IL129868A - Process for the synthesis of benzotiopes - Google Patents

Process for the synthesis of benzotiopes

Info

Publication number
IL129868A
IL129868A IL12986897A IL12986897A IL129868A IL 129868 A IL129868 A IL 129868A IL 12986897 A IL12986897 A IL 12986897A IL 12986897 A IL12986897 A IL 12986897A IL 129868 A IL129868 A IL 129868A
Authority
IL
Israel
Prior art keywords
compound
reaction
formula
process according
solvent
Prior art date
Application number
IL12986897A
Other languages
English (en)
Hebrew (he)
Other versions
IL129868A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to IL14495397A priority Critical patent/IL144953A0/xx
Publication of IL129868A0 publication Critical patent/IL129868A0/xx
Publication of IL129868A publication Critical patent/IL129868A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL12986897A 1996-11-19 1997-11-14 Process for the synthesis of benzotiopes IL129868A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL14495397A IL144953A0 (en) 1996-11-19 1997-11-14 Process for the synthesis of benzothiophenes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3118196P 1996-11-19 1996-11-19
PCT/US1997/021820 WO1998022456A1 (en) 1996-11-19 1997-11-14 Process for the synthesis of benzothiophenes

Publications (2)

Publication Number Publication Date
IL129868A0 IL129868A0 (en) 2000-02-29
IL129868A true IL129868A (en) 2002-09-12

Family

ID=21858059

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12986897A IL129868A (en) 1996-11-19 1997-11-14 Process for the synthesis of benzotiopes

Country Status (23)

Country Link
US (1) US5969157A (es)
EP (1) EP0842930B1 (es)
JP (1) JP2001504497A (es)
KR (1) KR20000053333A (es)
CN (1) CN1130357C (es)
AR (1) AR010615A1 (es)
AT (1) ATE217620T1 (es)
AU (1) AU726401B2 (es)
BR (1) BR9712773A (es)
CA (1) CA2271922A1 (es)
CO (1) CO4920247A1 (es)
DE (1) DE69712590T2 (es)
DK (1) DK0842930T3 (es)
ES (1) ES2173399T3 (es)
HU (1) HUP9904510A3 (es)
ID (1) ID18917A (es)
IL (1) IL129868A (es)
PE (1) PE16799A1 (es)
PT (1) PT842930E (es)
SI (1) SI0842930T1 (es)
TW (1) TW461888B (es)
WO (1) WO1998022456A1 (es)
ZA (1) ZA9710262B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6335600A (en) * 1999-07-29 2001-02-19 Eli Lilly And Company A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride
US6921827B2 (en) * 2000-11-27 2005-07-26 Eli Lilly And Company Process for preparing 3-aryl-benzo{b} thiophenes
US20050069962A1 (en) 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
US8323903B2 (en) 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
JP4589106B2 (ja) * 2002-05-31 2010-12-01 ジェネティック テクノロジーズ リミテッド 母体血由来の胎児細胞を同定し濃化するための胎児細胞マーカーとしての母体抗体
CA2499819A1 (en) 2002-09-30 2004-04-08 A/S Gea Farmaceutisk Fabrik Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
KR20090082399A (ko) 2006-10-17 2009-07-30 씨아이피엘에이 엘티디. 벤조티오펜 화합물의 결정형 및 그의 제조방법
SG175282A1 (en) 2009-04-21 2011-11-28 Genetic Technologies Ltd Methods for obtaining fetal genetic material

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
AU509682B2 (en) * 1975-10-28 1980-05-22 Eli Lilly And Company 2-Aroyl-3-Phenylbenzothiophene Derivatives
AT364852B (de) * 1977-11-05 1981-11-25 Thomae Gmbh Dr K Verfahren zur herstellung von kondensierten isothiazol-3(2h)-on-1,1-dioxiden und von deren salzen
US4436748A (en) * 1980-10-20 1984-03-13 Hoechst-Roussel Pharmaceuticals Inc. Benzo[b]thiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
IL65378A (en) * 1981-04-03 1986-02-28 Lilly Co Eli Process for preparing 3-(4-aminoethoxybenzoyl)benzo-(b)thiophenes
US4544746A (en) * 1982-05-17 1985-10-01 Ciba-Geigy Corporation Process for preparing 2-anilinoacridone
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
DE4204969A1 (de) * 1992-02-19 1993-08-26 Basf Ag Verfahren zur herstellung von benzo(b)thiophenen
US5466810A (en) * 1994-06-10 1995-11-14 Eli Lilly And Company 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[β]thiophenes
DE4423893C2 (de) * 1994-07-07 1996-09-05 Freudenberg Carl Fa Flachdichtung mit flexibler Leiterplatte
US5523416A (en) * 1994-07-22 1996-06-04 Eli Lilly And Company Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes
US5552401A (en) * 1995-02-28 1996-09-03 Eli Lilly And Company 2-benzyl-3-arylbenzothiophenes
US5614639A (en) * 1995-03-31 1997-03-25 Eli Lilly And Company Process for preparing 2-substituted benzo[b]thiophene compounds and intermediates thereof
US5606075A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
US5606076A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes

Also Published As

Publication number Publication date
AR010615A1 (es) 2000-06-28
DK0842930T3 (da) 2002-07-15
PE16799A1 (es) 1999-02-19
HUP9904510A2 (hu) 2000-05-28
AU726401B2 (en) 2000-11-09
ZA9710262B (en) 1999-05-13
TW461888B (en) 2001-11-01
WO1998022456A1 (en) 1998-05-28
CN1237968A (zh) 1999-12-08
ATE217620T1 (de) 2002-06-15
ID18917A (id) 1998-05-20
BR9712773A (pt) 1999-10-26
PT842930E (pt) 2002-08-30
HUP9904510A3 (en) 2000-08-28
CN1130357C (zh) 2003-12-10
EP0842930A1 (en) 1998-05-20
CO4920247A1 (es) 2000-05-29
CA2271922A1 (en) 1998-05-28
EP0842930B1 (en) 2002-05-15
JP2001504497A (ja) 2001-04-03
SI0842930T1 (en) 2002-10-31
DE69712590D1 (de) 2002-06-20
ES2173399T3 (es) 2002-10-16
IL129868A0 (en) 2000-02-29
DE69712590T2 (de) 2002-10-31
US5969157A (en) 1999-10-19
AU5462298A (en) 1998-06-10
KR20000053333A (ko) 2000-08-25

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees