DK0868202T3 - Kaskade-polymer-komplekser, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende disse - Google Patents

Kaskade-polymer-komplekser, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende disse

Info

Publication number
DK0868202T3
DK0868202T3 DK96941055T DK96941055T DK0868202T3 DK 0868202 T3 DK0868202 T3 DK 0868202T3 DK 96941055 T DK96941055 T DK 96941055T DK 96941055 T DK96941055 T DK 96941055T DK 0868202 T3 DK0868202 T3 DK 0868202T3
Authority
DK
Denmark
Prior art keywords
cascade
reproduction
stands
pct
stand
Prior art date
Application number
DK96941055T
Other languages
English (en)
Inventor
Heribert Schmitt-Willich
Johannes Platzek
Bernd Raduechel
Hanns-Joachim Weinmann
Wolfgang Ebert
Bernd Misselwitz
Andreas Muehler
Thomas Frenzel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0868202T3 publication Critical patent/DK0868202T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DK96941055T 1995-12-22 1996-11-29 Kaskade-polymer-komplekser, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende disse DK0868202T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19549286A DE19549286A1 (de) 1995-12-22 1995-12-22 Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
PCT/EP1996/005315 WO1997023245A1 (de) 1995-12-22 1996-11-29 Kaskaden-polymer-komplexe, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (1)

Publication Number Publication Date
DK0868202T3 true DK0868202T3 (da) 2002-12-09

Family

ID=7781739

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96941055T DK0868202T3 (da) 1995-12-22 1996-11-29 Kaskade-polymer-komplekser, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende disse

Country Status (23)

Country Link
US (1) US6057419A (da)
EP (1) EP0868202B1 (da)
JP (1) JP4031041B2 (da)
KR (1) KR100461476B1 (da)
AT (1) ATE222776T1 (da)
BG (1) BG63105B1 (da)
CA (1) CA2241187A1 (da)
CZ (1) CZ294238B6 (da)
DE (2) DE19549286A1 (da)
DK (1) DK0868202T3 (da)
ES (1) ES2181924T3 (da)
IL (1) IL124677A (da)
MX (1) MX9804860A (da)
NO (1) NO314545B1 (da)
NZ (1) NZ323397A (da)
PL (1) PL187835B1 (da)
PT (1) PT868202E (da)
RU (1) RU2197495C2 (da)
SK (1) SK283334B6 (da)
TW (1) TW520377B (da)
UA (1) UA50753C2 (da)
WO (1) WO1997023245A1 (da)
ZA (1) ZA9610822B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19652387A1 (de) * 1996-12-04 1998-06-10 Schering Ag Macrocyclische Metallkomplexcarbonsäuren, ihre Verwendung sowie Verfahren zu ihrer Herstellung
DE19728954C1 (de) * 1997-06-30 1999-04-22 Schering Ag Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19744003B4 (de) * 1997-09-26 2004-07-08 Schering Ag Kontrastmittel für das Infarkt- und Nekroseimaging
DE19758105A1 (de) * 1997-12-18 1999-06-24 Schering Ag Dendritische Polymer-Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
US7405320B2 (en) 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
FR2841258A1 (fr) * 2002-06-20 2003-12-26 Pf Medicament Procede et preparation de mononegavirus recombinants et leurs applications
JP5518465B2 (ja) * 2006-03-14 2014-06-11 マリンクロッド エルエルシー テトラアザ大員環誘導体の金属錯体
DE102007002726A1 (de) * 2007-01-18 2008-07-31 Bayer Schering Pharma Aktiengesellschaft Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US9463254B2 (en) 2013-06-07 2016-10-11 The Board Of Regents Of The University Of Texas System Molecular design toward dual-modality probes for radioisotope-based imaging (PET or SPECT) and MRI
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
RU2755181C2 (ru) 2016-11-28 2021-09-14 Байер Фарма Акциенгезельшафт Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации
MX2021006024A (es) 2018-11-23 2021-07-06 Bayer Ag Formulacion de medios de contraste y proceso para prepararlos.
RU2706705C1 (ru) * 2019-03-28 2019-11-20 Федеральное государственное бюджетное учреждение науки Иркутский институт химии им.А.Е.Фаворского Сибирского отделения Российской академии наук Водорастворимые магнитоактивные нанобиокомпозиты флавоноидных комплексов гадолиния на основе природного конъюгата арабиногалактана с биофлавоноидами и способ получения этих нанобиокомпозитов

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527524A (en) * 1986-08-18 1996-06-18 The Dow Chemical Company Dense star polymer conjugates
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4344460A1 (de) * 1993-12-22 1995-06-29 Schering Ag Metallkomplexe von dendrimeren Makromolekülen, diese enthaltende diagnostische Mittel sowie Verfahren zur Herstellung der Komplexe und Mittel
GB9404208D0 (en) * 1994-03-04 1994-04-20 Nycomed Salutar Inc Chelants
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
DE4425857A1 (de) * 1994-07-07 1996-01-11 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US5919433A (en) * 1996-12-04 1999-07-06 Schering Aktiengesellschaft Macrocyclic metal complex carboxylic acids, their use as well as process for their production

Also Published As

Publication number Publication date
JP2000510880A (ja) 2000-08-22
MX9804860A (es) 1998-10-31
NZ323397A (en) 1999-11-29
NO982903D0 (no) 1998-06-22
IL124677A0 (en) 1998-12-06
PT868202E (pt) 2003-01-31
RU2197495C2 (ru) 2003-01-27
TW520377B (en) 2003-02-11
SK85498A3 (en) 1998-11-04
ZA9610822B (en) 1997-06-27
DE59609603D1 (de) 2002-10-02
EP0868202A1 (de) 1998-10-07
NO314545B1 (no) 2003-04-07
EP0868202B1 (de) 2002-08-28
CA2241187A1 (en) 1997-07-03
NO982903L (no) 1998-06-22
BG63105B1 (bg) 2001-04-30
KR19990076638A (ko) 1999-10-15
US6057419A (en) 2000-05-02
ES2181924T3 (es) 2003-03-01
IL124677A (en) 2005-03-20
CZ294238B6 (cs) 2004-11-10
PL327977A1 (en) 1999-01-04
KR100461476B1 (ko) 2005-04-06
DE19549286A1 (de) 1997-06-26
BG102565A (en) 1999-06-30
ATE222776T1 (de) 2002-09-15
CZ198198A3 (cs) 1998-09-16
SK283334B6 (sk) 2003-06-03
JP4031041B2 (ja) 2008-01-09
UA50753C2 (uk) 2002-11-15
PL187835B1 (pl) 2004-10-29
WO1997023245A1 (de) 1997-07-03

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