IL147194A0 - Thiophene a2a receptor agonists - Google Patents

Thiophene a2a receptor agonists

Info

Publication number
IL147194A0
IL147194A0 IL14719400A IL14719400A IL147194A0 IL 147194 A0 IL147194 A0 IL 147194A0 IL 14719400 A IL14719400 A IL 14719400A IL 14719400 A IL14719400 A IL 14719400A IL 147194 A0 IL147194 A0 IL 147194A0
Authority
IL
Israel
Prior art keywords
thiophene
receptor agonists
disclosed
purposes
alkylthienyl
Prior art date
Application number
IL14719400A
Other languages
English (en)
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Publication of IL147194A0 publication Critical patent/IL147194A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14719400A 1999-06-22 2000-06-20 Thiophene a2a receptor agonists IL147194A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14047899P 1999-06-22 1999-06-22
PCT/US2000/016856 WO2000078776A2 (en) 1999-06-22 2000-06-20 Thiophene a2a receptor agonists

Publications (1)

Publication Number Publication Date
IL147194A0 true IL147194A0 (en) 2002-08-14

Family

ID=22491411

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14719400A IL147194A0 (en) 1999-06-22 2000-06-20 Thiophene a2a receptor agonists
IL147194A IL147194A (en) 1999-06-22 2001-12-19 Derivatives of 2-traueril adenosine with agonist activity for A2A receptors and the pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL147194A IL147194A (en) 1999-06-22 2001-12-19 Derivatives of 2-traueril adenosine with agonist activity for A2A receptors and the pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US6440948B1 (es)
EP (1) EP1194441B1 (es)
JP (1) JP2003502434A (es)
KR (1) KR100463694B1 (es)
CN (1) CN1166677C (es)
AT (1) ATE252595T1 (es)
AU (1) AU768530B2 (es)
BR (1) BR0011853A (es)
CA (1) CA2373410C (es)
DE (1) DE60006116T2 (es)
ES (1) ES2206259T3 (es)
HK (1) HK1048821B (es)
IL (2) IL147194A0 (es)
MX (1) MXPA01013323A (es)
NO (1) NO20016242L (es)
NZ (1) NZ516336A (es)
TR (1) TR200200617T2 (es)
WO (1) WO2000078776A2 (es)
ZA (1) ZA200200299B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2264826T3 (es) * 1998-10-16 2007-01-16 Pfizer Inc. Derivados de adenina.
EP1764118B1 (en) 2002-02-15 2010-08-25 Gilead Palo Alto, Inc. Polymer coating for medical devices
TWI346109B (en) 2004-04-30 2011-08-01 Otsuka Pharma Co Ltd 4-amino-5-cyanopyrimidine derivatives
EA011826B1 (ru) 2004-05-26 2009-06-30 Инотек Фармасьютикалз Корпорейшн Пуриновые производные в качестве агонистов аденозиновых арецепторов и способы их применения
US7863253B2 (en) * 2004-09-20 2011-01-04 Inotek Pharmaceuticals Corporation Purine Derivatives and methods of use thereof
CA2627319A1 (en) * 2005-11-30 2007-06-07 Prakash Jagtap Purine derivatives and methods of use thereof
US8877732B2 (en) 2010-01-11 2014-11-04 Inotek Pharmaceuticals Corporation Combination, kit and method of reducing intraocular pressure
MX2012010724A (es) 2010-03-26 2012-11-12 Inotek Pharmaceuticals Corp Metodo para reducir la presion intraocular en seres humanos empleando n6-ciclopentiladenosina (cpa), derivados de cpa o profarmacos de los mismos.
DK2807178T3 (en) 2012-01-26 2017-09-04 Inotek Pharmaceuticals Corp Anhydrous polymorphs of (2R, 3S, 4R, 5R) -5- (6- (cyclopentylamino) -9H-purin-9-yl) -3,4-dihydroxytetrahydrofuran-2-yl) methyl nitrate and processes for their preparation
SG11201506882YA (en) 2013-03-15 2015-09-29 Inotek Pharmaceuticals Corp Ophthalmic formulations
US20210128699A1 (en) 2017-01-13 2021-05-06 Tobishi Pharmaceutical Co., Ltd. Neutrophil activation regulator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135130B (da) * 1970-12-28 1977-03-07 Takeda Chemical Industries Ltd Analogifremgangsmåde til fremstilling af 2-substituerede adenosinderivater eller syreadditionssalte deraf.
JPS4911896A (es) * 1972-05-15 1974-02-01
JPS5518625B2 (es) * 1973-07-26 1980-05-20
US5070877A (en) 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
HUT64967A (en) * 1991-04-06 1994-03-28 Fisons Plc Atp analogues and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
TR200200617T2 (tr) 2002-06-21
AU768530B2 (en) 2003-12-18
CN1364170A (zh) 2002-08-14
CA2373410C (en) 2006-08-29
CA2373410A1 (en) 2000-12-28
CN1166677C (zh) 2004-09-15
KR20020028912A (ko) 2002-04-17
NO20016242L (no) 2002-02-21
MXPA01013323A (es) 2003-10-15
HK1048821A1 (en) 2003-04-17
EP1194441B1 (en) 2003-10-22
WO2000078776A3 (en) 2001-06-28
NZ516336A (en) 2004-01-30
JP2003502434A (ja) 2003-01-21
WO2000078776A2 (en) 2000-12-28
EP1194441A2 (en) 2002-04-10
HK1048821B (zh) 2005-02-25
ZA200200299B (en) 2003-08-27
BR0011853A (pt) 2002-04-30
DE60006116T2 (de) 2004-07-08
ATE252595T1 (de) 2003-11-15
IL147194A (en) 2007-08-19
AU5625100A (en) 2001-01-09
US6440948B1 (en) 2002-08-27
ES2206259T3 (es) 2004-05-16
DE60006116D1 (de) 2003-11-27
KR100463694B1 (ko) 2004-12-29
NO20016242D0 (no) 2001-12-19

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Legal Events

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FF Patent granted
KB Patent renewed