IL134372A0 - Recombinant expression of insulin c-peptide - Google Patents

Recombinant expression of insulin c-peptide

Info

Publication number
IL134372A0
IL134372A0 IL13437298A IL13437298A IL134372A0 IL 134372 A0 IL134372 A0 IL 134372A0 IL 13437298 A IL13437298 A IL 13437298A IL 13437298 A IL13437298 A IL 13437298A IL 134372 A0 IL134372 A0 IL 134372A0
Authority
IL
Israel
Prior art keywords
insulin
peptide
recombinant expression
recombinant
expression
Prior art date
Application number
IL13437298A
Other languages
English (en)
Original Assignee
Creative Peptides Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creative Peptides Sweden Ab filed Critical Creative Peptides Sweden Ab
Publication of IL134372A0 publication Critical patent/IL134372A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL13437298A 1997-08-07 1998-08-07 Recombinant expression of insulin c-peptide IL134372A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9716790.2A GB9716790D0 (en) 1997-08-07 1997-08-07 Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof
PCT/GB1998/002382 WO1999007735A2 (en) 1997-08-07 1998-08-07 Recombinant expression of insulin c-peptide

Publications (1)

Publication Number Publication Date
IL134372A0 true IL134372A0 (en) 2001-04-30

Family

ID=10817184

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13437298A IL134372A0 (en) 1997-08-07 1998-08-07 Recombinant expression of insulin c-peptide

Country Status (21)

Country Link
US (1) US6558924B1 (xx)
EP (1) EP1001980A1 (xx)
JP (1) JP2001512745A (xx)
KR (1) KR20010022590A (xx)
CN (1) CN1268141A (xx)
AU (1) AU750685B2 (xx)
BG (1) BG104161A (xx)
BR (1) BR9811850A (xx)
CA (1) CA2297382A1 (xx)
EA (1) EA200000202A1 (xx)
EE (1) EE200000072A (xx)
GB (1) GB9716790D0 (xx)
HU (1) HUP0004626A1 (xx)
IL (1) IL134372A0 (xx)
IS (1) IS5368A (xx)
NO (1) NO20000575L (xx)
NZ (1) NZ502450A (xx)
PL (1) PL339085A1 (xx)
SK (1) SK1532000A3 (xx)
TR (1) TR200000288T2 (xx)
WO (1) WO1999007735A2 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005669A1 (en) * 1997-08-07 2004-01-08 Stefan Stahl Recombinant expression of insulin C-peptide
FR2810675B1 (fr) * 2000-06-22 2002-09-27 Pf Medicament Construction modifiee en aval du codon d'initiation pour la surexpression de proteines recombinantes
FR2810674A1 (fr) * 2000-06-22 2001-12-28 Pf Medicament Construction modifiee en amont du codon d'initiation pour la surexpression de proteines recombinantes
AU2002233230B2 (en) * 2000-12-20 2007-02-01 F. Hoffmann-La Roche Ag Erythropoietin conjugates
CN101044154A (zh) * 2002-02-14 2007-09-26 威廉·J·鲁特 治疗宿主中切割的嵌合分子
SG159387A1 (en) 2002-11-26 2010-03-30 Biocon Ltd In Modified natriuretic compounds, conjugates, and uses thereof
US20050026826A1 (en) * 2003-01-17 2005-02-03 Margarethe Hoenig Feline proinsulin, insulin and constituent peptides
US7795384B2 (en) * 2003-06-03 2010-09-14 Shanghai Centre Of Research & Development Of New Drugs Fusion protein suitable for high efficiency expression and the production method thereof
KR20070033965A (ko) * 2004-03-10 2007-03-27 크레이톤 유니버시티 에스트로젠 수용체 및 사용 방법
CN103119055A (zh) 2010-05-17 2013-05-22 塞比克斯公司 聚乙二醇化c肽
CA2855770A1 (en) 2011-11-17 2013-05-23 Cebix Ab Pegylated c-peptide
EP2839010B1 (en) * 2012-03-19 2018-04-25 Madeleine Pharmaceuticals Pty Ltd Method of producing a recombinant peptide
US10627415B2 (en) 2015-03-12 2020-04-21 Board Of Trustees Of Michigan State University Compositions and methods for diagnosing, monitoring, and treating an autoimmune disease
CN109705221B (zh) * 2018-12-27 2021-03-09 美康生物科技股份有限公司 C肽免疫原及其单克隆抗体对及该抗体对在c肽磁微粒化学发光免疫试剂中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5210872B2 (xx) 1973-07-14 1977-03-26
GB2068971B (en) 1980-01-30 1983-06-08 Searle & Co Recombinant dna techniques
CA1213537A (en) 1984-05-01 1986-11-04 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Polypeptide expression method
DE3852074D1 (de) 1987-03-20 1994-12-15 Creative Biomolecules Inc Verfahren zur reinigung von rekombinanten polypeptiden.
US5013653A (en) 1987-03-20 1991-05-07 Creative Biomolecules, Inc. Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
SE501169C2 (sv) 1988-02-05 1994-11-28 Aake Nygren Framställning av serumalbuminbindande fusionsproteiner vilka innehåller protein G-domäner
US5130236A (en) 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
US5595887A (en) 1990-07-16 1997-01-21 Bionebraska, Inc. Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
GB9015825D0 (en) 1990-07-18 1990-09-05 Ciba Geigy Ag In vitro processing of fusion proteins
JPH07108232B2 (ja) 1990-10-09 1995-11-22 エム・ディ・リサーチ株式会社 ペプチド又は蛋白質の製造方法
US5953418A (en) 1995-06-14 1999-09-14 David Hall Providing selective data broadcast receiver addressability
CA2213512A1 (en) 1995-12-22 1997-07-03 Toray Industries, Inc. Method for producing bioactive fusion protein

Also Published As

Publication number Publication date
AU8640798A (en) 1999-03-01
WO1999007735A3 (en) 1999-04-29
CA2297382A1 (en) 1999-02-18
BG104161A (en) 2000-12-29
US6558924B1 (en) 2003-05-06
WO1999007735A2 (en) 1999-02-18
NO20000575L (no) 2000-04-04
EA200000202A1 (ru) 2001-04-23
GB9716790D0 (en) 1997-10-15
PL339085A1 (en) 2000-12-04
KR20010022590A (ko) 2001-03-26
EE200000072A (et) 2000-10-16
HUP0004626A1 (hu) 2001-04-28
NZ502450A (en) 2002-10-25
JP2001512745A (ja) 2001-08-28
EP1001980A1 (en) 2000-05-24
TR200000288T2 (tr) 2000-06-21
BR9811850A (pt) 2000-08-08
IS5368A (is) 2000-02-01
AU750685B2 (en) 2002-07-25
CN1268141A (zh) 2000-09-27
SK1532000A3 (en) 2000-09-12
NO20000575D0 (no) 2000-02-04

Similar Documents

Publication Publication Date Title
PL337324A1 (en) Stable insulin preparations
EP1039920A4 (en) INSULIN ANALOGS ACYLATED BY FATTY ACID
ZA985363B (en) Novel insulin derivatives having a rapid onset of action
HUP0002127A3 (en) Syringe
EP0979660A4 (en) SYRINGE
HUP0202755A3 (en) C-peptide for the improved production of insulin and insulin analogues
AU1306799A (en) Improved injector syringe
HUP9904596A3 (en) Analogs of parathyroid hormone
EP0688570A3 (de) Insulinspritze
HUP9904031A3 (en) Insulin preparations containing nacl
IL134372A0 (en) Recombinant expression of insulin c-peptide
AU3236895A (en) Aspb1 insulin analogs
HUP0000432A3 (en) Insulin c-peptides
AU6586298A (en) Glucagon-like peptide-1 analogs
PL310007A1 (en) Insulin analogues
IL132454A0 (en) Calcitonin receptor-binding peptides
SI0884053T1 (en) Stable insulin formulations
ZA98607B (en) Pulsatile delivery of diltiazem-HC1
GB9714680D0 (en) Recombinant production of proteins
AU2940895A (en) Use of insulin and igf-i
GB9513967D0 (en) Insulin
GB9700789D0 (en) Syringe
TW364360U (en) Improvement on structure of syringe
GB9727105D0 (en) Hypodermic syringe
ZA975495B (en) Production of recombinant baculoviruses