IL123185A - Process for the manufacture of a pharmaceutical solid composition comprising enalapril sodium - Google Patents

Process for the manufacture of a pharmaceutical solid composition comprising enalapril sodium

Info

Publication number
IL123185A
IL123185A IL12318596A IL12318596A IL123185A IL 123185 A IL123185 A IL 123185A IL 12318596 A IL12318596 A IL 12318596A IL 12318596 A IL12318596 A IL 12318596A IL 123185 A IL123185 A IL 123185A
Authority
IL
Israel
Prior art keywords
sodium
enalapril
maleate
water
mixing
Prior art date
Application number
IL12318596A
Other languages
English (en)
Other versions
IL123185A0 (en
Original Assignee
Sherman Bernard Charles
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24034300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL123185(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sherman Bernard Charles filed Critical Sherman Bernard Charles
Publication of IL123185A0 publication Critical patent/IL123185A0/xx
Publication of IL123185A publication Critical patent/IL123185A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL12318596A 1995-08-04 1996-07-30 Process for the manufacture of a pharmaceutical solid composition comprising enalapril sodium IL123185A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/511,297 US5573780A (en) 1995-08-04 1995-08-04 Stable solid formulation of enalapril salt and process for preparation thereof
PCT/CA1996/000513 WO1997005881A1 (fr) 1995-08-04 1996-07-30 Formulation solide stable de sel d'enalapril et procede de preparation correspondant

Publications (2)

Publication Number Publication Date
IL123185A0 IL123185A0 (en) 1998-09-24
IL123185A true IL123185A (en) 2001-08-08

Family

ID=24034300

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12318596A IL123185A (en) 1995-08-04 1996-07-30 Process for the manufacture of a pharmaceutical solid composition comprising enalapril sodium

Country Status (14)

Country Link
US (2) US5573780A (fr)
EP (4) EP0841930B1 (fr)
JP (1) JP3290994B2 (fr)
AT (1) ATE288271T1 (fr)
AU (1) AU697696C (fr)
BR (1) BR9609964A (fr)
CA (1) CA2166001C (fr)
DE (4) DE69616072T2 (fr)
DK (1) DK0841930T3 (fr)
ES (4) ES2264912T1 (fr)
IL (1) IL123185A (fr)
NZ (1) NZ313576A (fr)
RU (1) RU2161970C2 (fr)
WO (1) WO1997005881A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573780A (en) * 1995-08-04 1996-11-12 Apotex Usa Inc. Stable solid formulation of enalapril salt and process for preparation thereof
ES2125198B1 (es) * 1997-05-13 1999-11-16 Vita Invest Sa Asociacion a dosis fija de un inhibidor de la enzima convertidora de angiotensina y de un antagonista de los canales de calcio, procedimiento para su preparacion y su utilizacion para el tratamiento de enfermees cardiovasculares.
US6296871B1 (en) * 1998-04-12 2001-10-02 Ranbaxy Laboratories Limited Stable solid pharmaceutical compositions containing enalapril maleate
US6153223A (en) * 1998-06-05 2000-11-28 Watson Pharmaceuticals, Inc. Stabilized pharmaceutical compositions
NZ333206A (en) 1998-12-08 2000-07-28 Bernard Charles Sherman Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor
US6637359B1 (en) * 1998-12-15 2003-10-28 Maritrans Inc. System and method for internally fitting a new inner hull to an existing outer hull to form a rebuilt double hull vessel
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
US6764694B1 (en) * 1999-08-31 2004-07-20 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
DE60312857T2 (de) * 2002-01-15 2008-01-17 Actavis Group Hf. Formulierungen von quinapril und verwandte ace-hemmer
US20030215526A1 (en) * 2002-03-08 2003-11-20 Scott Stofik Stable formulations of angiotensin converting enzyme (ACE) inhibitors
PL1948224T3 (pl) 2005-11-17 2014-10-31 Silverstone Pharma Est Trwały preparat amorficznych soli peryndoprylu, sposób ich wytwarzania, zwłaszcza wytwarzania w skali przemysłowej oraz ich zastosowanie w terapii nadciśnienia
WO2011161223A2 (fr) 2010-06-23 2011-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Formes pharmaceutiques à usage oral comprenant de la lercanidipine et de l'énalapril et leurs sels pharmaceutiquement acceptables
SI2654729T1 (sl) 2010-12-24 2016-08-31 Krka, D.D., Novo Mesto Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino
CN109350733A (zh) * 2018-06-08 2019-02-19 山东理工职业学院 一种马来酸依那普利片剂的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
SI9111842A (sl) * 1991-11-25 1998-04-30 Krka Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba
WO1994001093A1 (fr) * 1992-07-09 1994-01-20 Merck & Co., Inc. Pompe osmotique pour la liberation d'enalapril a porosite regulee
US5573780A (en) * 1995-08-04 1996-11-12 Apotex Usa Inc. Stable solid formulation of enalapril salt and process for preparation thereof

Also Published As

Publication number Publication date
EP1527780A1 (fr) 2005-05-04
CA2166001C (fr) 2005-12-27
EP1442746A1 (fr) 2004-08-04
EP0841930B1 (fr) 2005-02-02
EP1637142A2 (fr) 2006-03-22
EP0841930A1 (fr) 1998-05-20
DE69616072T2 (de) 2009-09-10
IL123185A0 (en) 1998-09-24
US5690962A (en) 1997-11-25
WO1997005881A1 (fr) 1997-02-20
ES2245275T1 (es) 2006-01-01
CA2166001A1 (fr) 1996-12-05
AU6608496A (en) 1997-03-05
ES2223315T1 (es) 2005-03-01
JP3290994B2 (ja) 2002-06-10
AU697696B2 (en) 1998-10-15
US5573780A (en) 1996-11-12
EP1637142A3 (fr) 2008-04-02
JPH10511103A (ja) 1998-10-27
ATE288271T1 (de) 2005-02-15
DK0841930T3 (da) 2005-04-25
DE69616072D1 (de) 2001-11-22
ES2236741T3 (es) 2005-07-16
NZ313576A (en) 1999-05-28
AU697696C (en) 2006-04-06
DE04076118T1 (de) 2005-02-10
BR9609964A (pt) 1999-02-02
RU2161970C2 (ru) 2001-01-20
DE05076813T1 (de) 2006-11-30
DE04078149T1 (de) 2005-12-29
ES2264912T1 (es) 2007-02-01

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees