IL144874A0 - Thiophene-ethyl thiourea compounds and use in the treatment of hiv - Google Patents

Thiophene-ethyl thiourea compounds and use in the treatment of hiv

Info

Publication number
IL144874A0
IL144874A0 IL14487400A IL14487400A IL144874A0 IL 144874 A0 IL144874 A0 IL 144874A0 IL 14487400 A IL14487400 A IL 14487400A IL 14487400 A IL14487400 A IL 14487400A IL 144874 A0 IL144874 A0 IL 144874A0
Authority
IL
Israel
Prior art keywords
hiv
treatment
thiophene
thiourea compounds
ethyl thiourea
Prior art date
Application number
IL14487400A
Other languages
English (en)
Original Assignee
Parker Hughes Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parker Hughes Inst filed Critical Parker Hughes Inst
Publication of IL144874A0 publication Critical patent/IL144874A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14487400A 1999-06-23 2000-06-23 Thiophene-ethyl thiourea compounds and use in the treatment of hiv IL144874A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/338,685 US6124324A (en) 1999-06-23 1999-06-23 Thiophene-ethyl thiourea compounds and use
PCT/US2000/017361 WO2000078755A1 (en) 1999-06-23 2000-06-23 Thiophene-ethyl thiourea compounds and use in the treatment of hiv

Publications (1)

Publication Number Publication Date
IL144874A0 true IL144874A0 (en) 2002-06-30

Family

ID=23325726

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14487400A IL144874A0 (en) 1999-06-23 2000-06-23 Thiophene-ethyl thiourea compounds and use in the treatment of hiv

Country Status (14)

Country Link
US (1) US6124324A (xx)
EP (1) EP1194427B1 (xx)
JP (1) JP2003502423A (xx)
KR (1) KR20020012287A (xx)
CN (1) CN1196697C (xx)
AT (1) ATE233758T1 (xx)
AU (2) AU6539900A (xx)
BR (1) BR0009102A (xx)
CA (1) CA2375261A1 (xx)
DE (1) DE60001581T2 (xx)
ES (1) ES2195905T3 (xx)
IL (1) IL144874A0 (xx)
MX (1) MXPA01009283A (xx)
WO (2) WO2000078756A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001219672A1 (en) * 2000-10-18 2002-04-29 Parker Hughes Institute Phenoxyethyl-thiourea-pyridine compounds and their use for the treatment of hiv-infections
SE0100733D0 (sv) 2001-03-05 2001-03-05 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
SE0102867D0 (sv) 2001-08-28 2001-08-28 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
US7642277B2 (en) 2002-12-04 2010-01-05 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686428A (en) * 1989-04-07 1997-11-11 Aktiebolaget Astra Pharmaceutical composition
IL102548A (en) * 1991-08-02 1998-08-16 Medivir Ab Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds
US5593993A (en) * 1991-08-02 1997-01-14 Medivir Ab Method for inhibition of HIV related viruses

Also Published As

Publication number Publication date
AU5635800A (en) 2001-01-09
MXPA01009283A (es) 2002-04-10
WO2000078755A1 (en) 2000-12-28
EP1194427A1 (en) 2002-04-10
ES2195905T3 (es) 2003-12-16
DE60001581D1 (de) 2003-04-10
AU6539900A (en) 2001-01-09
WO2000078756A1 (en) 2000-12-28
DE60001581T2 (de) 2004-02-19
JP2003502423A (ja) 2003-01-21
ATE233758T1 (de) 2003-03-15
CN1356997A (zh) 2002-07-03
CA2375261A1 (en) 2000-12-28
EP1194427B1 (en) 2003-03-05
KR20020012287A (ko) 2002-02-15
BR0009102A (pt) 2002-01-08
CN1196697C (zh) 2005-04-13
US6124324A (en) 2000-09-26

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