサおよびバイオセンサチップ、ならびに標的分子を感知するためのバイオセンサチップの製造方法
US8722584B2 (en) * 2007-01-12 2014-05-13 Cornell University Genetic selection for protein folding and solubility in the bacterial periplasm
US20090068741A1 (en) * 2007-01-17 2009-03-12 Invitrogen Corporation Methods and Compositions for Improving the Health of Cells in Culture
EP3431099B1 (fr) 2007-03-30 2024-01-03 The Research Foundation for The State University of New York Virus attenues utiles pour des vaccins
US8005643B2 (en) * 2007-06-26 2011-08-23 Endeca Technologies, Inc. System and method for measuring the quality of document sets
US8935249B2 (en) 2007-06-26 2015-01-13 Oracle Otc Subsidiary Llc Visualization of concepts within a collection of information
US20090011516A1 (en) * 2007-07-03 2009-01-08 Pioneer Hi-Bred International, Inc. Methods and Assays for the Detection of Nitrogen Uptake by a Plant and Uses Thereof
US20090024329A1 (en) * 2007-07-19 2009-01-22 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems relating to epigenetic information
US20090022666A1 (en) * 2007-07-19 2009-01-22 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems relating to mitochondrial DNA information
US20090024330A1 (en) * 2007-07-19 2009-01-22 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems relating to epigenetic phenotypes
US20090024333A1 (en) * 2007-07-19 2009-01-22 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems relating to mitochondrial DNA phenotypes
JP2010536345A (ja) * 2007-08-14 2010-12-02 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 新規な方法および細胞系
BRPI0818888A2 (pt) * 2007-10-26 2014-11-04 Arbor Fuel Inc Métodos para a produção de n-butanol.
EP2227553A4 (fr) * 2007-11-30 2011-01-19 Scarab Genomics Llc Système d'expression de lac
ES2937659T3 (es) * 2008-02-04 2023-03-30 Hazera Seeds Ltd Plantas de pimiento resistentes a enfermedades
US8048654B2 (en) * 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
EP2706111A1 (fr) 2008-03-03 2014-03-12 Joule Unlimited Technologies, Inc. Micro-organismes fixateurs de CO2 obtenus par génie génétique produisant des produits carbonés d'intérêt
WO2009124012A1 (fr) * 2008-03-31 2009-10-08 Dow Global Technologies Inc. Technique pour cloner rapidement une ou plusieurs chaînes polypeptidiques dans un système d'expression
EP2297326A4 (fr) 2008-06-06 2011-11-16 Aurora Biofuels Inc Vecteurs à base de vcp pour la transformation de cellules d'algues
US20100022393A1 (en) * 2008-07-24 2010-01-28 Bertrand Vick Glyphosate applications in aquaculture
EP2998402A1 (fr) 2008-10-17 2016-03-23 Joule Unlimited Technologies, Inc. Production d'éthanol par des microorganismes
KR101660852B1 (ko) 2008-12-23 2016-09-28 조마 (유에스) 엘엘씨 유연성 제조 시스템
US8314228B2 (en) 2009-02-13 2012-11-20 Aurora Algae, Inc. Bidirectional promoters in Nannochloropsis
US8865468B2 (en) 2009-10-19 2014-10-21 Aurora Algae, Inc. Homologous recombination in an algal nuclear genome
US8809046B2 (en) 2011-04-28 2014-08-19 Aurora Algae, Inc. Algal elongases
US20100318371A1 (en) * 2009-06-11 2010-12-16 Halliburton Energy Services, Inc. Comprehensive hazard evaluation system and method for chemicals and products
US8709765B2 (en) * 2009-07-20 2014-04-29 Aurora Algae, Inc. Manipulation of an alternative respiratory pathway in photo-autotrophs
US20110020867A1 (en) * 2009-07-20 2011-01-27 Joule Unlimited, Inc. Constructs And Methods For Efficient Transformation Of Micro-Organisms For Production Of Carbon-Based Products Of Interest
BR112012003549B1 (pt) * 2009-08-16 2020-08-04 G-Con Manufacturing Inc Estrutura unitária, unidade de biossegurança e método de fazer uma unidade prévalidável unitária
US9795957B2 (en) 2009-08-16 2017-10-24 G-Con Manufacturing, Inc. Modular, self-contained, mobile clean room
US9203747B1 (en) 2009-12-07 2015-12-01 Amazon Technologies, Inc. Providing virtual networking device functionality for managed computer networks
US8995301B1 (en) 2009-12-07 2015-03-31 Amazon Technologies, Inc. Using virtual networking devices to manage routing cost information
US9036504B1 (en) 2009-12-07 2015-05-19 Amazon Technologies, Inc. Using virtual networking devices and routing information to associate network addresses with computing nodes
US7937438B1 (en) * 2009-12-07 2011-05-03 Amazon Technologies, Inc. Using virtual networking devices to manage external connections
US8383417B2 (en) * 2009-12-22 2013-02-26 Thermo Finnigan, Llc Assay for monitoring parathyroid hormone (PTH) variants by tandem mass spectrometry
US7991859B1 (en) 2009-12-28 2011-08-02 Amazon Technologies, Inc. Using virtual networking devices to connect managed computer networks
US7953865B1 (en) 2009-12-28 2011-05-31 Amazon Technologies, Inc. Using virtual networking devices to manage routing communications between connected computer networks
US8224971B1 (en) 2009-12-28 2012-07-17 Amazon Technologies, Inc. Using virtual networking devices and routing information to initiate external actions
US20130071919A1 (en) * 2010-03-10 2013-03-21 Kyoto University Method of selecting induced pluripotent stem cell
US20130109098A1 (en) * 2010-07-06 2013-05-02 Phycal, Inc Biosecure genetically modified algae
US8722359B2 (en) 2011-01-21 2014-05-13 Aurora Algae, Inc. Genes for enhanced lipid metabolism for accumulation of lipids
WO2012118933A1 (fr) * 2011-03-01 2012-09-07 Rutgers, The State University Of New Jersey Microbes génétiquement modifiés et leurs utilisations
MX2013012565A (es) 2011-04-28 2013-11-21 Aurora Algae Inc Desaturasas de algas.
WO2013166065A1 (fr) 2012-04-30 2013-11-07 Aurora Algae, Inc. Promoteur d'acp
US9410162B1 (en) 2012-07-24 2016-08-09 Arrowhead Center, Inc. Transgenic legumes
EP3041498B1 (fr) * 2013-09-05 2022-02-16 Massachusetts Institute of Technology Réglage de populations microbiennes à l'aide de nucléases programmables
US20150091546A1 (en) * 2013-09-27 2015-04-02 Tel Solar Ag Power measurement analysis of photovoltaic modules
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
JP2017514488A (ja) * 2014-05-02 2017-06-08 タフツ ユニバーシティー 自然コンピテント細胞の形質転換のための方法および装置
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CA3090392C (fr) * 2015-12-07 2021-06-01 Zymergen Inc. Amelioration de souches microbiennes par une plateforme d'ingenierie genomique htp
US9988624B2 (en) * 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
CA3007635A1 (fr) 2015-12-07 2017-06-15 Zymergen Inc. Promoteurs de corynebacterium glutamicum
KR102345898B1 (ko) 2016-06-30 2022-01-03 지머젠 인코포레이티드 글루코오스 투과 효소 라이브러리를 생성하는 방법 및 이의 용도
US10544390B2 (en) 2016-06-30 2020-01-28 Zymergen Inc. Methods for generating a bacterial hemoglobin library and uses thereof
EA201990599A1 (ru) 2016-09-27 2019-10-31 Способ и система для получения и секвенирования библиотеки на основе crispr
US10255990B2 (en) 2016-11-11 2019-04-09 uBiome, Inc. Method and system for fragment assembly and sequence identification
CN108728477B (zh) * 2017-04-24 2022-02-22 华东理工大学 一种高效的转座突变系统及构建方法
CN108363905B (zh) * 2018-02-07 2019-03-08 南京晓庄学院 一种用于植物外源基因改造的CodonPlant系统及其改造方法
CN110521617B (zh) * 2018-05-25 2022-06-17 中国科学院深圳先进技术研究院 一种动物行为监测系统
CN108753620A (zh) * 2018-05-30 2018-11-06 昆明理工大学 一种提高雨生红球藻生物量和虾青素含量的方法
CN108921352B (zh) * 2018-07-06 2021-10-22 东北大学 一种具有区间不确定性的湿法冶金浸出过程优化方法
CN113272646B (zh) * 2018-07-16 2023-10-24 加利福尼亚大学董事会 关联复杂数据
CN111198272B (zh) * 2018-11-20 2023-09-08 香港理工大学深圳研究院 体外检测蛋白间相互作用的方法和检测试剂盒及其应用
CN109540842B (zh) * 2019-01-15 2023-09-19 南京大学 基于led光源的双荧光信号与水质监测探头及使用方法
CN110543113B (zh) * 2019-07-17 2022-12-02 杭州迦智科技有限公司 机器人硬件组装及管理方法、设备、介质、系统、前端组装客户端及机器人本体运行系统
WO2021030568A1 (fr) 2019-08-15 2021-02-18 G-Con Manufacturing, Inc. Toit à panneaux amovibles pour salle blanche modulaire autonome et mobile
CN112442505B (zh) * 2019-09-03 2023-06-23 河北北方学院 一种马铃薯StRab5b基因的克隆、载体构建和瞬时表达的研究方法
CN112766296B (zh) * 2019-11-06 2023-04-07 济南信通达电气科技有限公司 输电线路安全隐患目标检测模型训练方法及装置
US11708605B2 (en) 2019-11-06 2023-07-25 Adaptive Biotechnologies Corporation Synthetic strands for nucleic acid sequencing and related methods and systems
CN111073905B (zh) * 2019-12-11 2022-08-23 南京农业大学 大豆丝裂原活化蛋白激酶GmMMK1编码基因的应用
CN111154798B (zh) * 2020-02-18 2021-07-20 杭州师范大学 马铃薯x病毒在诱导番茄种子胎萌中的应用及应用方法
CN111471668B (zh) * 2020-02-28 2022-05-24 浙江工业大学 一种腈水解酶突变体及其在制备1-氰基环己基乙酸中的应用
WO2021207265A1 (fr) * 2020-04-08 2021-10-14 Zymergen Inc. Générateur de bibliothèque de souches automatisée à haut débit
CA3175222A1 (fr) * 2020-04-14 2021-10-21 Marcel Tijsterman Procedes d'induction d'evenements de duplication en tandem endogenes
CN111690777B (zh) * 2020-07-15 2023-06-02 西南大学 柑橘叶斑驳病毒rt-rpa检测的特异引物、试剂盒和方法
CN111849995B (zh) * 2020-08-04 2021-12-10 福州金域医学检验所有限公司 不耐热溶血素tlh的核酸适配体tlh01及其应用
WO2022039847A1 (fr) * 2020-08-21 2022-02-24 Inari Agriculture Technology, Inc. Évaluation d'effet de variant à base d'apprentissage automatique et ses utilisations
US11492795B2 (en) 2020-08-31 2022-11-08 G-Con Manufacturing, Inc. Ballroom-style cleanroom assembled from modular buildings
CN113151354B (zh) * 2021-03-22 2022-03-08 中国农业科学院兰州兽医研究所 一种用于条件性敲除目的基因的载体及条件性敲除目的基因的方法
CN113155800B (zh) * 2021-05-04 2023-11-07 浙江师范大学 激光共聚焦显影观测定量葡萄籽物料中油脂的方法
CN113736895B (zh) * 2021-08-09 2024-05-10 江苏大学 一种超声诱变的鼠伤寒沙门氏菌hisD基因InDel分子标记及应用
CN115802323B (zh) * 2022-11-28 2023-10-10 南京邮电大学 一种基于边缘计算-d2d的区块链资源共享方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
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FR2716682B1 (fr) * 1994-01-28 1996-04-26 Centre Nat Rech Scient Procédé de préparation de virus adéno-associés (AAV) recombinants et utilisations.
AU744725B2 (en) * 1997-03-03 2002-02-28 Cold Genesys, Inc. Adenovirus vectors containing heterologous transcription regulatory elements and methods of using same
ATE319835T1 (de) * 1998-08-18 2006-03-15 Metabolix Inc Transgene polyhydroxyalkanoat produzierende mikroben

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CA2424178A1 (fr) 2002-04-11
AU2002211402A1 (en) 2002-04-15
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US20050124010A1 (en) 2005-06-09
EP1415160A2 (fr) 2004-05-06
JP2004536553A (ja) 2004-12-09

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