IL123982A - Multilayer tablets are biologically bound - Google Patents

Multilayer tablets are biologically bound

Info

Publication number
IL123982A
IL123982A IL12398298A IL12398298A IL123982A IL 123982 A IL123982 A IL 123982A IL 12398298 A IL12398298 A IL 12398298A IL 12398298 A IL12398298 A IL 12398298A IL 123982 A IL123982 A IL 123982A
Authority
IL
Israel
Prior art keywords
layer
active principle
bioadhesive
soluble
agent
Prior art date
Application number
IL12398298A
Other languages
English (en)
Hebrew (he)
Original Assignee
Permatec Tech Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Permatec Tech Ag filed Critical Permatec Tech Ag
Publication of IL123982A publication Critical patent/IL123982A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL12398298A 1997-04-23 1998-04-07 Multilayer tablets are biologically bound IL123982A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9705028A FR2762513B1 (fr) 1997-04-23 1997-04-23 Comprimes bioadhesifs

Publications (1)

Publication Number Publication Date
IL123982A true IL123982A (en) 2004-09-27

Family

ID=9506234

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12398298A IL123982A (en) 1997-04-23 1998-04-07 Multilayer tablets are biologically bound

Country Status (16)

Country Link
US (1) US6242004B1 (ko)
EP (1) EP0873750B1 (ko)
JP (1) JPH10298063A (ko)
KR (1) KR100537863B1 (ko)
AR (1) AR012596A1 (ko)
AT (1) ATE268161T1 (ko)
AU (1) AU740421B2 (ko)
CA (1) CA2235520C (ko)
DE (2) DE69824231T2 (ko)
DK (1) DK0873750T3 (ko)
ES (1) ES2125848T3 (ko)
FR (1) FR2762513B1 (ko)
IL (1) IL123982A (ko)
NZ (1) NZ330250A (ko)
PT (1) PT873750E (ko)
ZA (1) ZA983402B (ko)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
EP1095650A1 (en) * 1999-10-29 2001-05-02 Universiteit Leiden Double phase time-controlled release system
JP4993652B2 (ja) * 2004-03-31 2012-08-08 リンテック株式会社 経口投与剤
AU2008201149B2 (en) * 2001-04-24 2010-12-09 Lintec Corporation A gel-forming composition
WO2002087622A1 (fr) * 2001-04-24 2002-11-07 Lintec Corporation Preparations orales et supports pour preparations orales
US8268333B2 (en) * 2001-04-24 2012-09-18 Lintec Corporation Orally administered agent and an orally administered agent/supporting substrate complex
AU2002309238A1 (en) * 2001-06-05 2002-12-16 Barnev Ltd. Birth monitoring system
US20030017195A1 (en) * 2001-07-20 2003-01-23 Samir Mitragotri Method for oral drug delivery
US6585997B2 (en) * 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20030124196A1 (en) * 2001-08-22 2003-07-03 Susan Weinbach Pulsatile release compositions and methods for enhanced intestinal drug absorption
US20030083286A1 (en) * 2001-08-22 2003-05-01 Ching-Leou Teng Bioadhesive compositions and methods for enhanced intestinal drug absorption
DE10211427A1 (de) * 2002-03-15 2003-10-02 Rettenmaier & Soehne Gmbh & Co Zur alsbaldigen Auflösung in Flüssigkeit bestimmter Preßling
DE10252726B4 (de) * 2002-11-13 2008-05-08 Lts Lohmann Therapie-Systeme Ag Mehrschichtiges transmucosales therapeutisches System
US20050038063A1 (en) * 2002-11-29 2005-02-17 Kenneth Newman Method of treating acute pain with unitary dosage form comprising ibuprofen and oxycodone
MXPA05005781A (es) * 2002-11-29 2005-12-12 Forest Laboratories Combinacion de ibuprofeno y oxicodona para alivio de dolor agudo.
ES2209649B1 (es) * 2002-12-09 2005-03-16 Carlos Arana Molina (Titular Al 25%) Utilizacion de la melatonina para la higiene bucodental para uso humano y veterinario como producto activo.
US20040156794A1 (en) * 2003-02-11 2004-08-12 Barkalow David G. Bioerodible and bioadhesive confectionery products and methods of making same
US9358296B2 (en) 2003-02-24 2016-06-07 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US9498454B2 (en) 2003-02-24 2016-11-22 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US9254294B2 (en) 2003-02-24 2016-02-09 Pharmaceutical Productions Inc. Transmucosal hormone delivery system
US7306812B2 (en) 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
JP5137286B2 (ja) * 2003-06-10 2013-02-06 帝國製薬株式会社 フェンタニル含有口腔粘膜貼付剤
US20050249799A1 (en) * 2004-03-03 2005-11-10 Spherics, Inc. Polymeric drug delivery system for hydrophobic drugs
JP2005298471A (ja) * 2004-03-17 2005-10-27 Lintec Corp 薬剤の製造方法
JP2008516893A (ja) * 2004-08-27 2008-05-22 スフェリックス,インク. 多層錠剤および生体接着性剤形
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
BRPI0516732A (pt) * 2004-09-30 2008-09-23 Hershey Co embalagens vedadas de tiras de filme comestìves e métodos para fazer e usar as mesmas
JP2008530250A (ja) * 2005-02-17 2008-08-07 メルク エンド カムパニー インコーポレーテッド アテローム性動脈硬化症、脂質代謝異常及び関連症状の治療方法
WO2007035954A2 (en) * 2005-09-23 2007-03-29 Duramed Pharmaceuticals, Inc. Vaginal tablets comprising misoprostol and methods of making and using the same
AU2007245265A1 (en) * 2006-05-02 2007-11-08 Panacea Biotec Ltd Transmucosal composition
WO2007139661A1 (en) * 2006-05-23 2007-12-06 Haley Jeffrey T Xylitol troches and methods of use
US20100119601A1 (en) 2007-04-11 2010-05-13 Pharmaceutical Productions Inc. Melatonin tablet and methods of preparation and use
WO2009008006A2 (en) * 2007-07-06 2009-01-15 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
EP2942053A1 (en) * 2007-07-06 2015-11-11 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
US9352137B2 (en) * 2008-10-29 2016-05-31 Warsaw Orthopedic, Inc. Drug cartridge for delivering a drug depot comprising a bulking agent and/or cover
US20100106132A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug cartridge for delivering a drug depot comprising superior and inferior covers
US20100106136A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug delivery device with sliding cartridge
US20100106137A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug Delivery System
TWI644689B (zh) * 2013-05-31 2018-12-21 日商久光製藥股份有限公司 Oral patch
US10080877B2 (en) 2014-07-25 2018-09-25 Warsaw Orthopedic, Inc. Drug delivery device and methods having a drug cartridge
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
USD802755S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
JP6830156B2 (ja) 2016-10-31 2021-02-17 ニューリム・ファーマシューティカルズ・リミテッドNeurim Pharmaceuticals Ltd. メラトニンミニタブレットおよびその製造方法
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
JP7260913B2 (ja) * 2017-06-27 2023-04-19 株式会社バイオセレンタック 粘膜付着性経口製剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
JPS5861747A (ja) * 1981-10-08 1983-04-12 馬渕 健一 美容具
CH653550A5 (de) * 1981-10-20 1986-01-15 Sandoz Ag Pharmazeutische zusammensetzung zur verzoegerten freigabe eines medikamentes im mundbereich.
US4573996A (en) 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
JPH0794384B2 (ja) * 1986-09-01 1995-10-11 帝国製薬株式会社 徐放性口腔内用製剤
FR2710265B1 (fr) * 1993-09-22 1995-10-20 Adir Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US5849322A (en) 1995-10-23 1998-12-15 Theratech, Inc. Compositions and methods for buccal delivery of pharmaceutical agents

Also Published As

Publication number Publication date
FR2762513A1 (fr) 1998-10-30
DE873750T1 (de) 1999-05-06
KR19980081606A (ko) 1998-11-25
JPH10298063A (ja) 1998-11-10
DE69824231T2 (de) 2005-06-23
ATE268161T1 (de) 2004-06-15
AU740421B2 (en) 2001-11-01
CA2235520A1 (fr) 1998-10-23
ES2125848T1 (es) 1999-03-16
AU6352398A (en) 1998-10-29
US6242004B1 (en) 2001-06-05
EP0873750A1 (fr) 1998-10-28
FR2762513B1 (fr) 2003-08-22
ZA983402B (en) 1998-10-27
PT873750E (pt) 2004-10-29
AR012596A1 (es) 2000-11-08
EP0873750B1 (fr) 2004-06-02
DK0873750T3 (da) 2004-10-11
KR100537863B1 (ko) 2006-05-03
DE69824231D1 (de) 2004-07-08
NZ330250A (en) 1999-05-28
ES2125848T3 (es) 2005-02-01
CA2235520C (fr) 2007-05-08

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Legal Events

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FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees