PT93191A - Sistema terapeutico para a administracao retardada e controlada transdermica ou transmucosica de substancias activas - Google Patents
Sistema terapeutico para a administracao retardada e controlada transdermica ou transmucosica de substancias activasInfo
- Publication number
- PT93191A PT93191A PT93191A PT9319190A PT93191A PT 93191 A PT93191 A PT 93191A PT 93191 A PT93191 A PT 93191A PT 9319190 A PT9319190 A PT 9319190A PT 93191 A PT93191 A PT 93191A
- Authority
- PT
- Portugal
- Prior art keywords
- active substance
- substance reservoir
- therapeutic system
- reservoir
- controlled
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 8
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 5
- 239000010410 layer Substances 0.000 abstract 1
- 239000011241 protective layer Substances 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3905050A DE3905050A1 (de) | 1989-02-18 | 1989-02-18 | Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (ii) |
Publications (2)
Publication Number | Publication Date |
---|---|
PT93191A true PT93191A (pt) | 1990-08-31 |
PT93191B PT93191B (pt) | 1998-01-30 |
Family
ID=6374442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT93191A PT93191B (pt) | 1989-02-18 | 1990-02-16 | Sistema terapeutico para a administracao retardada e controlada transdermica ou transmucosica de substancias activas |
Country Status (15)
Country | Link |
---|---|
US (1) | US5466466A (pt) |
EP (1) | EP0384266B1 (pt) |
JP (1) | JP2552190B2 (pt) |
AT (1) | ATE108680T1 (pt) |
AU (1) | AU627268B2 (pt) |
CA (1) | CA2010218C (pt) |
DD (1) | DD291928A5 (pt) |
DE (2) | DE3905050A1 (pt) |
DK (1) | DK0384266T3 (pt) |
ES (1) | ES2060825T3 (pt) |
FI (1) | FI105157B (pt) |
IE (1) | IE66739B1 (pt) |
NO (1) | NO303207B1 (pt) |
PT (1) | PT93191B (pt) |
ZA (1) | ZA901183B (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT65957A (en) † | 1992-03-17 | 1994-08-29 | Becton Dickinson Co | User operated iontophoretical device and method for manufacturing it |
US5730721A (en) | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
DE19653606A1 (de) * | 1996-12-20 | 1998-06-25 | Roehm Gmbh | Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher |
US5912255A (en) * | 1998-02-27 | 1999-06-15 | Bussell; Letantia | Topical fluoroquinolone antibiotics combined with benzoyl peroxide |
DE19814087A1 (de) | 1998-03-30 | 1999-10-14 | Lohmann Therapie Syst Lts | Feuchtigkeitsaktivierbares therapeutisches System |
DE19814083C2 (de) | 1998-03-30 | 2002-02-07 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen |
CN1292721C (zh) * | 1999-10-21 | 2007-01-03 | 爱尔康公司 | 药物释放装置 |
PT1221918E (pt) | 1999-10-21 | 2005-06-30 | Alcon Inc | Administracao de drogas sub-tenon |
US7943162B2 (en) * | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
US7060732B2 (en) * | 2000-12-12 | 2006-06-13 | Imaginative Research Associates, Inc. | Antibiotic/benzoyl peroxide dispenser |
US20020193321A1 (en) * | 2000-12-12 | 2002-12-19 | Mohan Vishnupad | Dual dispenser for aesthitically acceptable delivery of anhydrous skin treatment compositions |
US20060189552A1 (en) * | 2000-12-12 | 2006-08-24 | Mohan Vishnupad | Dispenser for dispensing three or more actives |
WO2002089767A1 (en) | 2001-05-03 | 2002-11-14 | Massachusetts Eye And Ear Infirmary | Implantable drug delivery device and use thereof |
CN1203814C (zh) | 2001-07-23 | 2005-06-01 | 爱尔康公司 | 眼部药物输送装置 |
WO2003009784A1 (en) * | 2001-07-23 | 2003-02-06 | Alcon, Inc. | Ophthalmic drug delivery device |
CA2522592A1 (en) * | 2003-07-10 | 2005-02-03 | Alcon, Inc. | Ophthalmic drug delivery device |
RU2356580C2 (ru) * | 2003-10-28 | 2009-05-27 | Новен Фармасьютикалз, Инк | Композиции и способы, обеспечивающие контролируемую потерю лекарственных средств и доставку в системах трансдермальной доставки лекарственных средств |
US7662855B2 (en) * | 2004-05-11 | 2010-02-16 | Imaginative Research Associates, Inc. | Retinoid solutions and formulations made therefrom |
US20060014834A1 (en) * | 2004-05-11 | 2006-01-19 | Mohan Vishnupad | Retinoid solutions and formulations made therefrom |
DE102004062614B4 (de) * | 2004-12-24 | 2011-12-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung |
US20080138388A1 (en) * | 2005-02-04 | 2008-06-12 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal Absorption Patch |
BRPI0615962A2 (pt) | 2005-07-27 | 2011-05-31 | Univ Florida | uso de um composto selecionado do grupo que consiste em um inibidor proteassomal, um inibidor de autofagia, um inibidor lisossomal, um inibidor do trasporte de proteìna do er ao golgi, um inibidor de chaperonina hsp90, um ativador da resposta a choque térmico, um inibidor de glicosidade, e um inibidor de histona deacetilase, uso de 11-cis-retinal ou 9-cis-retinal e um composto selecionado do grupo que consiste em um inibidor proteassomal, um inibidor de autofagia, um inibidor lissosomal, um inibidor do transporte de proteìna do er ao golgi, um inibidor de chaperonina hsp90, um ativador de resposta a choque térmico, um inibidor de glicosidase, e um inibidor de histona deacetilase, método para aumentar a quantidade de um conformação bioquimicamente funcional de uma proteìna em uma célula, composição farmacêutica para o tratamento de um pcd ocular, composição farmacêutica para o tratamento de retinite pigmentosa, kit para o tratamento de um pcd ocular, kit para o tratamento de retinite pigmentosa, método para a identificação de um composto útil para o tratamento de um indivìduo que tem um pcd ocular, método para a identificação de um composto útil para o tratamento de um indivìduo que tem retinite pigmentosa, uso de um inibidor proteassomal ou um inibidor de autofagia e método para a produção de uma proteìna recombinante em uma conformação bioquimicamente funcional |
EA016227B1 (ru) | 2005-11-29 | 2012-03-30 | Смитклайн Бичем Корпорейшн | Способ лечения офтальмологических неоваскулярных расстройств |
TWI498136B (zh) * | 2007-10-09 | 2015-09-01 | Alcon Res Ltd | 用於遞送速率及溫度相依性物質至眼睛的注射器及其製備方法 |
TWI451862B (zh) * | 2007-10-09 | 2014-09-11 | Alcon Res Ltd | 用於眼睛注射的熱係數驅動藥丸尺寸 |
DE102008013701A1 (de) * | 2008-03-11 | 2009-09-17 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit stabilisierter Membran |
US8632511B2 (en) | 2009-05-06 | 2014-01-21 | Alcon Research, Ltd. | Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device |
IN2012DN00352A (pt) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
WO2011039648A1 (en) | 2009-09-30 | 2011-04-07 | Glaxo Wellcome Manufacturing Pte Ltd. | Methods of administration and treatment |
US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
EP2700401B1 (en) | 2011-04-18 | 2020-01-15 | Hisamitsu Pharmaceutical Co., Inc. | Method for producing adhesive patch, and adhesive patch |
US9133082B2 (en) | 2011-06-14 | 2015-09-15 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
US9499464B2 (en) | 2011-10-19 | 2016-11-22 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
EP2785346A4 (en) | 2011-11-30 | 2015-04-29 | Bikam Pharmaceuticals Inc | OPSINBINDING LIGANDS, COMPOSITIONS THEREOF, AND METHOD OF USE THEREOF |
AU2012346537A1 (en) | 2011-12-01 | 2014-07-17 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4405616A (en) | 1975-06-19 | 1983-09-20 | Nelson Research & Development Company | Penetration enhancers for transdermal drug delivery of systemic agents |
US4756710A (en) * | 1985-04-05 | 1988-07-12 | Merck & Co., Inc. | pH-Mediated drug delivery system |
EP0249475A3 (en) | 1986-06-13 | 1989-10-11 | Alza Corporation | Delayed percutaneous delivery |
ES2028074T3 (es) | 1986-06-13 | 1992-07-01 | Alza Corporation | Activacion por humedad de un sistema de suministro transdermico de farmacos. |
EP0290262A3 (en) * | 1987-05-08 | 1990-12-12 | EASTMAN KODAK COMPANY (a New Jersey corporation) | Improved nitrate therapy for angina pectoris |
US4781924A (en) * | 1987-11-09 | 1988-11-01 | Alza Corporation | Transdermal drug delivery device |
-
1989
- 1989-02-18 DE DE3905050A patent/DE3905050A1/de active Granted
-
1990
- 1990-01-25 AU AU48770/90A patent/AU627268B2/en not_active Ceased
- 1990-02-13 ES ES90102770T patent/ES2060825T3/es not_active Expired - Lifetime
- 1990-02-13 DE DE59006461T patent/DE59006461D1/de not_active Expired - Fee Related
- 1990-02-13 EP EP90102770A patent/EP0384266B1/de not_active Expired - Lifetime
- 1990-02-13 AT AT90102770T patent/ATE108680T1/de active
- 1990-02-13 DK DK90102770.6T patent/DK0384266T3/da active
- 1990-02-14 FI FI900740A patent/FI105157B/fi not_active IP Right Cessation
- 1990-02-14 JP JP2031657A patent/JP2552190B2/ja not_active Expired - Lifetime
- 1990-02-16 IE IE58090A patent/IE66739B1/en not_active IP Right Cessation
- 1990-02-16 ZA ZA901183A patent/ZA901183B/xx unknown
- 1990-02-16 DD DD90337919A patent/DD291928A5/de not_active IP Right Cessation
- 1990-02-16 CA CA002010218A patent/CA2010218C/en not_active Expired - Fee Related
- 1990-02-16 NO NO900748A patent/NO303207B1/no not_active IP Right Cessation
- 1990-02-16 PT PT93191A patent/PT93191B/pt active IP Right Grant
-
1994
- 1994-04-20 US US08/230,448 patent/US5466466A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE59006461D1 (de) | 1994-08-25 |
ATE108680T1 (de) | 1994-08-15 |
EP0384266A3 (en) | 1990-11-22 |
PT93191B (pt) | 1998-01-30 |
EP0384266B1 (de) | 1994-07-20 |
DK0384266T3 (da) | 1994-11-21 |
DD291928A5 (de) | 1991-07-18 |
IE900580L (en) | 1990-08-18 |
JPH03197420A (ja) | 1991-08-28 |
IE66739B1 (en) | 1996-02-07 |
NO303207B1 (no) | 1998-06-15 |
ZA901183B (en) | 1990-11-28 |
DE3905050A1 (de) | 1990-08-30 |
AU627268B2 (en) | 1992-08-20 |
JP2552190B2 (ja) | 1996-11-06 |
EP0384266A2 (de) | 1990-08-29 |
CA2010218A1 (en) | 1990-08-18 |
CA2010218C (en) | 1998-04-28 |
AU4877090A (en) | 1990-08-23 |
FI105157B (fi) | 2000-06-30 |
ES2060825T3 (es) | 1994-12-01 |
FI900740A0 (fi) | 1990-02-14 |
NO900748L (no) | 1990-08-20 |
US5466466A (en) | 1995-11-14 |
NO900748D0 (no) | 1990-02-16 |
DE3905050C2 (pt) | 1991-08-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19971024 |