IL126955A - Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising them - Google Patents
Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising themInfo
- Publication number
- IL126955A IL126955A IL12695598A IL12695598A IL126955A IL 126955 A IL126955 A IL 126955A IL 12695598 A IL12695598 A IL 12695598A IL 12695598 A IL12695598 A IL 12695598A IL 126955 A IL126955 A IL 126955A
- Authority
- IL
- Israel
- Prior art keywords
- hydrogen
- carbon atoms
- methyl
- group
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19749453A DE19749453A1 (de) | 1997-11-10 | 1997-11-10 | Sulfonamid-substituierte anellierte 5-Ring-Verbindungen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
Publications (2)
Publication Number | Publication Date |
---|---|
IL126955A0 IL126955A0 (en) | 1999-09-22 |
IL126955A true IL126955A (en) | 2002-11-10 |
Family
ID=7848065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12695598A IL126955A (en) | 1997-11-10 | 1998-11-08 | Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising them |
Country Status (29)
Country | Link |
---|---|
US (1) | US6015822A (ru) |
EP (1) | EP0915087B1 (ru) |
JP (1) | JP4331809B2 (ru) |
KR (1) | KR19990045147A (ru) |
CN (1) | CN1219533A (ru) |
AR (1) | AR016006A1 (ru) |
AT (1) | ATE236120T1 (ru) |
AU (1) | AU742199B2 (ru) |
BR (1) | BR9804995A (ru) |
CA (1) | CA2253211C (ru) |
CZ (1) | CZ363798A3 (ru) |
DE (2) | DE19749453A1 (ru) |
DK (1) | DK0915087T3 (ru) |
ES (1) | ES2196456T3 (ru) |
HR (1) | HRP980585B1 (ru) |
HU (1) | HUP9802590A3 (ru) |
ID (1) | ID21282A (ru) |
IL (1) | IL126955A (ru) |
MY (1) | MY115619A (ru) |
NO (1) | NO312546B1 (ru) |
NZ (1) | NZ332633A (ru) |
PL (1) | PL329596A1 (ru) |
PT (1) | PT915087E (ru) |
RU (1) | RU2223951C2 (ru) |
SI (1) | SI0915087T1 (ru) |
SK (1) | SK283866B6 (ru) |
TR (1) | TR199802270A2 (ru) |
TW (1) | TW427970B (ru) |
ZA (1) | ZA9810202B (ru) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1332943C (zh) | 1998-07-08 | 2007-08-22 | 萨诺费-阿文蒂斯德国有限公司 | 硫取代的磺酰基氨基羧酸n-芳基酰胺,其制备方法、用途以及含有该化合物的药物制剂 |
DE19929076A1 (de) * | 1999-06-25 | 2000-12-28 | Aventis Pharma Gmbh | Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
EP1240147A1 (en) | 1999-12-21 | 2002-09-18 | Icagen, Inc. | Potassium channel inhibitors |
US6849634B2 (en) | 2000-12-21 | 2005-02-01 | Icagen | Potassium channel inhibitors |
WO2003053954A1 (en) * | 2001-12-12 | 2003-07-03 | F. Hoffmann-La Roche Ag | Benzothiophenes as adenosine receptor modulators |
US7119112B2 (en) * | 2002-02-28 | 2006-10-10 | Icagen, Inc. | Sulfonamides as potassium channel blockers |
KR101126895B1 (ko) * | 2006-01-24 | 2012-03-20 | 일라이 릴리 앤드 캄파니 | 프로게스테론 수용체의 인돌 술폰아미드 조절제 |
JP2009026126A (ja) * | 2007-07-20 | 2009-02-05 | Nec Electronics Corp | 半導体装置 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR910003337B1 (ko) * | 1983-03-04 | 1991-05-27 | 오오쓰까세이야꾸 가부시끼가이샤 | 인단 유도체 및 그 염의 제조방법 |
DE3623944A1 (de) * | 1986-07-16 | 1988-02-11 | Thomae Gmbh Dr K | Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE3737195A1 (de) * | 1987-11-03 | 1989-05-18 | Bayer Ag | Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
FR2639349B1 (fr) * | 1988-11-23 | 1991-02-22 | Sanofi Sa | Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant |
US5104890A (en) * | 1989-03-28 | 1992-04-14 | Fujisawa Pharmaceutical Company, Ltd. | Benzopyran derivatives and processes for preparation thereof |
US5877218A (en) * | 1994-01-10 | 1999-03-02 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
-
1997
- 1997-11-10 DE DE19749453A patent/DE19749453A1/de not_active Withdrawn
-
1998
- 1998-11-04 PT PT98120913T patent/PT915087E/pt unknown
- 1998-11-04 AT AT98120913T patent/ATE236120T1/de not_active IP Right Cessation
- 1998-11-04 EP EP98120913A patent/EP0915087B1/de not_active Expired - Lifetime
- 1998-11-04 DE DE59807718T patent/DE59807718D1/de not_active Expired - Lifetime
- 1998-11-04 DK DK98120913T patent/DK0915087T3/da active
- 1998-11-04 ES ES98120913T patent/ES2196456T3/es not_active Expired - Lifetime
- 1998-11-04 SI SI9830428T patent/SI0915087T1/xx unknown
- 1998-11-05 NO NO19985171A patent/NO312546B1/no unknown
- 1998-11-06 AR ARP980105628A patent/AR016006A1/es not_active Application Discontinuation
- 1998-11-06 ID IDP981460A patent/ID21282A/id unknown
- 1998-11-06 RU RU98120643/04A patent/RU2223951C2/ru not_active IP Right Cessation
- 1998-11-06 AU AU91398/98A patent/AU742199B2/en not_active Ceased
- 1998-11-06 NZ NZ332633A patent/NZ332633A/xx unknown
- 1998-11-06 TW TW087118463A patent/TW427970B/zh active
- 1998-11-08 IL IL12695598A patent/IL126955A/en active IP Right Grant
- 1998-11-09 SK SK1545-98A patent/SK283866B6/sk unknown
- 1998-11-09 PL PL98329596A patent/PL329596A1/xx unknown
- 1998-11-09 US US09/188,181 patent/US6015822A/en not_active Expired - Lifetime
- 1998-11-09 TR TR1998/02270A patent/TR199802270A2/xx unknown
- 1998-11-09 JP JP31779998A patent/JP4331809B2/ja not_active Expired - Fee Related
- 1998-11-09 ZA ZA9810202A patent/ZA9810202B/xx unknown
- 1998-11-09 HU HU9802590A patent/HUP9802590A3/hu unknown
- 1998-11-09 HR HR980585A patent/HRP980585B1/xx not_active IP Right Cessation
- 1998-11-09 CZ CZ983637A patent/CZ363798A3/cs unknown
- 1998-11-10 CA CA002253211A patent/CA2253211C/en not_active Expired - Fee Related
- 1998-11-10 KR KR1019980047928A patent/KR19990045147A/ko not_active Application Discontinuation
- 1998-11-10 CN CN98124145A patent/CN1219533A/zh active Pending
- 1998-11-10 BR BR9804995-0A patent/BR9804995A/pt not_active IP Right Cessation
- 1998-11-10 MY MYPI98005112A patent/MY115619A/en unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed |