IL124677A - Cascade polymer complexes, process for their production and pharmaceutical compositions containing the same - Google Patents

Cascade polymer complexes, process for their production and pharmaceutical compositions containing the same

Info

Publication number
IL124677A
IL124677A IL12467796A IL12467796A IL124677A IL 124677 A IL124677 A IL 124677A IL 12467796 A IL12467796 A IL 12467796A IL 12467796 A IL12467796 A IL 12467796A IL 124677 A IL124677 A IL 124677A
Authority
IL
Israel
Prior art keywords
reproduction
stands
pct
cascade
stand
Prior art date
Application number
IL12467796A
Other languages
English (en)
Other versions
IL124677A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to IL13478696A priority Critical patent/IL134786A/xx
Publication of IL124677A0 publication Critical patent/IL124677A0/xx
Publication of IL124677A publication Critical patent/IL124677A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12467796A 1995-12-22 1996-11-29 Cascade polymer complexes, process for their production and pharmaceutical compositions containing the same IL124677A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL13478696A IL134786A (en) 1995-12-22 1996-11-29 Tetraazacycloalkane derivatives as intermediates for producing cascade polymer complexes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19549286A DE19549286A1 (de) 1995-12-22 1995-12-22 Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
PCT/EP1996/005315 WO1997023245A1 (de) 1995-12-22 1996-11-29 Kaskaden-polymer-komplexe, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
IL124677A0 IL124677A0 (en) 1998-12-06
IL124677A true IL124677A (en) 2005-03-20

Family

ID=7781739

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12467796A IL124677A (en) 1995-12-22 1996-11-29 Cascade polymer complexes, process for their production and pharmaceutical compositions containing the same

Country Status (23)

Country Link
US (1) US6057419A (cs)
EP (1) EP0868202B1 (cs)
JP (1) JP4031041B2 (cs)
KR (1) KR100461476B1 (cs)
AT (1) ATE222776T1 (cs)
BG (1) BG63105B1 (cs)
CA (1) CA2241187A1 (cs)
CZ (1) CZ294238B6 (cs)
DE (2) DE19549286A1 (cs)
DK (1) DK0868202T3 (cs)
ES (1) ES2181924T3 (cs)
IL (1) IL124677A (cs)
MX (1) MX9804860A (cs)
NO (1) NO314545B1 (cs)
NZ (1) NZ323397A (cs)
PL (1) PL187835B1 (cs)
PT (1) PT868202E (cs)
RU (1) RU2197495C2 (cs)
SK (1) SK283334B6 (cs)
TW (1) TW520377B (cs)
UA (1) UA50753C2 (cs)
WO (1) WO1997023245A1 (cs)
ZA (1) ZA9610822B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19652387A1 (de) * 1996-12-04 1998-06-10 Schering Ag Macrocyclische Metallkomplexcarbonsäuren, ihre Verwendung sowie Verfahren zu ihrer Herstellung
DE19728954C1 (de) * 1997-06-30 1999-04-22 Schering Ag Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19744003B4 (de) * 1997-09-26 2004-07-08 Schering Ag Kontrastmittel für das Infarkt- und Nekroseimaging
DE19758105A1 (de) * 1997-12-18 1999-06-24 Schering Ag Dendritische Polymer-Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
US7405320B2 (en) 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
FR2841258A1 (fr) * 2002-06-20 2003-12-26 Pf Medicament Procede et preparation de mononegavirus recombinants et leurs applications
CN101400661A (zh) 2006-03-14 2009-04-01 马林克罗特公司 四氮杂大环衍生物的金属络合物
DE102007002726A1 (de) * 2007-01-18 2008-07-31 Bayer Schering Pharma Aktiengesellschaft Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
WO2014197763A1 (en) * 2013-06-07 2014-12-11 The Board Of Regents Of The University Of Teas System Molecular design toward dual-modality probes for radioisotope-based imaging (pet or spect) and mri
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
ES2814555T3 (es) 2016-11-28 2021-03-29 Bayer Pharma AG Compuestos de quelato de gadolinio con alta relaxividad para usar en la obtención de imágenes por resonancia magnética
CN113164628A (zh) 2018-11-23 2021-07-23 拜耳股份有限公司 造影介质制剂及其制备方法
RU2706705C1 (ru) * 2019-03-28 2019-11-20 Федеральное государственное бюджетное учреждение науки Иркутский институт химии им.А.Е.Фаворского Сибирского отделения Российской академии наук Водорастворимые магнитоактивные нанобиокомпозиты флавоноидных комплексов гадолиния на основе природного конъюгата арабиногалактана с биофлавоноидами и способ получения этих нанобиокомпозитов

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527524A (en) * 1986-08-18 1996-06-18 The Dow Chemical Company Dense star polymer conjugates
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4344460A1 (de) * 1993-12-22 1995-06-29 Schering Ag Metallkomplexe von dendrimeren Makromolekülen, diese enthaltende diagnostische Mittel sowie Verfahren zur Herstellung der Komplexe und Mittel
GB9404208D0 (en) * 1994-03-04 1994-04-20 Nycomed Salutar Inc Chelants
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
DE4425857A1 (de) * 1994-07-07 1996-01-11 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US5919433A (en) * 1996-12-04 1999-07-06 Schering Aktiengesellschaft Macrocyclic metal complex carboxylic acids, their use as well as process for their production

Also Published As

Publication number Publication date
ATE222776T1 (de) 2002-09-15
NO982903L (no) 1998-06-22
NZ323397A (en) 1999-11-29
EP0868202A1 (de) 1998-10-07
PL187835B1 (pl) 2004-10-29
PT868202E (pt) 2003-01-31
BG102565A (en) 1999-06-30
UA50753C2 (uk) 2002-11-15
CZ198198A3 (cs) 1998-09-16
DE19549286A1 (de) 1997-06-26
SK85498A3 (en) 1998-11-04
NO982903D0 (no) 1998-06-22
MX9804860A (es) 1998-10-31
NO314545B1 (no) 2003-04-07
JP2000510880A (ja) 2000-08-22
PL327977A1 (en) 1999-01-04
BG63105B1 (bg) 2001-04-30
JP4031041B2 (ja) 2008-01-09
CZ294238B6 (cs) 2004-11-10
KR19990076638A (ko) 1999-10-15
TW520377B (en) 2003-02-11
IL124677A0 (en) 1998-12-06
DK0868202T3 (da) 2002-12-09
EP0868202B1 (de) 2002-08-28
RU2197495C2 (ru) 2003-01-27
ES2181924T3 (es) 2003-03-01
ZA9610822B (en) 1997-06-27
DE59609603D1 (de) 2002-10-02
US6057419A (en) 2000-05-02
SK283334B6 (sk) 2003-06-03
WO1997023245A1 (de) 1997-07-03
KR100461476B1 (ko) 2005-04-06
CA2241187A1 (en) 1997-07-03

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Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees