ATE243516T1 - Amoxicillin und clavulanat enthaltende arzneizubereitungen - Google Patents

Amoxicillin und clavulanat enthaltende arzneizubereitungen

Info

Publication number
ATE243516T1
ATE243516T1 AT98912303T AT98912303T ATE243516T1 AT E243516 T1 ATE243516 T1 AT E243516T1 AT 98912303 T AT98912303 T AT 98912303T AT 98912303 T AT98912303 T AT 98912303T AT E243516 T1 ATE243516 T1 AT E243516T1
Authority
AT
Austria
Prior art keywords
clavulanate
preparations containing
medicinal preparations
containing amoxicillin
amoxicillin
Prior art date
Application number
AT98912303T
Other languages
English (en)
Inventor
Jacky Andre Gustave Mention
Bordallo Jose Luis Sanroma
Kevin Storm
Original Assignee
Glaxosmithkline Lab Sas
Smithkline Beecham Sa
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9703100.9A external-priority patent/GB9703100D0/en
Priority claimed from GBGB9703099.3A external-priority patent/GB9703099D0/en
Priority claimed from GBGB9703101.7A external-priority patent/GB9703101D0/en
Application filed by Glaxosmithkline Lab Sas, Smithkline Beecham Sa, Smithkline Beecham Corp filed Critical Glaxosmithkline Lab Sas
Application granted granted Critical
Publication of ATE243516T1 publication Critical patent/ATE243516T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
AT98912303T 1997-02-14 1998-02-10 Amoxicillin und clavulanat enthaltende arzneizubereitungen ATE243516T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9703100.9A GB9703100D0 (en) 1997-02-14 1997-02-14 Formulations
GBGB9703099.3A GB9703099D0 (en) 1997-02-14 1997-02-14 Formulations
GBGB9703101.7A GB9703101D0 (en) 1997-02-14 1997-02-14 Formulations
PCT/EP1998/000811 WO1998035672A1 (en) 1997-02-14 1998-02-10 Pharmaceutical formulations comprising amoxocyllin and clavulanate

Publications (1)

Publication Number Publication Date
ATE243516T1 true ATE243516T1 (de) 2003-07-15

Family

ID=27268719

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98912303T ATE243516T1 (de) 1997-02-14 1998-02-10 Amoxicillin und clavulanat enthaltende arzneizubereitungen

Country Status (25)

Country Link
EP (2) EP0975342B1 (de)
JP (1) JP2001512451A (de)
KR (1) KR100499812B1 (de)
CN (1) CN1194687C (de)
AP (1) AP1253A (de)
AT (1) ATE243516T1 (de)
AU (1) AU728526B2 (de)
BG (1) BG103664A (de)
BR (1) BR9807383A (de)
CA (1) CA2280857A1 (de)
DE (1) DE69815833T2 (de)
DZ (1) DZ2420A1 (de)
EA (1) EA002595B1 (de)
ES (1) ES2201468T3 (de)
HK (1) HK1043041A1 (de)
ID (1) ID23673A (de)
IL (1) IL131201A (de)
MA (1) MA24473A1 (de)
NO (1) NO993887L (de)
NZ (1) NZ337043A (de)
OA (1) OA11087A (de)
PL (1) PL334976A1 (de)
SK (1) SK110299A3 (de)
TR (1) TR199901961T2 (de)
WO (1) WO1998035672A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416600D0 (en) * 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
CN1289084C (zh) 1995-09-07 2006-12-13 史密丝克莱恩比彻姆有限公司 药物制剂
GB9815532D0 (en) * 1998-07-17 1998-09-16 Lek Pharmaceutical & Cvhemical Pharmaceutical suspension formulation
WO2000050036A1 (en) * 1999-02-26 2000-08-31 Biovail International Ltd. Storage stable amoxycillin and clavulanate suspension composition
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
SK285140B6 (sk) * 1999-04-13 2006-07-07 Beecham Pharmaceuticals (Pte) Limited Použitie amoxycilínu a klavulanátu draselného a farmaceutický prípravok s ich obsahom
ATE334655T1 (de) * 1999-08-20 2006-08-15 Glaxosmithkline Lab Sas Amoxicillin und clavulanat enthaltende pharmazeutische formulierung
FR2797588B1 (fr) * 1999-08-20 2003-08-01 Smithkline Beecham Lab Formulation pharmaceutique a base d'amoxycilline et de clavulanate
US6541025B1 (en) * 1999-12-30 2003-04-01 Shear/Kershman Laboratories, Inc. Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
WO2002030392A2 (en) 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
AT413983B (de) * 2001-04-12 2006-08-15 Sandoz Ag K-clavulanat in der form eines granulates
AT412344B (de) * 2001-04-12 2005-01-25 Sandoz Ag Hydrophobisierte teilchen von k-clavulanat
AU2003208358A1 (en) * 2002-02-01 2003-09-02 Sandoz Gmbh Demixing-stable granulate
BR0312728A (pt) * 2002-07-16 2005-04-26 Ranbaxy Lab Ltd Formulação em tablete dispersìvel e processo para sua preparação
RU2343931C2 (ru) * 2003-06-16 2009-01-20 Глаксо Груп Лимитед Фармацевтические препараты, содержащие амоксициллин и клавуланат
CN1968682A (zh) * 2004-06-18 2007-05-23 株式会社柳韩洋行 包含表面改性的碳酸氢钠的阿莫西林和/或克拉维酸口服分散片组合物
SI21912A (sl) * 2004-12-24 2006-06-30 Lek Farmacevtska Druzba D.D. Stabilne farmacevtske oblike, ki vsebujejo amoksicilin in klavulansko kislino
DE102006007830A1 (de) * 2006-02-17 2007-08-30 Grünenthal GmbH Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure
CN100464750C (zh) * 2006-02-23 2009-03-04 珠海联邦制药股份有限公司 一种制备含阿莫西林钠和克拉维酸钾的药物混合物的方法
FI20080352A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi korkean lääkepitoisuuden tabletin valmistamiseksi
US8951562B2 (en) 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20080351A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi
FI20070521L (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
EP2291233B1 (de) 2008-05-09 2019-09-04 Atacama Labs Oy Verfahren für trockene granulation
CN102861015B (zh) * 2011-07-05 2015-07-08 北京乐维生物技术有限公司 一种稳定的阿莫西林克拉维酸钾缓释制剂及其制备工艺
WO2014065769A1 (en) * 2012-10-22 2014-05-01 Bilgiç Mahmut Formulations for oral suspensions comprising antibiotics
EP3046548B1 (de) 2013-09-20 2020-02-12 Centrient Pharmaceuticals Netherlands B.V. Tablette mit crospovidon
US9254261B2 (en) * 2014-03-03 2016-02-09 Sandoz Ag Stable quick dissolving dosage form comprising amoxicillin and clavulanic acid
MX2022000250A (es) 2019-07-05 2022-02-03 Glaxosmithkline Ip No 2 Ltd Streptomyces clavuligerus.
CN113274357B (zh) * 2021-05-28 2022-12-27 广州白云山医药集团股份有限公司白云山制药总厂 一种阿莫西林药物及其制备方法
CN114869884A (zh) * 2021-07-30 2022-08-09 江苏恒丰强生物技术有限公司 一种用于猪呼吸道疾病的复方阿莫西林粉及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
US4140764A (en) * 1974-12-18 1979-02-20 Beecham Group Limited β-Lactamase inhibitors and process for their preparation
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
EP1034784A3 (de) * 1993-01-22 2001-06-27 Smithkline Beecham Plc Pharmazeutische Zusammensetzungen, die Clavulansäure und ein antibakterielle Mittel enthalten
IL109770A0 (en) * 1993-05-29 1994-11-28 Smithkline Beecham Corp Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby
GB9402203D0 (en) * 1994-02-04 1994-03-30 Smithkline Beecham Plc Pharmaceutical formulation
GB9405856D0 (en) * 1994-03-24 1994-05-11 Smithkline Beecham Plc Pharmaceutical formulation
GB9407386D0 (en) * 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
DZ1926A1 (fr) * 1994-09-03 2002-02-17 Smithkline Beckman P L C Formulations pharmaceutiques.

Also Published As

Publication number Publication date
EP1142574A1 (de) 2001-10-10
DZ2420A1 (fr) 2003-01-04
WO1998035672A1 (en) 1998-08-20
BR9807383A (pt) 2000-03-14
NO993887D0 (no) 1999-08-12
KR20000071076A (ko) 2000-11-25
TR199901961T2 (xx) 1999-11-22
AP9901623A0 (en) 1999-09-30
EA002595B1 (ru) 2002-06-27
EP0975342B1 (de) 2003-06-25
IL131201A (en) 2005-06-19
EP0975342A1 (de) 2000-02-02
CA2280857A1 (en) 1998-08-20
CN1251990A (zh) 2000-05-03
IL131201A0 (en) 2001-01-28
AU728526B2 (en) 2001-01-11
AP1253A (en) 2004-03-17
JP2001512451A (ja) 2001-08-21
BG103664A (en) 2000-03-31
MA24473A1 (fr) 1998-10-01
NZ337043A (en) 2001-02-23
OA11087A (en) 2003-03-13
PL334976A1 (en) 2000-03-27
AU6719698A (en) 1998-09-08
DE69815833T2 (de) 2004-05-19
EA199900647A1 (ru) 2000-06-26
NO993887L (no) 1999-08-12
HK1043041A1 (zh) 2002-09-06
KR100499812B1 (ko) 2005-07-08
CN1194687C (zh) 2005-03-30
SK110299A3 (en) 2000-08-14
DE69815833D1 (de) 2003-07-31
ES2201468T3 (es) 2004-03-16
ID23673A (id) 2000-05-11

Similar Documents

Publication Publication Date Title
ATE243516T1 (de) Amoxicillin und clavulanat enthaltende arzneizubereitungen
DE69521799T2 (de) Polymer umhüllte tablette enthaltend amoxicillin und clavulanat
KR950703566A (ko) 티에노디아제핀 화합물 및 그의 의약 용도[thienodiazepine compound and medicinal use thereof]
ATE288419T1 (de) Alpha-aryl-n-alkylnitrone sowie diese enthaltende pharmazeutische zubereitungen
BR9500784A (pt) Composto e formulação farmacêutica
DE69618587D1 (de) Chinazoline und pharmazeutische zusammensetzungen
DE69814091D1 (de) Voriconazol-enthaltende pharmazeutische zubereitungen
HK1043042A1 (zh) 含有阿莫西林和棒酸鹽的藥用加工製劑
DE59813619D1 (de) Ascorbinsäurederivate enthaltende kosmetische und pharmazeutische Zubereitungen
DE69320242D1 (de) Medizinische Selbstklebefolie und Arzneimittelzubereitung
DE69732649D1 (de) Heteroarylsulfonamidderivate und diese enthaltende pharmazeutische zubereitungen
BR9602915A (pt) Medicamentos uso e formulação farmacêutica
NO305903B1 (no) Benzonitriler og benzofluorider, legemidler bestående av forbindelsene, farmasöytiske preparater inneholdende forbindelsene, samt anvendelse av forbindelsene for fremstilling av farmasöytiske preparater
BR9610983A (pt) Formas estáveis de administração farmacêuticas contendo paratormônio
FI965204A0 (fi) Bromelaiinin lääkekäyttö
DE69828442D1 (de) Kombinationspräparate enthaltend statin und karboxyalkyläther
DK0994706T3 (da) Præparater til oral indgivelse af taxaner og anvendelse deraf
DE4494713T1 (de) Arylsulfonamidderivate und diese Derivate enthaltende Arzneimittel
NO20001717D0 (no) Serotonin-inneholdende formulering for oral administrering og anvendelse av samme
DE69827417D1 (de) Tizoxanide und/oder Nitazoxanide enthaltende pharmazeutische Zubereitungen
EE9800275A (et) Misolastiini sisaldavad prolongeeritud toimega farmatseutilised preparaadid
DE69800970D1 (de) Pyridinderivate und sie enthaltende pharmazeutische zubereitungen
FI973230A0 (fi) Uusi farmaseuttinen formulaatio
DE69813624D1 (de) Gemisch und pharmazeutische zubereitung enthaltend z-4-hydroxytamoxifen und cyclodextrin
BR9606066A (pt) Composto e formulação farmacêutica

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties