IL116064A - Sulphonamides their preparation intermediates thereof and pharmaceutical compositions containing them - Google Patents
Sulphonamides their preparation intermediates thereof and pharmaceutical compositions containing themInfo
- Publication number
- IL116064A IL116064A IL11606495A IL11606495A IL116064A IL 116064 A IL116064 A IL 116064A IL 11606495 A IL11606495 A IL 11606495A IL 11606495 A IL11606495 A IL 11606495A IL 116064 A IL116064 A IL 116064A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- alkoxy
- sulphonamides
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Bipolar Transistors (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Lubricants (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH355994 | 1994-11-25 | ||
| CH284295 | 1995-10-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL116064A0 IL116064A0 (en) | 1996-01-31 |
| IL116064A true IL116064A (en) | 2000-06-29 |
Family
ID=25691537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11606495A IL116064A (en) | 1994-11-25 | 1995-11-20 | Sulphonamides their preparation intermediates thereof and pharmaceutical compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0713875B1 (xx) |
| JP (1) | JP2755565B2 (xx) |
| KR (1) | KR100415030B1 (xx) |
| AT (1) | ATE199905T1 (xx) |
| AU (1) | AU691353B2 (xx) |
| CA (1) | CA2162630C (xx) |
| CZ (1) | CZ289920B6 (xx) |
| DE (1) | DE59509107D1 (xx) |
| DK (1) | DK0713875T3 (xx) |
| ES (1) | ES2156179T3 (xx) |
| FI (1) | FI117896B (xx) |
| GR (1) | GR3036065T3 (xx) |
| HK (1) | HK1012345A1 (xx) |
| HU (1) | HU225112B1 (xx) |
| IL (1) | IL116064A (xx) |
| MA (1) | MA23725A1 (xx) |
| MY (1) | MY119409A (xx) |
| NO (1) | NO307606B1 (xx) |
| NZ (1) | NZ280495A (xx) |
| PT (1) | PT713875E (xx) |
| RU (1) | RU2162084C2 (xx) |
| TW (1) | TW394763B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0826674A4 (en) * | 1995-04-03 | 1998-07-08 | Sumitomo Pharma | EFFECTIVE PYRIMIDINE DERIVATIVES AS PSYCHOTROPE, AND METHOD FOR THE PRODUCTION THEREOF |
| ATE267808T1 (de) * | 1997-08-19 | 2004-06-15 | Hoffmann La Roche | Verfahren zur herstellung von 2,5- disubstituierten pyridinen |
| TWI284642B (en) | 1999-01-18 | 2007-08-01 | Hoffmann La Roche | Novel heterocyclic sulfonamides |
| US6417360B1 (en) * | 1999-03-03 | 2002-07-09 | Hoffmann-La Roche Inc. | Heterocyclic sulfonamides |
| ATE380180T1 (de) * | 1999-09-03 | 2007-12-15 | Actelion Pharmaceuticals Ltd | Bis-sulfonamiden |
| HUP0204168A2 (hu) * | 1999-12-22 | 2003-04-28 | Actelion Pharmaceuticals Ltd. | Butin-diol-származékok, ilyeneket tartalmazó gyógyszerkészítmény és előállítása |
| WO2001081338A1 (en) * | 2000-04-25 | 2001-11-01 | Actelion Pharmaceuticals Ltd | Substituted sulfonylaminopyrimidines |
| US6387915B2 (en) | 2000-05-31 | 2002-05-14 | Pfizer Inc. | Isoxazole-sulfonamide endothelin antagonists |
| US6670362B2 (en) | 2000-09-20 | 2003-12-30 | Pfizer Inc. | Pyridazine endothelin antagonists |
| ATE312096T1 (de) | 2001-12-18 | 2005-12-15 | Neue verbindungen | |
| TWI328007B (en) | 2002-01-16 | 2010-08-01 | Astrazeneca Ab | Novel compounds |
| EP1454625A1 (en) * | 2003-03-06 | 2004-09-08 | Speedel Development AG | Pyridylsulfonamidyl-pyrimidines for the treatment of diabetic nephropathies |
| CN1930135B (zh) * | 2004-03-05 | 2011-12-28 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和p2x2/3拮抗剂的二氨基嘧啶 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2086544C1 (ru) * | 1991-06-13 | 1997-08-10 | Хоффманн-Ля Рош АГ | Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина |
| TW287160B (xx) * | 1992-12-10 | 1996-10-01 | Hoffmann La Roche | |
| TW394761B (en) * | 1993-06-28 | 2000-06-21 | Hoffmann La Roche | Novel Sulfonylamino Pyrimidines |
-
1995
- 1995-11-10 CA CA002162630A patent/CA2162630C/en not_active Expired - Lifetime
- 1995-11-13 DE DE59509107T patent/DE59509107D1/de not_active Expired - Lifetime
- 1995-11-13 PT PT95117833T patent/PT713875E/pt unknown
- 1995-11-13 DK DK95117833T patent/DK0713875T3/da active
- 1995-11-13 ES ES95117833T patent/ES2156179T3/es not_active Expired - Lifetime
- 1995-11-13 EP EP95117833A patent/EP0713875B1/de not_active Expired - Lifetime
- 1995-11-13 AT AT95117833T patent/ATE199905T1/de active
- 1995-11-16 AU AU37895/95A patent/AU691353B2/en not_active Ceased
- 1995-11-20 JP JP7300933A patent/JP2755565B2/ja not_active Expired - Lifetime
- 1995-11-20 HU HU9503311A patent/HU225112B1/hu not_active IP Right Cessation
- 1995-11-20 IL IL11606495A patent/IL116064A/xx not_active IP Right Cessation
- 1995-11-20 NZ NZ280495A patent/NZ280495A/en not_active IP Right Cessation
- 1995-11-21 MA MA24073A patent/MA23725A1/fr unknown
- 1995-11-22 KR KR1019950042804A patent/KR100415030B1/ko not_active IP Right Cessation
- 1995-11-22 NO NO954718A patent/NO307606B1/no not_active IP Right Cessation
- 1995-11-23 CZ CZ19953088A patent/CZ289920B6/cs not_active IP Right Cessation
- 1995-11-23 MY MYPI95003579A patent/MY119409A/en unknown
- 1995-11-24 FI FI955669A patent/FI117896B/fi not_active IP Right Cessation
- 1995-11-24 TW TW084112546A patent/TW394763B/zh not_active IP Right Cessation
- 1995-11-24 RU RU95120013/04A patent/RU2162084C2/ru not_active IP Right Cessation
-
1998
- 1998-12-15 HK HK98113451A patent/HK1012345A1/xx not_active IP Right Cessation
-
2001
- 2001-06-18 GR GR20010400908T patent/GR3036065T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA23725A1 (fr) | 1996-07-01 |
| MY119409A (en) | 2005-05-31 |
| KR960017644A (ko) | 1996-06-17 |
| ES2156179T3 (es) | 2001-06-16 |
| IL116064A0 (en) | 1996-01-31 |
| ATE199905T1 (de) | 2001-04-15 |
| AU691353B2 (en) | 1998-05-14 |
| AU3789595A (en) | 1996-05-30 |
| FI955669A (fi) | 1996-05-26 |
| EP0713875A1 (de) | 1996-05-29 |
| HK1012345A1 (en) | 1999-07-30 |
| NO954718L (no) | 1996-05-28 |
| TW394763B (en) | 2000-06-21 |
| DK0713875T3 (da) | 2001-06-11 |
| RU2162084C2 (ru) | 2001-01-20 |
| CZ289920B6 (cs) | 2002-04-17 |
| CA2162630A1 (en) | 1996-05-26 |
| NO954718D0 (no) | 1995-11-22 |
| GR3036065T3 (en) | 2001-09-28 |
| HU225112B1 (en) | 2006-06-28 |
| EP0713875B1 (de) | 2001-03-21 |
| CZ308895A3 (en) | 1997-07-16 |
| FI117896B (fi) | 2007-04-13 |
| NZ280495A (en) | 1996-12-20 |
| FI955669A0 (fi) | 1995-11-24 |
| HUT75030A (en) | 1997-03-28 |
| JPH08208625A (ja) | 1996-08-13 |
| PT713875E (pt) | 2001-09-28 |
| KR100415030B1 (ko) | 2004-05-17 |
| NO307606B1 (no) | 2000-05-02 |
| CA2162630C (en) | 2007-05-01 |
| JP2755565B2 (ja) | 1998-05-20 |
| DE59509107D1 (de) | 2001-04-26 |
| HU9503311D0 (en) | 1996-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |