ES2125848T1 - Comprimidos bioadhesivos. - Google Patents

Comprimidos bioadhesivos.

Info

Publication number
ES2125848T1
ES2125848T1 ES98400897T ES98400897T ES2125848T1 ES 2125848 T1 ES2125848 T1 ES 2125848T1 ES 98400897 T ES98400897 T ES 98400897T ES 98400897 T ES98400897 T ES 98400897T ES 2125848 T1 ES2125848 T1 ES 2125848T1
Authority
ES
Spain
Prior art keywords
bioadhesive
layer
bioadhesive tablets
total load
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES98400897T
Other languages
English (en)
Other versions
ES2125848T3 (es
Inventor
Isabelle Rault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antares Pharma IPL AG
Original Assignee
Permatec Technologie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Permatec Technologie AG filed Critical Permatec Technologie AG
Publication of ES2125848T1 publication Critical patent/ES2125848T1/es
Application granted granted Critical
Publication of ES2125848T3 publication Critical patent/ES2125848T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Abstract

LA INVENCION SE REFIERE A UNOS COMPUESTOS BIOADHESIVOS QUE SE PRESENTAN EN FORMA DE VARIAS CAPAS Y COMPRENDEN AL MENOS UNA CAPA BIOADHESIVA CON LA CARGA TOTAL DE MATERIAL BIOADHESIVO. ESTA CAPA SE PUEDE COMPRIMIR DIRECTAMENTE DURANTE LA ELABORACION DEL COMPRIMIDO. EL COMPUESTO TIENE ADEMAS AL MENOS UNA CAPA CON LA CARGA TOTAL DE PRINCIPIO ACTIVO.
ES98400897T 1997-04-23 1998-04-10 Comprimidos bioadhesivos. Expired - Lifetime ES2125848T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9705028A FR2762513B1 (fr) 1997-04-23 1997-04-23 Comprimes bioadhesifs
FR9705028 1997-04-23

Publications (2)

Publication Number Publication Date
ES2125848T1 true ES2125848T1 (es) 1999-03-16
ES2125848T3 ES2125848T3 (es) 2005-02-01

Family

ID=9506234

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98400897T Expired - Lifetime ES2125848T3 (es) 1997-04-23 1998-04-10 Comprimidos bioadhesivos.

Country Status (16)

Country Link
US (1) US6242004B1 (es)
EP (1) EP0873750B1 (es)
JP (1) JPH10298063A (es)
KR (1) KR100537863B1 (es)
AR (1) AR012596A1 (es)
AT (1) ATE268161T1 (es)
AU (1) AU740421B2 (es)
CA (1) CA2235520C (es)
DE (2) DE873750T1 (es)
DK (1) DK0873750T3 (es)
ES (1) ES2125848T3 (es)
FR (1) FR2762513B1 (es)
IL (1) IL123982A (es)
NZ (1) NZ330250A (es)
PT (1) PT873750E (es)
ZA (1) ZA983402B (es)

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US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
EP1095650A1 (en) * 1999-10-29 2001-05-02 Universiteit Leiden Double phase time-controlled release system
AU2008201149B2 (en) * 2001-04-24 2010-12-09 Lintec Corporation A gel-forming composition
JP4993652B2 (ja) * 2004-03-31 2012-08-08 リンテック株式会社 経口投与剤
EP1391212A4 (en) * 2001-04-24 2008-09-03 Lintec Corp ORAL PREPARATIONS AND MEDIA FOR ORAL PREPARATIONS
US8268333B2 (en) * 2001-04-24 2012-09-18 Lintec Corporation Orally administered agent and an orally administered agent/supporting substrate complex
WO2002098271A2 (en) * 2001-06-05 2002-12-12 Barnev Ltd. Birth monitoring system
AU2002319653A1 (en) * 2001-07-20 2003-03-03 Samir Mitragotri Method for oral drug delivery
US6585997B2 (en) * 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20030124196A1 (en) * 2001-08-22 2003-07-03 Susan Weinbach Pulsatile release compositions and methods for enhanced intestinal drug absorption
US20030083286A1 (en) * 2001-08-22 2003-05-01 Ching-Leou Teng Bioadhesive compositions and methods for enhanced intestinal drug absorption
DE10211427A1 (de) * 2002-03-15 2003-10-02 Rettenmaier & Soehne Gmbh & Co Zur alsbaldigen Auflösung in Flüssigkeit bestimmter Preßling
DE10252726B4 (de) 2002-11-13 2008-05-08 Lts Lohmann Therapie-Systeme Ag Mehrschichtiges transmucosales therapeutisches System
CA2507851A1 (en) * 2002-11-29 2004-06-17 Forest Laboratories, Inc. Combination of ibuprofen and oxycodone for acute pain relief
US20050038063A1 (en) * 2002-11-29 2005-02-17 Kenneth Newman Method of treating acute pain with unitary dosage form comprising ibuprofen and oxycodone
ES2209649B1 (es) * 2002-12-09 2005-03-16 Carlos Arana Molina (Titular Al 25%) Utilizacion de la melatonina para la higiene bucodental para uso humano y veterinario como producto activo.
US20040156794A1 (en) * 2003-02-11 2004-08-12 Barkalow David G. Bioerodible and bioadhesive confectionery products and methods of making same
US9254294B2 (en) 2003-02-24 2016-02-09 Pharmaceutical Productions Inc. Transmucosal hormone delivery system
US9358296B2 (en) 2003-02-24 2016-06-07 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US9498454B2 (en) 2003-02-24 2016-11-22 Pharmaceutical Productions Inc. Transmucosal drug delivery system
US7306812B2 (en) 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
JP5137286B2 (ja) 2003-06-10 2013-02-06 帝國製薬株式会社 フェンタニル含有口腔粘膜貼付剤
WO2005084639A2 (en) * 2004-03-03 2005-09-15 Spherics, Inc. Polymeric drug delivery system for hydrophobic drugs
JP2005298471A (ja) * 2004-03-17 2005-10-27 Lintec Corp 薬剤の製造方法
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
JP2008516893A (ja) * 2004-08-27 2008-05-22 スフェリックス，インク． 多層錠剤および生体接着性剤形
ATE511359T1 (de) * 2004-09-30 2011-06-15 Hershey Co Versiegelte essbare folienstreifenpakete und verfahren zu ihrer herstellung und verwendung
CN101189011A (zh) * 2005-02-17 2008-05-28 默克公司 治疗动脉粥样硬化、脂质异常和相关状况的方法
US8148560B2 (en) * 2005-09-23 2012-04-03 Teva Women's Health, Inc. Vaginal tablets comprising misoprostol and methods of making and using the same
JP2009535397A (ja) * 2006-05-02 2009-10-01 パナセア バイオテック リミテッド 経粘膜的組成物
ES2565629T3 (es) * 2006-05-23 2016-04-06 Orahealth Corporation Comprimido de adhesión oral bicapa con adhesivo de goma arábiga
MX2009010878A (es) 2007-04-11 2010-03-26 John A Mccarty Pastilla de melatonina y metodos de preparacion y uso.
EP2942053A1 (en) * 2007-07-06 2015-11-11 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
US8974825B2 (en) * 2007-07-06 2015-03-10 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
US20100106132A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug cartridge for delivering a drug depot comprising superior and inferior covers
US20100106137A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug Delivery System
US9352137B2 (en) * 2008-10-29 2016-05-31 Warsaw Orthopedic, Inc. Drug cartridge for delivering a drug depot comprising a bulking agent and/or cover
US20100106136A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug delivery device with sliding cartridge
WO2014192918A1 (ja) * 2013-05-31 2014-12-04 久光製薬株式会社 口腔貼付剤
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
US10080877B2 (en) 2014-07-25 2018-09-25 Warsaw Orthopedic, Inc. Drug delivery device and methods having a drug cartridge
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
USD802757S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
EP3337462B1 (en) * 2016-10-31 2020-09-30 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
WO2019004088A1 (ja) * 2017-06-27 2019-01-03 株式会社バイオセレンタック 粘膜付着性経口製剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
JPS5861747A (ja) * 1981-10-08 1983-04-12 馬渕　健一 美容具
CH653550A5 (de) * 1981-10-20 1986-01-15 Sandoz Ag Pharmazeutische zusammensetzung zur verzoegerten freigabe eines medikamentes im mundbereich.
US4573996A (en) 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
JPH0794384B2 (ja) * 1986-09-01 1995-10-11 帝国製薬株式会社 徐放性口腔内用製剤
FR2710265B1 (fr) * 1993-09-22 1995-10-20 Adir Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US5849322A (en) 1995-10-23 1998-12-15 Theratech, Inc. Compositions and methods for buccal delivery of pharmaceutical agents

Also Published As

Publication number Publication date
EP0873750B1 (fr) 2004-06-02
ATE268161T1 (de) 2004-06-15
FR2762513B1 (fr) 2003-08-22
JPH10298063A (ja) 1998-11-10
DE69824231T2 (de) 2005-06-23
AU6352398A (en) 1998-10-29
IL123982A (en) 2004-09-27
ZA983402B (en) 1998-10-27
KR19980081606A (ko) 1998-11-25
PT873750E (pt) 2004-10-29
NZ330250A (en) 1999-05-28
FR2762513A1 (fr) 1998-10-30
AR012596A1 (es) 2000-11-08
CA2235520A1 (fr) 1998-10-23
EP0873750A1 (fr) 1998-10-28
DE873750T1 (de) 1999-05-06
US6242004B1 (en) 2001-06-05
ES2125848T3 (es) 2005-02-01
CA2235520C (fr) 2007-05-08
DK0873750T3 (da) 2004-10-11
DE69824231D1 (de) 2004-07-08
AU740421B2 (en) 2001-11-01
KR100537863B1 (ko) 2006-05-03

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