ZA9810202B - Sulfonamide-substituted fused 5-membered ring compounds their use as a medicament and pharmaceutical preparations comprising them - Google Patents

Sulfonamide-substituted fused 5-membered ring compounds their use as a medicament and pharmaceutical preparations comprising them

Info

Publication number
ZA9810202B
ZA9810202B ZA9810202A ZA9810202A ZA9810202B ZA 9810202 B ZA9810202 B ZA 9810202B ZA 9810202 A ZA9810202 A ZA 9810202A ZA 9810202 A ZA9810202 A ZA 9810202A ZA 9810202 B ZA9810202 B ZA 9810202B
Authority
ZA
South Africa
Prior art keywords
sulfonamide
medicament
membered ring
pharmaceutical preparations
ring compounds
Prior art date
Application number
ZA9810202A
Other languages
English (en)
Inventor
Joachim Brendel
Uwe Gerlach
Hans Jochen Lang
Klaus Weidmann
Original Assignee
Hoechst Marion Roussel De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel De Gmbh filed Critical Hoechst Marion Roussel De Gmbh
Publication of ZA9810202B publication Critical patent/ZA9810202B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9810202A 1997-11-10 1998-11-09 Sulfonamide-substituted fused 5-membered ring compounds their use as a medicament and pharmaceutical preparations comprising them ZA9810202B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19749453A DE19749453A1 (de) 1997-11-10 1997-11-10 Sulfonamid-substituierte anellierte 5-Ring-Verbindungen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
ZA9810202B true ZA9810202B (en) 1999-05-10

Family

ID=7848065

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810202A ZA9810202B (en) 1997-11-10 1998-11-09 Sulfonamide-substituted fused 5-membered ring compounds their use as a medicament and pharmaceutical preparations comprising them

Country Status (29)

Country Link
US (1) US6015822A (xx)
EP (1) EP0915087B1 (xx)
JP (1) JP4331809B2 (xx)
KR (1) KR19990045147A (xx)
CN (1) CN1219533A (xx)
AR (1) AR016006A1 (xx)
AT (1) ATE236120T1 (xx)
AU (1) AU742199B2 (xx)
BR (1) BR9804995A (xx)
CA (1) CA2253211C (xx)
CZ (1) CZ363798A3 (xx)
DE (2) DE19749453A1 (xx)
DK (1) DK0915087T3 (xx)
ES (1) ES2196456T3 (xx)
HR (1) HRP980585B1 (xx)
HU (1) HUP9802590A3 (xx)
ID (1) ID21282A (xx)
IL (1) IL126955A (xx)
MY (1) MY115619A (xx)
NO (1) NO312546B1 (xx)
NZ (1) NZ332633A (xx)
PL (1) PL329596A1 (xx)
PT (1) PT915087E (xx)
RU (1) RU2223951C2 (xx)
SI (1) SI0915087T1 (xx)
SK (1) SK283866B6 (xx)
TR (1) TR199802270A2 (xx)
TW (1) TW427970B (xx)
ZA (1) ZA9810202B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100720844B1 (ko) 1998-07-08 2007-05-25 사노피-아벤티스 도이칠란트 게엠베하 황 치환된 설포닐아미노카복실산 ｎ-아릴아미드, 이의 제조방법, 및 이를 함유하는 약제학적 제제
DE19929076A1 (de) 1999-06-25 2000-12-28 Aventis Pharma Gmbh Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
US6458794B2 (en) 1999-12-21 2002-10-01 Icagen, Inc. Potassium channel inhibitors
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors
KR100581703B1 (ko) * 2001-12-12 2006-05-22 에프. 호프만-라 로슈 아게 아데노신 수용체 조절제로서의 벤조티오펜
US7119112B2 (en) * 2002-02-28 2006-10-10 Icagen, Inc. Sulfonamides as potassium channel blockers
AU2007208109B2 (en) * 2006-01-24 2012-08-23 Eli Lilly And Company Indole sulfonamide modulators of progesterone receptors
JP2009026126A (ja) * 2007-07-20 2009-02-05 Nec Electronics Corp 半導体装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1178868B (it) * 1983-03-04 1987-09-16 Otsuka Pharma Co Ltd Derivati dell indano e loro sali procedimento per la loro preparazione e composizioni che li contengono
DE3623944A1 (de) * 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof
US5914349A (en) * 1994-01-10 1999-06-22 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives

Also Published As

Publication number Publication date
CA2253211C (en) 2009-04-14
HUP9802590A2 (hu) 2000-04-28
KR19990045147A (ko) 1999-06-25
HRP980585A2 (en) 1999-06-30
ES2196456T3 (es) 2003-12-16
IL126955A (en) 2002-11-10
TR199802270A2 (xx) 1999-05-21
NZ332633A (en) 2000-05-26
JP4331809B2 (ja) 2009-09-16
RU2223951C2 (ru) 2004-02-20
HRP980585B1 (en) 2003-02-28
IL126955A0 (en) 1999-09-22
EP0915087A2 (de) 1999-05-12
ATE236120T1 (de) 2003-04-15
PT915087E (pt) 2003-08-29
HUP9802590A3 (en) 2001-08-28
SI0915087T1 (en) 2003-10-31
TW427970B (en) 2001-04-01
PL329596A1 (en) 1999-05-24
NO312546B1 (no) 2002-05-27
JPH11236368A (ja) 1999-08-31
DE19749453A1 (de) 1999-05-12
DK0915087T3 (da) 2003-07-21
MY115619A (en) 2003-07-31
CA2253211A1 (en) 1999-05-10
EP0915087A3 (de) 1999-07-21
CN1219533A (zh) 1999-06-16
AR016006A1 (es) 2001-05-30
AU9139898A (en) 1999-05-27
SK154598A3 (en) 1999-06-11
NO985171L (no) 1999-05-11
CZ363798A3 (cs) 1999-05-12
NO985171D0 (no) 1998-11-05
HU9802590D0 (en) 1999-01-28
EP0915087B1 (de) 2003-04-02
ID21282A (id) 1999-05-12
AU742199B2 (en) 2001-12-20
DE59807718D1 (de) 2003-05-08
SK283866B6 (sk) 2004-03-02
BR9804995A (pt) 2001-05-22
US6015822A (en) 2000-01-18

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