IL126553A0 - Glial cell line-derived neurotrophic factor receptor - Google Patents
Glial cell line-derived neurotrophic factor receptorInfo
- Publication number
- IL126553A0 IL126553A0 IL12655397A IL12655397A IL126553A0 IL 126553 A0 IL126553 A0 IL 126553A0 IL 12655397 A IL12655397 A IL 12655397A IL 12655397 A IL12655397 A IL 12655397A IL 126553 A0 IL126553 A0 IL 126553A0
- Authority
- IL
- Israel
- Prior art keywords
- gdnf
- gdnfr
- receptor
- cell line
- neurotrophic factor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Plant Pathology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1590796P | 1996-04-22 | 1996-04-22 | |
US1722196P | 1996-05-09 | 1996-05-09 | |
US08/837,199 US6455277B1 (en) | 1996-04-22 | 1997-04-14 | Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides |
PCT/US1997/006281 WO1997040152A1 (en) | 1996-04-22 | 1997-04-15 | Glial cell line-derived neurotrophic factor receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
IL126553A0 true IL126553A0 (en) | 1999-08-17 |
Family
ID=27360445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12655397A IL126553A0 (en) | 1996-04-22 | 1997-04-15 | Glial cell line-derived neurotrophic factor receptor |
Country Status (19)
Country | Link |
---|---|
US (3) | US6455277B1 (no) |
EP (1) | EP0909316B1 (no) |
JP (1) | JP2000509271A (no) |
KR (1) | KR20000010571A (no) |
CN (1) | CN1219967A (no) |
AT (1) | ATE338115T1 (no) |
AU (1) | AU720092B2 (no) |
BR (1) | BR9708959A (no) |
CA (1) | CA2250704C (no) |
CZ (1) | CZ324598A3 (no) |
DE (1) | DE69736597T2 (no) |
EA (1) | EA002924B1 (no) |
ES (1) | ES2271968T3 (no) |
HU (1) | HUP9902640A3 (no) |
IL (1) | IL126553A0 (no) |
NO (1) | NO984757L (no) |
NZ (1) | NZ332256A (no) |
SK (1) | SK140398A3 (no) |
WO (1) | WO1997040152A1 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6696259B1 (en) * | 1995-11-13 | 2004-02-24 | Licentia Ltd. | Assays using glial cell line-derived neurotrophic factor receptors |
WO1997044356A2 (en) * | 1996-05-08 | 1997-11-27 | Biogen, Inc. | RET LIGAND (RetL) FOR STIMULATING NEURAL AND RENAL GROWTH |
US6677135B1 (en) * | 1996-05-08 | 2004-01-13 | Biogen, Inc. | Ret ligand (RetL) for stimulating neutral and renal growth |
US20020068361A1 (en) * | 1997-04-08 | 2002-06-06 | Douglas Clary | Methods of evaluating specific cellular functions of receptor protein tyrosine kinases in a ligand independent manner |
AU7165998A (en) * | 1997-05-30 | 1998-12-30 | Amgen, Inc. | Neurotrophic factor receptors |
US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
DE19816186A1 (de) * | 1998-04-14 | 1999-10-21 | Univ Muenchen L Maximilians | GDNF-kodierende DNA, Teile davon und GDNF-Varianten |
FI20000394A0 (fi) * | 2000-02-21 | 2000-02-21 | Airaksinen Matti | GFRa4:n sukuisia tai siitä johdettuja aineita sekä niiden käyttö |
HUE025347T2 (en) | 2003-03-19 | 2016-02-29 | Biogen Ma Inc | NOGO receptor binding protein |
US20060239966A1 (en) * | 2003-10-20 | 2006-10-26 | Tornoee Jens | In vivo gene therapy of parkinson's disease |
ES2395094T3 (es) | 2004-06-24 | 2013-02-08 | Biogen Idec Ma Inc. | Tratamiento de afecciones que implican la desmielinización |
AU2005294200A1 (en) * | 2004-10-08 | 2006-04-20 | Georgia Tech Research Corporation | Microencapsulation of cells in hydrogels using electrostatic potentials |
PT1904104E (pt) | 2005-07-08 | 2013-11-21 | Biogen Idec Inc | Anticorpos sp35 e suas utilizações |
MX2008005764A (es) * | 2005-11-04 | 2008-11-18 | Biogen Idec Inc | Metodos para promover el crecimiento de neuritas y la supervivencia en neuronas dopaminergicas. |
EP2315779A2 (en) | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
CA2873623C (en) | 2012-05-14 | 2021-11-09 | Biogen Idec Ma Inc. | Lingo-2 antagonists for treatment of conditions involving motor neurons |
MX2017009038A (es) | 2015-01-08 | 2017-10-25 | Biogen Ma Inc | Antagonistas de proteina 1 de interacción con el receptor de nogo que contiene el dominio de inmunoglobulina y repeticiones ricas en leucina (lingo-1) y usos para el tratamiento de trastornos desmielinizantes. |
WO2018089702A1 (en) | 2016-11-10 | 2018-05-17 | Keros Therapeutics, Inc. | Gdnf fusion polypeptides and methods of use thereof |
RU2690498C1 (ru) * | 2018-05-17 | 2019-06-04 | Федеральное государственное бюджетное научное учреждение "Медико-генетический научный центр" | Способ получения ноотропной композиции на основе полипептидных комплексов, выделенных из нейронов и глиальных клеток, полученных методом направленной дифференцировки индуцированных плюрипотентных стволовых клеток человека |
RU2732600C1 (ru) * | 2019-12-26 | 2020-09-21 | Федеральное государственное бюджетное научное учреждение "Медико-генетический научный центр имени академика Н.П. Бочкова" | Ноотропная композиция на основе полипептидных комплексов, выделенных из нейрональных прогениторных клеток в условиях гипоксии, и способ ее получения |
RU2752906C2 (ru) * | 2019-12-26 | 2021-08-11 | Федеральное государственное бюджетное научное учреждение "Медико-генетический научный центр имени академика Н.П. Бочкова" | Ноотропная композиция на основе полипептидных комплексов, выделенных из нейрональных прогениторных клеток в условиях теплового шока, и способ ее получения |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
US4892538A (en) | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
US5106627A (en) | 1987-11-17 | 1992-04-21 | Brown University Research Foundation | Neurological therapy devices |
US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
WO1990006952A1 (en) | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
JP2877509B2 (ja) | 1989-05-19 | 1999-03-31 | アムジエン・インコーポレーテツド | メタロプロテイナーゼ阻害剤 |
HU220795B1 (hu) | 1991-09-20 | 2002-05-28 | Amgen Inc. | Gliasejtvonal-eredetű neurotróf faktorfehérjék, továbbá berendezések és gyógyászati készítmények idegsejtkárosodás megelőzésére és kezelésére |
US5658785A (en) | 1994-06-06 | 1997-08-19 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
-
1997
- 1997-04-14 US US08/837,199 patent/US6455277B1/en not_active Expired - Lifetime
- 1997-04-15 IL IL12655397A patent/IL126553A0/xx unknown
- 1997-04-15 AU AU27309/97A patent/AU720092B2/en not_active Ceased
- 1997-04-15 CA CA002250704A patent/CA2250704C/en not_active Expired - Fee Related
- 1997-04-15 AT AT97921203T patent/ATE338115T1/de not_active IP Right Cessation
- 1997-04-15 CN CN97194013A patent/CN1219967A/zh active Pending
- 1997-04-15 SK SK1403-98A patent/SK140398A3/sk unknown
- 1997-04-15 WO PCT/US1997/006281 patent/WO1997040152A1/en active IP Right Grant
- 1997-04-15 ES ES97921203T patent/ES2271968T3/es not_active Expired - Lifetime
- 1997-04-15 HU HU9902640A patent/HUP9902640A3/hu unknown
- 1997-04-15 NZ NZ332256A patent/NZ332256A/xx unknown
- 1997-04-15 DE DE69736597T patent/DE69736597T2/de not_active Expired - Lifetime
- 1997-04-15 BR BR9708959A patent/BR9708959A/pt not_active Application Discontinuation
- 1997-04-15 JP JP9538155A patent/JP2000509271A/ja not_active Ceased
- 1997-04-15 EP EP97921203A patent/EP0909316B1/en not_active Expired - Lifetime
- 1997-04-15 KR KR1019980708430A patent/KR20000010571A/ko active IP Right Grant
- 1997-04-15 CZ CZ983245A patent/CZ324598A3/cs unknown
- 1997-04-15 EA EA199800933A patent/EA002924B1/ru not_active IP Right Cessation
-
1998
- 1998-10-12 NO NO984757A patent/NO984757L/no not_active Application Discontinuation
-
2002
- 2002-05-24 US US10/155,693 patent/US20030175876A1/en not_active Abandoned
-
2006
- 2006-01-12 US US11/332,638 patent/US20060166325A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR9708959A (pt) | 1999-08-03 |
KR20000010571A (ko) | 2000-02-15 |
NO984757L (no) | 1998-12-21 |
ATE338115T1 (de) | 2006-09-15 |
NZ332256A (en) | 2000-03-27 |
AU2730997A (en) | 1997-11-12 |
EP0909316B1 (en) | 2006-08-30 |
US20030175876A1 (en) | 2003-09-18 |
CZ324598A3 (cs) | 1999-01-13 |
CA2250704A1 (en) | 1997-10-30 |
EA002924B1 (ru) | 2002-10-31 |
JP2000509271A (ja) | 2000-07-25 |
WO1997040152A1 (en) | 1997-10-30 |
DE69736597T2 (de) | 2006-12-21 |
ES2271968T3 (es) | 2007-04-16 |
AU720092B2 (en) | 2000-05-25 |
US20060166325A1 (en) | 2006-07-27 |
HUP9902640A2 (hu) | 1999-11-29 |
CA2250704C (en) | 2005-04-12 |
NO984757D0 (no) | 1998-10-12 |
EA199800933A1 (ru) | 1999-04-29 |
US6455277B1 (en) | 2002-09-24 |
SK140398A3 (en) | 1999-04-13 |
DE69736597D1 (de) | 2006-10-12 |
HUP9902640A3 (en) | 2001-11-28 |
EP0909316A1 (en) | 1999-04-21 |
CN1219967A (zh) | 1999-06-16 |
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