IL131201A - Pharmaceutical formulations comprising amoxycillin and clavulanate - Google Patents
Pharmaceutical formulations comprising amoxycillin and clavulanateInfo
- Publication number
- IL131201A IL131201A IL13120198A IL13120198A IL131201A IL 131201 A IL131201 A IL 131201A IL 13120198 A IL13120198 A IL 13120198A IL 13120198 A IL13120198 A IL 13120198A IL 131201 A IL131201 A IL 131201A
- Authority
- IL
- Israel
- Prior art keywords
- amoxycillin
- clavulanate
- pharmaceutical formulations
- formulations
- pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9703101.7A GB9703101D0 (en) | 1997-02-14 | 1997-02-14 | Formulations |
GBGB9703099.3A GB9703099D0 (en) | 1997-02-14 | 1997-02-14 | Formulations |
GBGB9703100.9A GB9703100D0 (en) | 1997-02-14 | 1997-02-14 | Formulations |
PCT/EP1998/000811 WO1998035672A1 (en) | 1997-02-14 | 1998-02-10 | Pharmaceutical formulations comprising amoxocyllin and clavulanate |
Publications (2)
Publication Number | Publication Date |
---|---|
IL131201A0 IL131201A0 (en) | 2001-01-28 |
IL131201A true IL131201A (en) | 2005-06-19 |
Family
ID=27268719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13120198A IL131201A (en) | 1997-02-14 | 1998-02-10 | Pharmaceutical formulations comprising amoxycillin and clavulanate |
Country Status (25)
Country | Link |
---|---|
EP (2) | EP1142574A1 (xx) |
JP (1) | JP2001512451A (xx) |
KR (1) | KR100499812B1 (xx) |
CN (1) | CN1194687C (xx) |
AP (1) | AP1253A (xx) |
AT (1) | ATE243516T1 (xx) |
AU (1) | AU728526B2 (xx) |
BG (1) | BG103664A (xx) |
BR (1) | BR9807383A (xx) |
CA (1) | CA2280857A1 (xx) |
DE (1) | DE69815833T2 (xx) |
DZ (1) | DZ2420A1 (xx) |
EA (1) | EA002595B1 (xx) |
ES (1) | ES2201468T3 (xx) |
HK (1) | HK1043041A1 (xx) |
ID (1) | ID23673A (xx) |
IL (1) | IL131201A (xx) |
MA (1) | MA24473A1 (xx) |
NO (1) | NO993887D0 (xx) |
NZ (1) | NZ337043A (xx) |
OA (1) | OA11087A (xx) |
PL (1) | PL334976A1 (xx) |
SK (1) | SK110299A3 (xx) |
TR (1) | TR199901961T2 (xx) |
WO (1) | WO1998035672A1 (xx) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9416600D0 (en) * | 1994-08-17 | 1994-10-12 | Smithkline Beecham Plc | Pharmaceutical formulation |
BR9610396A (pt) | 1995-09-07 | 1999-07-06 | Smithkline Beecham Corp | Formulação farmacêutica |
GB9815532D0 (en) * | 1998-07-17 | 1998-09-16 | Lek Pharmaceutical & Cvhemical | Pharmaceutical suspension formulation |
WO2000050036A1 (en) * | 1999-02-26 | 2000-08-31 | Biovail International Ltd. | Storage stable amoxycillin and clavulanate suspension composition |
US6294199B1 (en) * | 1999-04-13 | 2001-09-25 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising administering amoxycillin |
US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
ATE242629T1 (de) * | 1999-04-13 | 2003-06-15 | Beecham Pharm Pte Ltd | Neue behandlungsmethode unter verwendung einer hochdosierten form von amoxycillin und kaliumclavulanat |
AU6571400A (en) | 1999-08-20 | 2001-03-19 | Smithkline Beecham Laboratoires Pharmaceutiques S.A.S. | Pharmaceutical formulation comprising amoxycillin and clavulanate |
FR2797588B1 (fr) * | 1999-08-20 | 2003-08-01 | Smithkline Beecham Lab | Formulation pharmaceutique a base d'amoxycilline et de clavulanate |
US6541025B1 (en) * | 1999-12-30 | 2003-04-01 | Shear/Kershman Laboratories, Inc. | Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals |
US6375982B1 (en) * | 2000-07-05 | 2002-04-23 | Capricorn Pharma, Inc. | Rapid-melt semi-solid compositions, methods of making same and method of using same |
WO2002030392A2 (en) | 2000-10-12 | 2002-04-18 | Beecham Pharmaceuticals (Pte) Limited | Formulation containing amoxicillin |
US6756057B2 (en) | 2000-10-12 | 2004-06-29 | Beecham Pharmaceuticals (Pte) Limited | Amoxicillin and potassium clavulanate dosage form |
AT412344B (de) * | 2001-04-12 | 2005-01-25 | Sandoz Ag | Hydrophobisierte teilchen von k-clavulanat |
AT413983B (de) * | 2001-04-12 | 2006-08-15 | Sandoz Ag | K-clavulanat in der form eines granulates |
AU2003208358A1 (en) * | 2002-02-01 | 2003-09-02 | Sandoz Gmbh | Demixing-stable granulate |
EA200500213A1 (ru) * | 2002-07-16 | 2005-08-25 | Рэнбакси Лабораториз Лимитед | Диспергируемые таблетки для орального назначения |
AU2004246811A1 (en) * | 2003-06-16 | 2004-12-23 | Glaxo Group Limited | Pharmaceutical formulations comprising amoxicillin and clavulanate |
CN1968682A (zh) * | 2004-06-18 | 2007-05-23 | 株式会社柳韩洋行 | 包含表面改性的碳酸氢钠的阿莫西林和/或克拉维酸口服分散片组合物 |
SI21912A (sl) * | 2004-12-24 | 2006-06-30 | Lek Farmacevtska Druzba D.D. | Stabilne farmacevtske oblike, ki vsebujejo amoksicilin in klavulansko kislino |
DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
CN100464750C (zh) * | 2006-02-23 | 2009-03-04 | 珠海联邦制药股份有限公司 | 一种制备含阿莫西林钠和克拉维酸钾的药物混合物的方法 |
US8951562B2 (en) | 2006-11-10 | 2015-02-10 | Atacama Labs Oy | Method and apparatus or dry granulation |
FI20070521L (fi) | 2006-11-10 | 2008-05-11 | Atacama Labs Oy | Rakeita, tabletteja ja rakeistusmenetelmä |
FI20080351A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi |
FI20080352A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi korkean lääkepitoisuuden tabletin valmistamiseksi |
EP2291233B1 (en) | 2008-05-09 | 2019-09-04 | Atacama Labs Oy | Method for dry granulation |
CN102861015B (zh) * | 2011-07-05 | 2015-07-08 | 北京乐维生物技术有限公司 | 一种稳定的阿莫西林克拉维酸钾缓释制剂及其制备工艺 |
WO2014065769A1 (en) * | 2012-10-22 | 2014-05-01 | Bilgiç Mahmut | Formulations for oral suspensions comprising antibiotics |
CN105555261B (zh) * | 2013-09-20 | 2020-02-11 | 灿盛制药有限公司荷兰公司 | 包含交聚维酮的片剂 |
US9254261B2 (en) * | 2014-03-03 | 2016-02-09 | Sandoz Ag | Stable quick dissolving dosage form comprising amoxicillin and clavulanic acid |
EP3994154A1 (en) | 2019-07-05 | 2022-05-11 | GlaxoSmithKline Intellectual Property (No.2) Limited | Streptomyces clavuligerus |
CN113274357B (zh) * | 2021-05-28 | 2022-12-27 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种阿莫西林药物及其制备方法 |
CN114869884A (zh) * | 2021-07-30 | 2022-08-09 | 江苏恒丰强生物技术有限公司 | 一种用于猪呼吸道疾病的复方阿莫西林粉及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4110165A (en) * | 1974-04-20 | 1978-08-29 | Beecham Group Limited | Process for the production of clavulanic acid |
US4140764A (en) * | 1974-12-18 | 1979-02-20 | Beecham Group Limited | β-Lactamase inhibitors and process for their preparation |
JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
NZ198241A (en) * | 1980-09-27 | 1983-12-16 | Beecham Group Ltd | Tablet containing amoxycillin and potassium clavulanate |
GB9109862D0 (en) * | 1991-05-08 | 1991-07-03 | Beecham Lab Sa | Pharmaceutical formulations |
EP1034784A3 (en) * | 1993-01-22 | 2001-06-27 | Smithkline Beecham Plc | Pharmaceutical formulations containing clavulanic acid and an antibacterial agent |
IL109770A0 (en) * | 1993-05-29 | 1994-11-28 | Smithkline Beecham Corp | Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby |
GB9402203D0 (en) * | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Pharmaceutical formulation |
GB9405856D0 (en) * | 1994-03-24 | 1994-05-11 | Smithkline Beecham Plc | Pharmaceutical formulation |
GB9407386D0 (en) * | 1994-04-14 | 1994-06-08 | Smithkline Beecham Plc | Pharmaceutical formulation |
GB9408117D0 (en) * | 1994-04-23 | 1994-06-15 | Smithkline Beecham Corp | Pharmaceutical formulations |
DZ1926A1 (fr) * | 1994-09-03 | 2002-02-17 | Smithkline Beckman P L C | Formulations pharmaceutiques. |
-
1998
- 1998-02-10 PL PL98334976A patent/PL334976A1/xx unknown
- 1998-02-10 IL IL13120198A patent/IL131201A/xx not_active IP Right Cessation
- 1998-02-10 JP JP53535198A patent/JP2001512451A/ja not_active Ceased
- 1998-02-10 EP EP01201884A patent/EP1142574A1/en not_active Ceased
- 1998-02-10 TR TR1999/01961T patent/TR199901961T2/xx unknown
- 1998-02-10 CN CNB988040956A patent/CN1194687C/zh not_active Expired - Fee Related
- 1998-02-10 AU AU67196/98A patent/AU728526B2/en not_active Ceased
- 1998-02-10 AP APAP/P/1999/001623A patent/AP1253A/en active
- 1998-02-10 WO PCT/EP1998/000811 patent/WO1998035672A1/en not_active Application Discontinuation
- 1998-02-10 BR BR9807383-4A patent/BR9807383A/pt not_active Application Discontinuation
- 1998-02-10 CA CA002280857A patent/CA2280857A1/en not_active Abandoned
- 1998-02-10 ES ES98912303T patent/ES2201468T3/es not_active Expired - Lifetime
- 1998-02-10 KR KR10-1999-7007362A patent/KR100499812B1/ko not_active IP Right Cessation
- 1998-02-10 AT AT98912303T patent/ATE243516T1/de not_active IP Right Cessation
- 1998-02-10 ID IDW990859D patent/ID23673A/id unknown
- 1998-02-10 EA EA199900647A patent/EA002595B1/ru not_active IP Right Cessation
- 1998-02-10 NZ NZ337043A patent/NZ337043A/en unknown
- 1998-02-10 DE DE69815833T patent/DE69815833T2/de not_active Expired - Lifetime
- 1998-02-10 SK SK1102-99A patent/SK110299A3/sk unknown
- 1998-02-10 EP EP98912303A patent/EP0975342B1/en not_active Expired - Lifetime
- 1998-02-11 DZ DZ980030A patent/DZ2420A1/xx active
- 1998-02-12 MA MA24964A patent/MA24473A1/fr unknown
-
1999
- 1999-08-12 NO NO993887A patent/NO993887D0/no unknown
- 1999-08-13 BG BG103664A patent/BG103664A/xx unknown
- 1999-08-13 OA OA9900181A patent/OA11087A/en unknown
-
2000
- 2000-07-26 HK HK02102072.5A patent/HK1043041A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CN1194687C (zh) | 2005-03-30 |
WO1998035672A1 (en) | 1998-08-20 |
PL334976A1 (en) | 2000-03-27 |
AP1253A (en) | 2004-03-17 |
JP2001512451A (ja) | 2001-08-21 |
AU728526B2 (en) | 2001-01-11 |
ATE243516T1 (de) | 2003-07-15 |
HK1043041A1 (zh) | 2002-09-06 |
DZ2420A1 (fr) | 2003-01-04 |
EP1142574A1 (en) | 2001-10-10 |
NO993887L (no) | 1999-08-12 |
EP0975342B1 (en) | 2003-06-25 |
SK110299A3 (en) | 2000-08-14 |
BR9807383A (pt) | 2000-03-14 |
AP9901623A0 (en) | 1999-09-30 |
ID23673A (id) | 2000-05-11 |
CN1251990A (zh) | 2000-05-03 |
ES2201468T3 (es) | 2004-03-16 |
KR100499812B1 (ko) | 2005-07-08 |
EA002595B1 (ru) | 2002-06-27 |
MA24473A1 (fr) | 1998-10-01 |
EP0975342A1 (en) | 2000-02-02 |
EA199900647A1 (ru) | 2000-06-26 |
TR199901961T2 (xx) | 1999-11-22 |
OA11087A (en) | 2003-03-13 |
BG103664A (en) | 2000-03-31 |
NO993887D0 (no) | 1999-08-12 |
KR20000071076A (ko) | 2000-11-25 |
CA2280857A1 (en) | 1998-08-20 |
IL131201A0 (en) | 2001-01-28 |
DE69815833D1 (de) | 2003-07-31 |
AU6719698A (en) | 1998-09-08 |
DE69815833T2 (de) | 2004-05-19 |
NZ337043A (en) | 2001-02-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees | ||
MM9K | Patent not in force due to non-payment of renewal fees |