IL119418A - Use of nk-1 receptor antagonists in combination with other agents in the preparation of anti-emetic medicaments, and pharmaceutical compositions comprising same - Google Patents
Use of nk-1 receptor antagonists in combination with other agents in the preparation of anti-emetic medicaments, and pharmaceutical compositions comprising sameInfo
- Publication number
- IL119418A IL119418A IL11941896A IL11941896A IL119418A IL 119418 A IL119418 A IL 119418A IL 11941896 A IL11941896 A IL 11941896A IL 11941896 A IL11941896 A IL 11941896A IL 119418 A IL119418 A IL 119418A
- Authority
- IL
- Israel
- Prior art keywords
- phenylpiperidine
- amino
- methoxybenzylamino
- methoxy
- azabicyclo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US572895P | 1995-10-20 | 1995-10-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL119418A0 IL119418A0 (en) | 1997-01-10 |
IL119418A true IL119418A (en) | 2001-07-24 |
Family
ID=21717419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11941896A IL119418A (en) | 1995-10-20 | 1996-10-14 | Use of nk-1 receptor antagonists in combination with other agents in the preparation of anti-emetic medicaments, and pharmaceutical compositions comprising same |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0769300A3 (de) |
JP (1) | JPH09110721A (de) |
CN (1) | CN1151893A (de) |
AU (1) | AU700841B2 (de) |
CA (1) | CA2188227C (de) |
IL (1) | IL119418A (de) |
NZ (1) | NZ299606A (de) |
TW (1) | TW458774B (de) |
ZA (1) | ZA968790B (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT533280E (pt) | 1991-09-20 | 2001-01-31 | Glaxo Group Ltd | Novas utilizacoes medicas para antagonistas de taquiquinina |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0360390A1 (de) | 1988-07-25 | 1990-03-28 | Glaxo Group Limited | Spirolactamderivate |
WO1990005525A1 (en) | 1988-11-23 | 1990-05-31 | Pfizer Inc. | Quinuclidine derivatives as substance p antagonists |
FI97540C (fi) | 1989-11-06 | 1997-01-10 | Sanofi Sa | Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi |
US5232929A (en) | 1990-11-28 | 1993-08-03 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use |
DK0550635T3 (da) | 1990-09-28 | 1995-09-04 | Pfizer | Cykliske forbindelser med kondeserede ringe, som er analoger til nitrogenholdige ikke-aromatiske het erocykliske forbindelser |
EP0566589A1 (de) | 1991-01-10 | 1993-10-27 | Pfizer Inc. | N-alkyl chinuclidiniumsalze als substanz-p-antagoniste |
EP0499313B1 (de) | 1991-02-11 | 1997-06-11 | MERCK SHARP & DOHME LTD. | Azabicyclische Verbindungen, diese enthaltende pharmazeutische Zubereitungen und ihre therapeutische Verwendung |
ATE115581T1 (de) | 1991-03-01 | 1994-12-15 | Pfizer | 1-azabicyclo(3.2.2>nonan-3-aminderivate. |
WO1992020661A1 (en) | 1991-05-22 | 1992-11-26 | Merck & Co., Inc. | N, n-diacylpiperazines |
RU2092486C1 (ru) | 1991-05-22 | 1997-10-10 | Пфайзер Инк. | Замещенные 3-аминохинуклидины |
DE69208877T2 (de) | 1991-05-31 | 1996-07-25 | Pfizer | Chinuclidinderivate |
CZ290475B6 (cs) | 1991-06-20 | 2002-07-17 | Pfizer Inc. | Fluoralkoxybenzylaminové deriváty heterocyklů obsahujících dusík, způsob jejich přípravy, meziprodukty tohoto postupu a pouľití těchto derivátů |
TW202432B (de) | 1991-06-21 | 1993-03-21 | Pfizer | |
US5288730A (en) | 1991-06-24 | 1994-02-22 | Merck Sharp & Dohme Limited | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
EP0593557B1 (de) | 1991-07-05 | 1996-01-31 | MERCK SHARP & DOHME LTD. | Aromatische verbindungen, diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische anwendung |
WO1993001169A2 (en) | 1991-07-05 | 1993-01-21 | Merck Sharp & Dohme Limited | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
WO1993001165A2 (en) | 1991-07-10 | 1993-01-21 | Merck Sharp & Dohme Limited | Aromatic compounds, compositions containing them and their use in therapy |
WO1993001159A1 (en) | 1991-07-10 | 1993-01-21 | Merck Sharp & Dohme Limited | Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy |
US5459270A (en) | 1991-08-20 | 1995-10-17 | Merck Sharp & Dohme Limited | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
PT533280E (pt) | 1991-09-20 | 2001-01-31 | Glaxo Group Ltd | Novas utilizacoes medicas para antagonistas de taquiquinina |
HU9400728D0 (en) | 1991-09-26 | 1994-06-28 | Pfizer | Fused tricyclic nitrogen containing heterocycles as substance p receptor antagonists |
HUT70741A (en) | 1991-11-12 | 1995-10-30 | Pfizer | Acyclic ethylenediamine derivatives as substance p receptor antagonists |
DE4143345B4 (de) | 1991-12-04 | 2007-03-22 | Rieter Ingolstadt Spinnereimaschinenbau Ag | Drehteller einer Spinnereivorbereitungsmaschine |
GB9201179D0 (en) | 1992-01-21 | 1992-03-11 | Glaxo Group Ltd | Chemical compounds |
JP2656702B2 (ja) | 1992-03-23 | 1997-09-24 | ファイザー製薬株式会社 | ペプチド性キヌクリジン |
EP1114823A3 (de) | 1992-08-19 | 2001-07-18 | Pfizer Inc. | Substituierte Benzylamin-Stickstoff enthaltende nichtaromatische Heterocyclen |
JP2656699B2 (ja) | 1992-10-21 | 1997-09-24 | ファイザー製薬株式会社 | 置換ベンジルアミノキヌクリジン |
PT675886E (pt) | 1992-12-10 | 2000-12-29 | Pfizer | Heterociclos nao aromaticos com substituintes aminometileno e sua utilizacao como antagonistas da substancia p |
AU6226494A (en) | 1993-03-04 | 1994-09-26 | Pfizer Inc. | Spiroazacyclic derivatives as substance p antagonists |
GB9305718D0 (en) | 1993-03-19 | 1993-05-05 | Glaxo Group Ltd | Medicaments |
US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
GB9315808D0 (en) | 1993-07-30 | 1993-09-15 | Merck Sharp & Dohme | Therapeutic agents |
GB9317987D0 (en) * | 1993-08-26 | 1993-10-13 | Glaxo Group Ltd | Chemical compounds |
IL111002A (en) | 1993-09-22 | 1998-09-24 | Glaxo Group Ltd | History of piperidine, their preparation and the pharmaceutical preparations containing them |
EP0739336B1 (de) | 1994-01-13 | 1998-08-26 | MERCK SHARP & DOHME LTD. | Gem-bissubstituierte azazyclische tachykinin-antagonisten |
US5728716A (en) | 1994-01-28 | 1998-03-17 | Merck Sharp & Dohme Limited | Aralkylamino substituted azacyclic therapeutic agents |
PE45195A1 (es) | 1994-03-03 | 1996-01-17 | Boehringer Ingelheim Kg | Derivado de aminoacido, procedimiento para su preparacion y composicion farmaceutica que lo contiene |
GB9525296D0 (en) * | 1995-12-11 | 1996-02-07 | Merck Sharp & Dohme | Therapeutic agents |
-
1996
- 1996-07-16 TW TW085108626A patent/TW458774B/zh not_active IP Right Cessation
- 1996-10-14 IL IL11941896A patent/IL119418A/en not_active IP Right Cessation
- 1996-10-17 CN CN96112447A patent/CN1151893A/zh active Pending
- 1996-10-17 EP EP96307533A patent/EP0769300A3/de not_active Withdrawn
- 1996-10-18 JP JP8297370A patent/JPH09110721A/ja active Pending
- 1996-10-18 NZ NZ299606A patent/NZ299606A/en unknown
- 1996-10-18 CA CA002188227A patent/CA2188227C/en not_active Expired - Fee Related
- 1996-10-18 AU AU70279/96A patent/AU700841B2/en not_active Ceased
- 1996-10-18 ZA ZA9608790A patent/ZA968790B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU700841B2 (en) | 1999-01-14 |
NZ299606A (en) | 2000-07-28 |
EP0769300A2 (de) | 1997-04-23 |
AU7027996A (en) | 1997-05-15 |
ZA968790B (en) | 1998-04-20 |
CA2188227C (en) | 2000-08-08 |
CA2188227A1 (en) | 1997-04-21 |
JPH09110721A (ja) | 1997-04-28 |
EP0769300A3 (de) | 1999-11-24 |
IL119418A0 (en) | 1997-01-10 |
TW458774B (en) | 2001-10-11 |
MX9605030A (es) | 1997-09-30 |
CN1151893A (zh) | 1997-06-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2164689C (en) | Nk-1 receptor antagonists and 5ht3 receptor antagonists for the treatment of emesis | |
EP0533280B2 (de) | Neue medizinische Indikation für Tachykinin-Antagonisten | |
CZ187097A3 (cs) | Farmaceutický prostředek | |
EP0627221A2 (de) | Substanz P Antagonisten zur Behandlung von Erbrechen | |
US20040006135A1 (en) | Combination treatment for depression and anxiety | |
US20150374712A1 (en) | Combinations of Dopamine D2 Receptor Blockade With Norepinephrine Reuptake Inhibition and with Norepinephrine Alpha 2 Receptor Blockade | |
CA2728514C (en) | Paediatric compositions for treating multiple sclerosis | |
US5519033A (en) | Azabicyclo derivatives for treatment of urinary incontinence | |
US6376507B1 (en) | NK-1 receptor antagonists for the treatment of neuronal injury and stroke | |
US6194436B1 (en) | NK-1 receptor antagonists for the treatment of cancer | |
EP1192952A2 (de) | Ein NK-3 rezeptorantagonisten und ein ZNS-penetrierende NK-1 rezeptorantagonisten enthaltende Zusammensetzung zur Behandlung von Depression und Angst | |
CA2188227C (en) | Combination antiemetic therapy using nk-1 receptor antagonists | |
EP0854720B1 (de) | Nk-1 rezeptor antagonisten in neurogener entzündung in gen-therapie | |
US20040001895A1 (en) | Combination treatment for depression and anxiety | |
WO1996014845A1 (en) | Nk-1 receptor antagonists for the treatment of eye disorders | |
AU2021200647A1 (en) | Paediatric compositions for treating multiple sclerosis | |
EP0659409A2 (de) | Substanz P Antagonisten zur Hemmung der Angiogenese | |
MXPA96005030A (en) | Antiemetic combination therapy using receptor antagonists n | |
EP1095655A2 (de) | NK-1 Rezeptor Antagonisten und Eletriptan zur Behandlung von Migräne |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
RH1 | Patent not in force |