IL142824A0 - Lipoic acid derivatives and their use in treatment of disease - Google Patents

Lipoic acid derivatives and their use in treatment of disease

Info

Publication number
IL142824A0
IL142824A0 IL14282499A IL14282499A IL142824A0 IL 142824 A0 IL142824 A0 IL 142824A0 IL 14282499 A IL14282499 A IL 14282499A IL 14282499 A IL14282499 A IL 14282499A IL 142824 A0 IL142824 A0 IL 142824A0
Authority
IL
Israel
Prior art keywords
disease
treatment
acid derivatives
lipoic acid
diseased cells
Prior art date
Application number
IL14282499A
Other languages
English (en)
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Publication of IL142824A0 publication Critical patent/IL142824A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
    • C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL14282499A 1998-10-26 1999-10-26 Lipoic acid derivatives and their use in treatment of disease IL142824A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10562898P 1998-10-26 1998-10-26
PCT/US1999/025140 WO2000024734A1 (en) 1998-10-26 1999-10-26 Lipoic acid derivatives and their use in treatment of disease

Publications (1)

Publication Number Publication Date
IL142824A0 true IL142824A0 (en) 2002-03-10

Family

ID=22306916

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14282499A IL142824A0 (en) 1998-10-26 1999-10-26 Lipoic acid derivatives and their use in treatment of disease
IL142824A IL142824A (en) 1998-10-26 2001-04-26 Lipoic acid derivatives and their use as anti metabolic agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142824A IL142824A (en) 1998-10-26 2001-04-26 Lipoic acid derivatives and their use as anti metabolic agents

Country Status (12)

Country Link
US (2) US6331559B1 (xx)
EP (3) EP1124820B1 (xx)
JP (2) JP4728481B2 (xx)
AT (2) ATE451362T1 (xx)
AU (1) AU774362B2 (xx)
BR (1) BR9914789A (xx)
CA (1) CA2348998C (xx)
DE (2) DE69920497T2 (xx)
ES (2) ES2229790T3 (xx)
IL (2) IL142824A0 (xx)
MX (1) MXPA01004152A (xx)
WO (1) WO2000024734A1 (xx)

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IT1319196B1 (it) * 2000-10-10 2003-09-26 Laboratorio Chimico Int Spa Sintesi dell'acido r(+)alfa-lipoico.
US7109362B2 (en) 2000-11-30 2006-09-19 Basf Aktiengesellschaft Process for the preparation of lipoic acid and dihydrolipoic acid
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US20040248982A1 (en) * 2003-06-09 2004-12-09 Dyer Gordon Wayne Use of compounds for the inhibition of proteins and UV protection
EP1651207A4 (en) * 2003-06-12 2008-10-01 Univ Colorado SYSTEMS AND METHOD FOR THE TREATMENT OF INFLAMMATORY AND PROLIFERATIVE DISEASES AND WOUNDS OF HUMANS WITH FATTY ACID SUBSTANCE CHEMICALS AND / OR GLYCOLYTIC INHIBITORS
WO2005070126A2 (en) * 2004-01-08 2005-08-04 The Regents Of The University Of Colorado Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors
US7129368B2 (en) * 2004-03-15 2006-10-31 Sonus Pharmaceuticals, Inc. Platinum carboxylate anticancer compounds
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EP1877060A2 (en) * 2005-04-28 2008-01-16 The Regents of the University of Colorado Therapeutic bifunctional compounds
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US20070225354A1 (en) * 2006-03-21 2007-09-27 Eric Marchewitz Use of dihydrolipoamide for enhancing physical performance
BRPI0810660A2 (pt) * 2007-04-18 2014-10-07 Cornerstone Pharmaceuticals Inc Derivados do ácido lipóico
NZ580973A (en) * 2007-04-18 2011-10-28 Cornerstone Pharmaceuticals Inc Pharmaceutical formulations containing lipoic acid derivatives
US8263653B2 (en) 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
CA2716321A1 (en) * 2008-02-21 2009-08-27 The Regents Of The University Of Colorado Methods for treating cancer using combination therapy
KR20110004846A (ko) * 2008-03-04 2011-01-14 로버트 쇼어 효소의 구조, 활성 및/또는 발현 정도의 조절
MX2010010713A (es) 2008-04-01 2011-02-21 Antipodean Pharmaceuticals Inc Composiciones y metodos para el cuidado de la piel.
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US9073985B2 (en) 2008-07-14 2015-07-07 The Regents Of The University Of Colorado, A Body Corporate Methods and products for treating proliferative diseases
WO2010019225A1 (en) * 2008-08-15 2010-02-18 Robert Shorr Pharmaceutical composition
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WO2010110887A1 (en) * 2009-03-24 2010-09-30 Robert Shorr Fatty acids
WO2010110771A2 (en) * 2009-03-25 2010-09-30 Frank Gibson Substituted thiol-containing alkyl fatty acids and process for synthesizing derivatives thereof
WO2011046583A1 (en) * 2009-09-11 2011-04-21 Robert Shorr Pharmaceutical exploitation of oxidative stress in transformed cells
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Also Published As

Publication number Publication date
US6951887B2 (en) 2005-10-04
DE69920497T2 (de) 2006-02-09
EP2145883A1 (en) 2010-01-20
JP4728481B2 (ja) 2011-07-20
ES2340488T3 (es) 2010-06-04
EP1124820B1 (en) 2004-09-22
AU1324600A (en) 2000-05-15
CA2348998C (en) 2012-03-06
AU774362B2 (en) 2004-06-24
ATE451362T1 (de) 2009-12-15
US6331559B1 (en) 2001-12-18
DE69941800D1 (de) 2010-01-21
DE69920497D1 (de) 2004-10-28
US20020107234A1 (en) 2002-08-08
JP5727721B2 (ja) 2015-06-03
CA2348998A1 (en) 2000-05-04
EP1486495A1 (en) 2004-12-15
WO2000024734A1 (en) 2000-05-04
ATE277034T1 (de) 2004-10-15
IL142824A (en) 2010-11-30
EP1124820A1 (en) 2001-08-22
ES2229790T3 (es) 2005-04-16
JP2002528446A (ja) 2002-09-03
BR9914789A (pt) 2001-10-02
JP2010248203A (ja) 2010-11-04
MXPA01004152A (es) 2002-06-04
EP1486495B1 (en) 2009-12-09

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