ATE334655T1 - Amoxicillin und clavulanat enthaltende pharmazeutische formulierung - Google Patents
Amoxicillin und clavulanat enthaltende pharmazeutische formulierungInfo
- Publication number
- ATE334655T1 ATE334655T1 AT00202882T AT00202882T ATE334655T1 AT E334655 T1 ATE334655 T1 AT E334655T1 AT 00202882 T AT00202882 T AT 00202882T AT 00202882 T AT00202882 T AT 00202882T AT E334655 T1 ATE334655 T1 AT E334655T1
- Authority
- AT
- Austria
- Prior art keywords
- clavulanate
- pharmaceutical formulation
- formulation containing
- flavour
- containing amoxicillin
- Prior art date
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 2
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title abstract 2
- 229960003022 amoxicillin Drugs 0.000 title abstract 2
- 229940090805 clavulanate Drugs 0.000 title abstract 2
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 2
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000796 flavoring agent Substances 0.000 abstract 4
- 235000019634 flavors Nutrition 0.000 abstract 3
- 235000016623 Fragaria vesca Nutrition 0.000 abstract 1
- 240000009088 Fragaria x ananassa Species 0.000 abstract 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9919840.0A GB9919840D0 (en) | 1999-08-20 | 1999-08-20 | Pharmaceutical formulation |
| GBGB9920150.1A GB9920150D0 (en) | 1999-08-25 | 1999-08-25 | Pharmaceuticals formulation |
| GB0019084A GB0019084D0 (en) | 2000-08-03 | 2000-08-03 | Pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE334655T1 true ATE334655T1 (de) | 2006-08-15 |
Family
ID=27255829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00202882T ATE334655T1 (de) | 1999-08-20 | 2000-08-17 | Amoxicillin und clavulanat enthaltende pharmazeutische formulierung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6977086B1 (de) |
| EP (1) | EP1078627B1 (de) |
| AT (1) | ATE334655T1 (de) |
| AU (1) | AU6571400A (de) |
| DE (1) | DE60029698T2 (de) |
| DK (1) | DK1078627T3 (de) |
| ES (1) | ES2269063T3 (de) |
| PT (1) | PT1078627E (de) |
| WO (1) | WO2001013883A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7250176B1 (en) | 1999-04-13 | 2007-07-31 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection |
| US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
| BRPI0411524A (pt) * | 2003-06-16 | 2006-08-01 | Glaxo Group Ltd | formulação farmacêutica de amoxicilina e clavulanato, uso de carboximetilcelulose de sódio, e, método de tratar infecção bacteriana em pacientes pediátricos |
| GB0313913D0 (en) * | 2003-06-16 | 2003-07-23 | Beecham Pharm Pte Ltd | New use |
| US20070134277A1 (en) * | 2005-12-09 | 2007-06-14 | Children's Medical Center Corporation | Pharmaceutical formulation for sulfur-containing drugs in liquid dosage forms |
| DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
| CA2661576A1 (en) * | 2006-09-26 | 2008-04-03 | Taro Pharmaceuticals North America, Inc. | Stabilizing compositions for antibiotics and methods of use |
| CN101406450B (zh) * | 2007-10-12 | 2010-08-25 | 河南农业大学 | 复方阿莫西林油混悬注射液制备工艺 |
| WO2010132662A1 (en) * | 2009-05-13 | 2010-11-18 | Relypsa, Inc. | Powder formulations of potassium-binding active agents |
| KR101486999B1 (ko) * | 2009-07-22 | 2015-01-28 | 씨제이제일제당 주식회사 | 신규한 락토바실러스 플란타룸 및 이를 포함하는 조성물 |
| KR101178217B1 (ko) | 2009-10-28 | 2012-09-07 | 씨제이제일제당 (주) | 신규한 락토바실러스 플란타룸 및 이를 포함하는 조성물 |
| TWI463998B (zh) * | 2009-12-31 | 2014-12-11 | Synmosa Biopharma Corp | Amoxicillin and clomycin have a high absorption rate of pharmaceutical ingredients |
| CN114668724B (zh) * | 2020-12-24 | 2023-08-22 | 鲁南制药集团股份有限公司 | 一种阿莫西林克拉维酸钾干混悬剂及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5114929A (en) * | 1989-03-21 | 1992-05-19 | Beecham Group P.L.C. | Pharmaceutical formulation |
| US5861172A (en) * | 1991-05-08 | 1999-01-19 | Laboratorios Beecham Sa | Pharmaceutical formulations of compacted granulates of β-lactam antibiotics |
| EA002595B1 (ru) | 1997-02-14 | 2002-06-27 | Смитклайн Бичем Лаборатуар Фармасетик | Фармацевтический препарат, содержащий амоксициллин и клавуланат, способ его приготовления и гранулят, содержащий амоксициллин и клавуланат |
| GB9815532D0 (en) * | 1998-07-17 | 1998-09-16 | Lek Pharmaceutical & Cvhemical | Pharmaceutical suspension formulation |
-
2000
- 2000-08-17 AU AU65714/00A patent/AU6571400A/en not_active Abandoned
- 2000-08-17 US US10/069,681 patent/US6977086B1/en not_active Expired - Fee Related
- 2000-08-17 PT PT00202882T patent/PT1078627E/pt unknown
- 2000-08-17 AT AT00202882T patent/ATE334655T1/de not_active IP Right Cessation
- 2000-08-17 WO PCT/EP2000/008048 patent/WO2001013883A1/en not_active Ceased
- 2000-08-17 EP EP00202882A patent/EP1078627B1/de not_active Expired - Lifetime
- 2000-08-17 ES ES00202882T patent/ES2269063T3/es not_active Expired - Lifetime
- 2000-08-17 DK DK00202882T patent/DK1078627T3/da active
- 2000-08-17 DE DE60029698T patent/DE60029698T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1078627A1 (de) | 2001-02-28 |
| WO2001013883A1 (en) | 2001-03-01 |
| DK1078627T3 (da) | 2006-11-13 |
| AU6571400A (en) | 2001-03-19 |
| ES2269063T3 (es) | 2007-04-01 |
| US6977086B1 (en) | 2005-12-20 |
| DE60029698D1 (de) | 2006-09-14 |
| EP1078627B1 (de) | 2006-08-02 |
| DE60029698T2 (de) | 2007-08-02 |
| PT1078627E (pt) | 2006-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1078627 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |