IL114852A - Pharmaceutically stable preparation of oxaliplatinum - Google Patents

Pharmaceutically stable preparation of oxaliplatinum

Info

Publication number
IL114852A
IL114852A IL11485295A IL11485295A IL114852A IL 114852 A IL114852 A IL 114852A IL 11485295 A IL11485295 A IL 11485295A IL 11485295 A IL11485295 A IL 11485295A IL 114852 A IL114852 A IL 114852A
Authority
IL
Israel
Prior art keywords
oxaliplatinum
pct
pharmaceutically stable
stable preparation
preparation
Prior art date
Application number
IL11485295A
Other languages
English (en)
Other versions
IL114852A0 (en
Inventor
Rolland-Yves Mauvernay
Houssam Ibrahim
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50845249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL114852(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of IL114852A0 publication Critical patent/IL114852A0/xx
Publication of IL114852A publication Critical patent/IL114852A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11485295A 1994-08-08 1995-08-07 Pharmaceutically stable preparation of oxaliplatinum IL114852A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH246294 1994-08-08

Publications (2)

Publication Number Publication Date
IL114852A0 IL114852A0 (en) 1995-12-08
IL114852A true IL114852A (en) 2000-02-29

Family

ID=50845249

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11485295A IL114852A (en) 1994-08-08 1995-08-07 Pharmaceutically stable preparation of oxaliplatinum

Country Status (17)

Country Link
US (1) US5716988A (ja)
EP (1) EP0774963B1 (ja)
JP (1) JP3547755B2 (ja)
KR (1) KR100365171B1 (ja)
CN (1) CN1138541C (ja)
AT (1) ATE197249T1 (ja)
AU (2) AU2989695A (ja)
BR (1) BR9508554A (ja)
CA (1) CA2196922C (ja)
CZ (1) CZ286714B6 (ja)
DE (1) DE69519300T2 (ja)
DK (1) DK0774963T3 (ja)
ES (1) ES2152412T3 (ja)
IL (1) IL114852A (ja)
RU (1) RU2148400C1 (ja)
UA (1) UA42779C2 (ja)
WO (1) WO1996004904A1 (ja)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100365171B1 (ko) 1994-08-08 2003-02-19 드바이오팜 에스.아. 약학적으로안정한옥살리플라티늄제제
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
AU762138B2 (en) * 1998-10-14 2003-06-19 Debiopharm S.A. Oxaliplatinum preparation packaging
GB9904386D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
BRPI0013613B8 (pt) * 1999-08-30 2021-05-25 Debiopharm Sa composição farmacêuticamente estável de oxaliplatina para administração parenteral.
US7070796B1 (en) * 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
US7012072B2 (en) * 2000-12-12 2006-03-14 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
EP1368022B1 (fr) * 2001-03-02 2007-06-20 Debiopharm S.A. Utilisation d'un flacon contenant une solution d'oxaliplatine
WO2003004505A1 (en) * 2001-07-02 2003-01-16 Debiopharm S.A. Oxaliplatin active substance with a very low content of oxalic acid
TWI315982B (en) 2001-07-19 2009-10-21 Novartis Ag Combinations comprising epothilones and pharmaceutical uses thereof
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
WO2005020980A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
JP2007512318A (ja) * 2003-11-25 2007-05-17 プラトコ・テクノロジーズ・（プロプライエタリー）・リミテッド 白金（ｉｉ）錯体並びに該錯体の製法及び使用
CN100471493C (zh) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 含有奥沙利铂的脂质体制剂
AU2005251588B2 (en) * 2004-06-09 2009-01-08 Taiho Pharmaceutical Co., Ltd. Antitumor effect fortifier, antitumor agent and method of therapy for cancer
CN101018797A (zh) 2004-09-01 2007-08-15 普拉托技术（私有）有限公司 铂(ⅱ)配合物的制备
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
WO2007029268A2 (en) 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
KR20080096682A (ko) * 2006-01-30 2008-10-31 플라트코 테크놀로지스 (프로프라이어터리) 리미티드 백금(ⅱ) 착물의 제조법
CN101442998B (zh) * 2006-03-16 2012-03-14 比奥纽默里克药物公司 抗癌活性加强化合物和制剂及其用法
BRPI0711385A2 (pt) 2006-05-09 2011-11-08 Novartis Ag combinação compreendendo um quelante de ferro e um agente anti-neoplástico e seu uso
MX2009007597A (es) * 2007-01-18 2009-07-22 Merck Patent Gmbh Terapia especifica y medicamento que utilizan ligandos de integrina para tratar el cancer.
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
WO2009087660A1 (en) * 2007-11-12 2009-07-16 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
WO2009113983A1 (en) 2008-03-14 2009-09-17 Bionumerik Pharmaceuticals, Inc. Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions
WO2009113989A1 (en) 2008-03-14 2009-09-17 Bionumerik Pharmaceuticals, Inc. Compositions and methods of use of compounds to increase cancer patient survival time
JP5759464B2 (ja) 2009-09-21 2015-08-05 ジェイダブリュー ファーマシューティカル コーポレイション オキサリプラチンのナノ粒子及びその製造方法
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
AU2013202575B1 (en) * 2012-01-04 2013-05-16 Hospira, Inc. Dexmedetomidine premix formulation
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
JP5314790B1 (ja) * 2012-07-09 2013-10-16 東和薬品株式会社 オキサリプラチン含有医薬組成物
SG10201701063WA (en) 2012-08-10 2017-04-27 Taiho Pharmaceutical Co Ltd Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
BR112015004984A2 (pt) 2012-09-07 2017-07-04 Coherus Biosciences Inc formulações aquosas estáveis de adalimumab
CN103690494B (zh) * 2013-11-29 2015-04-15 杭州华东医药集团新药研究院有限公司 一种低杂质含有奥沙利铂的组合物及其制备方法
CN106659706B (zh) 2014-06-23 2020-03-20 普莱康治疗有限公司 铂化合物、组合物及其用途
SI3865484T1 (sl) 2015-07-07 2024-05-31 H. Lundbeck A/S Zaviralec pde9 z imidazo pirazinonsko hrbtenico za zdravljenje perifernih bolezni
CN104940151A (zh) * 2015-07-23 2015-09-30 青岛蓝盛洋医药生物科技有限责任公司 一种抗癌药物奥沙利铂冻干粉针剂组合物
US11229702B1 (en) 2015-10-28 2022-01-25 Coherus Biosciences, Inc. High concentration formulations of adalimumab
WO2017184880A1 (en) * 2016-04-20 2017-10-26 Coherus Biosciences, Inc. A method of filling a container with no headspace
US10987353B2 (en) 2016-05-04 2021-04-27 The Wistar Institute Of Anatomy And Biology Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and platinum-based antineoplastic drugs
WO2018009424A1 (en) 2016-07-06 2018-01-11 Imara, Inc. Pde9 inhibitors for treatment of peripheral diseases
PT3630772T (pt) 2017-05-26 2024-02-05 Cardurion Pharmaceuticals Inc Métodos para fabricar e usar inibidores de pde9
JP2021526134A (ja) 2018-05-25 2021-09-30 イマラ インク． ６−［（３Ｓ，４Ｓ）−４−メチル−ｌ−（ピリミジン−２−イルメチル）ピロリジン−３−イル］−３−テトラヒドロピラン−４−イル−７Ｈ−イミダゾ［ｌ，５−Ａ］ピラジン−８−オンの一水和物および結晶形態

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
IL83380A (en) * 1987-07-30 1991-04-15 Teva Pharma Stable aqueous cisplatin solutions
NL8901433A (nl) * 1989-06-06 1991-01-02 Pharmachemie Bv Carboplatinpreparaat.
JPH04185601A (ja) * 1990-11-20 1992-07-02 Unitika Ltd 白金抗癌剤徐放性製剤
JP2673331B2 (ja) 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
AU5416394A (en) * 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
KR100365171B1 (ko) 1994-08-08 2003-02-19 드바이오팜 에스.아. 약학적으로안정한옥살리플라티늄제제

Also Published As

Publication number Publication date
EP0774963A1 (fr) 1997-05-28
US5716988A (en) 1998-02-10
CN1154654A (zh) 1997-07-16
IL114852A0 (en) 1995-12-08
WO1996004904A1 (fr) 1996-02-22
JP3547755B2 (ja) 2004-07-28
CN1138541C (zh) 2004-02-18
EP0774963B1 (fr) 2000-11-02
BR9508554A (pt) 1997-11-25
ATE197249T1 (de) 2000-11-15
UA42779C2 (uk) 2001-11-15
DE69519300T2 (de) 2001-05-31
KR970704434A (ko) 1997-09-06
RU2148400C1 (ru) 2000-05-10
JPH10508289A (ja) 1998-08-18
CZ286714B6 (en) 2000-06-14
ES2152412T3 (es) 2001-02-01
DK0774963T3 (da) 2001-01-29
AU2252499A (en) 2000-03-23
CA2196922C (fr) 2004-06-01
AU2989695A (en) 2000-03-07
KR100365171B1 (ko) 2003-02-19
CA2196922A1 (fr) 1996-02-22
DE69519300D1 (de) 2000-12-07
AU731981B2 (en) 2001-04-12
CZ37997A3 (en) 1997-06-11

Similar Documents

Publication Publication Date Title
IL114852A0 (en) A pharmaceutically stable preparation of oxaliplatinum
PL325825A1 (en) Microemulsion for use as a carrier for administering active compounds
IL150326A (en) Pediatric formula
MXPA02008654A (es) Formulaciones de ranolazina de liberacion prolongada.
RU94040387A (ru) Композиция, способствующая прекращению курения, никотиносодержащий распыляемый раствор, способ снижения потребности в курении табака, способ замены курения табака
NO20054324L (no) Anvendelse av ranolazin og minst ett pH-avhengig bindemiddel for fremstilling av ranolazinpreparater med depotvirkning
ES2007607A6 (es) Un procedimiento para la obtencion de un preparado de insulina para la administracion no parenteral.
AU2001288460A1 (en) Compositions for treating sexual dysfunction, containing an no-donor and an antioxidant
MY114389A (en) Aqueous risperidone formulations
KR920702216A (ko) 아세틸 d-카르니틴의 녹내장 치료에의 용도
HK1046090A1 (en) Use of l-carnitine and its alkanoyl derivatives asosmotic agents in solutions for medical use
NZ505821A (en) Pharmaceutical compositions of uridine triphosphate
GR3025742T3 (en) New pyrazine derivatives, their preparation and their use.
AU1852597A (en) Multifunctional fat absorption and blood cholesterol reducing formulation containing chitosan and nicotinic acid
DK1673074T3 (da) Flydende præparat, indeholdende tobramycin
IL141232A0 (en) Use of camptothecin derivatives, with reduced gastrointestinal toxicity
NZ507407A (en) Stable mitoxantrone solutions
AU2001289762A1 (en) Pharmaceutical extemporary compositions
ZA988820B (en) Use of delta-aminolaevulinic acid for the preparation of a topical medicament for the integral diagnosis and/or therapy of tumours in hollow organs
HK1036413A1 (en) Solution comprising prostaglandins and benzyl alcohol.
Lin et al. Toxicity of a single oral dose of N-ethylphenylacetamide in rats
ES2125800A1 (es) Conjunto de infusion final.
ES2128966A1 (es) Composiciones farmaceuticas parenterales a base de calcitoninas sinteticas, de ph controlado, con bajo indice de dolor y buena estabilidad.
MY104837A (en) Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
UA30696A (uk) Спосіб комплексного лікування пародонтиту

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired