UA76934C2
(en)
*
|
1996-10-04 |
2006-10-16 |
Chugai Pharmaceutical Co Ltd |
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
|
BR9811094A
(pt)
*
|
1997-02-12 |
2000-07-18 |
Chugai Pharmaceutical Co Ltd |
Agente terapêutico para tumores linfáticos
|
WO1999043703A1
(fr)
*
|
1998-02-25 |
1999-09-02 |
Chugai Seiyaku Kabushiki Kaisha |
Technique de dosage immunochimique de l'anticorps anti-hm1.24
|
AU2001246846A1
(en)
*
|
2000-04-06 |
2001-10-23 |
Chugai Seiyaku Kabushiki Kaisha |
Immunoassay of anti-hm1.24 antibody
|
WO2002064159A1
(en)
|
2001-02-07 |
2002-08-22 |
Chugai Seiyaku Kabushiki Kaisha |
Remedies for tumor in hematopoietic organs
|
EP2336149A1
(en)
*
|
2001-03-09 |
2011-06-22 |
Chugai Seiyaku Kabushiki Kaisha |
Protein purification method
|
US20040236080A1
(en)
*
|
2001-06-22 |
2004-11-25 |
Hiroyuki Aburatani |
Cell proliferation inhibitors containing anti-glypican 3 antibody
|
US20080219974A1
(en)
*
|
2002-03-01 |
2008-09-11 |
Bernett Matthew J |
Optimized antibodies that target hm1.24
|
DE60327199D1
(de)
|
2002-04-26 |
2009-05-28 |
Chugai Pharmaceutical Co Ltd |
Verfahren zum screening auf agonistische antikörper
|
EP2898897A3
(en)
*
|
2004-07-09 |
2015-10-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-glypican 3 antibody
|
BRPI0518279A2
(pt)
*
|
2004-10-26 |
2008-11-11 |
Chugai Pharmaceutical Co Ltd |
anticorpo antiglipicam 3 tendo cadeia de aÇécar modificada
|
US20080299128A1
(en)
*
|
2006-06-20 |
2008-12-04 |
Myung Kim |
Effect of Bst2 on inflammation
|
US8329186B2
(en)
*
|
2004-12-20 |
2012-12-11 |
Isu Abxis Co., Ltd |
Treatment of inflammation using BST2 inhibitor
|
AU2006232287B2
(en)
|
2005-03-31 |
2011-10-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing polypeptides by regulating polypeptide association
|
US20070087005A1
(en)
*
|
2005-10-14 |
2007-04-19 |
Lazar Gregory A |
Anti-glypican-3 antibody
|
EP1973559B1
(en)
|
2005-11-23 |
2013-01-09 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for promoting bone growth
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
JP5624276B2
(ja)
|
2006-03-31 |
2014-11-12 |
中外製薬株式会社 |
抗体の血中動態を制御する方法
|
EP3345616A1
(en)
|
2006-03-31 |
2018-07-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
AU2007299843B2
(en)
|
2006-09-18 |
2012-03-08 |
Xencor, Inc |
Optimized antibodies that target HM1.24
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
TWI480048B
(zh)
|
2007-02-01 |
2015-04-11 |
Acceleron Pharma Inc |
活化素-ActRIIa拮抗劑及其治療或預防乳癌之用途
|
TW201627320A
(zh)
|
2007-02-02 |
2016-08-01 |
艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
TW201808334A
(zh)
|
2007-02-09 |
2018-03-16 |
艾瑟勒朗法瑪公司 |
包含ActRIIa-Fc融合蛋白的醫藥組合物;ActRIIa-Fc融合蛋白於治療或預防與癌症相關的骨質流失之用途;ActRIIa-Fc融合蛋白於治療或預防多發性骨髓瘤之用途
|
EP3392273A1
(en)
|
2007-05-30 |
2018-10-24 |
Xencor, Inc. |
Methods and compositions for inhibiting cd32b expressing cells
|
RU2557319C2
(ru)
|
2007-07-16 |
2015-07-20 |
Дженентек, Инк. |
ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ CD79b И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ПРИМЕНЕНИЯ
|
SG183023A1
(en)
|
2007-07-16 |
2012-08-30 |
Genentech Inc |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
EP2207562B1
(en)
|
2007-09-18 |
2017-05-31 |
Acceleron Pharma, Inc. |
Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
|
KR102225009B1
(ko)
|
2007-09-26 |
2021-03-08 |
추가이 세이야쿠 가부시키가이샤 |
항체 정상영역 개변체
|
JP5334319B2
(ja)
*
|
2007-09-26 |
2013-11-06 |
中外製薬株式会社 |
Cdrのアミノ酸置換により抗体の等電点を改変する方法
|
RU2010116756A
(ru)
|
2007-09-28 |
2011-11-10 |
Чугаи Сейяку Кабусики Кайся (Jp) |
Антитело против глипикана-3 с улучшенными кинетическими показателями в плазме
|
ES2450755T3
(es)
*
|
2007-10-19 |
2014-03-25 |
Genentech, Inc. |
Anticuerpos anti-TENB2 modificados por ingeniería genética con cisteína, y conjugados de anticuerpo y fármaco
|
BRPI0821110B8
(pt)
|
2007-12-05 |
2021-05-25 |
Chugai Pharmaceutical Co Ltd |
anticorpo de neutralização de anti-nr10/il31ra, composição farmacêutica compreendendo o referido anticorpo e uso do mesmo
|
WO2009099728A1
(en)
|
2008-01-31 |
2009-08-13 |
Genentech, Inc. |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
KR20220162801A
(ko)
|
2008-04-11 |
2022-12-08 |
추가이 세이야쿠 가부시키가이샤 |
복수 분자의 항원에 반복 결합하는 항원 결합 분자
|
TW201803586A
(zh)
|
2008-08-14 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
使用gdf阱以增加紅血球水平
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
TWI440469B
(zh)
*
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
EP2409990A4
(en)
|
2009-03-19 |
2013-01-23 |
Chugai Pharmaceutical Co Ltd |
VARIANT OF A CONSTANT ANTIBODY REGION
|
EP2409991B1
(en)
|
2009-03-19 |
2017-05-03 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
ES2836534T3
(es)
|
2009-06-12 |
2021-06-25 |
Acceleron Pharma Inc |
Proteínas de fusión de ActRIIB-Fc truncadas
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
ES2658292T3
(es)
|
2009-11-17 |
2018-03-09 |
Acceleron Pharma, Inc. |
Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
ES2547142T5
(es)
|
2010-02-08 |
2021-12-09 |
Regeneron Pharma |
Cadena ligera común de ratón
|
EP2543730B1
(en)
|
2010-03-04 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
CA2817008A1
(en)
|
2010-11-08 |
2012-05-18 |
Acceleron Pharma Inc. |
Actriia binding agents and uses thereof
|
TWI452136B
(zh)
|
2010-11-17 |
2014-09-11 |
中外製藥股份有限公司 |
A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation
|
EP2647706B1
(en)
|
2010-11-30 |
2023-05-17 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
EP2679681B2
(en)
|
2011-02-25 |
2023-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
FcgammaRIIB-specific FC antibody
|
PL3572517T3
(pl)
|
2011-08-05 |
2021-10-04 |
Regeneron Pharmaceuticals, Inc. |
Myszy z humanizowanym uniwersalnym łańcuchem lekkim
|
TW201817744A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
WO2013047748A1
(ja)
|
2011-09-30 |
2013-04-04 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
US8765385B2
(en)
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
US20140013456A1
(en)
|
2012-03-16 |
2014-01-09 |
Regeneron Pharmaceuticals, Inc. |
Histidine Engineered Light Chain Antibodies and Genetically Modified Non-Human Animals for Generating the Same
|
EP2883449B1
(en)
|
2012-03-16 |
2018-02-07 |
Regeneron Pharmaceuticals, Inc. |
Histidine engineered light chain antibodies and genetically modified rodents for generating the same
|
CN107361011B
(zh)
|
2012-03-16 |
2021-08-27 |
瑞泽恩制药公司 |
制备表达ph敏感性免疫球蛋白序列的非人动物的方法
|
KR20140134672A
(ko)
|
2012-03-16 |
2014-11-24 |
리제너론 파마슈티칼스 인코포레이티드 |
pH-의존성 결합 특성을 나타내는 항원-결합 단백질을 생성하는 마우스
|
CN104936605A
(zh)
|
2012-11-02 |
2015-09-23 |
细胞基因公司 |
激活素-actrii拮抗剂和用于治疗骨和其它病症的用途
|
WO2015046467A1
(ja)
|
2013-09-27 |
2015-04-02 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
KR20210088756A
(ko)
|
2014-03-21 |
2021-07-14 |
리제너론 파마슈티칼스 인코포레이티드 |
단일 도메인 결합 단백질을 생산하는 비-인간 동물
|
WO2015192111A1
(en)
|
2014-06-13 |
2015-12-17 |
Acceleron Pharma, Inc. |
Methods and compositions for treating ulcers
|
AU2015320678B2
(en)
|
2014-09-23 |
2021-07-22 |
Genentech, Inc. |
Method of using anti-CD79b immunoconjugates
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
KR20180054923A
(ko)
|
2014-12-19 |
2018-05-24 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
KR102515796B1
(ko)
|
2014-12-19 |
2023-03-30 |
추가이 세이야쿠 가부시키가이샤 |
항-c5 항체 및 그의 사용 방법
|
MX2017008978A
(es)
|
2015-02-05 |
2017-10-25 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos que comprenden un dominio de union al antigeno dependiente de la concentracion ionica, variantes de la region fc, antiocuerpor de union a interleucina 8 (il-8) y usos de los mismos.
|
EP4269440A3
(en)
|
2015-02-27 |
2024-02-28 |
Chugai Seiyaku Kabushiki Kaisha |
Composition for treating il-6-related diseases
|
CN107438622A
(zh)
|
2015-03-19 |
2017-12-05 |
瑞泽恩制药公司 |
选择结合抗原的轻链可变区的非人动物
|
JP7082484B2
(ja)
|
2015-04-01 |
2022-06-08 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
US11359009B2
(en)
|
2015-12-25 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
BR112018009312A8
(pt)
|
2015-12-28 |
2019-02-26 |
Chugai Pharmaceutical Co Ltd |
método para promover eficiência de purificação de polipeptídeo contendo região de fc
|
KR102457751B1
(ko)
|
2016-03-10 |
2022-10-21 |
악셀레론 파마 인코포레이티드 |
액티빈 타입 2 수용체 결합 단백질 및 이의 용도
|
RU2746754C2
(ru)
|
2016-03-14 |
2021-04-20 |
Чугаи Сейяку Кабусики Кайся |
Индуцирующее повреждение клеток терапевтическое лекарственное средство, предназначенное для противораковой терапии
|
HUE064454T2
(hu)
|
2016-06-08 |
2024-03-28 |
Xencor Inc |
IgG4-gyel kapcsolatos betegségek kezelése CD32B-vel keresztkötõ, CD-19 elleni ellenanyagokkal
|
CN107619443B
(zh)
*
|
2016-07-14 |
2020-08-14 |
深圳宾德生物技术有限公司 |
抗人和鼠cd317的单克隆抗体及其制备方法和应用
|
US11053308B2
(en)
|
2016-08-05 |
2021-07-06 |
Chugai Seiyaku Kabushiki Kaisha |
Method for treating IL-8-related diseases
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|