IL149142A0 - Ligand activated transcriptional regulator proteins - Google Patents
Ligand activated transcriptional regulator proteinsInfo
- Publication number
- IL149142A0 IL149142A0 IL14914200A IL14914200A IL149142A0 IL 149142 A0 IL149142 A0 IL 149142A0 IL 14914200 A IL14914200 A IL 14914200A IL 14914200 A IL14914200 A IL 14914200A IL 149142 A0 IL149142 A0 IL 149142A0
- Authority
- IL
- Israel
- Prior art keywords
- transcriptional regulator
- regulator proteins
- ligand activated
- activated transcriptional
- ligand
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- High Energy & Nuclear Physics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43304299A | 1999-10-25 | 1999-10-25 | |
| US09/586,625 US7329728B1 (en) | 1999-10-25 | 2000-06-02 | Ligand activated transcriptional regulator proteins |
| PCT/EP2000/010430 WO2001030843A1 (en) | 1999-10-25 | 2000-10-23 | Ligand activated transcriptional regulator proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL149142A0 true IL149142A0 (en) | 2002-11-10 |
Family
ID=27029724
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14914200A IL149142A0 (en) | 1999-10-25 | 2000-10-23 | Ligand activated transcriptional regulator proteins |
| IL149142A IL149142A (en) | 1999-10-25 | 2002-04-15 | Ligand activated transcriptional regulator fusion protein, nucleic acid molecule encoding the same and use thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL149142A IL149142A (en) | 1999-10-25 | 2002-04-15 | Ligand activated transcriptional regulator fusion protein, nucleic acid molecule encoding the same and use thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7329728B1 (https=) |
| EP (1) | EP1226168A1 (https=) |
| JP (2) | JP2003512827A (https=) |
| AU (1) | AU775988B2 (https=) |
| CA (1) | CA2388535A1 (https=) |
| IL (2) | IL149142A0 (https=) |
| NZ (1) | NZ518218A (https=) |
| WO (1) | WO2001030843A1 (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001000815A1 (en) * | 1999-05-28 | 2001-01-04 | Sangamo Biosciences, Inc. | Molecular switches |
| US7329728B1 (en) | 1999-10-25 | 2008-02-12 | The Scripps Research Institute | Ligand activated transcriptional regulator proteins |
| ATE355368T1 (de) * | 2000-01-24 | 2006-03-15 | Gendaq Ltd | Nucleinsäure bindende polypeptide gekennzeichnet durch flexible linker verbundene nucleinsäuredomäne |
| US7011972B2 (en) | 2000-07-18 | 2006-03-14 | The Scripps Research Institute | Fusion polypeptide comprising two ligand binding domains |
| IL153833A0 (en) * | 2000-07-18 | 2003-07-31 | Novartis Ag | Regulation of gene expression using single-chain, monomeric, ligand dependent polypeptide switches |
| US6919204B2 (en) | 2000-09-29 | 2005-07-19 | Sangamo Biosciences, Inc. | Modulation of gene expression using localization domains |
| AU2002213431A1 (en) * | 2000-09-29 | 2002-04-08 | Sangamo Biosciences, Inc. | Modulation of gene expression using localization domains |
| WO2002057293A2 (en) | 2001-01-22 | 2002-07-25 | Sangamo Biosciences, Inc. | Modified zinc finger binding proteins |
| IL157335A0 (en) | 2001-03-13 | 2004-02-19 | Novartis Ag | Lentiviral packaging constructs |
| EP1397382B1 (en) | 2001-05-31 | 2008-08-06 | Novartis AG | Novel estrogen receptor ligand binding domain variants and novel ligands and pharmaceutical compositions |
| ES2439874T3 (es) | 2002-05-29 | 2014-01-27 | Regeneron Pharmaceuticals, Inc. | Sistema de expresión en eucariotas inducible |
| US8673589B2 (en) | 2002-05-29 | 2014-03-18 | Regeneron Pharmaceuticals, Inc. | Inducible eukaryotic expression system |
| EP1627046A4 (en) * | 2003-05-06 | 2008-02-13 | Scripps Research Inst | BINDING MOLECULES WITH DOMAIN EXCHANGE, USE METHOD AND METHOD OF MANUFACTURE |
| EP1680447A2 (en) * | 2003-10-24 | 2006-07-19 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Orthogonal gene switches |
| US7829528B2 (en) * | 2004-09-14 | 2010-11-09 | The Rockefeller University | Compositions and methods for treating STAT-6 associated diseases or conditions |
| US20110294135A1 (en) * | 2007-08-02 | 2011-12-01 | BioDesic, LLC | Compositions and methods for analyte detection and quantitation |
| EP2441774B1 (en) | 2010-10-15 | 2018-12-12 | Fundació Centre de Regulació Genòmica | Peptides having zinc finger domains and uses thereof |
| US20130137173A1 (en) * | 2011-11-30 | 2013-05-30 | Feng Zhang | Nucleotide-specific recognition sequences for designer tal effectors |
| US10801017B2 (en) | 2011-11-30 | 2020-10-13 | The Broad Institute, Inc. | Nucleotide-specific recognition sequences for designer TAL effectors |
| US8450107B1 (en) | 2011-11-30 | 2013-05-28 | The Broad Institute Inc. | Nucleotide-specific recognition sequences for designer TAL effectors |
| RU2662672C2 (ru) * | 2012-02-02 | 2018-07-26 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пестицидные композиции и относящиеся к ним способы |
| JP6188728B2 (ja) | 2012-02-07 | 2017-08-30 | グローバル・バイオ・セラピューティクス・インコーポレイテッドGlobal Bio Therapeutics,Inc. | 核酸送達の区画化方法ならびにその組成物および使用 |
| WO2014197748A2 (en) * | 2013-06-05 | 2014-12-11 | Duke University | Rna-guided gene editing and gene regulation |
| HK1225258B (en) | 2013-08-08 | 2017-09-08 | Global Bio Therapeutics, Inc. | Clamping device for minimally invasive surgery |
| WO2017134137A1 (en) * | 2016-02-05 | 2017-08-10 | Polygene Ag | Glucocorticoid-based gene regulation system |
| WO2017181152A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| MX2018012472A (es) | 2016-04-15 | 2019-08-12 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras variantes de ligando icos y sus usos. |
| WO2018022945A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd112 variant immunomodulatory proteins and uses thereof |
| US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
| WO2018022946A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd155 variant immunomodulatory proteins and uses thereof |
| WO2018075978A1 (en) | 2016-10-20 | 2018-04-26 | Alpine Immune Sciences, Inc. | Secretable variant immunomodulatory proteins and engineered cell therapy |
| EP3596116B1 (en) | 2017-03-16 | 2023-09-06 | Alpine Immune Sciences, Inc. | Pd-l1 variant immunomodulatory proteins and uses thereof |
| KR20190141146A (ko) | 2017-03-16 | 2019-12-23 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Pd-l2 변이체 면역조절 단백질 및 그의 용도 |
| SG11201907769XA (en) | 2017-03-16 | 2019-09-27 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
| JP7749319B2 (ja) | 2017-10-10 | 2025-10-06 | アルパイン イミューン サイエンシズ インコーポレイテッド | Ctla-4変異型免疫調節タンパク質およびそれらの使用 |
| BR112020007542A2 (pt) | 2017-10-18 | 2020-12-01 | Alpine Immune Sciences, Inc. | proteínas imunomoduladoras ligantes de icos variantes e composições e métodos relacionados |
| EP3717505A4 (en) * | 2017-12-01 | 2021-12-01 | Encoded Therapeutics, Inc. | GENENICALLY MODIFIED DNA-BINDING PROTEINS |
| AU2019205273B2 (en) | 2018-01-03 | 2024-04-04 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
| EP3853247A2 (en) | 2018-09-19 | 2021-07-28 | Alpine Immune Sciences, Inc. | Methods and uses of variant cd80 fusion proteins and related constructs |
| SG11202104337PA (en) | 2018-11-26 | 2021-05-28 | Massachusetts Inst Technology | Compositions and methods for immune tolerance |
| CA3120868A1 (en) | 2018-11-30 | 2020-06-04 | Alpine Immune Sciences, Inc. | Cd86 variant immunomodulatory proteins and uses thereof |
| MX2021012607A (es) | 2019-04-17 | 2022-03-11 | Alpine Immune Sciences Inc | Metodos y usos de proteinas de fusion de ligando icos (icosl) variante. |
| KR20220015443A (ko) * | 2019-05-28 | 2022-02-08 | 옥탄트, 인크. | 전사 릴레이 시스템 |
| PL3976798T3 (pl) | 2019-05-29 | 2026-04-07 | Encoded Therapeutics, Inc. | Kompozycje i sposoby selektywnej regulacji genów |
| MX2022002980A (es) | 2019-09-16 | 2022-04-06 | Amgen Inc | Metodo para la esterilizacion externa de un dispositivo de suministro de farmacos. |
| US20230174612A1 (en) * | 2020-04-09 | 2023-06-08 | The Regents Of The University Of California | Notch receptors with zinc finger-containing transcriptional effector |
| EP4146684A2 (en) | 2020-05-08 | 2023-03-15 | Alpine Immune Sciences, Inc. | April and baff inhibitory immunomodulatory proteins with and without a t cell inhibitory protein and methods of use thereof |
| CN116802267A (zh) * | 2020-10-23 | 2023-09-22 | 斯宾德尔生物科技公司 | 用于rna合成的组合物和方法 |
| US20240366681A1 (en) | 2021-08-13 | 2024-11-07 | Triovance Holding Llc | A skin substitute composition and methods of producing and using the same |
| EP4698662A2 (en) * | 2023-04-17 | 2026-02-25 | AskBio Inc. | Regulatable controlled expression of a transgene in primates |
| CN117756945A (zh) * | 2023-11-14 | 2024-03-26 | 维康平生(北京)生物科技有限公司 | 融合蛋白及其用途 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US81614A (en) * | 1868-09-01 | Jacob erdle | ||
| US147327A (en) * | 1874-02-10 | Improvement in weft-stop mechanisms for looms | ||
| US182698A (en) * | 1876-09-26 | Improvement in machines for canceling postage-stamps and postmarking letters | ||
| US540065A (en) * | 1895-05-28 | Andrew kriegee | ||
| US2996496A (en) | 1956-06-22 | 1961-08-15 | Central Pharmacal Company | Calcium substitution products of dextran |
| US4394443A (en) | 1980-12-18 | 1983-07-19 | Yale University | Method for cloning genes |
| US4446235A (en) | 1982-03-22 | 1984-05-01 | Genentech, Inc. | Method for cloning human growth hormone varient genes |
| US4981784A (en) | 1987-12-02 | 1991-01-01 | The Salk Institute For Biological Studies | Retinoic acid receptor method |
| US5317090A (en) | 1987-12-16 | 1994-05-31 | Institut Pasteur | Steroid/thyroid hormone receptor-related gene, which is inappropriately expressed in human hepatocellular carcinoma, and which is a retinoic acid receptor |
| US5217867A (en) * | 1988-11-30 | 1993-06-08 | The Salk Institute For Biological Studies | Receptors: their identification, characterization, preparation and use |
| WO1990007517A1 (en) | 1988-12-23 | 1990-07-12 | The Salk Institute For Biological Studies | Receptor transcription-repression activity compositions and methods |
| US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
| US4990607A (en) | 1989-03-14 | 1991-02-05 | The Rockefeller University | Alteration of gene expression in plants |
| US5140466A (en) * | 1990-12-20 | 1992-08-18 | Hughes Aircraft Company | Optical multiplexer |
| US5364791A (en) | 1992-05-14 | 1994-11-15 | Elisabetta Vegeto | Progesterone receptor having C. terminal hormone binding domain truncations |
| US6416998B1 (en) | 1992-09-02 | 2002-07-09 | Baylor College Of Medicine | Plasmid encoding a modified steroid hormone |
| EP0745121B1 (en) | 1992-05-14 | 2007-06-20 | Baylor College Of Medicine | Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy |
| GB9214857D0 (en) * | 1992-07-13 | 1992-08-26 | Medical Res Council | Human nucleic acid fragments and their use |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US20050084885A1 (en) | 1994-01-18 | 2005-04-21 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US6242568B1 (en) | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| DE69534629D1 (de) | 1994-01-18 | 2005-12-29 | Scripps Research Inst | Derivate von zinkfingerproteinen und methoden |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US6723531B2 (en) | 1996-04-05 | 2004-04-20 | The Salk Institute For Biological Studies | Method for modulating expression of exogenous genes in mammalian systems, and products related thereto |
| EP0935657B1 (en) | 1996-10-29 | 2007-08-29 | Baylor College Of Medicine | Modified steroid hormone receptors |
| ES2341926T3 (es) | 1998-03-02 | 2010-06-29 | Massachusetts Institute Of Technology | Poliproteinas con dedos de cinc que tienen enlazadores mejorados. |
| US6140081A (en) * | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6599692B1 (en) | 1999-09-14 | 2003-07-29 | Sangamo Bioscience, Inc. | Functional genomics using zinc finger proteins |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US7329728B1 (en) * | 1999-10-25 | 2008-02-12 | The Scripps Research Institute | Ligand activated transcriptional regulator proteins |
| US7151201B2 (en) | 2000-01-21 | 2006-12-19 | The Scripps Research Institute | Methods and compositions to modulate expression in plants |
| AU2964101A (en) | 2000-01-21 | 2001-07-31 | Scripps Research Institute, The | Methods and compositions to modulate expression in plants |
| AU2001295193A1 (en) | 2000-05-01 | 2001-11-12 | Novartis Ag | Vectors for ocular transduction and use thereof for genetic therapy |
| IL153853A0 (en) | 2000-07-10 | 2003-07-31 | Novartis Ag | Bifunctional molecules and vectors complexed therewith for targeted gene delivery |
| US7011972B2 (en) | 2000-07-18 | 2006-03-14 | The Scripps Research Institute | Fusion polypeptide comprising two ligand binding domains |
| IL153833A0 (en) | 2000-07-18 | 2003-07-31 | Novartis Ag | Regulation of gene expression using single-chain, monomeric, ligand dependent polypeptide switches |
| NZ527476A (en) | 2001-02-21 | 2006-06-30 | Novartis Ag | Zinc finger binding domains for nucleotide sequence ANN |
| US7067617B2 (en) | 2001-02-21 | 2006-06-27 | The Scripps Research Institute | Zinc finger binding domains for nucleotide sequence ANN |
| EP1397382B1 (en) | 2001-05-31 | 2008-08-06 | Novartis AG | Novel estrogen receptor ligand binding domain variants and novel ligands and pharmaceutical compositions |
| JP2005500061A (ja) | 2001-08-20 | 2005-01-06 | ザ スクリップス リサーチ インスティテュート | Cnnについての亜鉛フィンガー結合ドメイン |
| EP1516055A4 (en) | 2002-01-24 | 2007-08-08 | Scripps Research Inst | FIBER OPERATING MODIFICATIONS FOR EFFICIENT TARGETS |
| US20060078880A1 (en) * | 2002-02-07 | 2006-04-13 | The Scripps Research Institute | Zinc finger libraries |
| US20060211846A1 (en) * | 2002-02-13 | 2006-09-21 | Barbas Carlos F Iii | Zinc finger binding domains for nucleotide sequence ANN |
| JP2006513694A (ja) | 2002-06-11 | 2006-04-27 | ザ スクリップス リサーチ インスティテュート | 人工転写因子 |
| PE20060574A1 (es) * | 2004-07-28 | 2006-06-24 | Glaxo Group Ltd | Derivados de arilpiperazina sulfonamida como agonistas de los receptores de secretagogos de la hormona del crecimiento (ghs) |
| EP2130838A3 (en) * | 2005-08-11 | 2010-04-07 | The Scripps Research Institute | Zinc finger binding domains for CNN |
| EP1963499A4 (en) * | 2005-11-28 | 2009-04-08 | Scripps Research Inst | ZINCFINGER BINDING DOMAIN FOR TNN |
| US20070154989A1 (en) * | 2006-01-03 | 2007-07-05 | The Scripps Research Institute | Zinc finger domains specifically binding agc |
| US8874746B1 (en) | 2010-05-24 | 2014-10-28 | Datacore Software Corporation | Collaboration between discrete systems and a shared system to consolidate shared storage-related services |
-
2000
- 2000-06-02 US US09/586,625 patent/US7329728B1/en not_active Expired - Fee Related
- 2000-10-23 CA CA002388535A patent/CA2388535A1/en not_active Abandoned
- 2000-10-23 JP JP2001533840A patent/JP2003512827A/ja not_active Withdrawn
- 2000-10-23 NZ NZ518218A patent/NZ518218A/en unknown
- 2000-10-23 AU AU11438/01A patent/AU775988B2/en not_active Ceased
- 2000-10-23 IL IL14914200A patent/IL149142A0/xx unknown
- 2000-10-23 WO PCT/EP2000/010430 patent/WO2001030843A1/en not_active Ceased
- 2000-10-23 EP EP00972849A patent/EP1226168A1/en not_active Ceased
-
2002
- 2002-04-15 IL IL149142A patent/IL149142A/en not_active IP Right Cessation
-
2003
- 2003-04-23 US US10/422,934 patent/US7442784B2/en not_active Expired - Fee Related
-
2008
- 2008-07-22 US US12/220,328 patent/US20080318839A1/en not_active Abandoned
-
2009
- 2009-06-22 JP JP2009147520A patent/JP2009273463A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2388535A1 (en) | 2001-05-03 |
| US7329728B1 (en) | 2008-02-12 |
| US20080318839A1 (en) | 2008-12-25 |
| AU1143801A (en) | 2001-05-08 |
| JP2003512827A (ja) | 2003-04-08 |
| WO2001030843A1 (en) | 2001-05-03 |
| NZ518218A (en) | 2004-04-30 |
| IL149142A (en) | 2010-05-31 |
| US20030186841A1 (en) | 2003-10-02 |
| EP1226168A1 (en) | 2002-07-31 |
| US7442784B2 (en) | 2008-10-28 |
| JP2009273463A (ja) | 2009-11-26 |
| AU775988B2 (en) | 2004-08-19 |
| WO2001030843A9 (en) | 2002-09-19 |
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| DE60004583D1 (de) | Regler | |
| GB9921125D0 (en) | Proteins | |
| GB9912572D0 (en) | Biological wound dresings | |
| EP1182524A4 (en) | PROGRAMMABLE CONTROL | |
| AU5623000A (en) | Human transcriptional regulator proteins | |
| GB9914465D0 (en) | Portable sensing devices | |
| GB0012707D0 (en) | Loading system | |
| GB9927681D0 (en) | Protein | |
| IL146891A0 (en) | Personalized metabrowser | |
| AU3628299A (en) | Transcriptional regulatory factor | |
| GB9918680D0 (en) | Polypeptide | |
| GB9924060D0 (en) | VIP54 protein | |
| IL150134A0 (en) | Apoptin-associating protein | |
| GB9723982D0 (en) | Reversible bracket | |
| EP1188828A4 (en) | REG-BINDING PROTEIN | |
| CA91111S (en) | Thermostat | |
| GB9927157D0 (en) | Releasable Ligand | |
| GB2356888B (en) | Former element | |
| PL110219U1 (en) | Portable dresser | |
| GB2347645B (en) | Book covering | |
| CA87190S (en) | Dresser | |
| GR20000200026U (en) | Portable vehicle-immobilising system | |
| GB9907805D0 (en) | Proteins |