TR200200617T2 - Tiofen A2a reseptör agonistleri. - Google Patents

Tiofen A2a reseptör agonistleri.

Info

Publication number
TR200200617T2
TR200200617T2 TR2002/00617T TR200200617T TR200200617T2 TR 200200617 T2 TR200200617 T2 TR 200200617T2 TR 2002/00617 T TR2002/00617 T TR 2002/00617T TR 200200617 T TR200200617 T TR 200200617T TR 200200617 T2 TR200200617 T2 TR 200200617T2
Authority
TR
Turkey
Prior art keywords
thiofen
receptor agonists
disclosed
purposes
alkylthienyl
Prior art date
Application number
TR2002/00617T
Other languages
English (en)
Inventor
A. Zablocki Jeffrey
O. Elzein Elfatih
P. Palle Venkata
Original Assignee
Cv Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics, Inc. filed Critical Cv Therapeutics, Inc.
Publication of TR200200617T2 publication Critical patent/TR200200617T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Formül (I)' e sahip 2-adenozin tiofen bilesikler: ve tedavi ve kalp görüntüleme amaçli olarak memelilerde koroner damar genislemesini uyarmak için bu bilesiklerin A2A reseptör agonistleri olarak kullanim yöntemleri.
TR2002/00617T 1999-06-22 2000-06-20 Tiofen A2a reseptör agonistleri. TR200200617T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14047899P 1999-06-22 1999-06-22

Publications (1)

Publication Number Publication Date
TR200200617T2 true TR200200617T2 (tr) 2002-06-21

Family

ID=22491411

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00617T TR200200617T2 (tr) 1999-06-22 2000-06-20 Tiofen A2a reseptör agonistleri.

Country Status (19)

Country Link
US (1) US6440948B1 (tr)
EP (1) EP1194441B1 (tr)
JP (1) JP2003502434A (tr)
KR (1) KR100463694B1 (tr)
CN (1) CN1166677C (tr)
AT (1) ATE252595T1 (tr)
AU (1) AU768530B2 (tr)
BR (1) BR0011853A (tr)
CA (1) CA2373410C (tr)
DE (1) DE60006116T2 (tr)
ES (1) ES2206259T3 (tr)
HK (1) HK1048821B (tr)
IL (2) IL147194A0 (tr)
MX (1) MXPA01013323A (tr)
NO (1) NO20016242L (tr)
NZ (1) NZ516336A (tr)
TR (1) TR200200617T2 (tr)
WO (1) WO2000078776A2 (tr)
ZA (1) ZA200200299B (tr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1121372B1 (en) * 1998-10-16 2006-06-28 Pfizer Limited Adenine derivatives
RU2308976C2 (ru) 2002-02-15 2007-10-27 Си Ви Терапьютикс, Инк. Полимерное покрытие для медицинских устройств
TWI346109B (en) * 2004-04-30 2011-08-01 Otsuka Pharma Co Ltd 4-amino-5-cyanopyrimidine derivatives
PL1758596T3 (pl) * 2004-05-26 2011-01-31 Inotek Pharmaceuticals Corp Pochodne purynowe jako agoniści receptora adenozynowgo A1, oraz sposoby ich zastosowania
BRPI0515506A (pt) * 2004-09-20 2008-07-29 Inotek Pharmaceuticals Corp derivados de purina e métodos de uso dos mesmos
CA2627319A1 (en) * 2005-11-30 2007-06-07 Prakash Jagtap Purine derivatives and methods of use thereof
ME02608B (me) 2010-01-11 2017-06-20 Inotek Pharmaceuticals Corp Kombinacija, komplet i postupak snižavanja intraokularnog pritiska
EP2569325A4 (en) 2010-03-26 2013-10-09 Inotek Pharmaceuticals Corp METHOD FOR REDUCING INTRAOCULAR PRESSURE IN HUMANS USING N6-CYCLOPENTYLADENOSINE (CPA) DERIVATIVES OR CPA PRODRUGS
SI2807178T1 (sl) 2012-01-26 2017-09-29 Inotek Pharmaceuticals Corporation Anhidridni polimorf (2R,3S,4R,5R)-5-(6-(ciklofentilamino)-9H-purin-9-il)-3,4-dihidroksite- trahidrofuran-2-il))metil nitrat in postopki njegove priprave
SG11201506882YA (en) 2013-03-15 2015-09-29 Inotek Pharmaceuticals Corp Ophthalmic formulations
WO2018131724A1 (en) 2017-01-13 2018-07-19 Tobishi Pharmaceutical Co., Ltd. Neutrophil activation regulator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135130B (da) * 1970-12-28 1977-03-07 Takeda Chemical Industries Ltd Analogifremgangsmåde til fremstilling af 2-substituerede adenosinderivater eller syreadditionssalte deraf.
JPS4911896A (tr) * 1972-05-15 1974-02-01
JPS5518625B2 (tr) * 1973-07-26 1980-05-20
US5070877A (en) 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
WO1992017488A1 (en) * 1991-04-06 1992-10-15 Fisons Plc Atp analogues

Also Published As

Publication number Publication date
DE60006116D1 (de) 2003-11-27
WO2000078776A3 (en) 2001-06-28
KR20020028912A (ko) 2002-04-17
NO20016242L (no) 2002-02-21
ATE252595T1 (de) 2003-11-15
HK1048821A1 (en) 2003-04-17
NZ516336A (en) 2004-01-30
KR100463694B1 (ko) 2004-12-29
DE60006116T2 (de) 2004-07-08
US6440948B1 (en) 2002-08-27
CA2373410C (en) 2006-08-29
ZA200200299B (en) 2003-08-27
WO2000078776A2 (en) 2000-12-28
BR0011853A (pt) 2002-04-30
EP1194441A2 (en) 2002-04-10
CN1166677C (zh) 2004-09-15
MXPA01013323A (es) 2003-10-15
CN1364170A (zh) 2002-08-14
NO20016242D0 (no) 2001-12-19
AU5625100A (en) 2001-01-09
IL147194A (en) 2007-08-19
ES2206259T3 (es) 2004-05-16
EP1194441B1 (en) 2003-10-22
IL147194A0 (en) 2002-08-14
JP2003502434A (ja) 2003-01-21
HK1048821B (zh) 2005-02-25
AU768530B2 (en) 2003-12-18
CA2373410A1 (en) 2000-12-28

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