IL151887A0 - 2-hydroxy-mutilin carbamate derivatives for antibacterial use - Google Patents
2-hydroxy-mutilin carbamate derivatives for antibacterial useInfo
- Publication number
- IL151887A0 IL151887A0 IL15188701A IL15188701A IL151887A0 IL 151887 A0 IL151887 A0 IL 151887A0 IL 15188701 A IL15188701 A IL 15188701A IL 15188701 A IL15188701 A IL 15188701A IL 151887 A0 IL151887 A0 IL 151887A0
- Authority
- IL
- Israel
- Prior art keywords
- hydroxy
- carbamate derivatives
- antibacterial use
- mutilin carbamate
- mutilin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0008260.2A GB0008260D0 (en) | 2000-04-04 | 2000-04-04 | Novel compounds |
| GB0027182A GB0027182D0 (en) | 2000-11-04 | 2000-11-04 | Novel comounds |
| PCT/EP2001/003594 WO2001074788A1 (en) | 2000-04-04 | 2001-03-29 | 2-hydroxy-mutilin carbamate derivatives for antibacterial use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL151887A0 true IL151887A0 (en) | 2003-04-10 |
Family
ID=26244040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15188701A IL151887A0 (en) | 2000-04-04 | 2001-03-29 | 2-hydroxy-mutilin carbamate derivatives for antibacterial use |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6972297B2 (no) |
| EP (1) | EP1268443B1 (no) |
| JP (1) | JP2003529593A (no) |
| KR (1) | KR100758441B1 (no) |
| CN (1) | CN1210267C (no) |
| AR (1) | AR030203A1 (no) |
| AT (1) | ATE437860T1 (no) |
| AU (2) | AU6382701A (no) |
| BR (1) | BR0109809A (no) |
| CA (1) | CA2405132A1 (no) |
| CO (1) | CO5280223A1 (no) |
| CZ (1) | CZ20023290A3 (no) |
| DE (1) | DE60139382D1 (no) |
| ES (1) | ES2328109T3 (no) |
| HU (1) | HUP0300370A3 (no) |
| IL (1) | IL151887A0 (no) |
| MX (1) | MXPA02009816A (no) |
| NO (1) | NO324229B1 (no) |
| NZ (1) | NZ521536A (no) |
| PL (1) | PL358666A1 (no) |
| WO (1) | WO2001074788A1 (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0024811D0 (en) | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
| GB0209262D0 (en) * | 2002-04-23 | 2002-06-05 | Biochemie Gmbh | Organic compounds |
| MXPA05000984A (es) * | 2002-07-24 | 2005-09-12 | Sandoz Ag | Derivados de pleuromutilina como antimicrobianos. |
| GB0218578D0 (en) | 2002-08-09 | 2002-09-18 | Glaxo Group Ltd | Novel method |
| GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
| FR2856685B1 (fr) * | 2003-06-25 | 2005-09-23 | Merck Sante Sas | Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| US20090291987A1 (en) * | 2004-12-13 | 2009-11-26 | Glaxo Group Limited | Novel polymorph of (5-amino-6-methoxy-3-pyridincarbonyl) carbamic acid 2-(s)-hydroxymutilin 14-ester |
| KR20070094786A (ko) * | 2004-12-27 | 2007-09-21 | 교린 세이야꾸 가부시키 가이샤 | 12번 위치가 치환된 무틸린 유도체 |
| US20080139626A1 (en) * | 2005-03-10 | 2008-06-12 | Rittenhouse Stephen F | Novel Method |
| TW200738701A (en) | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| KR100695541B1 (ko) * | 2005-10-31 | 2007-03-16 | 한국단자공업 주식회사 | 연결터미널 |
| WO2007079173A2 (en) * | 2005-12-30 | 2007-07-12 | Emergent Biosolutions Inc. | Novel 2-heteroaryloxy-phenol derivatives as antibacterial agents |
| WO2008143343A1 (ja) | 2007-05-24 | 2008-11-27 | Kyorin Pharmaceutical Co., Ltd. | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| EP2014640A1 (en) * | 2007-07-13 | 2009-01-14 | Nabriva Therapeutics AG | Pleuromutilin derivatives |
| JP2010100582A (ja) * | 2008-10-24 | 2010-05-06 | Kyorin Pharmaceut Co Ltd | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| EP2253617A1 (de) | 2009-05-20 | 2010-11-24 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| WO2016202788A1 (en) * | 2015-06-17 | 2016-12-22 | Nabriva Therapeutics Ag | Injectable pharmaceutical formulations of lefamulin |
| EP3930808A4 (en) * | 2019-02-27 | 2022-12-14 | Oticara, Inc. | METHOD OF TREATING NASAL, NASOSINUS AND RHINOPHARYNGEAL INFECTION AND/OR INFLAMMATION |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ212498A3 (cs) | 1996-01-03 | 1998-12-16 | Smithkline Beecham P. L. C. | Karbamoyloxyderiváty mutilinu, způsob výroby a farmaceutický prosředek |
| HUP0001741A3 (en) | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| UY25225A1 (es) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
| FR2771008B1 (fr) | 1997-11-17 | 2000-04-28 | Hoechst Marion Roussel Inc | Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose |
| GB9817029D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Plc | Novel compounds |
-
2001
- 2001-03-29 MX MXPA02009816A patent/MXPA02009816A/es active IP Right Grant
- 2001-03-29 ES ES01938069T patent/ES2328109T3/es not_active Expired - Lifetime
- 2001-03-29 AU AU6382701A patent/AU6382701A/xx not_active Withdrawn
- 2001-03-29 NZ NZ521536A patent/NZ521536A/en unknown
- 2001-03-29 DE DE60139382T patent/DE60139382D1/de not_active Expired - Lifetime
- 2001-03-29 US US10/240,908 patent/US6972297B2/en not_active Expired - Fee Related
- 2001-03-29 EP EP01938069A patent/EP1268443B1/en not_active Expired - Lifetime
- 2001-03-29 CA CA002405132A patent/CA2405132A1/en not_active Abandoned
- 2001-03-29 BR BR0109809-8A patent/BR0109809A/pt not_active Application Discontinuation
- 2001-03-29 KR KR1020027013202A patent/KR100758441B1/ko not_active IP Right Cessation
- 2001-03-29 AU AU2001263827A patent/AU2001263827B2/en not_active Ceased
- 2001-03-29 HU HU0300370A patent/HUP0300370A3/hu unknown
- 2001-03-29 AT AT01938069T patent/ATE437860T1/de not_active IP Right Cessation
- 2001-03-29 CZ CZ20023290A patent/CZ20023290A3/cs unknown
- 2001-03-29 CN CNB018091989A patent/CN1210267C/zh not_active Expired - Fee Related
- 2001-03-29 IL IL15188701A patent/IL151887A0/xx unknown
- 2001-03-29 JP JP2001572483A patent/JP2003529593A/ja active Pending
- 2001-03-29 PL PL01358666A patent/PL358666A1/xx not_active Application Discontinuation
- 2001-03-29 WO PCT/EP2001/003594 patent/WO2001074788A1/en active IP Right Grant
- 2001-03-30 AR ARP010101559A patent/AR030203A1/es not_active Application Discontinuation
- 2001-03-30 CO CO01025487A patent/CO5280223A1/es not_active Application Discontinuation
-
2002
- 2002-10-02 NO NO20024745A patent/NO324229B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ521536A (en) | 2004-05-28 |
| AU6382701A (en) | 2001-10-15 |
| NO20024745D0 (no) | 2002-10-02 |
| PL358666A1 (en) | 2004-08-09 |
| CA2405132A1 (en) | 2001-10-11 |
| WO2001074788A8 (en) | 2001-12-20 |
| WO2001074788A1 (en) | 2001-10-11 |
| KR20030011815A (ko) | 2003-02-11 |
| JP2003529593A (ja) | 2003-10-07 |
| MXPA02009816A (es) | 2003-03-27 |
| EP1268443A1 (en) | 2003-01-02 |
| US20030114674A1 (en) | 2003-06-19 |
| ES2328109T3 (es) | 2009-11-10 |
| KR100758441B1 (ko) | 2007-09-14 |
| ATE437860T1 (de) | 2009-08-15 |
| AR030203A1 (es) | 2003-08-13 |
| BR0109809A (pt) | 2003-01-21 |
| HUP0300370A3 (en) | 2005-07-28 |
| DE60139382D1 (de) | 2009-09-10 |
| CN1210267C (zh) | 2005-07-13 |
| HUP0300370A2 (hu) | 2003-06-28 |
| US6972297B2 (en) | 2005-12-06 |
| CZ20023290A3 (cs) | 2003-03-12 |
| CN1427827A (zh) | 2003-07-02 |
| CO5280223A1 (es) | 2003-05-30 |
| EP1268443B1 (en) | 2009-07-29 |
| NO20024745L (no) | 2002-11-19 |
| AU2001263827B2 (en) | 2004-06-17 |
| NO324229B1 (no) | 2007-09-10 |
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