IL123848A - Tobramycin aerosol formulation for treatment and prevention of pulmonary diseases caused by mycobacterium tuberculosis and/or mycobacterium bovis - Google Patents

Tobramycin aerosol formulation for treatment and prevention of pulmonary diseases caused by mycobacterium tuberculosis and/or mycobacterium bovis

Info

Publication number
IL123848A
IL123848A IL12384898A IL12384898A IL123848A IL 123848 A IL123848 A IL 123848A IL 12384898 A IL12384898 A IL 12384898A IL 12384898 A IL12384898 A IL 12384898A IL 123848 A IL123848 A IL 123848A
Authority
IL
Israel
Prior art keywords
tobramycin
formulation
tuberculosis
aerosol
nebulizer
Prior art date
Application number
IL12384898A
Other languages
English (en)
Other versions
IL123848A0 (en
Original Assignee
Pathogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pathogenesis Inc filed Critical Pathogenesis Inc
Publication of IL123848A0 publication Critical patent/IL123848A0/xx
Publication of IL123848A publication Critical patent/IL123848A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12384898A 1997-04-02 1998-03-26 Tobramycin aerosol formulation for treatment and prevention of pulmonary diseases caused by mycobacterium tuberculosis and/or mycobacterium bovis IL123848A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/825,725 US6083922A (en) 1996-04-02 1997-04-02 Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis

Publications (2)

Publication Number Publication Date
IL123848A0 IL123848A0 (en) 1998-10-30
IL123848A true IL123848A (en) 2002-12-01

Family

ID=25244769

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12384898A IL123848A (en) 1997-04-02 1998-03-26 Tobramycin aerosol formulation for treatment and prevention of pulmonary diseases caused by mycobacterium tuberculosis and/or mycobacterium bovis

Country Status (7)

Country Link
US (1) US6083922A (fr)
AR (1) AR011706A1 (fr)
AU (1) AU6469198A (fr)
BR (1) BR9801008A (fr)
IL (1) IL123848A (fr)
WO (1) WO1998043650A1 (fr)
ZA (1) ZA982447B (fr)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
WO2002072169A2 (fr) * 2001-03-09 2002-09-19 Antares Pharma, Inc. Nubuliseur oculaire d'administration de medicaments
EP1598059A1 (fr) * 2001-05-18 2005-11-23 Chiron Corporation Méthodes et formulations en doses unitaires pour l'administration d'aminoglycosides par inhalation
AU2007202942B2 (en) * 2001-05-18 2010-05-27 Novartis Ag Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics
ES2261735T3 (es) 2001-05-18 2006-11-16 Chiron Corporation Sistema para la administracion de una formulacion de tobramicina.
WO2003037365A1 (fr) * 2001-11-01 2003-05-08 The Johns Hopkins University Procedes et compositions pour traiter la fuite vasculaire au moyen du facteur de croissance hepacytotaire
EP1531795A4 (fr) 2002-05-02 2011-02-23 Harvard College Formulations limitant l'extension d'infections pulmonaires
US20050220720A1 (en) * 2002-05-02 2005-10-06 David Edwards Formulations limiting spread of pulmonary infections
US7607436B2 (en) * 2002-05-06 2009-10-27 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
US8245708B2 (en) * 2002-05-07 2012-08-21 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
DE602004031829D1 (de) 2003-05-20 2011-04-28 Collins Ophthalmisches arzneimittelabgabesystem
US8545463B2 (en) 2003-05-20 2013-10-01 Optimyst Systems Inc. Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device
CA2541849C (fr) * 2003-10-15 2012-07-31 Pari Gmbh Preparation liquide contenant de la tobramycine
US20050207983A1 (en) * 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
DK1750667T3 (da) 2004-05-17 2011-04-26 Corus Pharma Inc Kombination af fosfomycin/aminoglycosid i aerosolform til behandling af bakterielle luftvejsinfektioner
US8627821B2 (en) * 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
EP1888257A1 (fr) * 2005-05-05 2008-02-20 Pulmatrix, Inc. Generateur d'aerosols a ultra-sons
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
AU2006247077A1 (en) * 2005-05-18 2006-11-23 Pulmatrix Inc. Formulations for alteration of biophysical properties of mucosal lining
WO2006125132A2 (fr) 2005-05-18 2006-11-23 Mpex Pharmaceuticals, Inc. Fluoroquinolones en aerosols et leurs utilisations
CN104586868A (zh) 2005-09-29 2015-05-06 尼克塔治疗公司 抗生素制剂、单位剂量、试剂盒以及方法
US9539303B2 (en) 2006-04-24 2017-01-10 Celgene Corporation Treatment of Ras-expressing tumors
WO2007146730A2 (fr) 2006-06-08 2007-12-21 Gloucester Pharmaceuticals Thérapie à base d'inhibiteurs de désacétylase (dac)
AU2007296744A1 (en) 2006-09-11 2008-03-20 Curis, Inc. Multi-functional small molecules as anti-proliferative agents
JP2008199905A (ja) * 2007-02-16 2008-09-04 Snow Brand Milk Prod Co Ltd 乳酸菌生残性向上剤
EP2346509B1 (fr) 2008-10-07 2020-05-13 Horizon Orphan LLC Inhalation de lévofloxacine pour réduire une inflammation des poumons
US8815838B2 (en) 2008-10-07 2014-08-26 David C. Griffith Aerosol fluoroquinolone formulations for improved pharmacokinetics
KR20130130875A (ko) 2009-02-27 2013-12-02 이난타 파마슈티칼스, 인코포레이티드 C형 간염 바이러스 억제제
SI2445502T1 (sl) 2009-06-25 2017-10-30 Alkermes Pharma Ireland Limited Heterociklične spojine za zdravljenje neuroloških in psiholoških motenj
US20110014273A1 (en) * 2009-07-15 2011-01-20 Helmut Brunar Method of Treating BCC
NZ598484A (en) 2009-09-04 2014-02-28 Mpex Pharmaceuticals Inc Use of aerosolized levofloxacin for treating cystic fibrosis
ES2647361T3 (es) 2010-01-07 2017-12-21 Alkermes Pharma Ireland Limited Profármacos de sales de amonio cuaternario
WO2011163594A2 (fr) 2010-06-24 2011-12-29 Alkermes, Inc. Promédicaments de composés nh-acides : dérivés esters, carbonates, carbamates et phosphonates
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
CN103118643B (zh) 2010-07-15 2015-06-10 艾诺维亚股份有限公司 用于执行远程治疗和监测的方法和系统
JP5964826B2 (ja) 2010-07-15 2016-08-03 アイノビア,インコーポレイティド 滴生成デバイス
EP2485691B1 (fr) 2010-07-15 2020-03-18 Eyenovia, Inc. Administration de médicament ophtalmique
WO2012030647A1 (fr) 2010-08-30 2012-03-08 Pulmatrix, Inc. Méthodes de traitement de la mucoviscidose
CA2809666C (fr) 2010-08-30 2020-09-22 Michael M. Lipp Formulations de poudre seche et methodes de traitement de maladies pulmonaires
ES2899621T3 (es) 2010-09-29 2022-03-14 Pulmatrix Operating Co Inc Polvos secos catiónicos que comprenden sal de magnesio
CN107096014B (zh) 2010-09-29 2022-07-15 普马特里克斯营业公司 吸入用单价金属阳离子干粉剂
ES2661574T3 (es) 2010-12-23 2018-04-02 Alkermes Pharma Ireland Limited Profármacos de carga de múltiples PAF
TWI574687B (zh) 2011-01-03 2017-03-21 古利斯股份有限公司 具有鋅結合部份之刺蝟拮抗劑
JP6021117B2 (ja) 2011-01-31 2016-11-02 ジェノア ファーマシューティカルズ,インク. エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用
SI2694075T1 (sl) 2011-04-01 2016-07-29 Curis, Inc. Fosfoinozitid 3-kinazni inhibitor z delom, ki veže cink
WO2013090459A1 (fr) 2011-12-12 2013-06-20 Corinthian Ophthalmic, Inc. Mécanisme éjecteur, dispositif éjecteur et procédés d'utilisation
AU2012351747B2 (en) 2011-12-15 2016-05-12 Alkermes Pharma Ireland Limited Prodrugs of secondary amine compounds
HUE044957T2 (hu) 2011-12-15 2019-11-28 Alkermes Pharma Ireland Ltd Samidorphan (ALKS 33) opioid agonistákkal alkotott kombinációja
WO2013130767A1 (fr) 2012-02-29 2013-09-06 Pulmatrix, Inc. Poudres sèches pouvant être inhalées
JP6501264B2 (ja) 2012-07-24 2019-04-17 アヴァリン ファーマ インク. エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
US20140371238A1 (en) 2013-03-13 2014-12-18 Flatley Discovery Lab Compounds and methods for the treatment of cystic fibrosis
MX2015013845A (es) 2013-04-01 2016-05-09 Pulmatrix Inc Polvos secos de tiotropio.
JP6799201B2 (ja) 2013-07-31 2020-12-16 アヴァリン ファーマ インク. エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用
EP3125936B1 (fr) 2014-03-31 2019-05-08 Debiopharm International SA Fusions de fgfr
EP4112071A1 (fr) 2014-08-26 2023-01-04 HSF Pharmaceuticals Nouveaux agents d'immunisation et procédés d'utilisation associés
AU2015328307B2 (en) 2014-10-06 2019-11-21 Apm Therapeutics 1, Inc. Triazolopyridine compounds and methods for the treatment of cystic fibrosis
KR102398439B1 (ko) 2016-03-07 2022-05-16 이난타 파마슈티칼스, 인코포레이티드 B형 간염 항바이러스제
US11597708B2 (en) 2016-09-16 2023-03-07 Hsf Pharmaceuticals Sa Inhibitors of heat shock factors and uses thereof
CN115300226A (zh) 2017-06-10 2022-11-08 艾诺维亚股份有限公司 用于将一体积的流体输送到眼睛的设备
WO2019110099A1 (fr) 2017-12-06 2019-06-13 Qrumpharma Inc. Formulation de clofazimine inhalable
WO2019170871A1 (fr) 2018-03-08 2019-09-12 Hsf Pharmaceuticals Activation localisée de vaccins de rappel vectorisés par le virus de l'herpès à réplication de virus
BR112020022633A2 (pt) 2018-05-10 2021-05-04 Cis Pharma Ag copolímero biocompatível contendo moléculas de agente ativo múltiplas
EP3840737A1 (fr) 2018-08-23 2021-06-30 MannKind Corporation Compositions de clofazimine, combinaisons les comprenant, leurs procédés de préparation, utilisations et procédés les comprenant
UY38383A (es) 2018-09-21 2020-04-30 Enanta Pharm Inc Heterociclos funcionalizados como agentes antivirales
EP3653716A1 (fr) 2018-11-19 2020-05-20 HSF Pharmaceuticals Vecteurs de virus alpha-herpès contrôlés de réplication et leurs utilisations
EP3980373A1 (fr) 2019-06-04 2022-04-13 Thirty Holdings Limited Méthodes et compositions pour générer de l'oxyde nitrique et utilisations associées
US20220257642A1 (en) 2019-06-04 2022-08-18 Thirty Respiratory Limited Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
KR20220092565A (ko) 2019-10-30 2022-07-01 씨아이에스 파르마 에이쥐 활성제를 전달하기 위한 생체 적합성 중합체 약물 담체
WO2021214440A1 (fr) 2020-04-23 2021-10-28 Thirty Respiratory Limited Oxyde nitrique ou compositions libérant de l'oxyde nitrique destinés à être utilisés dans le traitement du sars-cov et du sars-cov-2
EP4138794A1 (fr) 2020-04-23 2023-03-01 Thirty Respiratory Limited Procédés et compositions pour le traitement et la lutte contre la tuberculose
WO2021214279A1 (fr) 2020-04-24 2021-10-28 Hsf Pharmaceuticals Virus de l'herpès contrôlé capable de se répliquer exprimant un antigène du sars-cov-2
EP4157237A2 (fr) 2020-06-01 2023-04-05 Advent Therapeutics Inc. Compositions pharmaceutiques comprenant des principes actifs insolubles
WO2021262799A1 (fr) 2020-06-23 2021-12-30 Flagship Pioneering, Inc. Composés antiviraux et leurs procédés d'utilisation
ES2922973T1 (es) 2020-07-20 2022-09-22 Enanta Pharm Inc Peptidos funcionalizados como agentes antivirales
KR20230124582A (ko) 2020-11-23 2023-08-25 이난타 파마슈티칼스, 인코포레이티드 신규한 스피로피롤리딘 유래 항바이러스제
WO2022240897A1 (fr) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Composition pharmaceutique comprenant de la délafloxacine destinée à être administrée dans le poumon
WO2023006993A1 (fr) 2021-07-30 2023-02-02 Atmosr Dérivés d'amino pyridine ou pyrimidine condensée pour le traitement du syndrome d'hypoventilation centrale congénitale
WO2023028364A1 (fr) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Compositions ciblées et leurs utilisations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739046A (en) * 1985-08-19 1988-04-19 Luzio Nicholas R Di Soluble phosphorylated glucan
US5006343A (en) * 1988-12-29 1991-04-09 Benson Bradley J Pulmonary administration of pharmaceutically active substances
US5284133A (en) * 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5508269A (en) * 1994-10-19 1996-04-16 Pathogenesis Corporation Aminoglycoside formulation for aerosolization

Also Published As

Publication number Publication date
IL123848A0 (en) 1998-10-30
AU6469198A (en) 1998-10-22
AR011706A1 (es) 2000-08-30
US6083922A (en) 2000-07-04
BR9801008A (pt) 2001-03-20
WO1998043650A1 (fr) 1998-10-08
ZA982447B (en) 1999-01-26

Similar Documents

Publication Publication Date Title
US6083922A (en) Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
US5508269A (en) Aminoglycoside formulation for aerosolization
US6387886B1 (en) Method for the treatment of severe chronic bronchitis (bronchietasis) with an aerosolized antibiotic
JP4646489B2 (ja) 肺細菌感染症の治療及び予防のための吸入可能なアズトレオナム
US9345663B2 (en) Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
AU2002231244A1 (en) Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections
BG66328B1 (bg) Аерозолен състав на тобpамицин
US20230201309A1 (en) Compositions for the treatment of a respiratory condition
AU2004257632B2 (en) Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
Le Le et al. Consensus Summary of Aerosolized Antimicrobial Agents: Application of Guideline Criteria: Insights from the Society of Infectious Diseases Pharmacists
MXPA01006134A (en) Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic

Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
KB20 Patent renewed for 20 years
EXP Patent expired