JPS55122713A - Tablet comprising antibacterial substance - Google Patents
Tablet comprising antibacterial substanceInfo
- Publication number
- JPS55122713A JPS55122713A JP2959979A JP2959979A JPS55122713A JP S55122713 A JPS55122713 A JP S55122713A JP 2959979 A JP2959979 A JP 2959979A JP 2959979 A JP2959979 A JP 2959979A JP S55122713 A JPS55122713 A JP S55122713A
- Authority
- JP
- Japan
- Prior art keywords
- tablet
- cellulose
- sulfamethoxazole
- trimethoprim
- granules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: The title tablet of small size, comprising Trimethoprim, Sulfamethoxazole, and hydroxyproply cellulose with a low substitution degree or calcium carboxymethyl cellulose.
CONSTITUTION: 1pt.wt. of Trimethoprim and 5W10pts.wt. of Sulfamethoxazole having an antibacterial action respectively are granulated by the dry method into granules. 1% by wt. or more based on the tablet weight of hydroxypropyl cellulose with a low substitution degree or calcium carboxymethyl cellulose is incorporated into the granules. An additive, e.g. Avicel, lactose, or maltose, is added if necessary, and tableted to give a tablet having improved disintegration, dissolution, and hardness even at a reduced size. The dry granulation method has advantages of a short process and higher operation efficiency compared with the wet method.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2959979A JPS55122713A (en) | 1979-03-14 | 1979-03-14 | Tablet comprising antibacterial substance |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2959979A JPS55122713A (en) | 1979-03-14 | 1979-03-14 | Tablet comprising antibacterial substance |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55122713A true JPS55122713A (en) | 1980-09-20 |
JPS5710086B2 JPS5710086B2 (en) | 1982-02-24 |
Family
ID=12280532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2959979A Granted JPS55122713A (en) | 1979-03-14 | 1979-03-14 | Tablet comprising antibacterial substance |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55122713A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63301816A (en) * | 1987-01-29 | 1988-12-08 | Takeda Chem Ind Ltd | Core-containing granule and production thereof |
CN105769883A (en) * | 2014-12-17 | 2016-07-20 | 康普药业股份有限公司 | Compound sulfamethoxazole dispersible tablet and preparation method thereof |
-
1979
- 1979-03-14 JP JP2959979A patent/JPS55122713A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63301816A (en) * | 1987-01-29 | 1988-12-08 | Takeda Chem Ind Ltd | Core-containing granule and production thereof |
JPH0832625B2 (en) * | 1987-01-29 | 1996-03-29 | 武田薬品工業株式会社 | Nucleated granule and method for producing the same |
CN105769883A (en) * | 2014-12-17 | 2016-07-20 | 康普药业股份有限公司 | Compound sulfamethoxazole dispersible tablet and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS5710086B2 (en) | 1982-02-24 |
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