IL136462A0 - Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases - Google Patents

Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases

Info

Publication number
IL136462A0
IL136462A0 IL13646298A IL13646298A IL136462A0 IL 136462 A0 IL136462 A0 IL 136462A0 IL 13646298 A IL13646298 A IL 13646298A IL 13646298 A IL13646298 A IL 13646298A IL 136462 A0 IL136462 A0 IL 136462A0
Authority
IL
Israel
Prior art keywords
combination
proliferative diseases
antineoplastic drugs
treating proliferative
benzocycloheptapyridine
Prior art date
Application number
IL13646298A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27385940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL136462(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL136462A0 publication Critical patent/IL136462A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13646298A 1997-12-22 1998-12-21 Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases IL136462A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99602797A 1997-12-22 1997-12-22
US14352998A 1998-08-28 1998-08-28
US18196998A 1998-10-29 1998-10-29
PCT/US1998/026224 WO1999032114A1 (en) 1997-12-22 1998-12-21 Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases

Publications (1)

Publication Number Publication Date
IL136462A0 true IL136462A0 (en) 2001-06-14

Family

ID=27385940

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13646298A IL136462A0 (en) 1997-12-22 1998-12-21 Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases

Country Status (25)

Country Link
EP (1) EP1041985B1 (es)
JP (1) JP4502503B2 (es)
KR (1) KR100700907B1 (es)
CN (1) CN1129431C (es)
AR (1) AR017440A1 (es)
AT (1) ATE317697T1 (es)
AU (1) AU756762B2 (es)
BR (1) BR9814419A (es)
CA (1) CA2315693C (es)
CL (1) CL2007001889A1 (es)
CO (1) CO5080764A1 (es)
CZ (1) CZ298511B6 (es)
DE (1) DE69833509T2 (es)
DK (1) DK1041985T3 (es)
ES (1) ES2255196T3 (es)
HU (1) HUP0102473A3 (es)
IL (1) IL136462A0 (es)
MY (1) MY137303A (es)
NO (1) NO326832B1 (es)
NZ (1) NZ504928A (es)
PE (1) PE20000042A1 (es)
PT (1) PT1041985E (es)
SK (1) SK285584B6 (es)
TW (1) TW581763B (es)
WO (1) WO1999032114A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787327B1 (fr) * 1998-12-21 2003-01-17 Aventis Pharma Sa Compositions contenant des inhibiteurs de farnesyle transferase
RU2298417C2 (ru) * 1999-11-09 2007-05-10 Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик (С.К.Р.А.С.) Продукт, включающий ингибитор трансдукции сигналов гетеротримерных протеинов g в комбинации с другим цитостатическим средством, для терапевтического применения при лечении рака
WO2001045740A2 (en) * 1999-12-22 2001-06-28 The Government Of The United States, Department Of Health And Human Services Compositions and methods for treatment of breast cancer
AU2001256166A1 (en) * 2000-02-29 2001-09-12 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives
JP2003525236A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ビンカアルカロイドとのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
WO2001064197A2 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
CA2397446A1 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica Inc. Combinations of a farnesyl protein transferase inhibitor with nitrogen mustard or nitrosourea alkylating agents
JP2003525246A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 白金化合物とのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
AU2001239275A1 (en) * 2000-02-29 2001-09-12 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives
TWI310684B (en) 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
WO2002056884A2 (en) * 2001-01-22 2002-07-25 Schering Corporation Treatment of malaria with farnesyl protein transferase inhibitors
DE60230017D1 (de) * 2001-02-15 2009-01-08 Janssen Pharmaceutica Nv Farnesyl-protein-transferase hemmer in kombination mit antiöstrogenen
US20030185831A1 (en) * 2001-11-30 2003-10-02 Schering Corporation Methods of treating cancer using an FPT inhibitor and antineoplastic
CN1849122A (zh) * 2001-12-03 2006-10-18 先灵公司 Fpt抑制剂与至少两种抗肿瘤药在治疗癌症中的用途
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
CN105198758A (zh) * 2015-09-22 2015-12-30 湖南大学 一种高纯度(z)-他莫昔酚的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
EP0563134B1 (en) * 1990-12-18 1996-06-19 The Wellcome Foundation Limited Agents for potentiating the effects of antitumor agents and combating multiple drug resistance
JP2767176B2 (ja) * 1992-12-15 1998-06-18 大塚製薬株式会社 抗癌剤
US5637688A (en) * 1994-12-13 1997-06-10 Eli Lilly And Company Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride
WO1997005902A1 (fr) * 1995-08-09 1997-02-20 Banyu Pharmaceutical Co., Ltd. Composition medicinale
AU730194B2 (en) * 1995-12-22 2001-03-01 Merck Sharp & Dohme Corp. Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative diseases
PL189698B1 (pl) * 1996-03-12 2005-09-30 Pg Txl Co Kompozycja farmaceutyczna zawierająca lek przeciwnowotworowy i jej zastosowania
JP2000507584A (ja) * 1996-04-03 2000-06-20 メルク エンド カンパニー インコーポレーテッド ファルネシル―タンパク質転移酵素の阻害剤
WO1997038697A1 (en) * 1996-04-15 1997-10-23 The Trustees Of The University Of Pennsylvania Sensitization of cells to radiation and chemotherapy
CA2251955A1 (en) * 1996-04-18 1997-10-23 Nancy E. Kohl A method of treating cancer
EP0934270A1 (en) * 1996-05-30 1999-08-11 Merck & Co., Inc. A method of treating cancer
WO1998032376A1 (en) * 1997-01-29 1998-07-30 Picker Medical Systems, Ltd. Predictive bolus tracking
SK285969B6 (sk) * 1997-02-18 2007-12-06 Canji, Inc. Prípravky na liečenie cicavčích nádorových alebo hyperproliferatívnych buniek

Also Published As

Publication number Publication date
BR9814419A (pt) 2000-10-10
CA2315693A1 (en) 1999-07-01
SK285584B6 (sk) 2007-04-05
PE20000042A1 (es) 2000-02-17
EP1041985A1 (en) 2000-10-11
CO5080764A1 (es) 2001-09-25
CA2315693C (en) 2010-11-30
CZ20002236A3 (cs) 2001-04-11
CL2007001889A1 (es) 2008-01-11
NO20003229D0 (no) 2000-06-21
MY137303A (en) 2009-01-30
KR20010033452A (ko) 2001-04-25
TW581763B (en) 2004-04-01
KR100700907B1 (ko) 2007-03-29
AU1907299A (en) 1999-07-12
DK1041985T3 (da) 2006-06-19
EP1041985B1 (en) 2006-02-15
HUP0102473A3 (en) 2003-07-28
CZ298511B6 (cs) 2007-10-24
DE69833509T2 (de) 2006-10-26
HUP0102473A2 (hu) 2002-01-28
ES2255196T3 (es) 2006-06-16
SK8982000A3 (en) 2001-04-09
NZ504928A (en) 2004-12-24
JP2001526224A (ja) 2001-12-18
CN1284875A (zh) 2001-02-21
AU756762B2 (en) 2003-01-23
PT1041985E (pt) 2006-07-31
AR017440A1 (es) 2001-09-05
DE69833509D1 (de) 2006-04-20
WO1999032114A1 (en) 1999-07-01
NO326832B1 (no) 2009-02-23
JP4502503B2 (ja) 2010-07-14
CN1129431C (zh) 2003-12-03
NO20003229L (no) 2000-08-22
ATE317697T1 (de) 2006-03-15

Similar Documents

Publication Publication Date Title
AP9700939A0 (en) Compounds and methods for the treatment of cancer
ZA971937B (en) Combinations for treatment of proliferative diseases.
PL330814A1 (en) Compounds for and methods of delivering pharmaceutical preparations and their application
AU2072201A (en) Agents and methods for the treatment of proliferative diseases
IL136462A0 (en) Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases
EP1077704A4 (en) COMBINATION THERAPY FOR TREATING DEPRESSION
GB9812056D0 (en) Pharmaceutical composition for treatment of ibd and rbd
HK1042825A1 (zh) 治療氣道疾病的化合物和方法以及氣道藥物的給藥方法
IL136515A0 (en) Combination effective for the treatment of impotence
HUP0100012A3 (en) Use for macrolides for the treatment of cancer and macular degeneration
ZA989556B (en) Benzoxazine derivatives their preparation and their therapeutic application
IL211081A0 (en) Methods and devices for providing prolonged drug therapy
IL127739A0 (en) Retinoyloxy (substituted) alkylene butyrates useful for the treatment of cancer and other proliferative diseases
HK1063004A1 (en) Oxalatoplatin and 5-fluorouracil for combination therapy of cancer
GB9808936D0 (en) Combination therapy for the prevention and treatment of osteoporosis
HUP0001263A3 (en) Methods of therapeutic administration of anti-cd4ol compounds
IL115320A0 (en) Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
AU7105498A (en) Combination therapy for the prevention and treatment of osteoporosis
IL121329A0 (en) A pharmaceutical composition for the treatment of cancer
HUP9904173A3 (en) Pharmaceutical composition for treating viral diseases
GB2344586B (en) Isoquinuclidine derivatives,method of manufacturing the same and therapeutic agents for hypercholesterolemia containing these compounds
SG65766A1 (en) Composition for preventing and treating gingival diseases
ZA984650B (en) Intratumoral administration of triphenylethylenes for the treatment of cancer
AU6126498A (en) Method for the treatment of drug addiction and homeopathic remedy
KR100248098B1 (en) Pharmaceutical composition for the treatment of dementia