IL115154A - Somatostatin peptides pharmaceutical compositions containing them and their use - Google Patents

Somatostatin peptides pharmaceutical compositions containing them and their use

Info

Publication number
IL115154A
IL115154A IL11515495A IL11515495A IL115154A IL 115154 A IL115154 A IL 115154A IL 11515495 A IL11515495 A IL 11515495A IL 11515495 A IL11515495 A IL 11515495A IL 115154 A IL115154 A IL 115154A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
somatostatin peptides
peptides pharmaceutical
somatostatin
Prior art date
Application number
IL11515495A
Other languages
English (en)
Other versions
IL115154A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL115154A0 publication Critical patent/IL115154A0/xx
Publication of IL115154A publication Critical patent/IL115154A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11515495A 1994-09-06 1995-09-04 Somatostatin peptides pharmaceutical compositions containing them and their use IL115154A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9417873A GB9417873D0 (en) 1994-09-06 1994-09-06 Organic compounds

Publications (2)

Publication Number Publication Date
IL115154A0 IL115154A0 (en) 1995-12-31
IL115154A true IL115154A (en) 2000-08-13

Family

ID=10760870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11515495A IL115154A (en) 1994-09-06 1995-09-04 Somatostatin peptides pharmaceutical compositions containing them and their use

Country Status (31)

Country Link
US (2) US6183721B1 (pl)
EP (1) EP0714911B1 (pl)
JP (1) JP3054346B2 (pl)
KR (1) KR100364111B1 (pl)
CN (1) CN1185252C (pl)
AT (1) ATE199561T1 (pl)
AU (1) AU703057B2 (pl)
BR (1) BR9503936A (pl)
CA (1) CA2157530C (pl)
CO (1) CO4410344A1 (pl)
CZ (1) CZ287012B6 (pl)
DE (1) DE69520256T2 (pl)
DK (1) DK0714911T3 (pl)
ES (1) ES2157309T3 (pl)
FI (1) FI117424B (pl)
GB (1) GB9417873D0 (pl)
GR (1) GR3035997T3 (pl)
HU (1) HU218284B (pl)
IL (1) IL115154A (pl)
NO (1) NO316569B1 (pl)
NZ (1) NZ272919A (pl)
PE (1) PE41496A1 (pl)
PL (1) PL182434B1 (pl)
PT (1) PT714911E (pl)
RU (1) RU2156774C2 (pl)
SG (1) SG50356A1 (pl)
SI (1) SI0714911T1 (pl)
SK (1) SK283774B6 (pl)
TR (1) TR199501094A2 (pl)
TW (1) TW387898B (pl)
ZA (1) ZA957475B (pl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AT405906B (de) * 1997-03-14 1999-12-27 Irene Dr Virgolini Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
LT2762140T (lt) 2001-02-19 2017-06-26 Novartis Ag Solidinių smegenų navikų gydymas rapamicino dariniu
CZ20032597A3 (cs) * 2001-02-26 2004-12-15 Bristol-Myers Squibb Pharma Company Analogy kyseliny askorbové pro metaloradiofarmaceutika
NZ530007A (en) * 2001-06-08 2006-02-24 Sod Conseils Rech Applic Somatostatin-dopamine chimeric analogues that retain both somatostatin and dopamine activity in vivo and display enhanced biological activity
ITMI20011708A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m
MXPA05000778A (es) 2002-07-18 2005-08-29 Helix Biopharma Corp Uso de ureasa para inhibir el crecimiento de celulas cancerosas.
JP2006522100A (ja) * 2003-03-10 2006-09-28 バイオジェン アイデック インク 標的化ペプチドに対するチオール媒介性薬物結合
CN102532321B (zh) 2004-06-18 2018-10-12 Ambrx公司 新颖抗原结合多肽和其用途
JP2008520616A (ja) * 2004-11-24 2008-06-19 アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 固相ペプチド合成および精製方法
EP2192922A4 (en) 2007-09-17 2010-09-29 Univ California INTERNATIONALIZING HUMAN MONOCLONAL ANTIBODIES TO PROMOTE IN SITU ON PROSTATAZELLES
CN105388287A (zh) 2011-03-11 2016-03-09 内布拉斯加大学董事委员会 冠状动脉疾病的生物标志物
EP2922578B1 (en) 2012-11-21 2018-12-12 Serene, Llc Tin-117m comprising somatostatin receptor binding compounds
CN103275189B (zh) * 2013-06-06 2014-08-06 深圳翰宇药业股份有限公司 一种用于肽树脂的裂解液及其在固相裂解合成生长抑素中的应用
EP3456700A1 (en) * 2013-10-18 2019-03-20 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
ES2975747T3 (es) 2015-11-30 2024-07-12 Univ California Administración de carga útil específica de tumor y activación inmunitaria utilizando un anticuerpo humano que se dirige a un antígeno de superficie celular de tumor altamente específico
WO2018044812A2 (en) 2016-08-29 2018-03-08 Fred Hutchinson Cancer Research Center Chelating platform for delivery of radionuclides
WO2018089829A1 (en) 2016-11-10 2018-05-17 Fortis Therapeutics, Inc. Cd46-specific effector cells and uses thereof
SI3568205T1 (sl) 2017-01-12 2023-12-29 Radiomedix Inc. Zdravljenje rakastih celic, ki prekomerno izražajo receptorje za somatostatin, z uporabo derivatov okreotida, kelatiranih v radioizotope
TW202015744A (zh) 2018-06-21 2020-05-01 法商艾普森藥品公司 用於放射性醫藥之含有體抑素類似物之組成物
TW202547563A (zh) * 2018-06-21 2025-12-16 德商愛利穆治療有限公司 用於放射性醫藥之含有體抑素類似物之組成物
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US20200030466A1 (en) 2018-07-25 2020-01-30 Advanced Accelerator Applications (Italy) Srl Stable, concentrated radionuclide complex solutions
JP7604397B2 (ja) 2019-05-20 2024-12-23 エンドサイト・インコーポレイテッド Psmaコンジュゲートの調製方法
AU2021320333A1 (en) 2020-08-07 2023-03-30 Fortis Therapeutics, Inc. Immunoconjugates targeting CD46 and methods of use thereof
WO2025058000A1 (ja) 2023-09-13 2025-03-20 東レ株式会社 癌の治療、予防及び/又は診断用医薬組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US5006643A (en) 1987-06-24 1991-04-09 The Dow Chemical Company Process for preparing isothiocyanato functionalized metal complexes
DE3728600A1 (de) 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium
WO1989011475A1 (en) * 1988-05-25 1989-11-30 The United States Of America, As Represented By Th Macrocyclic chelates and methods of use thereof
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
DE69026387T2 (de) 1989-09-29 1996-11-28 Neorx Corp., Seattle, Wash. Reduktion der nichtzielspezifischen retention von immunokonjugaten und ihren metaboliten
CA2131315A1 (en) * 1992-03-25 1993-09-30 Geert J. Ensing Method of intraoperatively detecting and locating tumoral tissues
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0607103A3 (en) * 1993-01-12 1997-07-09 Sandoz Ltd Somatostatin analogs containing chelating groups and their radiolabeled compositions.
CA2179990A1 (en) * 1994-01-12 1995-07-20 Gary Robert Bower Biological targeting agents
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds

Also Published As

Publication number Publication date
ZA957475B (en) 1997-03-06
SK283774B6 (sk) 2004-01-08
NO953457L (no) 1996-03-07
FI954147A0 (fi) 1995-09-04
PE41496A1 (es) 1996-10-14
HU9502577D0 (en) 1995-11-28
EP0714911A2 (en) 1996-06-05
PT714911E (pt) 2001-08-30
NO953457D0 (no) 1995-09-04
AU3041495A (en) 1996-03-21
CA2157530C (en) 2007-04-03
CN1185252C (zh) 2005-01-19
PL310274A1 (en) 1996-03-18
RU2156774C2 (ru) 2000-09-27
SK108895A3 (en) 1996-06-05
GR3035997T3 (en) 2001-09-28
AU703057B2 (en) 1999-03-11
GB9417873D0 (en) 1994-10-26
PL182434B1 (pl) 2002-01-31
IL115154A0 (en) 1995-12-31
NZ272919A (en) 1996-12-20
CZ226395A3 (en) 1996-03-13
US6183721B1 (en) 2001-02-06
TW387898B (en) 2000-04-21
CO4410344A1 (es) 1997-01-09
ATE199561T1 (de) 2001-03-15
SI0714911T1 (en) 2001-08-31
CZ287012B6 (en) 2000-08-16
FI954147L (fi) 1996-03-07
BR9503936A (pt) 1996-09-24
KR100364111B1 (ko) 2003-02-05
TR199501094A2 (tr) 1996-06-21
JPH0881498A (ja) 1996-03-26
SG50356A1 (en) 2000-11-21
EP0714911B1 (en) 2001-03-07
CA2157530A1 (en) 1996-03-07
JP3054346B2 (ja) 2000-06-19
DE69520256D1 (de) 2001-04-12
DE69520256T2 (de) 2001-08-09
NO316569B1 (no) 2004-02-23
DK0714911T3 (da) 2001-07-09
HU218284B (en) 2000-07-28
EP0714911A3 (en) 1996-08-21
HUT72895A (en) 1996-06-28
ES2157309T3 (es) 2001-08-16
FI117424B (fi) 2006-10-13
CN1127259A (zh) 1996-07-24
KR960010683A (ko) 1996-04-20
US6277356B1 (en) 2001-08-21

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
KB Patent renewed
EXP Patent expired