IL146162A0 - Macrolide compounds for the treatment of dry eye - Google Patents

Macrolide compounds for the treatment of dry eye

Info

Publication number
IL146162A0
IL146162A0 IL14616200A IL14616200A IL146162A0 IL 146162 A0 IL146162 A0 IL 146162A0 IL 14616200 A IL14616200 A IL 14616200A IL 14616200 A IL14616200 A IL 14616200A IL 146162 A0 IL146162 A0 IL 146162A0
Authority
IL
Israel
Prior art keywords
treatment
dry eye
macrolide compounds
macrolide
compounds
Prior art date
Application number
IL14616200A
Other languages
English (en)
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22452015&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL146162(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Publication of IL146162A0 publication Critical patent/IL146162A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
IL14616200A 1999-04-30 2000-04-26 Macrolide compounds for the treatment of dry eye IL146162A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13200999P 1999-04-30 1999-04-30
PCT/JP2000/002756 WO2000066122A1 (en) 1999-04-30 2000-04-26 Use of macrolide compounds for the treatment of dry eye

Publications (1)

Publication Number Publication Date
IL146162A0 true IL146162A0 (en) 2002-07-25

Family

ID=22452015

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14616200A IL146162A0 (en) 1999-04-30 2000-04-26 Macrolide compounds for the treatment of dry eye

Country Status (23)

Country Link
EP (1) EP1173177B2 (de)
JP (2) JP5036934B2 (de)
KR (1) KR20020015316A (de)
CN (1) CN1190194C (de)
AR (1) AR023807A1 (de)
AT (1) ATE281167T1 (de)
AU (1) AU777915B2 (de)
BR (1) BR0011225A (de)
CA (1) CA2372448A1 (de)
CZ (1) CZ20013769A3 (de)
DE (1) DE60015516T2 (de)
ES (1) ES2232439T3 (de)
HK (2) HK1046099A1 (de)
HU (1) HUP0200864A3 (de)
IL (1) IL146162A0 (de)
MX (1) MXPA01010988A (de)
NO (1) NO20015288D0 (de)
NZ (1) NZ515339A (de)
PT (1) PT1173177E (de)
TR (1) TR200103119T2 (de)
TW (1) TWI230066B (de)
WO (1) WO2000066122A1 (de)
ZA (1) ZA200108905B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1190194C (zh) * 1999-04-30 2005-02-23 苏坎波公司 用于治疗干眼的大环内酯化合物的应用
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
CA2452372A1 (en) 2001-07-06 2003-01-16 Sucampo Ag Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent
AR035293A1 (es) * 2001-08-23 2004-05-05 Novartis Ag Composicion oftalmica.
PE20030828A1 (es) * 2002-03-04 2003-11-04 Novartis Ag Composicion oftalmica que comprende ascomicina
BR0313425A (pt) * 2002-08-09 2005-07-05 Sucampo Pharmaceuticals Inc Composição oftálmica para tratamento de alergia ocular, uso do composto de macrolìdeo e pacote comercial
US7354574B2 (en) 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
US20040198763A1 (en) * 2003-01-16 2004-10-07 Sucampo Ag Method of treating dry eye with a macrolide compound
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7083802B2 (en) 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
JP2007505932A (ja) 2003-09-18 2007-03-15 マクサイト, インコーポレイテッド 経強膜送達
US7083803B2 (en) 2003-09-19 2006-08-01 Advanced Ocular Systems Limited Ocular solutions
US7087237B2 (en) 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
WO2005032534A1 (ja) 2003-10-06 2005-04-14 Ophtecs Corporation 涙液異常の治療のための眼科用組成物
WO2006086750A1 (en) 2005-02-09 2006-08-17 Macusight, Inc. Liquid formulations for treatment of diseases or conditions
PL1904056T3 (pl) 2005-07-18 2009-09-30 Minu Llc Zastosowanie makrolidu do przywracania czucia rogówkowego
US8492400B2 (en) 2006-02-09 2013-07-23 Santen Pharmaceutical Co., Ltd. Stable formulations, and methods of their preparation and use
CN101443004B (zh) 2006-03-23 2013-03-06 参天制药株式会社 用于与血管通透性有关的疾病或病症的制剂
EP2335735A1 (de) * 2009-12-14 2011-06-22 Novaliq GmbH Pharmazeutische Zusammensetzung zur Behandlung von trockenem Auge
EP3630042A4 (de) * 2017-05-30 2021-06-23 Eximore Ltd. Zusammensetzungen und verfahren zur behandlung von trockenem auge mittels freisetzung von antibiotischem macrolid
WO2019060696A1 (en) 2017-09-25 2019-03-28 Surface Pharmaceuticals, Inc. OPTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR SURFACE DISEASE
CN113473970A (zh) 2018-12-27 2021-10-01 瑟菲斯眼科股份有限公司 用以治疗眼表疾病的眼科药物组合物和方法
WO2022240598A1 (en) 2021-05-10 2022-11-17 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain
US12440510B2 (en) 2021-05-10 2025-10-14 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66485B1 (en) * 1989-07-05 1996-01-10 Fujisawa Pharmaceutical Co Aqueous liquid composition for external use
ATE198708T1 (de) * 1991-04-26 2001-02-15 Fujisawa Pharmaceutical Co Verwendung von makrolid-verbindungen gegen augenerkrankungen
IL102414A (en) * 1991-07-25 1996-08-04 Univ Louisville Res Found Medicinal preparations for the treatment of ocular inflammation, containing rapamycin
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
WO1999051215A2 (en) * 1998-04-06 1999-10-14 Fujisawa Pharmaceutical Co., Ltd. Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins
WO1999055332A1 (en) * 1998-04-27 1999-11-04 Fujisawa Pharmaceutical Co., Ltd. Medicinal compositions
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
CN1190194C (zh) * 1999-04-30 2005-02-23 苏坎波公司 用于治疗干眼的大环内酯化合物的应用

Also Published As

Publication number Publication date
ES2232439T3 (es) 2005-06-01
KR20020015316A (ko) 2002-02-27
HK1046099A1 (zh) 2002-12-27
BR0011225A (pt) 2002-03-19
NO20015288L (no) 2001-10-29
JP2002543132A (ja) 2002-12-17
HK1043321B (en) 2005-07-15
PT1173177E (pt) 2005-03-31
JP2012116857A (ja) 2012-06-21
EP1173177A1 (de) 2002-01-23
AU777915B2 (en) 2004-11-04
EP1173177B2 (de) 2014-03-05
CA2372448A1 (en) 2000-11-09
TR200103119T2 (tr) 2002-04-22
HUP0200864A2 (hu) 2002-07-29
JP5036934B2 (ja) 2012-09-26
ATE281167T1 (de) 2004-11-15
CN1190194C (zh) 2005-02-23
ZA200108905B (en) 2002-12-24
AU4142900A (en) 2000-11-17
HK1043321A1 (en) 2002-09-13
AR023807A1 (es) 2002-09-04
MXPA01010988A (es) 2004-04-21
DE60015516D1 (de) 2004-12-09
CZ20013769A3 (cs) 2002-03-13
NZ515339A (en) 2004-02-27
EP1173177B1 (de) 2004-11-03
WO2000066122A1 (en) 2000-11-09
CN1353608A (zh) 2002-06-12
TWI230066B (en) 2005-04-01
DE60015516T2 (de) 2005-12-01
HUP0200864A3 (en) 2004-07-28
NO20015288D0 (no) 2001-10-29

Similar Documents

Publication Publication Date Title
HUP0200864A3 (en) Use of macrolide compounds for the treatment of dry eye
HRP20020253A2 (en) Compounds for the treatment of ischemia
DK1117401T3 (da) Antibiotisk præparat til øjenbehandling
IL196301A0 (en) Medicament for the treatment of hapatitis c
GB0013515D0 (en) Endoscope
IL151890A0 (en) Hydroxyphenyl-piperidin 4-ylidene-methyl-benzamide derivatives for the treatment of pain
GB9900150D0 (en) Treatment for fabrics
GB9800942D0 (en) Well treatment
GB9925136D0 (en) Novel treatment
IL151765A0 (en) Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
AU4498201A (en) Quinolinyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment ofpain
IL144186A0 (en) Novel treatment
IL133760A0 (en) Composition for the treatment of dandruff
GB9900151D0 (en) Treatment for fabrics
GB2363604B (en) S-nitrosothiols as agents for the treatment of circulatory dsyfunctions
GB9904252D0 (en) Composition for the treatment of pain
GB9927504D0 (en) Fabric treatment
GB9926985D0 (en) Use of substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides for the treatment of diseases
GB0206401D0 (en) Side effects treatment
GB9900149D0 (en) Treatment for fabrics
GB9919126D0 (en) Glaucoma treatment
GB9925550D0 (en) Glaucoma treatment
GB9908993D0 (en) Treatment
AU2002328886A1 (en) Insert for the treatment of dry eye
AUPQ282499A0 (en) Treatment of fabric