IL149051A0 - Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition - Google Patents

Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition

Info

Publication number
IL149051A0
IL149051A0 IL14905100A IL14905100A IL149051A0 IL 149051 A0 IL149051 A0 IL 149051A0 IL 14905100 A IL14905100 A IL 14905100A IL 14905100 A IL14905100 A IL 14905100A IL 149051 A0 IL149051 A0 IL 149051A0
Authority
IL
Israel
Prior art keywords
triazines
pyrazolo
enhancing cognition
cognition
enhancing
Prior art date
Application number
IL14905100A
Other languages
English (en)
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9927874.9A external-priority patent/GB9927874D0/en
Priority claimed from GB0009602A external-priority patent/GB0009602D0/en
Priority claimed from GB0018651A external-priority patent/GB0018651D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of IL149051A0 publication Critical patent/IL149051A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14905100A 1999-11-25 2000-11-22 Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition IL149051A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9927874.9A GB9927874D0 (en) 1999-11-25 1999-11-25 Therapeutic agents
GB0009602A GB0009602D0 (en) 2000-04-18 2000-04-18 Therapeutic agents
GB0018651A GB0018651D0 (en) 2000-07-28 2000-07-28 Therapeutic agents
PCT/GB2000/004450 WO2001038331A2 (en) 1999-11-25 2000-11-22 Pyrazolo[1,5-d][1,2,4]triazines for enhancing cognition

Publications (1)

Publication Number Publication Date
IL149051A0 true IL149051A0 (en) 2002-11-10

Family

ID=27255677

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14905100A IL149051A0 (en) 1999-11-25 2000-11-22 Pyrazolo [1,5,-d] [1,2,4] triazines for enhancing cognition

Country Status (20)

Country Link
US (1) US6355638B1 (es)
EP (1) EP1235829A2 (es)
JP (1) JP2003514909A (es)
KR (1) KR20020053091A (es)
CN (1) CN1391574A (es)
AU (1) AU1533001A (es)
BG (1) BG106734A (es)
BR (1) BR0015126A (es)
CA (1) CA2391103A1 (es)
CZ (1) CZ20021813A3 (es)
EA (1) EA200200599A1 (es)
EE (1) EE200200260A (es)
HK (1) HK1046406A1 (es)
HU (1) HUP0203579A3 (es)
IL (1) IL149051A0 (es)
MX (1) MXPA02005233A (es)
NO (1) NO20022456L (es)
PL (1) PL355637A1 (es)
SK (1) SK8952002A3 (es)
WO (1) WO2001038331A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0128499D0 (en) * 2001-11-28 2002-01-23 Merck Sharp & Dohme Therapeutic agents
EP2298296A1 (en) * 2009-08-25 2011-03-23 CNRS Centre National De La Recherche Scientifique Composition and method for treating cognitive impairments in down syndrome subjects
WO2011150156A2 (en) * 2010-05-26 2011-12-01 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
US20150374705A1 (en) * 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
CN107344938B (zh) * 2016-05-06 2022-05-06 上海赛默罗生物科技有限公司 吡唑-三嗪类衍生物、其制备方法、药物组合物和用途
CN107344936B (zh) * 2016-05-06 2022-06-03 上海赛默罗生物科技有限公司 三唑哒嗪类衍生物、其制备方法、药物组合物和用途
US20230088214A1 (en) * 2019-06-19 2023-03-23 Biomarin Pharmaceutical Inc. Glycolate oxidase inhibitors for the treatment of disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA002436B1 (ru) * 1996-07-25 2002-04-25 Мерк Шарп Энд Домэ Лимитед Замещенные производные триазоло-пиридазина в качестве лигандов рецепторов гамк
GB9715977D0 (en) * 1997-07-29 1997-10-01 Merck Sharp & Dohme Therapeutic agents
AU746866B2 (en) * 1998-01-14 2002-05-02 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for GABA receptors
GB9806102D0 (en) * 1998-03-20 1998-05-20 Merck Sharp & Dohme Therapeutic agents
JP2002518391A (ja) * 1998-06-16 2002-06-25 メルク シャープ エンド ドーム リミテッド Ｇａｂａ受容体のリガンドとしてのトリアゾロ−ピリジン誘導体
DE69936998T2 (de) * 1998-10-16 2008-05-21 Merck Sharp & Dohme Ltd., Hoddesdon Pyrazolotriazinderivate als gaba-rezeptorliganden

Also Published As

Publication number Publication date
HK1046406A1 (zh) 2003-01-10
NO20022456D0 (no) 2002-05-24
EE200200260A (et) 2003-06-16
US6355638B1 (en) 2002-03-12
NO20022456L (no) 2002-05-24
BG106734A (en) 2003-02-28
WO2001038331A3 (en) 2001-11-08
EA200200599A1 (ru) 2002-12-26
CA2391103A1 (en) 2001-05-31
SK8952002A3 (en) 2002-10-08
HUP0203579A2 (hu) 2003-03-28
MXPA02005233A (es) 2002-11-07
CN1391574A (zh) 2003-01-15
CZ20021813A3 (cs) 2002-08-14
BR0015126A (pt) 2002-07-02
PL355637A1 (en) 2004-05-04
JP2003514909A (ja) 2003-04-22
AU1533001A (en) 2001-06-04
HUP0203579A3 (en) 2003-07-28
WO2001038331A2 (en) 2001-05-31
KR20020053091A (ko) 2002-07-04
EP1235829A2 (en) 2002-09-04

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