DK0841930T3 - Stabilt fast præparat af enalaprilsalt og fremgangsmåde til fremstilling deraf - Google Patents

Stabilt fast præparat af enalaprilsalt og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0841930T3
DK0841930T3 DK96925615T DK96925615T DK0841930T3 DK 0841930 T3 DK0841930 T3 DK 0841930T3 DK 96925615 T DK96925615 T DK 96925615T DK 96925615 T DK96925615 T DK 96925615T DK 0841930 T3 DK0841930 T3 DK 0841930T3
Authority
DK
Denmark
Prior art keywords
enalapril
solid composition
preparation
stable solid
water
Prior art date
Application number
DK96925615T
Other languages
English (en)
Inventor
Bernard Charles Sherman
Original Assignee
Bernard Charles Sherman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24034300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0841930(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bernard Charles Sherman filed Critical Bernard Charles Sherman
Application granted granted Critical
Publication of DK0841930T3 publication Critical patent/DK0841930T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK96925615T 1995-08-04 1996-07-30 Stabilt fast præparat af enalaprilsalt og fremgangsmåde til fremstilling deraf DK0841930T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/511,297 US5573780A (en) 1995-08-04 1995-08-04 Stable solid formulation of enalapril salt and process for preparation thereof
PCT/CA1996/000513 WO1997005881A1 (en) 1995-08-04 1996-07-30 Stable solid formulation of enalapril salt and process for preparation thereof
EP96925615A EP0841930B1 (en) 1995-08-04 1996-07-30 Stable solid formulation of enalapril salt and process for preparation thereof

Publications (1)

Publication Number Publication Date
DK0841930T3 true DK0841930T3 (da) 2005-04-25

Family

ID=24034300

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96925615T DK0841930T3 (da) 1995-08-04 1996-07-30 Stabilt fast præparat af enalaprilsalt og fremgangsmåde til fremstilling deraf

Country Status (14)

Country Link
US (2) US5573780A (da)
EP (4) EP1442746A1 (da)
JP (1) JP3290994B2 (da)
AT (1) ATE288271T1 (da)
AU (1) AU697696C (da)
BR (1) BR9609964A (da)
CA (1) CA2166001C (da)
DE (4) DE05076813T1 (da)
DK (1) DK0841930T3 (da)
ES (4) ES2264912T1 (da)
IL (1) IL123185A (da)
NZ (1) NZ313576A (da)
RU (1) RU2161970C2 (da)
WO (1) WO1997005881A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573780A (en) * 1995-08-04 1996-11-12 Apotex Usa Inc. Stable solid formulation of enalapril salt and process for preparation thereof
ES2125198B1 (es) * 1997-05-13 1999-11-16 Vita Invest Sa Asociacion a dosis fija de un inhibidor de la enzima convertidora de angiotensina y de un antagonista de los canales de calcio, procedimiento para su preparacion y su utilizacion para el tratamiento de enfermees cardiovasculares.
US6296871B1 (en) * 1998-04-12 2001-10-02 Ranbaxy Laboratories Limited Stable solid pharmaceutical compositions containing enalapril maleate
US6153223A (en) * 1998-06-05 2000-11-28 Watson Pharmaceuticals, Inc. Stabilized pharmaceutical compositions
NZ333206A (en) * 1998-12-08 2000-07-28 Bernard Charles Sherman Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor
US6637359B1 (en) * 1998-12-15 2003-10-28 Maritrans Inc. System and method for internally fitting a new inner hull to an existing outer hull to form a rebuilt double hull vessel
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US6764694B1 (en) * 1999-08-31 2004-07-20 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
AU2003235579A1 (en) * 2002-01-15 2003-07-30 Delta Hf. Formulations of quinapril and related ace inhibitors
US20030215526A1 (en) * 2002-03-08 2003-11-20 Scott Stofik Stable formulations of angiotensin converting enzyme (ACE) inhibitors
PL1948224T3 (pl) 2005-11-17 2014-10-31 Silverstone Pharma Est Trwały preparat amorficznych soli peryndoprylu, sposób ich wytwarzania, zwłaszcza wytwarzania w skali przemysłowej oraz ich zastosowanie w terapii nadciśnienia
EP2585051B2 (en) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
EP2654729B1 (en) 2010-12-24 2016-05-04 KRKA, d.d., Novo mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid
CN109350733A (zh) * 2018-06-08 2019-02-19 山东理工职业学院 一种马来酸依那普利片剂的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
SI9111842A (sl) * 1991-11-25 1998-04-30 Krka Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba
WO1994001093A1 (en) * 1992-07-09 1994-01-20 Merck & Co., Inc. Controlled porosity osmotic enalapril pump
US5573780A (en) * 1995-08-04 1996-11-12 Apotex Usa Inc. Stable solid formulation of enalapril salt and process for preparation thereof

Also Published As

Publication number Publication date
JPH10511103A (ja) 1998-10-27
IL123185A (en) 2001-08-08
DE05076813T1 (de) 2006-11-30
WO1997005881A1 (en) 1997-02-20
AU6608496A (en) 1997-03-05
DE69616072D1 (de) 2001-11-22
DE04076118T1 (de) 2005-02-10
ES2245275T1 (es) 2006-01-01
EP1442746A1 (en) 2004-08-04
ES2236741T3 (es) 2005-07-16
RU2161970C2 (ru) 2001-01-20
JP3290994B2 (ja) 2002-06-10
ES2264912T1 (es) 2007-02-01
DE69616072T2 (de) 2009-09-10
ATE288271T1 (de) 2005-02-15
EP1527780A1 (en) 2005-05-04
CA2166001C (en) 2005-12-27
US5690962A (en) 1997-11-25
NZ313576A (en) 1999-05-28
EP1637142A3 (en) 2008-04-02
DE04078149T1 (de) 2005-12-29
EP0841930A1 (en) 1998-05-20
IL123185A0 (en) 1998-09-24
BR9609964A (pt) 1999-02-02
EP1637142A2 (en) 2006-03-22
EP0841930B1 (en) 2005-02-02
AU697696B2 (en) 1998-10-15
ES2223315T1 (es) 2005-03-01
CA2166001A1 (en) 1996-12-05
US5573780A (en) 1996-11-12
AU697696C (en) 2006-04-06

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