MX2009010878A - Pastilla de melatonina y metodos de preparacion y uso. - Google Patents

Pastilla de melatonina y metodos de preparacion y uso.

Info

Publication number
MX2009010878A
MX2009010878A MX2009010878A MX2009010878A MX2009010878A MX 2009010878 A MX2009010878 A MX 2009010878A MX 2009010878 A MX2009010878 A MX 2009010878A MX 2009010878 A MX2009010878 A MX 2009010878A MX 2009010878 A MX2009010878 A MX 2009010878A
Authority
MX
Mexico
Prior art keywords
methods
preparation
pharmaceutically acceptable
pharmaceutical composition
melatonin
Prior art date
Application number
MX2009010878A
Other languages
English (en)
Inventor
John A Mccarty
Original Assignee
John A Mccarty
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John A Mccarty filed Critical John A Mccarty
Publication of MX2009010878A publication Critical patent/MX2009010878A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Anesthesiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona una composición farmacéutica para administración sublingual o bucal de activos con solubilidad acuosa baja a pobre, por ejemplo, la melatonina de la hormona de indol, la cual contiene una solución del ingrediente activo en un solvente farmacéuticamente aceptable adsorbido o absorbido en las partículas de un portador farmacéuticamente aceptable y método de preparación y uso de la composición farmacéutica.
MX2009010878A 2007-04-11 2008-04-10 Pastilla de melatonina y metodos de preparacion y uso. MX2009010878A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92292107P 2007-04-11 2007-04-11
PCT/US2008/004615 WO2008127609A1 (en) 2007-04-11 2008-04-10 Melatonin tablet and methods of preparation and use

Publications (1)

Publication Number Publication Date
MX2009010878A true MX2009010878A (es) 2010-03-26

Family

ID=39864239

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009010878A MX2009010878A (es) 2007-04-11 2008-04-10 Pastilla de melatonina y metodos de preparacion y uso.

Country Status (11)

Country Link
US (3) US20100119601A1 (es)
EP (2) EP3056220A1 (es)
JP (2) JP5600058B2 (es)
CN (1) CN101677994B (es)
AU (1) AU2008239683B2 (es)
CA (1) CA2683436C (es)
ES (1) ES2575549T3 (es)
IL (2) IL201383A (es)
MX (1) MX2009010878A (es)
RU (1) RU2485949C2 (es)
WO (1) WO2008127609A1 (es)

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US10172810B2 (en) * 2003-02-24 2019-01-08 Pharmaceutical Productions, Inc. Transmucosal ketamine delivery composition
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TR200907338A1 (tr) * 2009-09-28 2011-04-21 Yedi̇tepe Üni̇versi̇tesi̇ Doğal bileşenler içeren bir film şeridi.
AR084865A1 (es) 2011-01-17 2013-07-10 Takeda Pharmaceutical Preparacion de desintegracion rapida, comprimido dispersable por via oral
WO2012103411A2 (en) 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
TR201808978T4 (tr) 2011-02-11 2018-07-23 Zx Pharma Llc Çok partiküllü l-mentol formülasyonları ve ilgili yöntemler.
EP2570126B1 (en) 2011-09-16 2014-03-26 Darius Rassoulian Use of melatonin for treating acute alcohol intoxication
ITMI20112042A1 (it) * 2011-11-10 2013-05-11 Eratech S R L Polvere da ricostituire prima dell'uso comprendente melatonina e preparazione iniettabile ottenibile da tale polvere.
RU2488388C1 (ru) 2012-05-24 2013-07-27 Ооо "Валента Интеллект" Фармацевтическая композиция для профилактики и лечения психических, поведенческих, когнитивных расстройств
UA107653U (uk) 2012-10-01 2016-06-24 Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" Композиція лікарських засобів для лікування та профілактики поведінкових, психічних та когнітивних розладів
EP2919903B1 (en) 2012-11-14 2020-07-22 W.R. Grace & CO. - CONN. Compositions containing a biologically active material and a non-ordered inorganic oxide
US20140303128A1 (en) * 2013-03-14 2014-10-09 Pharmaceutical Productions Inc. Transmucosal hormone delivery system
WO2014175917A1 (en) 2013-04-23 2014-10-30 Zx Pharma, Llc Multiparticulate-menthol formulations and related methods
CA2992923C (en) * 2014-07-21 2021-06-29 Pharmaceutical Productions, Inc. Solid dosage form composition for buccal and sublingual administration of cannabinoids
CN105663061A (zh) * 2014-11-16 2016-06-15 刘佳迪 褪黑素滴丸的制法和用法
NL2015272B1 (en) * 2015-08-05 2017-05-02 Versailles B V Melatonin formulations and methods for preparation and use.
WO2018167273A1 (en) * 2017-03-16 2018-09-20 Repoceuticals Aps Compositions for retarding the decomposition of melatonin in solution
US10806789B2 (en) * 2017-05-12 2020-10-20 The LIV Group Inc. Composition for enhanced absorption of supplements
US10500280B2 (en) 2017-06-20 2019-12-10 Physician's Seal, LLC Orally dissolving melatonin formulation with acidifying agent that renders melatonin soluble in saliva
WO2019038586A1 (en) 2017-08-19 2019-02-28 Ftf Pharma Private Limited PHARMACEUTICAL COMPOSITION OF MELATONIN
CN109953953B (zh) * 2017-12-22 2021-09-21 深圳大学 一种褪黑素纳米缓释给药系统的制备方法
US20200078307A1 (en) 2018-03-11 2020-03-12 Nanologica Ab Porous silica particles for use in a compressed pharmaceutical dosage form
KR102506059B1 (ko) * 2020-10-20 2023-03-07 코스맥스 주식회사 멜라토닌을 포함하는 항산화용 화장료 조성물
CN112426408B (zh) * 2020-12-08 2023-12-19 广州帝奇医药技术有限公司 一种褪黑素组合物及其制备工艺
CN112870193B (zh) * 2021-03-11 2022-07-08 大连医科大学附属第二医院 褪黑素在制备治疗对靶向药物耐药的her2阳性乳腺癌的药物中的应用
WO2023210811A1 (ja) * 2022-04-28 2023-11-02 日本たばこ産業株式会社 無機多孔質材料を含む口腔用組成物
WO2023210813A1 (ja) * 2022-04-28 2023-11-02 日本たばこ産業株式会社 無機多孔質材料を含む口腔用組成物
WO2023210814A1 (ja) * 2022-04-28 2023-11-02 日本たばこ産業株式会社 無機多孔質材料を含む口腔用組成物
WO2023210812A1 (ja) * 2022-04-28 2023-11-02 日本たばこ産業株式会社 多孔質材料を含む口腔用組成物

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Also Published As

Publication number Publication date
US20100119601A1 (en) 2010-05-13
IL201383A0 (en) 2010-05-31
JP2014237700A (ja) 2014-12-18
CA2683436A1 (en) 2008-10-23
US9381190B2 (en) 2016-07-05
IL249102A0 (en) 2017-01-31
IL201383A (en) 2017-01-31
CN101677994A (zh) 2010-03-24
AU2008239683B2 (en) 2014-03-27
US20150174101A1 (en) 2015-06-25
EP3056220A1 (en) 2016-08-17
CA2683436C (en) 2016-07-26
EP2144610A1 (en) 2010-01-20
EP2144610A4 (en) 2013-08-07
EP2144610B1 (en) 2016-04-06
JP2010523673A (ja) 2010-07-15
JP5600058B2 (ja) 2014-10-01
US20130028943A1 (en) 2013-01-31
AU2008239683A1 (en) 2008-10-23
CN101677994B (zh) 2015-07-22
RU2485949C2 (ru) 2013-06-27
ES2575549T3 (es) 2016-06-29
WO2008127609A1 (en) 2008-10-23
US8992948B2 (en) 2015-03-31
RU2009137472A (ru) 2011-05-20

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Owner name: PHARMACEUTICAL PRODUCTIONS, INC.

FG Grant or registration