IL119365A - Contrast medium containing a colloidal system charged with a dye - Google Patents

Contrast medium containing a colloidal system charged with a dye

Info

Publication number
IL119365A
IL119365A IL11936596A IL11936596A IL119365A IL 119365 A IL119365 A IL 119365A IL 11936596 A IL11936596 A IL 11936596A IL 11936596 A IL11936596 A IL 11936596A IL 119365 A IL119365 A IL 119365A
Authority
IL
Israel
Prior art keywords
dye
medium containing
contrast medium
colloidal system
system charged
Prior art date
Application number
IL11936596A
Other languages
English (en)
Other versions
IL119365A0 (en
Original Assignee
Diagnostikforschung Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostikforschung Inst filed Critical Diagnostikforschung Inst
Publication of IL119365A0 publication Critical patent/IL119365A0/xx
Publication of IL119365A publication Critical patent/IL119365A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0078—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion microemulsion, nanoemulsion

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
IL11936596A 1995-10-11 1996-10-07 Contrast medium containing a colloidal system charged with a dye IL119365A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19539409A DE19539409C2 (de) 1995-10-11 1995-10-11 Kontrastmittel für die Nahinfrarot-Diagnostik

Publications (2)

Publication Number Publication Date
IL119365A0 IL119365A0 (en) 1997-01-10
IL119365A true IL119365A (en) 2000-07-26

Family

ID=7775535

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11936596A IL119365A (en) 1995-10-11 1996-10-07 Contrast medium containing a colloidal system charged with a dye

Country Status (13)

Country Link
US (2) US6319488B1 (xx)
EP (1) EP0854732A2 (xx)
JP (1) JPH11504656A (xx)
KR (1) KR100290240B1 (xx)
CN (1) CN1075951C (xx)
AU (1) AU711266B2 (xx)
CA (1) CA2233995A1 (xx)
DE (1) DE19539409C2 (xx)
HU (1) HUP9900458A3 (xx)
IL (1) IL119365A (xx)
NO (1) NO981586L (xx)
WO (1) WO1997013490A2 (xx)
ZA (1) ZA968229B (xx)

Families Citing this family (35)

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DE4445065A1 (de) * 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung
DE19717904A1 (de) * 1997-04-23 1998-10-29 Diagnostikforschung Inst Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie
ATE257014T1 (de) * 1997-04-29 2004-01-15 Amersham Health As Lichtbilderzeugungskontrastmitteln
US6083486A (en) * 1998-05-14 2000-07-04 The General Hospital Corporation Intramolecularly-quenched near infrared fluorescent probes
KR20010075107A (ko) 1998-09-17 2001-08-09 다께다 가즈히꼬 광화학 요법 치료제
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US20030180221A1 (en) * 1998-09-18 2003-09-25 Schering Ag Near infrared fluorescent contrast agent and fluorescence imaging
US7547721B1 (en) 1998-09-18 2009-06-16 Bayer Schering Pharma Ag Near infrared fluorescent contrast agent and fluorescence imaging
EP1237593A1 (en) * 1999-11-22 2002-09-11 Epix Medical, Inc. Imaging sexual response
US7166719B2 (en) 2002-06-27 2007-01-23 Health Research, Inc. Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
DE10046215B4 (de) * 2000-09-19 2004-04-15 Institut für Chemo- und Biosensorik Münster e.V. i.Ins. Fluorochrome und deren Verwendung
US7003345B1 (en) 2000-10-17 2006-02-21 Lucid, Inc. System and method for enhancing microscope images of tissue using citric acid and agents of the like
US7139122B1 (en) * 2000-10-17 2006-11-21 Lucid, Inc. System and method for enhancing confocal reflectance images of tissue specimens
TWI240632B (en) 2001-07-30 2005-10-01 Epix Medical Inc Purified peptides for peptide-based multimeric targeted contrast agents
JP2003261464A (ja) * 2002-03-07 2003-09-16 Fuji Photo Film Co Ltd 近赤外蛍光造影剤および蛍光造影法
US20040133112A1 (en) * 2002-03-08 2004-07-08 Milind Rajadhyaksha System and method for macroscopic and confocal imaging of tissue
DK1593091T3 (da) * 2003-01-25 2013-10-28 Seno Medical Instr Inc Optoakustisk afbildning med høj kontrast ved anvendelse af ikke-sfæriske nanopartikler
JP2004269439A (ja) * 2003-03-10 2004-09-30 Motohiro Takeda センチネルリンパ節検出剤及び検出方法
WO2005082423A2 (en) * 2003-11-18 2005-09-09 Beth Israel Deaconess Medical Center Serum albumin conjugated to fluorescent substances for imaging
JP2005145921A (ja) * 2003-11-19 2005-06-09 Konica Minolta Medical & Graphic Inc 診断用蛍光造影剤及び蛍光造影診断方法
WO2006009786A2 (en) 2004-06-18 2006-01-26 Elmaleh David R Intravascular imaging device and uses thereof
US8227621B2 (en) * 2005-06-30 2012-07-24 Li-Cor, Inc. Cyanine dyes and methods of use
JP2008043396A (ja) * 2006-08-11 2008-02-28 Olympus Corp 内視鏡システム
GB2440910A (en) * 2006-08-18 2008-02-20 Robert Charles Wilson A marker for studying drug dynamics in vivo
KR100825939B1 (ko) * 2006-08-28 2008-04-29 한국과학기술연구원 근적외선 형광체가 결합된 양친성 고분자의 나노 입자를포함하는 암 진단용 조영제
JP2008148791A (ja) * 2006-12-14 2008-07-03 Olympus Corp 内視鏡システム
CN101723874B (zh) * 2008-10-31 2013-09-11 深圳迈瑞生物医疗电子股份有限公司 花菁类化合物及其在生物样品染色中的用途
CN101750476B (zh) * 2008-12-08 2015-06-03 深圳迈瑞生物医疗电子股份有限公司 血液分析试剂及其使用方法
AU2010236189B2 (en) * 2009-04-17 2015-01-29 Li-Cor, Inc. Fluorescent imaging with substituted cyanine dyes
CN102115456B (zh) * 2009-12-30 2014-08-20 深圳迈瑞生物医疗电子股份有限公司 花菁类化合物，包含所述化合物的组合物及其在细胞检测中的用途
WO2012054784A1 (en) 2010-10-20 2012-04-26 Li-Cor, Inc. Fluorescent imaging with substituted cyanine dyes
US9138492B2 (en) 2012-02-23 2015-09-22 Canon Kabushiki Kaisha Particle containing hydrophobic dye having cyanine structure, and contrast agent containing the particle
KR102132885B1 (ko) * 2018-09-03 2020-07-10 (주)씨바이오멕스 생체물질과 연결될 수 있는 양쪽성 형광물질
CN114149693B (zh) * 2021-11-14 2022-10-25 华中科技大学 一种用于血管网络标记成像的染料工作液、其制备和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916069A (en) * 1973-04-02 1975-10-28 Minnesota Mining & Mfg Reduced styryl/cyanine dye
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4859584A (en) * 1986-10-31 1989-08-22 Smithkline Beckman Corporation Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes
US4762701A (en) * 1986-10-31 1988-08-09 Smithkline Beckman Corporation In vivo cellular tracking
US5494793A (en) * 1986-12-15 1996-02-27 British Technology Group Usa Inc. Monomeric phthalocyanine reagents
ATE98020T1 (de) * 1986-12-15 1993-12-15 British Tech Group Usa Monomere phthalocyanin-reagenzien.
DE68927479T2 (de) * 1988-05-02 1997-04-03 Phanos Tech Inc Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen
EP0434727A4 (en) * 1988-09-08 1994-08-17 Ultra Diagnostic Corp Red-shifted phthalocyanine and tetrabenztriazaporphyrin reagents
US5208336A (en) * 1990-10-19 1993-05-04 Sterling Drug Inc. Selenomerocyanines and processes for preparation and methods of use and compositions thereof
US5433531A (en) * 1993-09-21 1995-07-18 Federal-Mogul Corporation Engine bearing surface treatment
US6238931B1 (en) * 1993-09-24 2001-05-29 Biosite Diagnostics, Inc. Fluorescence energy transfer in particles
DE4445065A1 (de) * 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung

Also Published As

Publication number Publication date
CN1075951C (zh) 2001-12-12
WO1997013490A3 (de) 1997-10-23
AU711266B2 (en) 1999-10-07
NO981586D0 (no) 1998-04-07
JPH11504656A (ja) 1999-04-27
US20020022004A1 (en) 2002-02-21
DE19539409C2 (de) 1999-02-18
WO1997013490A2 (de) 1997-04-17
IL119365A0 (en) 1997-01-10
KR19990044581A (ko) 1999-06-25
DE19539409A1 (de) 1997-04-17
HUP9900458A2 (hu) 1999-06-28
EP0854732A2 (de) 1998-07-29
ZA968229B (en) 1997-05-14
AU1589297A (en) 1997-04-30
KR100290240B1 (ko) 2001-05-15
NO981586L (no) 1998-04-07
US6319488B1 (en) 2001-11-20
CA2233995A1 (en) 1997-04-17
HUP9900458A3 (en) 1999-11-29
CN1199341A (zh) 1998-11-18

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