IL115154A - Somatostatin peptides pharmaceutical compositions containing them and their use - Google Patents

Somatostatin peptides pharmaceutical compositions containing them and their use

Info

Publication number
IL115154A
IL115154A IL11515495A IL11515495A IL115154A IL 115154 A IL115154 A IL 115154A IL 11515495 A IL11515495 A IL 11515495A IL 11515495 A IL11515495 A IL 11515495A IL 115154 A IL115154 A IL 115154A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
somatostatin peptides
peptides pharmaceutical
somatostatin
Prior art date
Application number
IL11515495A
Other languages
English (en)
Other versions
IL115154A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL115154A0 publication Critical patent/IL115154A0/xx
Publication of IL115154A publication Critical patent/IL115154A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11515495A 1994-09-06 1995-09-04 Somatostatin peptides pharmaceutical compositions containing them and their use IL115154A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9417873A GB9417873D0 (en) 1994-09-06 1994-09-06 Organic compounds

Publications (2)

Publication Number Publication Date
IL115154A0 IL115154A0 (en) 1995-12-31
IL115154A true IL115154A (en) 2000-08-13

Family

ID=10760870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11515495A IL115154A (en) 1994-09-06 1995-09-04 Somatostatin peptides pharmaceutical compositions containing them and their use

Country Status (31)

Country Link
US (2) US6183721B1 (xx)
EP (1) EP0714911B1 (xx)
JP (1) JP3054346B2 (xx)
KR (1) KR100364111B1 (xx)
CN (1) CN1185252C (xx)
AT (1) ATE199561T1 (xx)
AU (1) AU703057B2 (xx)
BR (1) BR9503936A (xx)
CA (1) CA2157530C (xx)
CO (1) CO4410344A1 (xx)
CZ (1) CZ287012B6 (xx)
DE (1) DE69520256T2 (xx)
DK (1) DK0714911T3 (xx)
ES (1) ES2157309T3 (xx)
FI (1) FI117424B (xx)
GB (1) GB9417873D0 (xx)
GR (1) GR3035997T3 (xx)
HU (1) HU218284B (xx)
IL (1) IL115154A (xx)
NO (1) NO316569B1 (xx)
NZ (1) NZ272919A (xx)
PE (1) PE41496A1 (xx)
PL (1) PL182434B1 (xx)
PT (1) PT714911E (xx)
RU (1) RU2156774C2 (xx)
SG (1) SG50356A1 (xx)
SI (1) SI0714911T1 (xx)
SK (1) SK283774B6 (xx)
TR (1) TR199501094A2 (xx)
TW (1) TW387898B (xx)
ZA (1) ZA957475B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AT405906B (de) * 1997-03-14 1999-12-27 Irene Dr Virgolini Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
NZ527692A (en) 2001-02-19 2005-05-27 Novartis Ag Cancer treatment
JP2004529884A (ja) * 2001-02-26 2004-09-30 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー 金属放射性医薬のためのアスコルビン酸類似体
ITMI20011708A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m
CN100577203C (zh) 2002-07-18 2010-01-06 赫利克斯生物药品公司 尿素酶用于抑制癌症细胞生长的用途
JP2006522100A (ja) * 2003-03-10 2006-09-28 バイオジェン アイデック インク 標的化ペプチドに対するチオール媒介性薬物結合
NZ551335A (en) 2004-06-18 2010-03-26 Ambrx Inc Antibodies and fragments thereof comprising an non naturally encoded amino acid coupled to a linker
JP2008520616A (ja) * 2004-11-24 2008-06-19 アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 固相ペプチド合成および精製方法
EP2192922A4 (en) 2007-09-17 2010-09-29 Univ California INTERNALIZING HUMAN MONOCLONAL ANTIBODIES TARGING PROSTATE <I> IN SITU CANCER CELLS </ I>
US20140170068A1 (en) 2011-03-11 2014-06-19 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
EP2922578B1 (en) 2012-11-21 2018-12-12 Serene, Llc Tin-117m comprising somatostatin receptor binding compounds
CN103275189B (zh) * 2013-06-06 2014-08-06 深圳翰宇药业股份有限公司 一种用于肽树脂的裂解液及其在固相裂解合成生长抑素中的应用
WO2017095823A1 (en) 2015-11-30 2017-06-08 The Regents Of The University Of California Tumor-specific payload delivery and immune activation using a human antibody targeting a highly specific tumor cell surface antigen
US11235076B2 (en) 2016-08-29 2022-02-01 Fred Hutchinson Cancer Research Center Chelating platform for delivery of radionuclides
AU2018207190B2 (en) 2017-01-12 2020-12-03 Orano Med Treatment of cancer cells overexpressing somatostatin receptors using ocreotide derivatives chelated to radioisotopes
TW202017600A (zh) * 2018-06-21 2020-05-16 法商艾普森藥品公司 用於放射性醫藥之含有體抑素類似物之組成物
TW202015744A (zh) * 2018-06-21 2020-05-01 法商艾普森藥品公司 用於放射性醫藥之含有體抑素類似物之組成物
US10596278B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
JP2023534765A (ja) 2020-08-07 2023-08-10 フォーティス セラピューティクス，インク． 免疫複合体を標的とするｃｄ４６およびその使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006643A (en) 1987-06-24 1991-04-09 The Dow Chemical Company Process for preparing isothiocyanato functionalized metal complexes
DE3728600A1 (de) 1987-08-27 1989-03-09 Hoechst Ag Verfahren zur markierung von substanzen mit technetium oder rhenium
ATE134999T1 (de) * 1988-05-25 1996-03-15 Us Commerce Makrocyclische chelate und verwendungsverfahren
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
WO1991004755A1 (en) 1989-09-29 1991-04-18 Neorx Corporation Methods for reducing non-target retention of immunoconjugates and metabolites thereof
WO1993018797A1 (en) * 1992-03-25 1993-09-30 Mallinckrodt Medical, Inc. Method of intraoperatively detecting and locating tumoral tissues
EP0607103A3 (en) * 1993-01-12 1997-07-09 Sandoz Ltd Somatostatin analogs containing chelating groups and their radiolabeled compositions.
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
US5705143A (en) * 1994-01-12 1998-01-06 Amersham International Plc Biological targeting agents
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds

Also Published As

Publication number Publication date
HU9502577D0 (en) 1995-11-28
NO316569B1 (no) 2004-02-23
DE69520256D1 (de) 2001-04-12
TR199501094A2 (tr) 1996-06-21
KR100364111B1 (ko) 2003-02-05
HU218284B (en) 2000-07-28
SK108895A3 (en) 1996-06-05
CN1185252C (zh) 2005-01-19
CZ226395A3 (en) 1996-03-13
NZ272919A (en) 1996-12-20
EP0714911A3 (en) 1996-08-21
CN1127259A (zh) 1996-07-24
EP0714911B1 (en) 2001-03-07
EP0714911A2 (en) 1996-06-05
HUT72895A (en) 1996-06-28
DE69520256T2 (de) 2001-08-09
NO953457D0 (no) 1995-09-04
FI954147A (fi) 1996-03-07
AU3041495A (en) 1996-03-21
FI954147A0 (fi) 1995-09-04
CA2157530C (en) 2007-04-03
PE41496A1 (es) 1996-10-14
ATE199561T1 (de) 2001-03-15
PT714911E (pt) 2001-08-30
DK0714911T3 (da) 2001-07-09
SG50356A1 (en) 2000-11-21
JPH0881498A (ja) 1996-03-26
BR9503936A (pt) 1996-09-24
CO4410344A1 (es) 1997-01-09
PL182434B1 (pl) 2002-01-31
TW387898B (en) 2000-04-21
US6277356B1 (en) 2001-08-21
RU2156774C2 (ru) 2000-09-27
SI0714911T1 (en) 2001-08-31
PL310274A1 (en) 1996-03-18
ZA957475B (en) 1997-03-06
GR3035997T3 (en) 2001-09-28
IL115154A0 (en) 1995-12-31
ES2157309T3 (es) 2001-08-16
CA2157530A1 (en) 1996-03-07
FI117424B (fi) 2006-10-13
NO953457L (no) 1996-03-07
JP3054346B2 (ja) 2000-06-19
US6183721B1 (en) 2001-02-06
GB9417873D0 (en) 1994-10-26
AU703057B2 (en) 1999-03-11
CZ287012B6 (en) 2000-08-16
SK283774B6 (sk) 2004-01-08
KR960010683A (ko) 1996-04-20

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
KB Patent renewed
EXP Patent expired