IL136314A0 - Integrin receptor antagonists - Google Patents
Integrin receptor antagonistsInfo
- Publication number
- IL136314A0 IL136314A0 IL13631498A IL13631498A IL136314A0 IL 136314 A0 IL136314 A0 IL 136314A0 IL 13631498 A IL13631498 A IL 13631498A IL 13631498 A IL13631498 A IL 13631498A IL 136314 A0 IL136314 A0 IL 136314A0
- Authority
- IL
- Israel
- Prior art keywords
- beta
- alpha
- receptor antagonists
- integrin receptor
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Vending Machines For Individual Products (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6991097P | 1997-12-17 | 1997-12-17 | |
US7919798P | 1998-03-24 | 1998-03-24 | |
US7994498P | 1998-03-30 | 1998-03-30 | |
US8039798P | 1998-04-02 | 1998-04-02 | |
US8325198P | 1998-04-27 | 1998-04-27 | |
GBGB9810182.7A GB9810182D0 (en) | 1998-05-13 | 1998-05-13 | Vitronectin receptor antagonists |
GBGB9810882.2A GB9810882D0 (en) | 1998-05-20 | 1998-05-20 | Vitronectin receptor antagonists |
GBGB9810892.1A GB9810892D0 (en) | 1998-05-20 | 1998-05-20 | Vitronectin receptor antagonists |
GBGB9811283.2A GB9811283D0 (en) | 1998-05-26 | 1998-05-26 | Vironectin receptor antagonists |
GBGB9812686.5A GB9812686D0 (en) | 1998-06-12 | 1998-06-12 | Vitronectin receptor antagonists |
US9262498P | 1998-07-13 | 1998-07-13 | |
US9258898P | 1998-07-13 | 1998-07-13 | |
US9994898P | 1998-09-11 | 1998-09-11 | |
GBGB9822331.6A GB9822331D0 (en) | 1998-10-13 | 1998-10-13 | Vitronectin receptor antagonists |
GBGB9822701.0A GB9822701D0 (en) | 1998-10-16 | 1998-10-16 | Intergrin receptor antagonists |
PCT/US1998/026568 WO1999031099A1 (en) | 1997-12-17 | 1998-12-14 | Integrin receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
IL136314A0 true IL136314A0 (en) | 2001-05-20 |
Family
ID=27585232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13631498A IL136314A0 (en) | 1997-12-17 | 1998-12-14 | Integrin receptor antagonists |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1040111B1 (ru) |
JP (2) | JP3589633B2 (ru) |
KR (2) | KR20030048081A (ru) |
AT (1) | ATE298338T1 (ru) |
AU (1) | AU741769B2 (ru) |
BG (1) | BG104601A (ru) |
CA (1) | CA2315189C (ru) |
DK (1) | DK1040111T3 (ru) |
EA (1) | EA003095B1 (ru) |
EE (1) | EE200000360A (ru) |
ES (1) | ES2243016T3 (ru) |
HU (1) | HUP0100178A3 (ru) |
IL (1) | IL136314A0 (ru) |
IS (1) | IS5513A (ru) |
NO (1) | NO317975B1 (ru) |
NZ (1) | NZ504896A (ru) |
PE (1) | PE20000010A1 (ru) |
PL (1) | PL341095A1 (ru) |
PT (1) | PT1040111E (ru) |
SI (1) | SI1040111T1 (ru) |
SK (1) | SK9162000A3 (ru) |
TR (1) | TR200001752T2 (ru) |
WO (1) | WO1999031099A1 (ru) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1047425A4 (en) * | 1997-12-17 | 2009-04-22 | Merck & Co Inc | INTEGRIN RECEPTOR ANTAGONISTS |
GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
GB9814414D0 (en) | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
WO2000009503A1 (en) * | 1998-08-13 | 2000-02-24 | Merck & Co., Inc. | Integrin receptor antagonists |
GB9821061D0 (en) | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
EP1140183A1 (en) * | 1998-12-23 | 2001-10-10 | G.D. Searle & Co. | Use of a matrix metalloproteinase inhibitor and an integrin antagonist in the treatment of neoplasia |
CN1353706A (zh) | 1999-04-13 | 2002-06-12 | 巴斯福股份公司 | 整合素受体配体 |
US6518283B1 (en) | 1999-05-28 | 2003-02-11 | Celltech R&D Limited | Squaric acid derivatives |
IL146378A0 (en) | 1999-06-02 | 2002-07-25 | Merck & Co Inc | Alpha v integrin receptor antagonists |
DE19936780A1 (de) * | 1999-08-09 | 2001-02-15 | Basf Ag | Neue Antagonisten von Integrinrezeptoren |
US6534513B1 (en) | 1999-09-29 | 2003-03-18 | Celltech R&D Limited | Phenylalkanoic acid derivatives |
JP2003510360A (ja) * | 1999-10-04 | 2003-03-18 | メルク エンド カムパニー インコーポレーテッド | インテグリン受容体拮抗薬 |
ES2202191T3 (es) * | 1999-11-08 | 2004-04-01 | MERCK & CO., INC. | Procedimiento y productos intermedios para la preparacion de antagonistas de la imidazolidinona-alfa v-integrina. |
US6407241B1 (en) | 1999-11-08 | 2002-06-18 | Merck & Co., Inc. | Process and intermediates for the preparation of imidazolidinone αv integrin antagonists |
GB2356630A (en) | 1999-11-10 | 2001-05-30 | Merck & Co Inc | Intermediates used in the preparation of tetrahydronaphthyridine |
ATE258177T1 (de) | 1999-11-23 | 2004-02-15 | Merck & Co Inc | Verfahren für die herstellung und zwischenprodukte von tetrahydro-(1,8)- naphthyridin |
US6849639B2 (en) | 1999-12-14 | 2005-02-01 | Amgen Inc. | Integrin inhibitors and their methods of use |
US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
JP4787447B2 (ja) * | 2000-01-20 | 2011-10-05 | メルク・シャープ・エンド・ドーム・コーポレイション | αvインテグリン受容体拮抗薬 |
WO2001079173A2 (en) | 2000-04-17 | 2001-10-25 | Celltech R & D Limited | Enamine derivatives as cell adhesion molecules |
US6545013B2 (en) | 2000-05-30 | 2003-04-08 | Celltech R&D Limited | 2,7-naphthyridine derivatives |
US6403608B1 (en) | 2000-05-30 | 2002-06-11 | Celltech R&D, Ltd. | 3-Substituted isoquinolin-1-yl derivatives |
EP1301488A1 (en) | 2000-07-07 | 2003-04-16 | Celltech R&D Limited | Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists |
AU2001275724A1 (en) | 2000-08-02 | 2002-02-13 | Celltech R&D Limited | 3-substituted isoquinolin-1-yl derivatives |
AU9088401A (en) * | 2000-09-13 | 2002-03-26 | Merck & Co Inc | Alpha v integrin receptor antagonists |
AU2001292598B2 (en) | 2000-09-14 | 2006-06-29 | Merck & Co., Inc. | Alpha V integrin receptor antagonists |
WO2002053099A2 (en) * | 2001-01-03 | 2002-07-11 | Merck & Co., Inc. | Methods and compositions for treating periodontal disease |
ES2200617B1 (es) | 2001-01-19 | 2005-05-01 | Almirall Prodesfarma, S.A. | Derivados de urea como antagonistas de integrinas alfa 4. |
RU2316337C2 (ru) | 2001-04-24 | 2008-02-10 | Мерк Патент Гмбх | КОМБИНИРОВАННАЯ ТЕРАПИЯ, ИСПОЛЬЗУЮЩАЯ АНТИАНГИОГЕННЫЕ СРЕДСТВА И TNF-α |
US6855724B2 (en) | 2002-04-08 | 2005-02-15 | Agouron Pharmaceuticals, Inc. | Tropane derivatives useful in therapy |
UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
US20070299114A1 (en) * | 2004-10-05 | 2007-12-27 | Shionogi & Co., Ltd. | Biaryl Derivatives |
EP2338518A1 (en) | 2006-01-18 | 2011-06-29 | Merck Patent GmbH | Specific therapy using integrin ligands for treating cancer |
DE102006024024A1 (de) | 2006-05-23 | 2007-11-29 | Bayer Healthcare Aktiengesellschaft | Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung |
BRPI0806596A2 (pt) | 2007-01-18 | 2013-07-23 | Merck Patent Ges Mit Berchraenkter Haftung | medicamento e terapia especÍfica usando-se ligantes de integrina para o tratamento de cÂncer |
AU2009223235B2 (en) * | 2008-03-14 | 2014-09-11 | Merck Sharp & Dohme Corp. | Integrin targeting agents and in-vivo and in-vitro imaging methods using the same |
DE102008060967A1 (de) | 2008-12-06 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Phenylsulfonyltriazolone und ihre Verwendung |
DE102010001064A1 (de) | 2009-03-18 | 2010-09-23 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung |
MX2011012491A (es) | 2009-05-25 | 2011-12-14 | Merck Patent Gmbh | Administracion continua de cilengitida en tratamientos contra el cancer. |
UA109650C2 (xx) | 2010-02-27 | 2015-09-25 | Біс-арилзв'язані арилтриазолони та їх застосування | |
DE102010040187A1 (de) | 2010-09-02 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Substituierte N-Phenethyl-triazolonacetamide und ihre Verwendung |
DE102010040924A1 (de) | 2010-09-16 | 2012-03-22 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Phenylacet- und Phenylpropanamide und ihre Verwendung |
US8901144B2 (en) * | 2013-02-07 | 2014-12-02 | Scifluor Life Sciences, Llc | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives |
RU2698195C2 (ru) * | 2013-02-07 | 2019-08-23 | Сайфлуор Лайф Сайенсиз, Инк | Фторсодержащие антагонисты интегрина |
RS62591B1 (sr) | 2013-09-24 | 2021-12-31 | Fujifilm Corp | Novo jedinjenje koje sadrži azot ili njegova so ili njihov kompleks sa metalom |
BR112016027778A2 (pt) | 2014-05-30 | 2017-08-15 | Pfizer | Usos de derivados de carbonitrila, sua combinação e sua composição farmacêutica |
PL3215498T3 (pl) | 2014-11-03 | 2019-02-28 | Bayer Pharma Aktiengesellschaft | Pochodne fenylotriazolu podstawione hydroksyalkilem i ich zastosowania |
EP3259271B1 (en) * | 2015-02-19 | 2021-05-05 | SciFluor Life Sciences, Inc. | Fluorinated derivatives of 3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoic acid and uses thereof |
WO2017189828A1 (en) * | 2016-04-27 | 2017-11-02 | Scifluor Life Sciences, Inc. | Nonanoic and decanoic acid derivatives and uses thereof |
US9988367B2 (en) | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
EP4147698A1 (en) | 2017-02-28 | 2023-03-15 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
MX2019010267A (es) | 2017-02-28 | 2020-02-05 | Morphic Therapeutic Inc | INHIBIDORES DE INTEGRINA AVß6. |
BR112021003859A2 (pt) | 2018-08-29 | 2021-05-18 | Morphic Therapeutic, Inc. | inibindo integrina avss6 |
WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1598073A (en) * | 1976-12-18 | 1981-09-16 | Beecham Group Ltd | 8,10,12-triazaprostaglandins |
AU4806879A (en) * | 1978-06-15 | 1979-12-20 | Beecham Group Limited | 1,2,4 triazole derivatives |
DE3042466A1 (de) * | 1980-11-11 | 1982-06-16 | A. Nattermann & Cie GmbH, 5000 Köln | N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
EP0531382A1 (en) * | 1990-05-25 | 1993-03-17 | G.D. Searle & Co. | N-substituted-1,2,4-triazolone compounds for treatment of cardiovascular disorders |
US5416099A (en) * | 1991-10-29 | 1995-05-16 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
JP2001527506A (ja) * | 1992-02-11 | 2001-12-25 | スミスクライン・ビーチャム・コーポレイション | CoA−ITおよびPAF阻害剤 |
JPH10501222A (ja) * | 1994-05-27 | 1998-02-03 | メルク エンド カンパニー インコーポレーテッド | 破骨細胞仲介骨吸収を抑制するための化合物 |
-
1998
- 1998-12-14 IL IL13631498A patent/IL136314A0/xx unknown
- 1998-12-14 WO PCT/US1998/026568 patent/WO1999031099A1/en active IP Right Grant
- 1998-12-14 EA EA200000653A patent/EA003095B1/ru not_active IP Right Cessation
- 1998-12-14 KR KR10-2003-7005778A patent/KR20030048081A/ko not_active Application Discontinuation
- 1998-12-14 EP EP98963915A patent/EP1040111B1/en not_active Expired - Lifetime
- 1998-12-14 PT PT98963915T patent/PT1040111E/pt unknown
- 1998-12-14 KR KR1020007006653A patent/KR20010024748A/ko active IP Right Grant
- 1998-12-14 SI SI9830777T patent/SI1040111T1/xx unknown
- 1998-12-14 TR TR2000/01752T patent/TR200001752T2/xx unknown
- 1998-12-14 SK SK916-2000A patent/SK9162000A3/sk unknown
- 1998-12-14 EE EEP200000360A patent/EE200000360A/xx unknown
- 1998-12-14 HU HU0100178A patent/HUP0100178A3/hu unknown
- 1998-12-14 AU AU19144/99A patent/AU741769B2/en not_active Expired
- 1998-12-14 ES ES98963915T patent/ES2243016T3/es not_active Expired - Lifetime
- 1998-12-14 PL PL98341095A patent/PL341095A1/xx not_active Application Discontinuation
- 1998-12-14 DK DK98963915T patent/DK1040111T3/da active
- 1998-12-14 AT AT98963915T patent/ATE298338T1/de active
- 1998-12-14 NZ NZ504896A patent/NZ504896A/xx unknown
- 1998-12-14 CA CA002315189A patent/CA2315189C/en not_active Expired - Lifetime
- 1998-12-14 JP JP2000539023A patent/JP3589633B2/ja not_active Expired - Lifetime
- 1998-12-17 PE PE1998001244A patent/PE20000010A1/es not_active Application Discontinuation
-
2000
- 2000-05-26 IS IS5513A patent/IS5513A/is unknown
- 2000-06-16 NO NO20003113A patent/NO317975B1/no not_active IP Right Cessation
- 2000-07-13 BG BG104601A patent/BG104601A/bg unknown
-
2004
- 2004-06-24 JP JP2004185935A patent/JP2004300158A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ504896A (en) | 2002-10-25 |
PE20000010A1 (es) | 2000-01-29 |
ES2243016T3 (es) | 2005-11-16 |
CA2315189C (en) | 2005-04-19 |
SI1040111T1 (en) | 2005-10-31 |
AU1914499A (en) | 1999-07-05 |
HUP0100178A3 (en) | 2002-12-28 |
KR20030048081A (ko) | 2003-06-18 |
AU741769B2 (en) | 2001-12-06 |
DK1040111T3 (da) | 2005-10-10 |
JP2004300158A (ja) | 2004-10-28 |
EP1040111A1 (en) | 2000-10-04 |
PL341095A1 (en) | 2001-03-26 |
PT1040111E (pt) | 2005-10-31 |
ATE298338T1 (de) | 2005-07-15 |
JP3589633B2 (ja) | 2004-11-17 |
KR20010024748A (ko) | 2001-03-26 |
EA200000653A1 (ru) | 2000-12-25 |
CA2315189A1 (en) | 1999-06-24 |
JP2002508374A (ja) | 2002-03-19 |
HUP0100178A2 (hu) | 2001-11-28 |
EA003095B1 (ru) | 2002-12-26 |
BG104601A (bg) | 2001-01-31 |
EP1040111B1 (en) | 2005-06-22 |
WO1999031099A1 (en) | 1999-06-24 |
SK9162000A3 (en) | 2001-03-12 |
EE200000360A (et) | 2001-12-17 |
NO20003113D0 (no) | 2000-06-16 |
NO20003113L (no) | 2000-08-16 |
IS5513A (is) | 2000-05-26 |
TR200001752T2 (tr) | 2000-12-21 |
NO317975B1 (no) | 2005-01-17 |
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