ES2060825T3 - Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa. - Google Patents

Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.

Info

Publication number
ES2060825T3
ES2060825T3 ES90102770T ES90102770T ES2060825T3 ES 2060825 T3 ES2060825 T3 ES 2060825T3 ES 90102770 T ES90102770 T ES 90102770T ES 90102770 T ES90102770 T ES 90102770T ES 2060825 T3 ES2060825 T3 ES 2060825T3
Authority
ES
Spain
Prior art keywords
delayed
therapeutic system
percutanea
mucosa
active substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90102770T
Other languages
English (en)
Inventor
Walter Dr Dipl-Chem Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2060825T3 publication Critical patent/ES2060825T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Furan Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Steroid Compounds (AREA)

Abstract

SE HA INVENTADO UN SISTEMA TERAPEUTICO PARA EL SUMINISTRO TRANSDERMAL O TRANSMUCOSAL RETARDADO Y CONTROLADO DE SUSTANCIAS ACTIVADORAS QUE SE COMPONE DE UNA CAPA TRASERA IMPERMEABLE, UN DEPOSITO DE SUSTANCIAS AUXILIARES, UN DEPOSITO DE SUSTANCIAS ACTIVADORAS Y UNA CAPA PROTECTORA DESPRENDIBLE. EL DEPOSITO DE SUSTANCIAS ACTIVADORAS CONTIENE UNA SUSTANCIA EN ESTADO NO BIODISPONIBLE. LA SUSTANCIA AUXILIAR DEL CORRESPONDIENTE DEPOSITO TRANSFORMA LA SUSTANCIA ACTIVADORA HACIENDOLA BIODISPONIBLE. LOS DEPOSITOS DE SUSTANCIAS AUXILIARES Y SUSTANCIAS ACTIVADORAS SE CONECTAN SOLO INMEDIATAMENTE ANTES, O BIEN EN ALGUN MOMENTO DESPUES DE LA APLICACION, DE TAL MANERA QUE LA SUSTANCIA AUXILIAR ENTRE EN EL DEPOSITO DE SUSTANCIAS ACTIVADORAS.
ES90102770T 1989-02-18 1990-02-13 Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa. Expired - Lifetime ES2060825T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3905050A DE3905050A1 (de) 1989-02-18 1989-02-18 Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (ii)

Publications (1)

Publication Number Publication Date
ES2060825T3 true ES2060825T3 (es) 1994-12-01

Family

ID=6374442

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90102770T Expired - Lifetime ES2060825T3 (es) 1989-02-18 1990-02-13 Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.

Country Status (15)

Country Link
US (1) US5466466A (es)
EP (1) EP0384266B1 (es)
JP (1) JP2552190B2 (es)
AT (1) ATE108680T1 (es)
AU (1) AU627268B2 (es)
CA (1) CA2010218C (es)
DD (1) DD291928A5 (es)
DE (2) DE3905050A1 (es)
DK (1) DK0384266T3 (es)
ES (1) ES2060825T3 (es)
FI (1) FI105157B (es)
IE (1) IE66739B1 (es)
NO (1) NO303207B1 (es)
PT (1) PT93191B (es)
ZA (1) ZA901183B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL105073A0 (en) † 1992-03-17 1993-07-08 Becton Dickinson Co User activated iontophoretic device and method for using same
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
DE19653606A1 (de) * 1996-12-20 1998-06-25 Roehm Gmbh Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher
US5912255A (en) * 1998-02-27 1999-06-15 Bussell; Letantia Topical fluoroquinolone antibiotics combined with benzoyl peroxide
DE19814083C2 (de) 1998-03-30 2002-02-07 Lohmann Therapie Syst Lts Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen
DE19814087A1 (de) * 1998-03-30 1999-10-14 Lohmann Therapie Syst Lts Feuchtigkeitsaktivierbares therapeutisches System
ES2240180T3 (es) 1999-10-21 2005-10-16 Alcon Inc. Administracion sub-tenon de medicamentos.
EP1473003B1 (en) 1999-10-21 2008-11-19 Alcon, Inc. Drug delivery device
US6416777B1 (en) 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US20020193321A1 (en) * 2000-12-12 2002-12-19 Mohan Vishnupad Dual dispenser for aesthitically acceptable delivery of anhydrous skin treatment compositions
EP1387671A1 (en) 2001-05-03 2004-02-11 MASSACHUSETTS EYE & EAR INFIRMARY Implantable drug delivery device and use thereof
BR0210287A (pt) * 2001-07-23 2005-12-13 Alcon Inc Dispositivo de administração de droga oftalmológica
MXPA03011609A (es) 2001-07-23 2004-07-01 Alcon Inc Dispositivo de entrega de droga oftalmica.
EP1684669A4 (en) * 2003-07-10 2008-01-02 Alcon Inc DEVICE FOR RELEASING AN OPHTHALMIC MEDICINAL PRODUCT
AU2004285505B2 (en) * 2003-10-28 2010-12-23 Noven Pharmaceuticals, Inc. Transdermal drug delivery device
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
JP5084496B2 (ja) * 2005-02-04 2012-11-28 久光製薬株式会社 経皮吸収貼付剤
CA2616537A1 (en) 2005-07-27 2007-02-01 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
MX2008006379A (es) 2005-11-29 2009-03-03 Smithkline Beecham Corp Metodo de tratamiento.
TWI498136B (zh) * 2007-10-09 2015-09-01 Alcon Res Ltd 用於遞送速率及溫度相依性物質至眼睛的注射器及其製備方法
TWI451862B (zh) * 2007-10-09 2014-09-11 Alcon Res Ltd 用於眼睛注射的熱係數驅動藥丸尺寸
DE102008013701A1 (de) * 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
US8632511B2 (en) 2009-05-06 2014-01-21 Alcon Research, Ltd. Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device
IN2012DN00352A (es) 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
US20120232102A1 (en) 2009-09-30 2012-09-13 Chun-Fang Xu Methods Of Administration And Treatment
US8177747B2 (en) 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
CA2833474C (en) 2011-04-18 2017-09-19 Hisamitsu Pharmaceutical Co., Inc. Method for producing patch, and patch
CN103917093B (zh) 2011-06-14 2017-08-11 比卡姆药品公司 视蛋白结合配体、组合物及使用方法
US9499464B2 (en) 2011-10-19 2016-11-22 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
AU2012346214B2 (en) 2011-11-30 2017-09-14 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
WO2013081642A1 (en) 2011-12-01 2013-06-06 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
EP0249343B1 (en) 1986-06-13 1992-01-08 Alza Corporation Moisture activation of transdermal drug delivery system
EP0249475A3 (en) 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
EP0290262A3 (en) * 1987-05-08 1990-12-12 EASTMAN KODAK COMPANY (a New Jersey corporation) Improved nitrate therapy for angina pectoris
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device

Also Published As

Publication number Publication date
DE59006461D1 (de) 1994-08-25
CA2010218A1 (en) 1990-08-18
FI105157B (fi) 2000-06-30
NO900748L (no) 1990-08-20
DK0384266T3 (da) 1994-11-21
IE66739B1 (en) 1996-02-07
JPH03197420A (ja) 1991-08-28
AU627268B2 (en) 1992-08-20
CA2010218C (en) 1998-04-28
EP0384266A3 (en) 1990-11-22
PT93191B (pt) 1998-01-30
AU4877090A (en) 1990-08-23
EP0384266A2 (de) 1990-08-29
ATE108680T1 (de) 1994-08-15
DD291928A5 (de) 1991-07-18
NO303207B1 (no) 1998-06-15
US5466466A (en) 1995-11-14
JP2552190B2 (ja) 1996-11-06
PT93191A (pt) 1990-08-31
IE900580L (en) 1990-08-18
EP0384266B1 (de) 1994-07-20
DE3905050C2 (es) 1991-08-08
FI900740A0 (fi) 1990-02-14
ZA901183B (en) 1990-11-28
DE3905050A1 (de) 1990-08-30
NO900748D0 (no) 1990-02-16

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