IL139863A0 - 3,4-diphenyl bicyclo [4.3.0] nonyl derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

3,4-diphenyl bicyclo [4.3.0] nonyl derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL139863A0
IL139863A0 IL13986399A IL13986399A IL139863A0 IL 139863 A0 IL139863 A0 IL 139863A0 IL 13986399 A IL13986399 A IL 13986399A IL 13986399 A IL13986399 A IL 13986399A IL 139863 A0 IL139863 A0 IL 139863A0
Authority
IL
Israel
Prior art keywords
preparation
methods
pharmaceutical compositions
same
compositions containing
Prior art date
Application number
IL13986399A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL139863A0 publication Critical patent/IL139863A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/16Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/24All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
IL13986399A 1998-06-09 1999-06-09 3,4-diphenyl bicyclo [4.3.0] nonyl derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same IL139863A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19826213A DE19826213A1 (de) 1998-06-09 1998-06-09 Neue Antiestrogene, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
PCT/EP1999/004049 WO1999064393A1 (de) 1998-06-09 1999-06-09 Neue antiestrogene, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
IL139863A0 true IL139863A0 (en) 2002-02-10

Family

ID=7870694

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13986399A IL139863A0 (en) 1998-06-09 1999-06-09 3,4-diphenyl bicyclo [4.3.0] nonyl derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same

Country Status (21)

Country Link
US (3) US6166075A (es)
EP (1) EP1086077B1 (es)
JP (1) JP2002517482A (es)
KR (1) KR20010052688A (es)
CN (1) CN1305457A (es)
AR (1) AR023629A1 (es)
AT (1) ATE263755T1 (es)
AU (1) AU759942B2 (es)
BR (1) BR9911103A (es)
CA (1) CA2334780A1 (es)
CO (1) CO5050355A1 (es)
DE (2) DE19826213A1 (es)
DK (1) DK1086077T3 (es)
ES (1) ES2220072T3 (es)
HU (1) HUP0102211A3 (es)
IL (1) IL139863A0 (es)
PE (1) PE20000541A1 (es)
PL (1) PL344309A1 (es)
PT (1) PT1086077E (es)
WO (1) WO1999064393A1 (es)
ZA (1) ZA200100201B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826213A1 (de) * 1998-06-09 1999-12-16 Schering Ag Neue Antiestrogene, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
US6525069B1 (en) 1998-12-18 2003-02-25 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
DE10039199A1 (de) * 2000-08-10 2002-02-21 Schering Ag Kombinationspräparate aus einem ERß selektiven Estrogen und einem SERM oder Antiestrogen
WO2002064142A1 (en) * 2001-02-15 2002-08-22 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with antiestrogen agents
DE10142881A1 (de) * 2001-09-03 2003-04-03 Jomed Gmbh Implantate mit Combretastatin A-4 (CA4)
US7183445B2 (en) 2003-05-31 2007-02-27 Janssen Pharmaceutica N.V Cyclohexyl derivatives as selective estrogen receptor modulators
US7750631B2 (en) * 2007-06-22 2010-07-06 Morpho Detection, Inc. Passenger inspection system and methods for using the same
US20090234024A1 (en) 2008-02-04 2009-09-17 Hooman Shadnia Estrogenic compounds, process for their production and pharmaceutical uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
FR2685332A1 (fr) * 1991-12-20 1993-06-25 Roussel Uclaf Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments.
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
FR2744445B1 (fr) * 1996-02-01 1998-10-02 Roussel Uclaf Composes biphenyles nouveaux et/ou a titre de medicament, compositions pharmaceutiques les contenant, leur procede de preparation et les intermediaires de ce procede
DE19826213A1 (de) * 1998-06-09 1999-12-16 Schering Ag Neue Antiestrogene, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung

Also Published As

Publication number Publication date
US6166075A (en) 2000-12-26
BR9911103A (pt) 2001-03-06
ES2220072T3 (es) 2004-12-01
CO5050355A1 (es) 2001-06-27
AR023629A1 (es) 2002-09-04
KR20010052688A (ko) 2001-06-25
EP1086077A1 (de) 2001-03-28
AU759942B2 (en) 2003-05-01
PL344309A1 (en) 2001-10-22
ZA200100201B (en) 2002-01-08
EP1086077B1 (de) 2004-04-07
WO1999064393A1 (de) 1999-12-16
HUP0102211A3 (en) 2002-12-28
CA2334780A1 (en) 1999-12-16
CN1305457A (zh) 2001-07-25
HUP0102211A2 (hu) 2002-03-28
ATE263755T1 (de) 2004-04-15
US6559181B1 (en) 2003-05-06
PT1086077E (pt) 2004-08-31
AU4771699A (en) 1999-12-30
DK1086077T3 (da) 2004-08-02
PE20000541A1 (es) 2000-08-10
US20030162830A1 (en) 2003-08-28
DE59909123D1 (de) 2004-05-13
DE19826213A1 (de) 1999-12-16
US7074829B2 (en) 2006-07-11
JP2002517482A (ja) 2002-06-18

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