IL126955A - Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising them - Google Patents

Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising them

Info

Publication number
IL126955A
IL126955A IL12695598A IL12695598A IL126955A IL 126955 A IL126955 A IL 126955A IL 12695598 A IL12695598 A IL 12695598A IL 12695598 A IL12695598 A IL 12695598A IL 126955 A IL126955 A IL 126955A
Authority
IL
Israel
Prior art keywords
hydrogen
carbon atoms
methyl
group
alkyl
Prior art date
Application number
IL12695598A
Other languages
English (en)
Other versions
IL126955A0 (en
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of IL126955A0 publication Critical patent/IL126955A0/xx
Publication of IL126955A publication Critical patent/IL126955A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/07Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12695598A 1997-11-10 1998-11-08 Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising them IL126955A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19749453A DE19749453A1 (de) 1997-11-10 1997-11-10 Sulfonamid-substituierte anellierte 5-Ring-Verbindungen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
IL126955A0 IL126955A0 (en) 1999-09-22
IL126955A true IL126955A (en) 2002-11-10

Family

ID=7848065

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12695598A IL126955A (en) 1997-11-10 1998-11-08 Sulfonamide-substituted fused 5-membered ring compounds and pharmaceutical preparations comprising them

Country Status (29)

Country Link
US (1) US6015822A (ru)
EP (1) EP0915087B1 (ru)
JP (1) JP4331809B2 (ru)
KR (1) KR19990045147A (ru)
CN (1) CN1219533A (ru)
AR (1) AR016006A1 (ru)
AT (1) ATE236120T1 (ru)
AU (1) AU742199B2 (ru)
BR (1) BR9804995A (ru)
CA (1) CA2253211C (ru)
CZ (1) CZ363798A3 (ru)
DE (2) DE19749453A1 (ru)
DK (1) DK0915087T3 (ru)
ES (1) ES2196456T3 (ru)
HR (1) HRP980585B1 (ru)
HU (1) HUP9802590A3 (ru)
ID (1) ID21282A (ru)
IL (1) IL126955A (ru)
MY (1) MY115619A (ru)
NO (1) NO312546B1 (ru)
NZ (1) NZ332633A (ru)
PL (1) PL329596A1 (ru)
PT (1) PT915087E (ru)
RU (1) RU2223951C2 (ru)
SI (1) SI0915087T1 (ru)
SK (1) SK283866B6 (ru)
TR (1) TR199802270A2 (ru)
TW (1) TW427970B (ru)
ZA (1) ZA9810202B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332943C (zh) 1998-07-08 2007-08-22 萨诺费-阿文蒂斯德国有限公司 硫取代的磺酰基氨基羧酸n-芳基酰胺,其制备方法、用途以及含有该化合物的药物制剂
DE19929076A1 (de) * 1999-06-25 2000-12-28 Aventis Pharma Gmbh Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
EP1240147A1 (en) 1999-12-21 2002-09-18 Icagen, Inc. Potassium channel inhibitors
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors
WO2003053954A1 (en) * 2001-12-12 2003-07-03 F. Hoffmann-La Roche Ag Benzothiophenes as adenosine receptor modulators
US7119112B2 (en) * 2002-02-28 2006-10-10 Icagen, Inc. Sulfonamides as potassium channel blockers
KR101126895B1 (ko) * 2006-01-24 2012-03-20 일라이 릴리 앤드 캄파니 프로게스테론 수용체의 인돌 술폰아미드 조절제
JP2009026126A (ja) * 2007-07-20 2009-02-05 Nec Electronics Corp 半導体装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910003337B1 (ko) * 1983-03-04 1991-05-27 오오쓰까세이야꾸 가부시끼가이샤 인단 유도체 및 그 염의 제조방법
DE3623944A1 (de) * 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives

Also Published As

Publication number Publication date
JPH11236368A (ja) 1999-08-31
DE59807718D1 (de) 2003-05-08
DE19749453A1 (de) 1999-05-12
NO985171L (no) 1999-05-11
CZ363798A3 (cs) 1999-05-12
RU2223951C2 (ru) 2004-02-20
EP0915087A2 (de) 1999-05-12
HRP980585A2 (en) 1999-06-30
PT915087E (pt) 2003-08-29
TR199802270A2 (xx) 1999-05-21
EP0915087B1 (de) 2003-04-02
HU9802590D0 (en) 1999-01-28
JP4331809B2 (ja) 2009-09-16
EP0915087A3 (de) 1999-07-21
ATE236120T1 (de) 2003-04-15
CA2253211A1 (en) 1999-05-10
DK0915087T3 (da) 2003-07-21
SI0915087T1 (en) 2003-10-31
HUP9802590A3 (en) 2001-08-28
NO312546B1 (no) 2002-05-27
ZA9810202B (en) 1999-05-10
IL126955A0 (en) 1999-09-22
CA2253211C (en) 2009-04-14
SK154598A3 (en) 1999-06-11
AU742199B2 (en) 2001-12-20
US6015822A (en) 2000-01-18
SK283866B6 (sk) 2004-03-02
TW427970B (en) 2001-04-01
CN1219533A (zh) 1999-06-16
ES2196456T3 (es) 2003-12-16
HUP9802590A2 (hu) 2000-04-28
KR19990045147A (ko) 1999-06-25
ID21282A (id) 1999-05-12
PL329596A1 (en) 1999-05-24
AR016006A1 (es) 2001-05-30
AU9139898A (en) 1999-05-27
NZ332633A (en) 2000-05-26
NO985171D0 (no) 1998-11-05
HRP980585B1 (en) 2003-02-28
MY115619A (en) 2003-07-31
BR9804995A (pt) 2001-05-22

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Legal Events

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FF Patent granted
KB Patent renewed