IL127408A - תולדות 2, 4 - תיאזולידינדיון, תהליך להכנתן ותכשירי רוקחות המכילים אותן - Google Patents
תולדות 2, 4 - תיאזולידינדיון, תהליך להכנתן ותכשירי רוקחות המכילים אותןInfo
- Publication number
- IL127408A IL127408A IL12740897A IL12740897A IL127408A IL 127408 A IL127408 A IL 127408A IL 12740897 A IL12740897 A IL 12740897A IL 12740897 A IL12740897 A IL 12740897A IL 127408 A IL127408 A IL 127408A
- Authority
- IL
- Israel
- Prior art keywords
- general formula
- group
- thiazolidinedione
- compound
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9607070A FR2749583B1 (fr) | 1996-06-07 | 1996-06-07 | Nouveaux derives de thiazolidine -2,4- dione substitues, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant |
PCT/EP1997/002851 WO1997047612A1 (fr) | 1996-06-07 | 1997-06-02 | Nouveaux derives de thiazolidine-2,4-dione substitues, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant |
Publications (2)
Publication Number | Publication Date |
---|---|
IL127408A0 IL127408A0 (en) | 1999-10-28 |
IL127408A true IL127408A (he) | 2002-08-14 |
Family
ID=9492815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12740897A IL127408A (he) | 1996-06-07 | 1997-06-02 | תולדות 2, 4 - תיאזולידינדיון, תהליך להכנתן ותכשירי רוקחות המכילים אותן |
Country Status (31)
Country | Link |
---|---|
US (2) | US6437143B2 (he) |
EP (1) | EP0918759B1 (he) |
JP (2) | JP3067809B2 (he) |
KR (1) | KR20000016412A (he) |
CN (2) | CN1075811C (he) |
AR (1) | AR008387A1 (he) |
AT (1) | ATE222897T1 (he) |
AU (1) | AU726549B2 (he) |
BR (1) | BR9709654A (he) |
CA (1) | CA2257275A1 (he) |
CZ (1) | CZ397598A3 (he) |
DE (1) | DE69715009T2 (he) |
DK (1) | DK0918759T3 (he) |
EE (1) | EE04015B1 (he) |
ES (1) | ES2180995T3 (he) |
FR (1) | FR2749583B1 (he) |
HK (1) | HK1019601A1 (he) |
HU (1) | HUP0001744A3 (he) |
ID (1) | ID17810A (he) |
IL (1) | IL127408A (he) |
NO (1) | NO312100B1 (he) |
NZ (1) | NZ333645A (he) |
PL (1) | PL330363A1 (he) |
PT (1) | PT918759E (he) |
RU (1) | RU2169144C2 (he) |
SK (1) | SK164598A3 (he) |
TR (1) | TR199802518T2 (he) |
TW (1) | TW400330B (he) |
UA (1) | UA57024C2 (he) |
WO (1) | WO1997047612A1 (he) |
ZA (1) | ZA974984B (he) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6083966A (en) * | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
EP1143951A3 (en) * | 1998-09-21 | 2002-02-06 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
KR20010112328A (ko) * | 1999-03-18 | 2001-12-20 | 우에노 도시오 | 티아졸리딘 유도체의 제조 방법 |
US6417212B1 (en) | 1999-08-27 | 2002-07-09 | Eli Lilly & Company | Modulators of peroxisome proliferator activated receptors |
FR2812547B1 (fr) * | 2000-08-04 | 2002-10-31 | Lipha | Composition pharmaceutique comprenant une association metformine et derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete |
FR2822069B1 (fr) * | 2001-03-19 | 2003-06-20 | Lipha | Composition pharmaceutique comprenant un compose stimulant la secretion d'insuline et un derive de thiazolidinedione et son utilisation pour la preparation de medicamments destines a traiter le diabete |
FR2826278B1 (fr) * | 2001-06-20 | 2005-03-25 | Lipha | Utilisation d'agents antidiabetiques pour fabriquer un medicament ayant un effet cicatrisant |
JP2005528322A (ja) | 2001-09-26 | 2005-09-22 | エミスフェアー・テクノロジーズ・インク | ジカルボキシラート中間体を経てフェノキシアルカン酸、アルケン酸およびアルキン酸ならびにそれらの塩を調製する方法 |
FR2838968A1 (fr) * | 2002-04-30 | 2003-10-31 | Lipha | Association d'insuline et d'un derive de thiazolidinedione et son utilisation pour traiter le diabete |
FR2845003A1 (fr) * | 2002-09-30 | 2004-04-02 | Merck Sante Sas | Utilisation de derives de thiazolidinedione comme inhibiteurs de l'aldose reductase |
WO2005034949A1 (en) * | 2003-09-09 | 2005-04-21 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
US20060263453A1 (en) * | 2004-11-01 | 2006-11-23 | Thomas Smith | Methods and compositions for modulating glutamate dehydrogenase |
TR201910900T4 (tr) | 2005-04-04 | 2019-08-21 | Univ Florida | Desferritiyokin polieter analogları. |
NZ579994A (en) | 2007-03-15 | 2011-09-30 | Univ Florida | Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal |
US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
US20160331729A9 (en) | 2007-04-11 | 2016-11-17 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
AU2008240158B2 (en) * | 2007-04-11 | 2014-07-10 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
DE102007028925A1 (de) * | 2007-06-22 | 2008-12-24 | Saltigo Gmbh | Verfahren zur Herstellung von 2-Phenoxyacetalen und den daraus korrespondierenden 2-Phenoxycarbaldehyden |
MX368275B (es) | 2011-12-16 | 2019-09-26 | Univ Florida | Usos de análogos de 4'-desferritiocina. |
WO2015042495A2 (en) * | 2013-09-22 | 2015-03-26 | Jiva Pharma, Inc. | Metformin salts to treat type2 diabetes |
JP6838966B2 (ja) | 2013-11-22 | 2021-03-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | デスフェリチオシン類似体およびその使用 |
KR20170140306A (ko) | 2015-04-27 | 2017-12-20 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 대사적으로 프로그램화된 금속 킬레이트화제 및 그의 용도 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
TW268952B (he) * | 1993-02-26 | 1996-01-21 | Takeda Pharm Industry Co Ltd | |
US5614544A (en) * | 1993-09-14 | 1997-03-25 | Takeda Chemical Industries, Ltd. | Oxazolidinedione derivatives and their use |
EP0783496B9 (en) * | 1994-08-10 | 2003-09-03 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, their production and use |
-
1996
- 1996-06-07 FR FR9607070A patent/FR2749583B1/fr not_active Expired - Fee Related
-
1997
- 1997-02-06 UA UA99010018A patent/UA57024C2/uk unknown
- 1997-06-02 CN CN97195320A patent/CN1075811C/zh not_active Expired - Fee Related
- 1997-06-02 AT AT97925034T patent/ATE222897T1/de not_active IP Right Cessation
- 1997-06-02 DK DK97925034T patent/DK0918759T3/da active
- 1997-06-02 PL PL97330363A patent/PL330363A1/xx unknown
- 1997-06-02 RU RU99100100/04A patent/RU2169144C2/ru not_active IP Right Cessation
- 1997-06-02 CA CA002257275A patent/CA2257275A1/en not_active Abandoned
- 1997-06-02 TR TR1998/02518T patent/TR199802518T2/xx unknown
- 1997-06-02 CZ CZ983975A patent/CZ397598A3/cs unknown
- 1997-06-02 DE DE69715009T patent/DE69715009T2/de not_active Expired - Fee Related
- 1997-06-02 EP EP97925034A patent/EP0918759B1/fr not_active Expired - Lifetime
- 1997-06-02 EE EE9800426A patent/EE04015B1/xx not_active IP Right Cessation
- 1997-06-02 HU HU0001744A patent/HUP0001744A3/hu unknown
- 1997-06-02 PT PT97925034T patent/PT918759E/pt unknown
- 1997-06-02 AU AU30317/97A patent/AU726549B2/en not_active Ceased
- 1997-06-02 WO PCT/EP1997/002851 patent/WO1997047612A1/fr active Search and Examination
- 1997-06-02 KR KR1019980709995A patent/KR20000016412A/ko not_active Application Discontinuation
- 1997-06-02 US US09/202,076 patent/US6437143B2/en not_active Expired - Fee Related
- 1997-06-02 NZ NZ333645A patent/NZ333645A/xx unknown
- 1997-06-02 JP JP10501140A patent/JP3067809B2/ja not_active Expired - Fee Related
- 1997-06-02 BR BR9709654A patent/BR9709654A/pt not_active IP Right Cessation
- 1997-06-02 IL IL12740897A patent/IL127408A/he not_active IP Right Cessation
- 1997-06-02 SK SK1645-98A patent/SK164598A3/sk unknown
- 1997-06-02 ES ES97925034T patent/ES2180995T3/es not_active Expired - Lifetime
- 1997-06-05 ZA ZA9704984A patent/ZA974984B/xx unknown
- 1997-06-06 TW TW086107848A patent/TW400330B/zh active
- 1997-06-06 AR ARP970102468A patent/AR008387A1/es not_active Application Discontinuation
- 1997-06-09 ID IDP971967A patent/ID17810A/id unknown
-
1998
- 1998-12-04 NO NO19985671A patent/NO312100B1/no not_active IP Right Cessation
-
1999
- 1999-10-27 HK HK99104792A patent/HK1019601A1/xx not_active IP Right Cessation
- 1999-12-15 JP JP11355996A patent/JP2000226379A/ja active Pending
-
2001
- 2001-01-22 CN CN01103050A patent/CN1341588A/zh active Pending
-
2002
- 2002-06-27 US US10/180,071 patent/US20030100587A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |